Species

KNApSAcK Entry

Organism name Juniperus lucayana
Genus Juniperus
Family Cupressaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Juniperus barbadensis var. lucayana
Linked NCBI taxonomy ID 487037
Linked level varietas

Family

Family in NCBI taxonomy Cupressaceae
ID 3367

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Spermatophyta
ID 58024

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007234 External link 512 Katuranin
/ (+)-Aromadendrin
/ (+)-Dihydrokaempferol
/ (2R,3R)-2,3-Dihydro-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL9323
CHEMBL1933859
C080220
4 / 3 / 3 No. 42 No. 14
C00034371 External link 512 15-Hydroxyallocedrol
No. 161 No. 38
C00003112 External link 512 Cedrol
/ (+)-Cedrol
/ alpha-Cedrol
CHEMBL1592444
CHEMBL1974890
C078669
5 / 14 / 11 No. 161 No. 38
C00021966 External link 512 Allocedrol
/ allo-Cedrol
No. 161 No. 38
C00029679 External link 512 alpha-Bisabolol
CHEMBL519167
CHEMBL491186
CHEMBL477832
CHEMBL1096927
CHEMBL1171719
CHEMBL1561544
CHEMBL2104360
C004497
8 / 4 / 13 No. 541 No. 38
C00034367 External link 512 12-Hydroxywiddrol
/ (+)-12-Hydroxywiddrol
No. 3284
C00021963 External link 512 Widdrol
C078670
No. 3284
C00034391 External link 512 3-Hydroxypseudowiddran-6(7)-en-4-ol
/ (+)-3-Hydroxypseudowiddran-6(7)-en-4-ol
No. 3284
C00034455 External link 512 beta-Chamigrenic acid
No. 3683

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P28482 Mitogen-activated protein kinase 1 Erk C00003112 C00029679 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00003112 C00029679 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00007234 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003112 0 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00007234 1 / 1
O75496 Geminin Unclassified protein C00007234 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00029679 1 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00003112 3 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00029679 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00007234 2 / 2
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00029679 0 / 3
P02545 Prelamin-A/C Unclassified protein C00003112 11 / 10
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00029679 0 / 1
O00255 Menin Unclassified protein C00029679 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00029679 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (21)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#601626 Leukemia, acute myeloid; aml P36888
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (27)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00003 Acute myeloid leukemia (AML) P36888 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)