PCIDB

Rheedia brasiliensis

Family in NCBI taxonomy	Clusiaceae
ID	55961

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class	rosids
ID	71275

KNApSAcK ID	name	ChEMBL link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	KCF-S cluster	phytochemical cluster
C00002961	Macluraxanthone / 3-Hydroxyblancoxanthone	CHEMBL478960	5 / 11 / 11	No. 18	No. 15
C00024193	Gerontoxanthone A	CHEMBL517514	7 / 10 / 6	No. 18	No. 15
C00034889	Rheediaxanthone A			No. 18	No. 15
C00037708	Pyranojacareubin			No. 18	No. 15
C00037343	Isorheediaxanthone B			No. 47	No. 15
C00037729	Rheediaxanthone B / (-)-Rheediaxanthone B			No. 47	No. 15

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q16637	Survival motor neuron protein	Unclassified protein	C00002961	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00024193	1 / 1
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00024193	2 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00024193	2 / 0
O75496	Geminin	Unclassified protein	C00024193	0 / 0
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00024193	4 / 2
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00024193	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00024193	1 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00002961	4 / 3
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002961	0 / 0
O00255	Menin	Unclassified protein	C00002961	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002961	1 / 2

OMIM	preferred title	UniProt
#114480	Breast cancer	P38398
#604370	Breast-ovarian cancer, familial, susceptibility to, 1; brovca1	P38398
#114500	Colorectal cancer; crc	P84022
#600274	Frontotemporal dementia; ftd	P10636
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#145000	Hyperparathyroidism 1; hrpt1	O00255
#613795	Loeys-dietz syndrome, type 3; lds3	P84022
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#257200	Niemann-pick disease, type a	P17405
#607616	Niemann-pick disease, type b	P17405
#167000	Ovarian cancer	P38398
#614320	Pancreatic cancer, susceptibility to, 4; pnca4	P38398
#260540	Parkinson-dementia syndrome	P10636
#172700	Pick disease of brain	P10636
#253300	Spinal muscular atrophy, type i; sma1	Q16637
#253550	Spinal muscular atrophy, type ii; sma2	Q16637
#253400	Spinal muscular atrophy, type iii; sma3	Q16637
#271150	Spinal muscular atrophy, type iv; sma4	Q16637
#183090	Spinocerebellar ataxia 2; sca2	Q99700
#601104	Supranuclear palsy, progressive, 1; psnp1	P10636
#278750	Xeroderma pigmentosum, variant type; xpv	Q9Y253

KEGG	name	UniProt
H00033	Adrenal carcinoma	O00255 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00058	Amyotrophic lateral sclerosis (ALS)	P10636 (related)
H00077	Progressive supranuclear palsy (PSP)	P10636 (related)
H00078	Frontotemporal lobar degeneration (FTLD)	P10636 (related)
H00137	Niemann-Pick disease (NPD) typeA and B	P17405 (related)
H00424	Defects in the degradation of sphingomyelin	P17405 (related)
H00027	Ovarian cancer	P38398 (related)
H00031	Breast cancer	P38398 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q03164 (related) Q03164 (marker)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)
H00455	Spinal muscular atrophy (SMA)	Q16637 (related)
H00063	Spinocerebellar ataxia (SCA)	Q99700 (related)
H00403	Disorders of nucleotide excision repair	Q9Y253 (related)