| Organism name | Gentiana scabra |
|---|---|
| Genus | Gentiana |
| Family | Gentianaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Gentiana scabra |
|---|---|
| Linked NCBI taxonomy ID | 292393 |
| Linked level | species |
| Family in NCBI taxonomy | Gentianaceae |
|---|---|
| ID | 21472 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00036897
|
Chiratenol
/ (+)-Chiratenol |
No. 13 | No. 51 |
|
||||
|
C00003737
|
alpha-Amyrin
/ alpha-Amyrine / alpha-Amyrenol |
No. 23 | No. 51 |
|
||||
|
C00003749
|
Lupeol
/ Lupenol / (+)-Lupenol |
CHEMBL289191
CHEMBL459702 |
C010480
|
3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |
|
|
C00010604
|
Loganic acid
|
CHEMBL1081585
CHEMBL1079678 CHEMBL1356464 CHEMBL1452775 |
C002947
|
6 / 8 / 7 | No. 64 | No. 36 |
|
|
|
C00036339
|
(20S)-Dammara-13(17),24-dien-3-one
/ (+)-(20S)-Dammara-13(17),24-dien-3-one |
No. 91 |
|
|||||
|
C00045572
|
4'-O-beta-D-glucopyranosylgentiopicroside
/ (-)-4'-O-beta-D-glucopyranosylgentiopicroside |
No. 222 |
|
|||||
|
C00010794
|
Sweroside
|
CHEMBL456137
|
C049412
|
1 / 0 / 0 | No. 806 | No. 36 |
|
|
|
C00042064
|
1-O-beta-D-Glucopyranosyl-4-epiamplexine
/ (-)-1-O-beta-D-Glucopyranosyl-4-epiamplexine |
No. 955 |
|
|||||
|
C00003100
|
Swertiamarin
|
CHEMBL456138
|
C013270
|
1 / 0 / 0 | No. 1348 | No. 36 |
|
|
|
C00037276
|
Hop-17(21)-en-3-one
|
No. 1916 |
|
|||||
|
C00037275
|
Hop-17(21)-en-3beta-ol
|
No. 1916 |
|
|||||
|
C00031399
|
Swertiajaposide A
/ (-)-Swertiajaposide A |
No. 2193 |
|
|||||
|
C00042555
|
Gentiascabraside A
/ (-)-Gentiascabraside A |
No. 2193 |
|
|||||
|
C00042963
|
Scabrans G4
/ (-)-Scabrans G4 |
No. 3327 |
|
|||||
|
C00042964
|
Scabrans G5
/ (-)-Scabrans G5 |
No. 3327 |
|
|||||
|
C00003082
|
Gentiopicrin
/ Gentiopicroside |
CHEMBL508320
|
C012997
|
2 / 2 / 0 | 0 / 1 | No. 3781 | No. 36 |
|
|
C00035829
|
Gentiotrifloroside
/ (-)-Gentiotrifloroside |
No. 3875 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003082 C00010604 | 2 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003082 | 0 / 0 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003749 | 0 / 0 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003749 | 0 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003749 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00003100 | 0 / 0 |
| P60033 | CD81 antigen | Unclassified protein | C00010604 | 1 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00010604 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00010604 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00010794 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00010604 | 1 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00010604 | 0 / 3 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00003749
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00003749
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613496 | Immunodeficiency, common variable, 6; cvid6 |
P60033
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00088 | Common variable immunodeficiency (CVID) |
P60033
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D006528 | Carcinoma, Hepatocellular |
C00003749
|
| D009202 | Cardiomyopathies |
C00003749
|
| D006937 | Hypercholesterolemia |
C00003749
|
| D009374 | Neoplasms, Experimental |
C00003749
|
| D012878 | Skin Neoplasms |
C00003749
|
| D014947 | Wounds and Injuries |
C00003749
|
| D017114 | Liver Failure, Acute |
C00003082
|