Species

KNApSAcK Entry

Organism name Randia spinosa
Genus Randia
Family Rubiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Randia
Linked NCBI taxonomy ID 58445
Linked level genus

Family

Family in NCBI taxonomy Rubiaceae
ID 24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00031802 External link 512 Galioside
CHEMBL485798
CHEMBL1079679
CHEMBL1482711
CHEMBL2133850
14 / 2 / 5 No. 56 No. 36
C00003081 External link 512 Gardenoside
CHEMBL485798
CHEMBL1079679
CHEMBL1482711
CHEMBL2133850
C056587
14 / 2 / 5 No. 56 No. 36
C00003097 External link 512 Feretoside
/ Scandoside methyl ester
/ 6beta-Hydroxygeniposide
CHEMBL463096
CHEMBL516850
No. 100 No. 36
C00030094 External link 512 6alpha-Hydroxygeniposide
/ Methyl deacetylasperulosidate
/ Deacetylasperulosidic acid methyl ester
CHEMBL463096
CHEMBL516850
No. 100 No. 36
C00000320 External link 512 Geniposide
CHEMBL462894
CHEMBL1417490
CHEMBL1718933
C007835
3 / 2 / 3 3 / 0 No. 100 No. 36

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75496 Geminin Unclassified protein C00000320 C00003081 C00031802 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00003081 C00031802 1 / 1
Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 Enzyme C00003081 C00031802 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00003081 C00031802 1 / 4
Q92830 Histone acetyltransferase KAT2A Enzyme C00003081 C00031802 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00003081 C00031802 0 / 0
P06746 DNA polymerase beta Enzyme C00003081 C00031802 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003081 C00031802 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00003081 C00031802 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003081 C00031802 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00003081 C00031802 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00003081 C00031802 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00003081 C00031802 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00003081 C00031802 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00000320 2 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00000320 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00000320
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000320
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000320

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (8)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)