Species

KNApSAcK Entry

Organism name Tribolium castaneum
Genus Tribolium
Family Poaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tribolium castaneum
Linked NCBI taxonomy ID 7070
Linked level species

Family

Family in NCBI taxonomy Tenebrionidae
ID 7065

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00010570 External link 512 8-Acetylharpagide
/ Harpagide 7-acetate
/ 8-O-Acetylharpagide
CHEMBL523290
CHEMBL595293
C077626
1 / 2 / 0 No. 56 No. 36
C00010569 External link 512 Harpagide
CHEMBL430183
C033250
1 / 0 / 3 No. 64 No. 36
C00003075 External link 512 Catalpol
CHEMBL513223
C078040
2 / 1 / 1 0 / 2 No. 64 No. 36

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00010569 0 / 3
Q92830 Histone acetyltransferase KAT2A Enzyme C00003075 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00010570 2 / 0
P03372 Estrogen receptor NR3A1 C00003075 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#615363 Estrogen resistance; estrr P03372
#613795 Loeys-dietz syndrome, type 3; lds3 P84022

KEGG DISEASE (4)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D007249 Inflammation C00003075
D019636 Neurodegenerative Diseases C00003075