Species

KNApSAcK Entry

Organism name Serratula strangulata
Genus Serratula
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Serratula strangulata
Linked NCBI taxonomy ID 324596
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00013826 External link 512 6-Hydroxykaempferol 4'-methyl ether 7-glucoside
/ 3,5,6-Trihydroxy-4'-methoxyflavone-7-beta-D-glucoside
/ 7-(beta-D-Glucopyranosyloxy)-3,5,6-trihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 2 No. 15
C00004571 External link 512 Kaempferol 7,4'-dimethyl ether
/ 3,5-Dihydroxy-7,4'-dimethoxyflavone
/ 3,5-Dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 3 No. 15
C00033543 External link 512 20-Hydroxyecdysone
CHEMBL224128
CHEMBL490151
CHEMBL477132
CHEMBL1707235
CHEMBL2087148
CHEMBL2087156
CHEMBL2087157
CHEMBL2354392
6 / 2 / 1 No. 58 No. 11
C00003230 External link 512 Centaurepensin
/ Chlorohyssopifolin A
CHEMBL272221
CHEMBL1334114
C027463
5 / 9 / 13 No. 412 No. 38
C00036469 External link 512 20-Hydroxyecdysone-20,22-monoacetonide
/ (+)-20-Hydroxyecdysone-20,22-monoacetonide
CHEMBL2087536
1 / 1 / 0 No. 1315
C00036372 External link 512 Strangulatoside A
/ 1,2-Di-O-(9Z,12,Z,15Z-Octadecatrienoyl)-3-O-(6-amine-6-deoxy-alpha-D-glucosyl)-glycerol
No. 6034

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08183 Multidrug resistance protein 1 drug C00033543 C00036469 1 / 0
Q9UNA4 DNA polymerase iota Enzyme C00033543 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003230 0 / 0
O75496 Geminin Unclassified protein C00033543 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00033543 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003230 2 / 3
P10636 Microtubule-associated protein tau Unclassified protein C00003230 4 / 3
O00167 Eyes absent homolog 2 Enzyme C00033543 0 / 0
O00255 Menin Unclassified protein C00003230 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003230 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00033543 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612244 Inflammatory bowel disease 13; ibd13 P08183
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)