Penicillium cyclopium

• Index
• Plant Species
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Penicillium cyclopium
Genus	Penicillium
Family	Trichocomaceae
Kingdom	Fungi

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Penicillium cyclopium
Linked NCBI taxonomy ID	60167
Linked level	species

Family

Family in NCBI taxonomy	Aspergillaceae
ID	1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Fungi
ID	4751

Plant class

Plant class
ID

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00000487	Orsellic acid / Orsellinic acid / 2,4-Dihydroxy-6-methylbenzoic acid / 4,6-Dihydroxy-2-methylbenzoic acid	CHEMBL457583		2 / 0 / 1		No. 2138
C00024000	Mycoin / Patulin / Clavitin / Tercinin / Leucopin / Clavicin / Expansion / Penicidin / Claviformin / 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one	CHEMBL294018	D010365	21 / 26 / 48	23 / 2	No. 7818
C00024006	Penicillic acid / 3-Methoxy-5-methyl-4-oxo-2,5-hexadienoic acid		D010398			No. 8864

Human Protein / Gene in interactions

23 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00000487	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00024000	7 / 37
Q16637	Survival motor neuron protein	Unclassified protein	C00024000	4 / 1
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00024000	0 / 0
P10828	Thyroid hormone receptor beta	NR1A2	C00024000	3 / 1
P19793	Retinoic acid receptor RXR-alpha	NR2B1	C00024000	0 / 0
P06493	Cyclin-dependent kinase 1	Cdc2	C00024000	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00024000	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00024000	0 / 0
P23528	Cofilin-1	Unclassified protein	C00024000	0 / 0
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00024000	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00024000	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00024000	0 / 1
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00024000	5 / 3
Q96RI1	Bile acid receptor	NR1H4	C00024000	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00024000	0 / 0
P03372	Estrogen receptor	NR3A1	C00024000	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00000487	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00024000	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00024000	4 / 3
P05412	Transcription factor AP-1	Transcription Factor	C00024000	0 / 0
P35869	Aryl hydrocarbon receptor	Transcription Factor	C00024000	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00024000	0 / 0

23 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
467	ATF3	activating transcription factor 3	C00024000
10018	BCL2L11, BAM, BIM, BOD	BCL2-like 11 (apoptosis facilitator)	C00024000
637	BID, FP497	BH3 interacting domain death agonist	C00024000
847	CAT	catalase (EC:1.11.1.6)	C00024000
9076	CLDN1, CLD1, ILVASC, SEMP1	claudin 1	C00024000
1365	CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1	claudin 3	C00024000
1364	CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R	claudin 4	C00024000
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00024000
3458	IFNG, IFG, IFI	interferon, gamma	C00024000
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00024000
3596	IL13, IL-13, P600	interleukin 13	C00024000
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00024000
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00024000
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00024000
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00024000
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00024000
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00024000
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00024000
23645	PPP1R15A, GADD34	protein phosphatase 1, regulatory subunit 15A	C00024000
6647	SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer	superoxide dismutase 1, soluble (EC:1.15.1.1)	C00024000
7082	TJP1, ZO-1	tight junction protein 1	C00024000
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00024000
7494	XBP1, TREB5, XBP-1, XBP2	X-box binding protein 1	C00024000

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions