| Organism name | Eudistoma sp. | 
|---|---|
| Genus | Eudistoma | 
| Family | Clavelinidae | 
| Kingdom | Animalia | 
| Linked NCBI taxonomy name | Eudistoma | 
|---|---|
| Linked NCBI taxonomy ID | 286195 | 
| Linked level | genus | 
| Family in NCBI taxonomy | Polycitoridae | 
|---|---|
| ID | 260822 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Metazoa | 
|---|---|
| ID | 33208 | 
| Plant class | |
|---|---|
| ID | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00029586   | 7beta-Hydroperoxycholesterol / 7beta-Hydroperoxycholest-5-en-3beta-ol | No. 53 | No. 11 |   | ||||
| C00046307   | Pibocin B / (-)-Pibocin B | CHEMBL491189 | No. 803 |   | ||||
| C00027035   | Pibocin A / 2-Bromofestuclavine | No. 803 |   | |||||
| C00026960   | Pibocin A | No. 803 |   | |||||
| C00017791   | K 252c / SD 1825 / Antibiotic K 252c | CHEMBL16958 | 54 / 11 / 18 | No. 1236 |   | |||
| C00048705   | Eudistomin Y7 | CHEMBL2048340 | No. 1466 |   | ||||
| C00048703   | Eudistomin Y5 | CHEMBL2048339 | No. 1466 |   | ||||
| C00048704   | Eudistomin Y6 | CHEMBL255883 | No. 1466 |   | ||||
| C00048702   | Eudistomin Y4 | CHEMBL403175 | No. 1466 |   | ||||
| C00048701   | Eudistomin Y3 | CHEMBL2048338 | No. 1466 |   | ||||
| C00048699   | Eudistomin Y1 | CHEMBL403176 | No. 1466 |   | ||||
| C00048700   | Eudistomin Y2 | CHEMBL2048337 | No. 1466 |   | ||||
| C00000520   | Segoline A | No. 2884 |   | |||||
| C00000521   | Segoline B | No. 2884 |   | |||||
| C00000522   | Isosegoline A | No. 2884 |   | |||||
| C00026761   | Eudistomin X / (-)-Eudistomin X | CHEMBL495660 | No. 4262 |   | ||||
| C00026760   | Eudistomin W / (-)-Eudistomin W | CHEMBL442853 | No. 4262 |   | ||||
| C00049320   | Trypargimine | No. 5810 |   | |||||
| C00049071   | 1-Carboxytrypargine | No. 6655 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q15759 | Mitogen-activated protein kinase 11 | p38 | C00017791 | 0 / 0 | 
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00017791 | 0 / 0 | 
| P17252 | Protein kinase C alpha type | Alpha | C00017791 | 0 / 0 | 
| O14757 | Serine/threonine-protein kinase Chk1 | Chk1 | C00017791 | 0 / 0 | 
| P80192 | Mitogen-activated protein kinase kinase kinase 9 | TKL dual-specificity kinase MLK | C00017791 | 0 / 0 | 
| P23443 | Ribosomal protein S6 kinase beta-1 | p70 | C00017791 | 0 / 0 | 
| P11802 | Cyclin-dependent kinase 4 | CMGC serine/threonine protein kinase family | C00017791 | 1 / 3 | 
| P24385 | G1/S-specific cyclin-D1 | Other cytosolic protein | C00017791 | 1 / 8 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00017791 | 0 / 0 | 
| O75582 | Ribosomal protein S6 kinase alpha-5 | CAMK serine/threonine protein kinase MSKB subfamily | C00017791 | 0 / 0 | 
| P17538 | Chymotrypsinogen B | S1A | C00017791 | 0 / 0 | 
| Q16584 | Mitogen-activated protein kinase kinase kinase 11 | TKL dual-specificity kinase MLK | C00017791 | 0 / 0 | 
| P08151 | Zinc finger protein GLI1 | Unclassified protein | C00017791 | 0 / 0 | 
| P10070 | Zinc finger protein GLI2 | Unclassified protein | C00017791 | 1 / 1 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00017791 | 2 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00017791 | 0 / 0 | 
| O15264 | Mitogen-activated protein kinase 13 | p38 | C00017791 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00017791 | 0 / 0 | 
| P49137 | MAP kinase-activated protein kinase 2 | CAMK serine/threonine protein kinase MAPKAPK | C00017791 | 0 / 0 | 
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00017791 | 0 / 0 | 
| P45983 | Mitogen-activated protein kinase 8 | Jnk | C00017791 | 0 / 0 | 
| Q8IW41 | MAP kinase-activated protein kinase 5 | CAMK serine/threonine protein kinase MAPKAPK | C00017791 | 0 / 0 | 
| Q02880 | DNA topoisomerase 2-beta | Isomerase | C00017791 | 0 / 0 | 
| P31749 | RAC-alpha serine/threonine-protein kinase | Akt | C00017791 | 4 / 1 | 
| Q15118 | [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial | Pdhk | C00017791 | 0 / 0 | 
| O00141 | Serine/threonine-protein kinase Sgk1 | AGC serine/threonine protein kinase SGK subfamily | C00017791 | 0 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00017791 | 0 / 0 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00017791 | 0 / 1 | 
| P52333 | Tyrosine-protein kinase JAK3 | Jakb | C00017791 | 1 / 1 | 
| P53778 | Mitogen-activated protein kinase 12 | p38 | C00017791 | 0 / 0 | 
| Q05513 | Protein kinase C zeta type | Iota | C00017791 | 0 / 0 | 
| Q04759 | Protein kinase C theta type | Delta | C00017791 | 0 / 1 | 
| Q02156 | Protein kinase C epsilon type | Eta | C00017791 | 0 / 0 | 
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00017791 | 0 / 0 | 
| Q05655 | Protein kinase C delta type | Delta | C00017791 | 0 / 0 | 
| P05129 | Protein kinase C gamma type | Alpha | C00017791 | 1 / 1 | 
| P05771 | Protein kinase C beta type | Alpha | C00017791 | 0 / 0 | 
| P24723 | Protein kinase C eta type | Eta | C00017791 | 1 / 0 | 
| P41743 | Protein kinase C iota type | Iota | C00017791 | 0 / 0 | 
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00017791 | 0 / 0 | 
| Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | Camk2 | C00017791 | 0 / 0 | 
| Q13555 | Calcium/calmodulin-dependent protein kinase type II subunit gamma | Camk2 | C00017791 | 0 / 0 | 
| Q13554 | Calcium/calmodulin-dependent protein kinase type II subunit beta | Camk2 | C00017791 | 0 / 0 | 
| Q13557 | Calcium/calmodulin-dependent protein kinase type II subunit delta | Camk2 | C00017791 | 0 / 0 | 
| P24864 | G1/S-specific cyclin-E1 | Other cytosolic protein | C00017791 | 0 / 2 | 
| P24941 | Cyclin-dependent kinase 2 | Cdc2 | C00017791 | 0 / 0 | 
| O96020 | G1/S-specific cyclin-E2 | Other cytosolic protein | C00017791 | 0 / 2 | 
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00017791 | 0 / 0 | 
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00017791 | 0 / 0 | 
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00017791 | 0 / 0 | 
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00017791 | 0 / 0 | 
| P22694 | cAMP-dependent protein kinase catalytic subunit beta | Pka | C00017791 | 0 / 0 | 
| P17612 | cAMP-dependent protein kinase catalytic subunit alpha | Pka | C00017791 | 0 / 0 | 
| P22612 | cAMP-dependent protein kinase catalytic subunit gamma | Pka | C00017791 | 0 / 0 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #114480 | Breast cancer | P31749 | 
| #114500 | Colorectal cancer; crc | P31749 P84022 | 
| #615109 | Cowden syndrome 6; cws6 | P31749 | 
| #610829 | Holoprosencephaly 9; hpe9 | P10070 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #609048 | Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 | P11802 | 
| #254500 | Myeloma, multiple | P24385 | 
| #176920 | Proteus syndrome | P31749 | 
| #600802 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative | P52333 | 
| #605361 | Spinocerebellar ataxia 14; sca14 | P05129 | 
| #601367 | Stroke, ischemic | P24723 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00018 | Gastric cancer | O96020
                            (related) P24864 (related) | 
| H00055 | Laryngeal cancer | O96020
                            (related) P24385 (related) P24385 (marker) P24864 (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | P05129
                            (related) | 
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00267 | Holoprosencephaly (HPE) | P10070
                            (related) | 
| H00030 | Cervical cancer | P11802
                            (related) | 
| H00038 | Malignant melanoma | P11802
                            (related) | 
| H00042 | Glioma | P11802
                            (related) | 
| H00006 | Hairy-cell leukemia | P24385
                            (related) | 
| H00010 | Multiple myeloma | P24385
                            (related) | 
| H00016 | Oral cancer | P24385
                            (related) P24385 (marker) | 
| H00017 | Esophageal cancer | P24385
                            (related) | 
| H00031 | Breast cancer | P24385
                            (related) | 
| H00559 | von Hippel-Lindau syndrome | P24385
                            (related) | 
| H00047 | Gallbladder cancer | P24385
                            (marker) | 
| H00539 | PTEN hamartoma tumor syndrome (PHTS) | P31749
                            (related) | 
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) | P52333
                            (related) | 
| H00408 | Type I diabetes mellitus | Q04759
                            (related) |