Species

KNApSAcK Entry

Organism name Hymenoclea salsola
Genus Hymenoclea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Asteraceae
Linked NCBI taxonomy ID 4210
Linked level family

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00006933 External link 512 2',4',6'-Trihydroxychalcone
CHEMBL129371
2 / 0 / 3 No. 92 No. 13
C00003239 External link 512 Coronopilin
CHEMBL248564
11 / 12 / 41 No. 340 No. 38
C00003210 External link 512 Ambrosin
CHEMBL115843
CHEMBL1730820
C010675
12 / 10 / 7 No. 495 No. 38
C00003303 External link 512 Hymenolin
CHEMBL309932
CHEMBL519097
No. 755 No. 38
C00021142 External link 512 Neoambrosin
No. 3701

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00003210 C00003239 0 / 0
Q99700 Ataxin-2 Unclassified protein C00003210 C00003239 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003210 C00003239 2 / 0
O75496 Geminin Unclassified protein C00003210 C00003239 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003210 C00003239 0 / 3
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003210 C00003239 1 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003210 C00003239 0 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00003239 7 / 37
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003239 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00003210 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003210 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003210 0 / 0
P10145 Interleukin-8 Secreted protein C00003239 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00006933 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00006933 0 / 3
P38398 Breast cancer type 1 susceptibility protein Enzyme C00003210 4 / 2
P51531 Probable global transcription activator SNF2L2 Unclassified protein C00003210 1 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00003239 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#114500 Colorectal cancer; crc P84022
#133239 Esophageal cancer P04637
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#601358 Nicolaides-baraitser syndrome; ncbrs P51531
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260500 Papilloma of choroid plexus; cpp P04637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (42)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
P35354 (related)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
P38398 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
P38398 (related)
H00032 Thyroid cancer P04637 (related)
Q06710 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
P35354 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)