Myrothecium roridum
Species
KNApSAcK Entry
| Organism name | Myrothecium roridum |
|---|---|
| Genus | Myrothecium |
| Family | Incertae sedis |
| Kingdom | Fungi |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Myrothecium roridum |
|---|---|
| Linked NCBI taxonomy ID | 62969 |
| Linked level | species |
Family
| Family in NCBI taxonomy | |
|---|---|
| ID |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (26)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003179
|
Roridin A
|
CHEMBL341800
CHEMBL334648 CHEMBL585072 CHEMBL1079025 CHEMBL1992259 |
C038849
|
0 / 5 | No. 84 |
|
||
|
C00045517
|
14'-Hydroxymytoxin B
/ (+)-14'-Hydroxymytoxin B |
CHEMBL498987
|
No. 84 |
|
||||
|
C00003200
|
Verrucarin A
|
CHEMBL136985
CHEMBL1733059 CHEMBL2009497 CHEMBL2009907 |
C005348
|
7 / 7 / 4 | No. 84 |
|
||
|
C00012608
|
Myrotoxin A
/ 6',7'-Didehydro-6'-de(1-hydroxyethyl)-2',3'-epoxy-2',3',7',8'-tetrahydrosatratoxin H |
No. 84 |
|
|||||
|
C00012609
|
Myrotoxin B
/ 8-(Acetyloxy)-6',7'-didehydro-6'-de(1-hydroxyethyl)-2',3'-epoxy-2',3',7',8'-tetrahydrosatratoxin H |
No. 84 |
|
|||||
|
C00012610
|
Mytoxin A
/ (2'S,3'R)-13'-Deoxy-2',3'-epoxy-2',3',7',8'-tetrahydro-13'-oxosatratoxin H |
No. 84 |
|
|||||
|
C00012611
|
Mytoxin C
/ (2'S,3'R,12'S)-13'-Deoxy-2',3'-epoxy-2',3',7',8'-tetrahydro-13'-oxo-satratoxin H |
No. 84 |
|
|||||
|
C00012612
|
Mytoxin B
/ 13'-Deoxy-7',8'-dihydro-13'-oxo-satratoxin H |
CHEMBL464713
|
No. 84 |
|
||||
|
C00012615
|
Roridin D
/ 7'-Deoxo-2'-deoxy-2',3'-epoxy-7'-(1-hydroxyethyl)verrucarin A |
C407766
|
No. 84 |
|
||||
|
C00012619
|
Roridine E
/ [2'E,7'R(R)]-2',3'-Didehydro-7'-deoxo-2'-deoxy-7'-(1-hydroxyethyl)-verrucarin A |
CHEMBL337231
CHEMBL509175 |
C003797
|
No. 84 |
|
|||
|
C00012680
|
Roritoxin D
/ 7',8'-Didehydro-14'-deoxy-2',3'-epoxy-2',3'-dihydro-14'-oxovertisporin |
No. 84 |
|
|||||
|
C00012679
|
Roritoxin B
|
CHEMBL1978379
|
C060337
|
No. 84 |
|
|||
|
C00012678
|
Roritoxin A
/ 7',8'-Didehydrovertisporin |
No. 84 |
|
|||||
|
C00012672
|
Verrucarin J
/ Muconomycin B |
CHEMBL507752
CHEMBL576350 |
C035445
|
No. 84 |
|
|||
|
C00012673
|
PD 113,325
/ (2'E)-2',3'-Didehydro-2'-deoxy-13'-hydroxyverrucarin A |
C042904
|
No. 84 |
|
||||
|
C00012671
|
Verrucarin B
/ (2'S,3'R)-2'-Deoxy-2',3'-epoxyverrucarin A |
CHEMBL1079296
|
No. 84 |
|
||||
|
C00045522
|
16-Hydroxyroridin E
/ (-)-16-Hydroxyroridin E |
CHEMBL447144
|
No. 84 |
|
||||
|
C00012660
|
Trichoverritone
/ [4beta(2Z,4E),15(E)]- 4-[6-[2-(2,5-Dihydro-5-oxo-3-furanyl)ethoxy]-7-hydroxy-2,4-octadienoate] 15-(5-hydroxy-3-methyl-2-pentenoate) 12,13-epoxy-trichothec-9-ene-4,15-diol |
No. 612 |
|
|||||
|
C00012620
|
Roridin L 2
/ (+)-Roridin L-2 / [4beta(2Z,4E)]-4-[6-[2-(2,5-Dihydro-5-oxo-3-furanyl)ethoxy]-7-hydroxy-2,4-octadienoate] 12,13-epoxytrichothec-9-ene-4,15-diol |
CHEMBL1988456
|
No. 612 |
|
||||
|
C00012621
|
16-Hydroxyroridin L2
/ [4beta(2Z,4E)]-4-[6-[2-(2,5-Dihydro-5-oxo-3-furanyl)ethoxy]-7-hydroxy-2,4-octadienoate]12,13-epoxytrichothec-9-ene-4,15,16-triol |
No. 612 |
|
|||||
|
C00003195
|
Trichodermin
|
CHEMBL1714827
CHEMBL2001648 |
D014243
|
7 / 4 / 4 | No. 1091 |
|
||
|
C00012646
|
Roridin C
/ Trichodermol / 12,13-Epoxy-trichothec-9-en-4beta-ol |
CHEMBL2047177
|
No. 1262 |
|
||||
|
C00012657
|
7alpha-Hydroxytrichodermol
|
C047728
|
No. 1262 |
|
||||
|
C00012681
|
Roritoxin C
/ 7',8'-Didehydro-14'-deoxy-2',3':9,10-diepoxy-2',3',9,10-tetrahydro-14'-oxovertisporin |
No. 4107 |
|
|||||
|
C00023672
|
Wortmannin
|
CHEMBL428496
CHEMBL295038 CHEMBL1418590 CHEMBL1474372 |
C009687
|
131 / 97 / 89 | 122 / 11 | No. 4941 |
|
|
|
C00045512
|
12,13-Deoxyroridin E
/ (-)-12,13-Deoxyroridin E |
CHEMBL475690
|
No. 8583 |
|
Human Protein / Gene in interactions
133 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00003195 C00003200 C00023672 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003195 C00003200 C00023672 | 1 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003195 C00003200 C00023672 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00003195 C00003200 C00023672 | 0 / 0 |
| P07900 | Heat shock protein HSP 90-alpha | Other cytosolic protein | C00003200 C00023672 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003195 C00023672 | 2 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003200 C00023672 | 4 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00003200 C00023672 | 1 / 1 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00023672 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00023672 | 2 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00023672 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00023672 | 2 / 2 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | C00023672 | 0 / 0 |
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00023672 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00023672 | 0 / 0 |
| O15530 | 3-phosphoinositide-dependent protein kinase 1 | Pdk1 | C00023672 | 0 / 0 |
| P41240 | Tyrosine-protein kinase CSK | Csk | C00023672 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00023672 | 1 / 1 |
| P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Enzyme | C00023672 | 9 / 1 |
| P45984 | Mitogen-activated protein kinase 9 | Jnk | C00023672 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00023672 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00023672 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00023672 | 0 / 0 |
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00023672 | 0 / 0 |
| Q8IWQ3 | Serine/threonine-protein kinase BRSK2 | CAMK serine/threonine protein kinase BRSK subfamily | C00023672 | 0 / 0 |
| P27448 | MAP/microtubule affinity-regulating kinase 3 | CAMK serine/threonine protein kinase MARK subfamily | C00023672 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00023672 | 11 / 10 |
| Q8TDX7 | Serine/threonine-protein kinase Nek7 | Nek | C00023672 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00023672 | 3 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00023672 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00023672 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00023672 | 0 / 1 |
| P23443 | Ribosomal protein S6 kinase beta-1 | p70 | C00023672 | 0 / 0 |
| Q9UQB9 | Aurora kinase C | Aur | C00023672 | 1 / 1 |
| Q9HBH9 | MAP kinase-interacting serine/threonine-protein kinase 2 | CAMK serine/threonine protein kinase MNK subfamily | C00023672 | 0 / 0 |
| Q9NQU5 | Serine/threonine-protein kinase PAK 6 | STE serine/threonine protein kinase PAKB subfamily | C00023672 | 0 / 0 |
| Q16644 | MAP kinase-activated protein kinase 3 | CAMK serine/threonine protein kinase MAPKAPK | C00023672 | 0 / 0 |
| Q9H422 | Homeodomain-interacting protein kinase 3 | CMGC dual-specificity kinase HIPK | C00023672 | 0 / 0 |
| Q14680 | Maternal embryonic leucine zipper kinase | Melk | C00023672 | 0 / 0 |
| Q9NYY3 | Serine/threonine-protein kinase PLK2 | Plk2 | C00023672 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00023672 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00023672 | 2 / 3 |
| Q15746 | Myosin light chain kinase, smooth muscle | Mlck | C00023672 | 1 / 1 |
| Q13188 | Serine/threonine-protein kinase 3 | STE serine/threonine protein kinase MST subfamily | C00023672 | 0 / 0 |
| P31751 | RAC-beta serine/threonine-protein kinase | Akt | C00023672 | 2 / 2 |
| O75582 | Ribosomal protein S6 kinase alpha-5 | CAMK serine/threonine protein kinase MSKB subfamily | C00023672 | 0 / 0 |
| O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | Other serine/threonine protein kinase | C00023672 | 0 / 0 |
| Q16513 | Serine/threonine-protein kinase N2 | Pkn | C00023672 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00023672 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00023672 | 0 / 0 |
| Q8N5S9 | Calcium/calmodulin-dependent protein kinase kinase 1 | META serine/threonine protein kinase subfamily | C00023672 | 0 / 0 |
| Q9P286 | Serine/threonine-protein kinase PAK 7 | STE serine/threonine protein kinase PAKB subfamily | C00023672 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00023672 | 0 / 0 |
| Q96SB4 | SRSF protein kinase 1 | Srpk | C00023672 | 0 / 0 |
| Q92630 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 | CMGC dual-specificity kinase DYRK2 | C00023672 | 0 / 0 |
| O43781 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | CMGC dual-specificity kinase DYRK2 | C00023672 | 0 / 0 |
| O96013 | Serine/threonine-protein kinase PAK 4 | STE serine/threonine protein kinase PAKB subfamily | C00023672 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00023672 | 0 / 0 |
| Q9P1W9 | Serine/threonine-protein kinase pim-2 | Pim | C00023672 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00023672 | 7 / 37 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00023672 | 0 / 0 |
| Q15418 | Ribosomal protein S6 kinase alpha-1 | Rskb | C00023672 | 0 / 0 |
| O15264 | Mitogen-activated protein kinase 13 | p38 | C00023672 | 0 / 0 |
| P53779 | Mitogen-activated protein kinase 10 | Jnk | C00023672 | 0 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003195 | 0 / 0 |
| Q9H1R3 | Myosin light chain kinase 2, skeletal/cardiac muscle | Mlck | C00023672 | 1 / 0 |
| P51955 | Serine/threonine-protein kinase Nek2 | Nek | C00023672 | 0 / 0 |
| Q96RR4 | Calcium/calmodulin-dependent protein kinase kinase 2 | META serine/threonine protein kinase subfamily | C00023672 | 0 / 0 |
| Q9H4B4 | Serine/threonine-protein kinase PLK3 | PLK serine/threonine protein kinase subfamily | C00023672 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00023672 | 7 / 3 |
| Q9BUB5 | MAP kinase-interacting serine/threonine-protein kinase 1 | CAMK serine/threonine protein kinase MNK subfamily | C00023672 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00023672 | 1 / 2 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00023672 | 1 / 2 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00023672 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00023672 | 0 / 0 |
| P48730 | Casein kinase I isoform delta | Ck1 | C00023672 | 1 / 0 |
| Q96GD4 | Aurora kinase B | Aur | C00023672 | 0 / 0 |
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00023672 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00023672 | 0 / 0 |
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00023672 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00023672 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00023672 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00023672 | 2 / 2 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00023672 | 5 / 2 |
| P53350 | Serine/threonine-protein kinase PLK1 | PLK serine/threonine protein kinase subfamily | C00023672 | 0 / 0 |
| Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00023672 | 0 / 0 |
| O75116 | Rho-associated protein kinase 2 | Rock | C00023672 | 0 / 0 |
| O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | Enzyme | C00023672 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00023672 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00023672 | 0 / 0 |
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00023672 | 4 / 1 |
| Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial | Pdhk | C00023672 | 0 / 0 |
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00023672 | 0 / 0 |
| P51812 | Ribosomal protein S6 kinase alpha-3 | Rskb | C00023672 | 2 / 2 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00023672 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00023672 | 0 / 1 |
| Q9HC98 | Serine/threonine-protein kinase Nek6 | Nek | C00023672 | 0 / 0 |
| Q9H2X6 | Homeodomain-interacting protein kinase 2 | CMGC dual-specificity kinase HIPK | C00023672 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00023672 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00023672 | 4 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00023672 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00023672 | 4 / 3 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00023672 | 0 / 0 |
| P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | Enzyme | C00023672 | 0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00023672 | 0 / 1 |
| O96017 | Serine/threonine-protein kinase Chk2 | Rad53 | C00023672 | 4 / 1 |
| Q14012 | Calcium/calmodulin-dependent protein kinase type 1 | Camk1 | C00023672 | 0 / 0 |
| Q02750 | Dual specificity mitogen-activated protein kinase kinase 1 | Ste7 | C00023672 | 1 / 1 |
| P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Enzyme | C00023672 | 0 / 0 |
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00023672 | 0 / 0 |
| Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | CMGC dual-specificity kinase DYRK1 | C00023672 | 1 / 0 |
| P53778 | Mitogen-activated protein kinase 12 | p38 | C00023672 | 0 / 0 |
| O00418 | Eukaryotic elongation factor 2 kinase | Atypical serine/threonine protein kinase alpha subfamily | C00023672 | 0 / 0 |
| Q8TD08 | Mitogen-activated protein kinase 15 | Mapk | C00023672 | 0 / 0 |
| Q86V86 | Serine/threonine-protein kinase pim-3 | Pim | C00023672 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00023672 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00023672 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00023672 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00023672 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00023672 | 0 / 0 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00023672 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00023672 | 2 / 5 |
| P20248 | Cyclin-A2 | Other cytosolic protein | C00023672 | 0 / 0 |
| P78396 | Cyclin-A1 | Other cytosolic protein | C00023672 | 0 / 0 |
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00023672 | 0 / 0 |
| P68400 | Casein kinase II subunit alpha | Ck2 | C00023672 | 0 / 0 |
| P19784 | Casein kinase II subunit alpha' | Ck2 | C00023672 | 0 / 0 |
| P67870 | Casein kinase II subunit beta | REG serine/threonine protein kinase family | C00023672 | 0 / 0 |
| P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | Enzyme | C00023672 | 2 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00023672 | 0 / 0 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00003195 | 0 / 3 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00023672 | 2 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00023672 | 1 / 0 |
122 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
C00023672
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00023672
|
| 248 | ALPI, IAP | alkaline phosphatase, intestinal (EC:3.1.3.1) |
C00023672
|
| 472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00023672
|
| 572 | BAD, BBC2, BCL2L8 | BCL2-associated agonist of cell death |
C00023672
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00023672
|
| 9564 | BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas | breast cancer anti-estrogen resistance 1 |
C00023672
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00023672
|
| 8678 | BECN1, ATG6, VPS30, beclin1 | beclin 1, autophagy related |
C00023672
|
| 329 | BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, c-IAP1, cIAP1 | baculoviral IAP repeat containing 2 |
C00023672
|
| 330 | BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 | baculoviral IAP repeat containing 3 |
C00023672
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00023672
|
| 727 | C5, C5a, C5b, CPAMD4 | complement component 5 |
C00023672
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00023672
|
| 841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00023672
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00023672
|
| 857 | CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV | caveolin 1, caveolae protein, 22kDa |
C00023672
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00023672
|
| 894 | CCND2, KIAK0002 | cyclin D2 |
C00023672
|
| 1232 | CCR3, CC-CKR-3, CD193, CKR3, CMKBR3 | chemokine (C-C motif) receptor 3 |
C00023672
|
| 948 | CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3 | CD36 molecule (thrombospondin receptor) |
C00023672
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00023672
|
| 1027 | CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1 | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
C00023672
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00023672
|
| 1111 | CHEK1, CHK1 | checkpoint kinase 1 (EC:2.7.11.1) |
C00023672
|
| 11200 | CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1 | checkpoint kinase 2 (EC:2.7.11.1) |
C00023672
|
| 80781 | COL18A1, KNO, KNO1, KS | collagen, type XVIII, alpha 1 |
C00023672
|
| 1278 | COL1A2, OI4 | collagen, type I, alpha 2 |
C00023672
|
| 1385 | CREB1, CREB | cAMP responsive element binding protein 1 |
C00023672
|
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00023672
|
| 2920 | CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2 | chemokine (C-X-C motif) ligand 2 |
C00023672
|
| 3579 | CXCR2, CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB | chemokine (C-X-C motif) receptor 2 |
C00023672
|
| 199974 | CYP4Z1, CYP4A20 | cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1) |
C00023672
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00023672
|
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) |
C00023672
|
| 1978 | EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I | eukaryotic translation initiation factor 4E binding protein 1 |
C00023672
|
| 2057 | EPOR, EPO-R | erythropoietin receptor |
C00023672
|
| 2152 | F3, CD142, TF, TFA | coagulation factor III (thromboplastin, tissue factor) |
C00023672
|
| 356 | FASLG, ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6 | Fas ligand (TNF superfamily, member 6) |
C00023672
|
| 2252 | FGF7, HBGF-7, KGF | fibroblast growth factor 7 |
C00023672
|
| 2308 | FOXO1, FKH1, FKHR, FOXO1A | forkhead box O1 |
C00023672
|
| 2309 | FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A | forkhead box O3 |
C00023672
|
| 4303 | FOXO4, AFX, AFX1, MLLT7 | forkhead box O4 |
C00023672
|
| 9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00023672
|
| 2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00023672
|
| 3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00023672
|
| 3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00023672
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00023672
|
| 3297 | HSF1, HSTF1 | heat shock transcription factor 1 |
C00023672
|
| 692420 |
C00023672
|
||
| 3303 | HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 | heat shock 70kDa protein 1A |
C00023672
|
| 3309 | HSPA5, BIP, GRP78, MIF2 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
C00023672
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00023672
|
| 3479 | IGF1, IGF-I, IGF1A, IGFI | insulin-like growth factor 1 (somatomedin C) |
C00023672
|
| 3592 | IL12A, CLMF, IL-12A, NFSK, NKSF1, P35 | interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) |
C00023672
|
| 3593 | IL12B, CLMF, CLMF2, IL-12B, NKSF, NKSF2 | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) |
C00023672
|
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha |
C00023672
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00023672
|
| 51561 | IL23A, IL-23, IL-23A, IL23P19, P19, SGRF | interleukin 23, alpha subunit p19 |
C00023672
|
| 3562 | IL3, IL-3, MCGF, MULTI-CSF | interleukin 3 (colony-stimulating factor, multiple) |
C00023672
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00023672
|
| 3630 | INS, IDDM2, ILPR, IRDN, MODY10 | insulin |
C00023672
|
| 3685 | ITGAV, CD51, MSK8, VNRA, VTNR | integrin, alpha V |
C00023672
|
| 3689 | ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
C00023672
|
| 3690 | ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
C00023672
|
| 3756 | KCNH1, EAG, EAG1, Kv10.1, h-eag | potassium voltage-gated channel, subfamily H (eag-related), member 1 |
C00023672
|
| 3978 | LIG1 | ligase I, DNA, ATP-dependent (EC:6.5.1.1) |
C00023672
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00023672
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00023672
|
| 4170 | MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT | myeloid cell leukemia sequence 1 (BCL2-related) |
C00023672
|
| 4193 | MDM2, ACTFS, HDMX, hdm2 | MDM2 oncogene, E3 ubiquitin protein ligase |
C00023672
|
| 406991 | MIR21, MIRN21, hsa-mir-21, miR-21, miRNA21 | microRNA 21 |
C00023672
|
| 4321 | MMP12, HME, ME, MME, MMP-12 | matrix metallopeptidase 12 (macrophage elastase) (EC:3.4.24.65) |
C00023672
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00023672
|
| 4353 | MPO | myeloperoxidase (EC:1.11.2.2) |
C00023672
|
| 4504 | MT3, GIF, GIFB, GRIF, ZnMT3 | metallothionein 3 |
C00023672
|
| 2475 | MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1 | mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1) |
C00023672
|
| 4548 | MTR, HMAG, MS, cblG | 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13) |
C00023672
|
| 4613 | MYCN, MODED, MYCNOT, N-myc, NMYC, ODED, bHLHe37 | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
C00023672
|
| 58498 | MYL7, MYL2A, MYLC2A | myosin, light chain 7, regulatory |
C00023672
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00023672
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00023672
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00023672
|
| 2516 | NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3 | nuclear receptor subfamily 5, group A, member 1 |
C00023672
|
| 4922 | NTS, NMN-125, NN, NT, NT/N, NTS1 | neurotensin |
C00023672
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00023672
|
| 27250 | PDCD4, H731 | programmed cell death 4 (neoplastic transformation inhibitor) |
C00023672
|
| 3651 | PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1 | pancreatic and duodenal homeobox 1 |
C00023672
|
| 5290 | PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (EC:2.7.11.1 2.7.1.153) |
C00023672
|
| 5291 | PIK3CB, P110BETA, PI3K, PI3KBETA, PIK3C1 | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta (EC:2.7.1.153) |
C00023672
|
| 5295 | PIK3R1, AGM7, GRB1, p85, p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
C00023672
|
| 10761 | PLAC1, CT92, OOSP2L | placenta-specific 1 |
C00023672
|
| 8493 | PPM1D, PP2C-DELTA, WIP1 | protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16) |
C00023672
|
| 5580 | PRKCD, MAY1, PKCD, nPKC-delta | protein kinase C, delta (EC:2.7.10.2 2.7.11.13) |
C00023672
|
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) |
C00023672
|
| 5731 | PTGER1, EP1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
C00023672
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00023672
|
| 5747 | PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK | protein tyrosine kinase 2 (EC:2.7.10.2) |
C00023672
|
| 5829 | PXN | paxillin |
C00023672
|
| 5887 | RAD23B, HHR23B, HR23B, P58 | RAD23 homolog B (S. cerevisiae) |
C00023672
|
| 10111 | RAD50, NBSLD, RAD502, hRad50 | RAD50 homolog (S. cerevisiae) |
C00023672
|
| 5906 | RAP1A, KREV-1, KREV1, RAP1, SMGP21 | RAP1A, member of RAS oncogene family |
C00023672
|
| 6194 | RPS6, S6 | ribosomal protein S6 |
C00023672
|
| 6199 | RPS6KB2, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb | ribosomal protein S6 kinase, 70kDa, polypeptide 2 (EC:2.7.11.1) |
C00023672
|
| 7857 | SCG2, CHGC, EM66, SN, SgII | secretogranin II |
C00023672
|
| 871 | SERPINH1, AsTP3, CBP1, CBP2, HSP47, OI10, PPROM, RA-A47, SERPINH2, gp46 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
C00023672
|
| 140885 | SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP | signal-regulatory protein alpha (EC:3.1.3.48) |
C00023672
|
| 23411 | SIRT1, SIR2L1 | sirtuin 1 |
C00023672
|
| 6528 | SLC5A5, NIS, TDH1 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
C00023672
|
| 6531 | SLC6A3, DAT, DAT1, PKDYS | solute carrier family 6 (neurotransmitter transporter), member 3 |
C00023672
|
| 6667 | SP1 | Sp1 transcription factor |
C00023672
|
| 412 | STS, ARSC, ARSC1, ASC, ES, SSDD, XLI | steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2) |
C00023672
|
| 7077 | TIMP2, CSC-21K, DDC8 | TIMP metallopeptidase inhibitor 2 |
C00023672
|
| 7082 | TJP1, ZO-1 | tight junction protein 1 |
C00023672
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00023672
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00023672
|
| 7161 | TP73, P73 | tumor protein p73 |
C00023672
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00023672
|
| 7520 | XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
C00023672
|
| 2547 | XRCC6, CTC75, CTCBF, G22P1, KU70, ML8, TLAA | X-ray repair complementing defective repair in Chinese hamster cells 6 |
C00023672
|
| 10413 | YAP1, YAP, YAP2, YAP65, YKI | Yes-associated protein 1 |
C00023672
|
| 7702 | ZNF143, SBF, STAF, pHZ-1 | zinc finger protein 143 |
C00023672
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (97)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #615224 | Advanced sleep phase syndrome, familial, 2; fasps2 |
P48730
|
| #615214 | Agammaglobulinemia 7, autosomal recessive; agm7 |
P27986
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #613780 | Aortic aneurysm, familial thoracic 7; aat7 |
Q15746
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114480 | Breast cancer |
O96017
P31749 P42336 |
| #615279 | Cardiofaciocutaneous syndrome 3; cfc3 |
Q02750
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #192600 | Cardiomyopathy, familial hypertrophic, 1; cmh1 |
Q9H1R3
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #303600 | Coffin-lowry syndrome; cls |
P51812
|
| #114500 | Colorectal cancer; crc |
P31749
P42336 P84022 Q14191 |
| #612918 | Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi |
P42336
|
| #615108 | Cowden syndrome 5; cws5 |
P42336
|
| #615109 | Cowden syndrome 6; cws6 |
P31749
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #125853 | Diabetes mellitus, noninsulin-dependent; niddm |
P31751
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #114550 | Hepatocellular carcinoma |
P42336
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #240900 | Hypoinsulinemic hypoglycemia with hemihypertrophy; hihghh |
P31751
|
| #182000 | Keratosis, seborrheic |
P42336
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #609265 | Li-fraumeni syndrome 2; lfs2 |
O96017
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P04637
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #602501 | Megalencephaly-capillary malformation-polymicrogyria syndrome; mcap |
P42336
|
| #603387 | Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome; mpph |
P42336
|
| #614104 | Mental retardation, autosomal dominant 7; mrd7 |
Q13627
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300844 | Mental retardation, x-linked 19; mrx19 |
P51812
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259500 | Osteogenic sarcoma |
O96017
|
| #167000 | Ovarian cancer |
P42336
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #176807 | Prostate cancer |
O96017
|
| #176920 | Proteus syndrome |
P31749
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #269880 | Short syndrome |
P27986
|
| #243060 | Spermatogenic failure 5; spgf5 |
Q9UQB9
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
KEGG DISEASE (92)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00881 | Li-Fraumeni syndrome |
O96017
(related)
P04637 (related) |
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P31751 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
P31751 (related) P42336 (related) |
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00539 | PTEN hamartoma tumor syndrome (PHTS) |
P31749
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00480 | Non-syndromic X-linked mental retardation |
P51812
(related)
Q99714 (related) |
| H00574 | Coffin-Lowry syndrome (CLS) |
P51812
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
P53779
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00523 | Noonan syndrome and related disorders |
Q02750
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00296 | Defects in RecQ helicases |
Q14191
(related)
|
| H00801 | Familial thoracic aortic aneurysm and dissection (TAAD) |
Q15746
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H01282 | Spermatogenic failure |
Q9UQB9
(related)
|
Diseases related to CTD interactions
16 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000230 | Adenocarcinoma |
C00023672
|
| D001943 | Breast Neoplasms |
C00023672
|
| D005234 | Fatty Liver |
C00023672
|
| D006930 | Hyperalgesia |
C00023672
|
| D009336 | Necrosis |
C00023672
|
| D009361 | Neoplasm Invasiveness |
C00023672
|
| D009362 | Neoplasm Metastasis |
C00023672
|
| D010051 | Ovarian Neoplasms |
C00023672
|
| D010146 | Pain |
C00023672
|
| D011041 | Poisoning |
C00023672
|
| D013927 | Thrombosis |
C00023672
|
| D054537 | Atrioventricular Block |
C00003179
|
| D007249 | Inflammation |
C00003179
|
| D061219 | Olfactory Nerve Injuries |
C00003179
|
| D012220 | Rhinitis |
C00003179
|
| D012848 | Sinoatrial Block |
C00003179
|