Species

KNApSAcK Entry

Organism name Vaccinium myritillus
Genus Vaccinium
Family Ericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Vaccinium
Linked NCBI taxonomy ID 13749
Linked level genus

Family

Family in NCBI taxonomy Ericaceae
ID 4345

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005367 External link 512 Avicularin
/ Avicularine
/ Avicularoside
/ Quercetin 3-alpha-L-arabinofuranoside
/ Quercetin 3-O-alpha-L-arabinofuranoside
CHEMBL471282
CHEMBL1590676
C041388
10 / 2 / 3 No. 2 No. 15
C00002935 External link 512 Procyanidin B4
/ Catechin-(4alpha->8)-epicatechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00009077 External link 512 Procyanidin B2
/ Epicathechin-(4beta->8)-epicathechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
C479580
20 / 7 / 8 10 / 0 No. 16 No. 19

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002935 C00009077 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002935 C00009077 0 / 1
Q15139 Serine/threonine-protein kinase D1 Pkd C00002935 C00009077 0 / 0
P41743 Protein kinase C iota type Iota C00002935 C00009077 0 / 0
P24723 Protein kinase C eta type Eta C00002935 C00009077 1 / 0
P05771 Protein kinase C beta type Alpha C00002935 C00009077 0 / 0
P05129 Protein kinase C gamma type Alpha C00002935 C00009077 1 / 1
Q05655 Protein kinase C delta type Delta C00002935 C00009077 0 / 0
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00002935 C00009077 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002935 C00009077 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002935 C00009077 3 / 3
P17252 Protein kinase C alpha type Alpha C00002935 C00009077 0 / 0
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00002935 C00009077 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002935 C00009077 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002935 C00009077 1 / 1
Q04759 Protein kinase C theta type Delta C00002935 C00009077 0 / 1
O94806 Serine/threonine-protein kinase D3 Pkd C00002935 C00009077 0 / 0
Q02156 Protein kinase C epsilon type Eta C00002935 C00009077 0 / 0
Q05513 Protein kinase C zeta type Iota C00002935 C00009077 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002935 C00009077 0 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00005367 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005367 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005367 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00005367 1 / 2
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00005367 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00005367 1 / 1
P15121 Aldose reductase Enzyme C00005367 0 / 0
O75496 Geminin Unclassified protein C00005367 0 / 0
P39748 Flap endonuclease 1 Enzyme C00005367 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00005367 0 / 0

10 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00009077
581 BAX, BCL2L4 BCL2-associated X protein C00009077
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00009077
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00009077
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00009077
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00009077
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00009077
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00009077
4240 MFGE8, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47 milk fat globule-EGF factor 8 protein C00009077
7153 TOP2A, TOP2, TP2A topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) C00009077

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#612219 Ewing sarcoma; es P11308
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (11)

KEGG name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00036 Osteosarcoma P08684 (marker)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)