Species

KNApSAcK Entry

Organism name Picris koreana (Kitam.) Vorosch.
Genus Picris
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Picris
Linked NCBI taxonomy ID 122541
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (9)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003363 External link 512 Balchanin
/ Santamarin
/ Santamarine
CHEMBL89311
CHEMBL366059
C016722
3 / 0 / 0 No. 69 No. 38
C00013038 External link 512 Splendolide
/ Magnolialide
/ [3aS-(3aalpha,5abeta,6beta,9bbeta)]-3a,4,5,5a,6,7,8,9b-Octahydro-6-hydroxy-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one
No. 178 No. 38
C00032170 External link 512 Sonchuside A
/ (+)-Sonchuside A
No. 212
C00020548 External link 512 Ixerin F
No. 259 No. 38
C00021685 External link 512 11beta,13-Dihydroglucozaluzanin C
No. 259 No. 38
C00020817 External link 512 Austricin
/ Desacetylmatricarin
/ 8-Deacetylmatricarin
CHEMBL1325998
CHEMBL1476276
CHEMBL1618787
CHEMBL1623213
CHEMBL1625152
C089156
No. 298 No. 38
C00003248 External link 512 Leucodin
/ Desacetoxymatricarin
CHEMBL517040
CHEMBL1322934
CHEMBL1741501
C476809
12 / 7 / 10 No. 298 No. 38
C00029376 External link 512 11beta,13-Dihydrolactucin
No. 298 No. 38
C00020830 External link 512 Dehydroleucodin
/ Lidbeckialactone
/ 11,13-Dehydroleucodin
CHEMBL441260
CHEMBL189829
C079949
4 / 2 / 2 No. 596 No. 38

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003363 C00020830 0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00003363 C00020830 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00003363 C00020830 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003248 1 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00003248 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00003248 0 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00020830 2 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003248 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003248 2 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003248 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00003248 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003248 0 / 0
O00255 Menin Unclassified protein C00003248 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003248 1 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003248 0 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003248 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (12)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)