Species

KNApSAcK Entry

Organism name Eudistoma sp.
Genus Eudistoma
Family Clavelinidae
Kingdom Animalia

NCBI taxonomy

Entry

Linked NCBI taxonomy name Eudistoma
Linked NCBI taxonomy ID 286195
Linked level genus

Family

Family in NCBI taxonomy Polycitoridae
ID 260822

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Metazoa
ID 33208

Plant class

Plant class
ID

Metabolite list (19)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00029586 External link 512 7beta-Hydroperoxycholesterol
/ 7beta-Hydroperoxycholest-5-en-3beta-ol
No. 53 No. 11
C00046307 External link 512 Pibocin B
/ (-)-Pibocin B
CHEMBL491189
No. 803
C00027035 External link 512 Pibocin A
/ 2-Bromofestuclavine
No. 803
C00026960 External link 512 Pibocin A
No. 803
C00017791 External link 512 K 252c
/ SD 1825
/ Antibiotic K 252c
CHEMBL16958
54 / 11 / 18 No. 1236
C00048705 External link 512 Eudistomin Y7
CHEMBL2048340
No. 1466
C00048703 External link 512 Eudistomin Y5
CHEMBL2048339
No. 1466
C00048704 External link 512 Eudistomin Y6
CHEMBL255883
No. 1466
C00048702 External link 512 Eudistomin Y4
CHEMBL403175
No. 1466
C00048701 External link 512 Eudistomin Y3
CHEMBL2048338
No. 1466
C00048699 External link 512 Eudistomin Y1
CHEMBL403176
No. 1466
C00048700 External link 512 Eudistomin Y2
CHEMBL2048337
No. 1466
C00000520 External link 512 Segoline A
No. 2884
C00000521 External link 512 Segoline B
No. 2884
C00000522 External link 512 Isosegoline A
No. 2884
C00026761 External link 512 Eudistomin X
/ (-)-Eudistomin X
CHEMBL495660
No. 4262
C00026760 External link 512 Eudistomin W
/ (-)-Eudistomin W
CHEMBL442853
No. 4262
C00049320 External link 512 Trypargimine
No. 5810
C00049071 External link 512 1-Carboxytrypargine
No. 6655

Human Protein / Gene in interactions

54 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q15759 Mitogen-activated protein kinase 11 p38 C00017791 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00017791 0 / 0
P17252 Protein kinase C alpha type Alpha C00017791 0 / 0
O14757 Serine/threonine-protein kinase Chk1 Chk1 C00017791 0 / 0
P80192 Mitogen-activated protein kinase kinase kinase 9 TKL dual-specificity kinase MLK C00017791 0 / 0
P23443 Ribosomal protein S6 kinase beta-1 p70 C00017791 0 / 0
P11802 Cyclin-dependent kinase 4 CMGC serine/threonine protein kinase family C00017791 1 / 3
P24385 G1/S-specific cyclin-D1 Other cytosolic protein C00017791 1 / 8
P11387 DNA topoisomerase 1 Isomerase C00017791 0 / 0
O75582 Ribosomal protein S6 kinase alpha-5 CAMK serine/threonine protein kinase MSKB subfamily C00017791 0 / 0
P17538 Chymotrypsinogen B S1A C00017791 0 / 0
Q16584 Mitogen-activated protein kinase kinase kinase 11 TKL dual-specificity kinase MLK C00017791 0 / 0
P08151 Zinc finger protein GLI1 Unclassified protein C00017791 0 / 0
P10070 Zinc finger protein GLI2 Unclassified protein C00017791 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00017791 2 / 0
P49841 Glycogen synthase kinase-3 beta Gsk C00017791 0 / 0
O15264 Mitogen-activated protein kinase 13 p38 C00017791 0 / 0
P11021 78 kDa glucose-regulated protein Unclassified protein C00017791 0 / 0
P49137 MAP kinase-activated protein kinase 2 CAMK serine/threonine protein kinase MAPKAPK C00017791 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00017791 0 / 0
P45983 Mitogen-activated protein kinase 8 Jnk C00017791 0 / 0
Q8IW41 MAP kinase-activated protein kinase 5 CAMK serine/threonine protein kinase MAPKAPK C00017791 0 / 0
Q02880 DNA topoisomerase 2-beta Isomerase C00017791 0 / 0
P31749 RAC-alpha serine/threonine-protein kinase Akt C00017791 4 / 1
Q15118 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial Pdhk C00017791 0 / 0
O00141 Serine/threonine-protein kinase Sgk1 AGC serine/threonine protein kinase SGK subfamily C00017791 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00017791 0 / 0
P06239 Tyrosine-protein kinase Lck Src C00017791 0 / 1
P52333 Tyrosine-protein kinase JAK3 Jakb C00017791 1 / 1
P53778 Mitogen-activated protein kinase 12 p38 C00017791 0 / 0
Q05513 Protein kinase C zeta type Iota C00017791 0 / 0
Q04759 Protein kinase C theta type Delta C00017791 0 / 1
Q02156 Protein kinase C epsilon type Eta C00017791 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00017791 0 / 0
Q05655 Protein kinase C delta type Delta C00017791 0 / 0
P05129 Protein kinase C gamma type Alpha C00017791 1 / 1
P05771 Protein kinase C beta type Alpha C00017791 0 / 0
P24723 Protein kinase C eta type Eta C00017791 1 / 0
P41743 Protein kinase C iota type Iota C00017791 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00017791 0 / 0
Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha Camk2 C00017791 0 / 0
Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma Camk2 C00017791 0 / 0
Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta Camk2 C00017791 0 / 0
Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta Camk2 C00017791 0 / 0
P24864 G1/S-specific cyclin-E1 Other cytosolic protein C00017791 0 / 2
P24941 Cyclin-dependent kinase 2 Cdc2 C00017791 0 / 0
O96020 G1/S-specific cyclin-E2 Other cytosolic protein C00017791 0 / 2
O95067 G2/mitotic-specific cyclin-B2 Other cytosolic protein C00017791 0 / 0
P14635 G2/mitotic-specific cyclin-B1 Other cytosolic protein C00017791 0 / 0
P06493 Cyclin-dependent kinase 1 Cdc2 C00017791 0 / 0
Q8WWL7 G2/mitotic-specific cyclin-B3 Other cytosolic protein C00017791 0 / 0
P22694 cAMP-dependent protein kinase catalytic subunit beta Pka C00017791 0 / 0
P17612 cAMP-dependent protein kinase catalytic subunit alpha Pka C00017791 0 / 0
P22612 cAMP-dependent protein kinase catalytic subunit gamma Pka C00017791 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#114480 Breast cancer P31749
#114500 Colorectal cancer; crc P31749
P84022
#615109 Cowden syndrome 6; cws6 P31749
#610829 Holoprosencephaly 9; hpe9 P10070
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#609048 Melanoma, cutaneous malignant, susceptibility to, 3; cmm3 P11802
#254500 Myeloma, multiple P24385
#176920 Proteus syndrome P31749
#600802 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-negative P52333
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723

KEGG DISEASE (18)

KEGG name UniProt
H00018 Gastric cancer O96020 (related)
P24864 (related)
H00055 Laryngeal cancer O96020 (related)
P24385 (related)
P24385 (marker)
P24864 (related)
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00267 Holoprosencephaly (HPE) P10070 (related)
H00030 Cervical cancer P11802 (related)
H00038 Malignant melanoma P11802 (related)
H00042 Glioma P11802 (related)
H00006 Hairy-cell leukemia P24385 (related)
H00010 Multiple myeloma P24385 (related)
H00016 Oral cancer P24385 (related)
P24385 (marker)
H00017 Esophageal cancer P24385 (related)
H00031 Breast cancer P24385 (related)
H00559 von Hippel-Lindau syndrome P24385 (related)
H00047 Gallbladder cancer P24385 (marker)
H00539 PTEN hamartoma tumor syndrome (PHTS) P31749 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P52333 (related)
H00408 Type I diabetes mellitus Q04759 (related)