Species

KNApSAcK Entry

Organism name Hypericum ascyron
Genus Hypericum
Family Hypericaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Hypericum ascyron
Linked NCBI taxonomy ID 210378
Linked level species

Family

Family in NCBI taxonomy Hypericaceae
ID 629714

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (16)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036375 External link 512 1,3,6,7-Tetrahydroxy-8-(3-methylbut-2-enyl)xanthone
CHEMBL519864
No. 15 No. 15
C00032369 External link 512 Toxyloxanthone B
CHEMBL482997
No. 24 No. 15
C00038230 External link 512 2-Methoxyxanthone
CHEMBL186609
7 / 7 / 5 No. 76 No. 15
C00029364 External link 512 Euxanthone
/ 1,7-Dihydroxyxanthone
CHEMBL389166
C404221
1 / 0 / 0 No. 76 No. 15
C00038190 External link 512 1-Hydroxy-7-methoxyxanthone
No. 76 No. 15
C00031793 External link 512 Friedelinol
CHEMBL229563
CHEMBL464649
C055670
No. 101 No. 52
C00034318 External link 512 Tomoeone B
/ (+)-Tomoeone B
No. 1011
C00034319 External link 512 Tomoeone C
/ (+)-Tomoeone C
No. 1011
C00034317 External link 512 Tomoeone A
/ (+)-Tomoeone A
No. 1011
C00034321 External link 512 Tomoeone E
/ (+)-Tomoeone E
No. 1011
C00034322 External link 512 Tomoeone F
/ (+)-Tomoeone F
No. 1011
C00034323 External link 512 Tomoeone G
/ (+)-Tomoeone G
No. 1011
C00034324 External link 512 Tomoeone H
/ (+)-Tomoeone H
No. 1011
C00034320 External link 512 Tomoeone D
/ (+)-Tomoeone D
No. 1011
C00033938 External link 512 Hypercalin C
/ (+)-Hypercalin C
No. 4633
C00002997 External link 512 Hypercalin B
No. 4633

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35610 Sterol O-acyltransferase 1 Enzyme C00029364 0 / 0
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00038230 1 / 1
P17405 Sphingomyelin phosphodiesterase Enzyme C00038230 2 / 2
O75496 Geminin Unclassified protein C00038230 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00038230 4 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00038230 0 / 0
Q99816 Tumor susceptibility gene 101 protein Unclassified protein C00038230 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00038230 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#300615 Brunner syndrome P21397
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398

KEGG DISEASE (5)

KEGG name UniProt
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00548 Brunner syndrome P21397 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)