Species

KNApSAcK Entry

Organism name Moronobea coccinea
Genus Moronobea
Family Clusiaceae-Guttiferae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Moronobea coccinea
Linked NCBI taxonomy ID 198783
Linked level species

Family

Family in NCBI taxonomy Clusiaceae
ID 55961

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002991 External link 512 Garcinol
CHEMBL454261
CHEMBL502489
CHEMBL2087609
C054597
2 / 1 / 1 17 / 0 No. 123
C00031902 External link 512 Cambogin
/ Isogarcinol
CHEMBL458934
CHEMBL1077027
CHEMBL1098255
CHEMBL2087611
2 / 1 / 1 No. 123
C00042436 External link 512 Cycloxanthochymol
CHEMBL1098252
CHEMBL1098256
No. 123
C00048298 External link 512 7-epi-Garcinol
CHEMBL454261
CHEMBL502489
CHEMBL2087609
2 / 1 / 1 No. 123
C00048299 External link 512 7-epi-Isogarcinol
CHEMBL458934
CHEMBL1077027
CHEMBL1098255
CHEMBL2087611
2 / 1 / 1 No. 123
C00048353 External link 512 Coccinone A
/ (+)-Coccinone A
CHEMBL1253757
No. 123
C00048354 External link 512 Coccinone B
/ (-)-Coccinone B
No. 123
C00048355 External link 512 Coccinone C
/ (-)-Coccinone C
No. 123
C00048356 External link 512 Coccinone D
/ (-)-Coccinone D
No. 123
C00048357 External link 512 Coccinone E
/ (-)-Coccinone E
No. 123
C00048358 External link 512 Coccinone F
/ (-)-Coccinone F
No. 123
C00048359 External link 512 Coccinone G
/ (-)-Coccinone G
No. 123
C00048360 External link 512 Coccinone H
/ (+)-Coccinone H
No. 123

Human Protein / Gene in interactions

2 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q09472 Histone acetyltransferase p300 Enzyme C00002991 C00031902 C00048298 C00048299 1 / 1
Q92831 Histone acetyltransferase KAT2B Enzyme C00002991 C00031902 C00048298 C00048299 0 / 0

17 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
207 AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) C00002991
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00002991
637 BID, FP497 BH3 interacting domain death agonist C00002991
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00002991
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00002991
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00002991
2033 EP300, KAT3B, RSTS2, p300 E1A binding protein p300 (EC:2.3.1.48) C00002991
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00002991
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00002991
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00002991
4316 MMP7, MMP-7, MPSL1, PUMP-1 matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23) C00002991
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00002991
5295 PIK3R1, AGM7, GRB1, p85, p85-ALPHA phosphoinositide-3-kinase, regulatory subunit 1 (alpha) C00002991
5747 PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK protein tyrosine kinase 2 (EC:2.7.10.2) C00002991
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002991
6714 SRC, ASV, SRC1, c-SRC, p60-Src v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (EC:2.7.10.2) C00002991
7412 VCAM1, CD106, INCAM-100 vascular cell adhesion molecule 1 C00002991

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (1)

OMIM preferred title UniProt
#613684 Rubinstein-taybi syndrome 2; rsts2 Q09472

KEGG DISEASE (1)

KEGG name UniProt
H00504 Rubinstein-Taybi syndrome Q09472 (related)