Nigella sativa

• Index
• Plant Species
• Natural Activity
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Nigella sativa
Genus	Nigella
Family	Ranunculaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Nigella sativa
Linked NCBI taxonomy ID	555479
Linked level	species

Family

Family in NCBI taxonomy	Ranunculaceae
ID	3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Natural Activity

List (156)

Species	Activity
Nigella sativa L.	5-Lipoxygenase Inhibitor
Nigella sativa L.	Abortifacient
Nigella sativa L.	Achylia
Nigella sativa L.	Allergy
Nigella sativa L.	Ameba
Nigella sativa L.	Amebicide
Nigella sativa L.	Amenorrhea
Nigella sativa L.	Analgesic
Nigella sativa L.	Anesthetic
Nigella sativa L.	Anorexia
Nigella sativa L.	Antiamphetamine
Nigella sativa L.	Antibacterial
Nigella sativa L.	Antibilious
Nigella sativa L.	Anticancer
Nigella sativa L.	Antidote, Hg
Nigella sativa L.	Antihistaminic
Nigella sativa L.	Antioxidant
Nigella sativa L.	Antioxytocic
Nigella sativa L.	Antiseptic
Nigella sativa L.	Antispasmodic
Nigella sativa L.	Antiviral
Nigella sativa L.	Aperitif
Nigella sativa L.	Arthrosis
Nigella sativa L.	Ascites
Nigella sativa L.	Asthma
Nigella sativa L.	Bacillus
Nigella sativa L.	Bacteria
Nigella sativa L.	Biliousness
Nigella sativa L.	Bite
Nigella sativa L.	Bronchodilator
Nigella sativa L.	Bronchosis
Nigella sativa L.	Bronchospasm
Nigella sativa L.	Cachexia
Nigella sativa L.	Callus
Nigella sativa L.	Cancer
Nigella sativa L.	Cancer, abdomen
Nigella sativa L.	Cancer, colon
Nigella sativa L.	Cancer, eye
Nigella sativa L.	Cancer, liver
Nigella sativa L.	Cancer, nose
Nigella sativa L.	Cancer, uterus
Nigella sativa L.	Candida
Nigella sativa L.	Candidicide
Nigella sativa L.	Cardiodepressant
Nigella sativa L.	Cardiopathy
Nigella sativa L.	Carminative
Nigella sativa L.	Catarrh
Nigella sativa L.	Chemopreventive
Nigella sativa L.	Childbirth
Nigella sativa L.	Cholera
Nigella sativa L.	Choleretic
Nigella sativa L.	Cholicomimetic
Nigella sativa L.	CNS-Depressant
Nigella sativa L.	Cold
Nigella sativa L.	Colic
Nigella sativa L.	Constipation
Nigella sativa L.	Contraceptive
Nigella sativa L.	Corn
Nigella sativa L.	Cough
Nigella sativa L.	Cramp
Nigella sativa L.	Cyclooxygenase-Inhibitor
Nigella sativa L.	Dermatosis
Nigella sativa L.	Diabetes
Nigella sativa L.	Diaphoretic
Nigella sativa L.	Diarrhea
Nigella sativa L.	Digestive
Nigella sativa L.	Diuretic
Nigella sativa L.	Dysentery
Nigella sativa L.	Dysmenorrhea
Nigella sativa L.	Dyspepsia
Nigella sativa L.	Eczema
Nigella sativa L.	Emaciation
Nigella sativa L.	Emmenagogue
Nigella sativa L.	Enterosis
Nigella sativa L.	Eruption
Nigella sativa L.	Escherichia
Nigella sativa L.	Fever
Nigella sativa L.	Fibrosarcoma
Nigella sativa L.	Flu
Nigella sativa L.	Fungicide
Nigella sativa L.	Fungus
Nigella sativa L.	Gas
Nigella sativa L.	Gout
Nigella sativa L.	Headache
Nigella sativa L.	Hemorrhoid
Nigella sativa L.	Hepatoprotective
Nigella sativa L.	Hepatosis
Nigella sativa L.	High Blood Pressure
Nigella sativa L.	High Cholesterol
Nigella sativa L.	HIV
Nigella sativa L.	Hydrophobia
Nigella sativa L.	Hyperlipidemia
Nigella sativa L.	Hypotensive
Nigella sativa L.	Hypouricemic
Nigella sativa L.	Immunostimulant
Nigella sativa L.	Induration
Nigella sativa L.	Infection
Nigella sativa L.	Inflammation
Nigella sativa L.	Insecticide
Nigella sativa L.	Insectifuge
Nigella sativa L.	Jaundice
Nigella sativa L.	Lactagogue
Nigella sativa L.	Laxative
Nigella sativa L.	Leprosy
Nigella sativa L.	Leukemia
Nigella sativa L.	Leukorrhea
Nigella sativa L.	Lice
Nigella sativa L.	Malaria
Nigella sativa L.	Mycosis
Nigella sativa L.	Myrmecia
Nigella sativa L.	Nephrosis
Nigella sativa L.	Obesity
Nigella sativa L.	Ophthalmia
Nigella sativa L.	Orchosis
Nigella sativa L.	Pain
Nigella sativa L.	Paralysis
Nigella sativa L.	Parasite
Nigella sativa L.	Pediculicide
Nigella sativa L.	Phagocytotic
Nigella sativa L.	Pityriasis
Nigella sativa L.	PMS
Nigella sativa L.	Proctosis
Nigella sativa L.	Prolapse
Nigella sativa L.	Proteinuria
Nigella sativa L.	Protisticide
Nigella sativa L.	Puerperium
Nigella sativa L.	Pulmonosis
Nigella sativa L.	Respirastimulant
Nigella sativa L.	Rhinosis
Nigella sativa L.	Salmonella
Nigella sativa L.	Sclerosis
Nigella sativa L.	Secretagogue
Nigella sativa L.	Smallpox
Nigella sativa L.	Snakebite
Nigella sativa L.	Sniffle
Nigella sativa L.	Splenosis
Nigella sativa L.	Staphylococcus
Nigella sativa L.	Stimulant
Nigella sativa L.	Sting
Nigella sativa L.	Stomachache
Nigella sativa L.	Stomachic
Nigella sativa L.	Stomatosis
Nigella sativa L.	Swelling
Nigella sativa L.	Syphilis
Nigella sativa L.	Taenicide
Nigella sativa L.	Tonic
Nigella sativa L.	Toothache
Nigella sativa L.	toxic
Nigella sativa L.	Tumor
Nigella sativa L.	Uterocontractant
Nigella sativa L.	Vermifuge
Nigella sativa L.	Vibrio
Nigella sativa L.	Virus
Nigella sativa L.	Worm
Nigella sativa L.	Wound
Nigella sativa L.	Yeast

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00013848	Quercetin 3-glucosyl-(1->2)-galactosyl-(1->2)-glucoside / 3-[(O-beta-D-Glucopyranosyl-(1->2)-O-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one	CHEMBL1413586		13 / 7 / 5		No. 5	No. 15
C00013750	Kaempferol 3-glucosyl-(1->2)-galactosyl-(1->2)-glucoside / 3-[(O-beta-D-Glucopyranosyl-(1->2)-O-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 5	No. 15
C00013884	Quercetin 3-(6''''-feruloylglucosyl)-(1->2)-galactosyl-(1->2)-glucoside / 3-[[O-6-O-[(2E)-3-(4-Hydroxy-3-methoxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl-(1->2)-O-beta-D-galactopyranosyl-(1->2)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one					No. 7	No. 15
C00027370	Fuzitine					No. 286	No. 4
C00003038	(+)-R-Citronellol / (R)-beta-Citronellol / (R)-3,7-Dimethyl-6-octen-1-ol	CHEMBL395827 CHEMBL1907993 CHEMBL1907995		7 / 5 / 4		No. 1948	No. 34
C00028688	Nigellimine					No. 4224
C00028687	Nigellidine					No. 4604
C00039847	Nigellidine 4-O-sulfite					No. 4604
C00032075	Nigeglanine					No. 8218
C00028686	Nigellicine					No. 8820

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00013848	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00003038	0 / 3
P06746	DNA polymerase beta	Enzyme	C00013848	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00013848	1 / 1
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00013848	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00003038	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00003038	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00013848	1 / 1
Q9Y4X1	UDP-glucuronosyltransferase 2A1	Enzyme	C00003038	0 / 0
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00003038	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00013848	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00013848	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00013848	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00003038	5 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00013848	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00003038	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00013848	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00013848	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00013848	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00013848	0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions