KEGG   COMPOUND: C00064
Entry
C00064                      Compound                               
Name
L-Glutamine;
L-2-Aminoglutaramic acid
Formula
C5H10N2O3
Exact mass
146.0691
Mol weight
146.14
Structure
Remark
Same as: D00015
Reaction
R00021 R00093 R00114 R00253 R00256 R00257 R00573 R00575
R00576 R00577 R00578 R00579 R00768 R00986 R01072 R01149
R01231 R01375 R01716 R02576 R02781 R02895 R03652 R03905
R04011 R04212 R04463 R04558 R05224 R05225 R05815 R07456
R08244 R08855 R08890 R08891 R08956 R09195 R09598 R09599
R10089 R11515 R11627 R11941 R12352 R12478 R12507 R12590
R12939 R13353 R13355
Pathway
map00220  Arginine biosynthesis
map00230  Purine metabolism
map00240  Pyrimidine metabolism
map00250  Alanine, aspartate and glutamate metabolism
map00470  D-Amino acid metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00750  Vitamin B6 metabolism
map00910  Nitrogen metabolism
map00970  Aminoacyl-tRNA biosynthesis
map01060  Biosynthesis of plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01230  Biosynthesis of amino acids
map01232  Nucleotide metabolism
map01240  Biosynthesis of cofactors
map02010  ABC transporters
map02020  Two-component system
map04724  Glutamatergic synapse
map04727  GABAergic synapse
map04964  Proximal tubule bicarbonate reclamation
map04974  Protein digestion and absorption
map04978  Mineral absorption
map05230  Central carbon metabolism in cancer
Module
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
M00916  Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P
M00978  Ornithine-ammonia cycle
Enzyme
1.4.1.13        1.4.1.14        1.4.7.1         2.3.1.14        
2.3.1.68        2.3.2.1         2.3.2.14        2.4.2.14        
2.6.1.15        2.6.1.16        2.6.1.50        2.6.1.64        
2.6.1.85        2.6.1.86        2.6.1.100       2.6.1.101       
2.6.1.117       2.6.1.123       2.7.3.13        3.5.1.2         
3.5.1.38        3.5.1.133       4.1.3.27        4.3.2.10        
4.3.3.6         4.3.3.9         5.1.1.10        6.1.1.18        
6.3.1.2         6.3.4.2         6.3.5.1         6.3.5.2         
6.3.5.3         6.3.5.4         6.3.5.5         6.3.5.6         
6.3.5.7         6.3.5.9         6.3.5.10        6.3.5.11        
6.3.5.12        6.3.5.13        6.3.5.-
 » show all
Brite
Compounds with biological roles [BR:br08001]
 Peptides
  Amino acids
   Common amino acids
    C00064  Glutamine (Gln)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
   A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
    A16AA Amino acids and derivatives
     A16AA03 Glutamine
      D00015  Glutamine (USP) <US>
USP drug classification [BR:br08302]
 Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
  Glutamine
   D00015  Glutamine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  23  Digestive organ agents
   232  Peptic ulcer agents
    2322  Glutamines
     D00015  Glutamine (USP); L-Glutamine (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   L-Glutamine
    D00015  Glutamine (USP)
Drug groups [BR:br08330]
 Gastrointestinal agent
  DG01975  Agents for peptic ulcer
   DG02008  Gastric mucosal protectant
    D00015  Glutamine
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00015  L-Glutamine
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D00015
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00015
Other DBs
CAS: 56-85-9
PubChem: 3364
ChEBI: 18050
KNApSAcK: C00001359
PDB-CCD: GLN[PDBj]
NIKKAJI: J9.170G
KCF data

ATOM        10
            1   C1c C    23.8378  -17.4606
            2   C1b C    25.0254  -16.7178
            3   C6a C    22.6035  -16.7995
            4   N1a N    23.8787  -18.8587
            5   C1b C    26.2597  -17.3787
            6   O6a O    21.4451  -17.5952
            7   O6a O    22.6209  -15.4015
            8   C5a C    27.4472  -16.6416
            9   N1a N    28.6814  -17.3027
            10  O5a O    27.4704  -15.2435
BOND        9
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 2
            7     5   8 1
            8     8   9 1
            9     8  10 2

» Japanese version

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Pathway (28)   
   KEGG PATHWAY (24)   
   KEGG MODULE (4)   
Drug (1)   
   KEGG DRUG (1)   
Chemical substance (45)   
   PubChem (1)   
   ChEBI (1)   
   HMDB (1)   
   KNApSAcK (1)   
   MASSBANK (39)   
   NIKKAJI (1)   
   PDB-CCD (1)   
Chemical reaction (93)   
   KEGG ENZYME (42)   
   KEGG REACTION (51)   
Gene (238578)   
   KEGG GENES (238578)   
All databases (238745)   

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