Species

KNApSAcK Entry

Organism name Acanthopanax senticosus
Genus Acanthopanax
Family Araliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Eleutherococcus senticosus
Linked NCBI taxonomy ID 82096
Linked level species

Family

Family in NCBI taxonomy Araliaceae
ID 4050

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (25)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00041912 External link 512 Tauroside H1
No. 4 No. 51
C00035264 External link 512 Ciwujianoside C4
/ (-)-Ciwujianoside C4
No. 4 No. 51
C00029690 External link 512 Anhuienside C
No. 4 No. 51
C00035263 External link 512 Ciwujianoside C3
/ (-)-Ciwujianoside C3
CHEMBL506188
CHEMBL1171250
3 / 0 / 3 No. 4 No. 51
C00041446 External link 512 Ciwujianoside A2
No. 4 No. 51
C00035262 External link 512 Ciwujianoside C2
No. 4 No. 51
C00030169 External link 512 Eleutheroside L
No. 4 No. 51
C00041305 External link 512 Acanthopanaxoside B
/ (-)-Acanthopanaxoside B
No. 4 No. 51
C00030461 External link 512 Hederasaponin B
CHEMBL506829
CHEMBL506880
3 / 0 / 3 No. 4 No. 51
C00041304 External link 512 Acanthopanaxoside A
/ (+)-Acanthopanaxoside A
No. 4 No. 51
C00035261 External link 512 Yemuoside YM14
/ Ciwujianoside C1
C077203
No. 4 No. 51
C00035260 External link 512 Ciwujianoside B
C062410
No. 4 No. 51
C00035266 External link 512 Ciwujianoside D2
/ (+)-Ciwujianoside D2
No. 4 No. 51
C00031381 External link 512 Silphioside G
/ (+)-Silphioside G
CHEMBL1095348
CHEMBL1725204
C098580
8 / 6 / 5 No. 9 No. 51
C00030509 External link 512 Ilexoside XLVIII
CHEMBL454262
1 / 0 / 0 No. 9 No. 51
C00041306 External link 512 Acanthopanaxoside C
/ (-)-Acanthopanaxoside C
No. 9 No. 51
C00041863 External link 512 Sessiloside
CHEMBL447549
1 / 0 / 0 No. 9 No. 51
C00029616 External link 512 Acanthopanaxoside E
/ (-)-Acanthopanaxoside E
No. 9 No. 51
C00030469 External link 512 Hemsgiganoside B
No. 9 No. 51
C00032813 External link 512 Chiisanoside
CHEMBL507957
1 / 0 / 0 No. 9 No. 51
C00030460 External link 512 Hederagenin 3-O-beta-D-glucuronopyranoside 6'-O-methyl ester
No. 50 No. 51
C00030011 External link 512 Copteroside B
/ (+)-Copteroside B
/ Caryocaroside II-5
/ (+)-Caryocaroside II-5
CHEMBL450705
No. 50 No. 51
C00003538 External link 512 Silphioside F
/ Calenduloside E
/ (+)-Silphioside F
/ (+)-Calenduloside E
/ Oleanoic acid 3-O-glucuronide
CHEMBL446866
CHEMBL1974914
No. 50 No. 51
C00030168 External link 512 Eleutheroside E
CHEMBL446836
CHEMBL505393
2 / 2 / 2 No. 152
C00030167 External link 512 Eleutheroside B
CHEMBL250872
C028305
1 / 0 / 0 0 / 1 No. 678 No. 6

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P16233 Pancreatic triacylglycerol lipase Hydrolase C00030461 C00032813 C00035263 C00041863 0 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00030167 C00030461 C00035263 0 / 0
O75496 Geminin Unclassified protein C00030168 C00031381 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00030461 C00035263 0 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00031381 2 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00030168 2 / 2
P11473 Vitamin D3 receptor NR1I1 C00031381 2 / 3
P35610 Sterol O-acyltransferase 1 Enzyme C00030509 0 / 0
Q99700 Ataxin-2 Unclassified protein C00031381 1 / 1
Q9Y253 DNA polymerase eta Enzyme C00031381 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00031381 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00031381 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00031381 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (10)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001862 Bone Resorption C00030167