HEADER TRANSLATION 18-JUN-15 3JAP
TITLE STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED
TITLE 2 CONFORMATION
COMPND MOL_ID: 1;
COMPND 2 MOLECULE: MET-TRNAI (U31:A39 VARIANT);
COMPND 3 CHAIN: 1;
COMPND 4 ENGINEERED: YES;
COMPND 5 MOL_ID: 2;
COMPND 6 MOLECULE: 18S RRNA;
COMPND 7 CHAIN: 2;
COMPND 8 MOL_ID: 3;
COMPND 9 MOLECULE: MRNA;
COMPND 10 CHAIN: 3;
COMPND 11 ENGINEERED: YES;
COMPND 12 MOL_ID: 4;
COMPND 13 MOLECULE: US2;
COMPND 14 CHAIN: A;
COMPND 15 MOL_ID: 5;
COMPND 16 MOLECULE: ES1;
COMPND 17 CHAIN: B;
COMPND 18 MOL_ID: 6;
COMPND 19 MOLECULE: US5;
COMPND 20 CHAIN: C;
COMPND 21 MOL_ID: 7;
COMPND 22 MOLECULE: US3;
COMPND 23 CHAIN: D;
COMPND 24 MOL_ID: 8;
COMPND 25 MOLECULE: ES4;
COMPND 26 CHAIN: E;
COMPND 27 MOL_ID: 9;
COMPND 28 MOLECULE: US7;
COMPND 29 CHAIN: F;
COMPND 30 MOL_ID: 10;
COMPND 31 MOLECULE: ES6;
COMPND 32 CHAIN: G;
COMPND 33 MOL_ID: 11;
COMPND 34 MOLECULE: ES7;
COMPND 35 CHAIN: H;
COMPND 36 MOL_ID: 12;
COMPND 37 MOLECULE: ES8;
COMPND 38 CHAIN: I;
COMPND 39 MOL_ID: 13;
COMPND 40 MOLECULE: US4;
COMPND 41 CHAIN: J;
COMPND 42 MOL_ID: 14;
COMPND 43 MOLECULE: ES10;
COMPND 44 CHAIN: K;
COMPND 45 MOL_ID: 15;
COMPND 46 MOLECULE: US17;
COMPND 47 CHAIN: L;
COMPND 48 MOL_ID: 16;
COMPND 49 MOLECULE: ES12;
COMPND 50 CHAIN: M;
COMPND 51 MOL_ID: 17;
COMPND 52 MOLECULE: US15;
COMPND 53 CHAIN: N;
COMPND 54 MOL_ID: 18;
COMPND 55 MOLECULE: US11;
COMPND 56 CHAIN: O;
COMPND 57 MOL_ID: 19;
COMPND 58 MOLECULE: US19;
COMPND 59 CHAIN: P;
COMPND 60 MOL_ID: 20;
COMPND 61 MOLECULE: US9;
COMPND 62 CHAIN: Q;
COMPND 63 MOL_ID: 21;
COMPND 64 MOLECULE: ES17;
COMPND 65 CHAIN: R;
COMPND 66 MOL_ID: 22;
COMPND 67 MOLECULE: US13;
COMPND 68 CHAIN: S;
COMPND 69 MOL_ID: 23;
COMPND 70 MOLECULE: ES19;
COMPND 71 CHAIN: T;
COMPND 72 MOL_ID: 24;
COMPND 73 MOLECULE: US10;
COMPND 74 CHAIN: U;
COMPND 75 MOL_ID: 25;
COMPND 76 MOLECULE: ES21;
COMPND 77 CHAIN: V;
COMPND 78 MOL_ID: 26;
COMPND 79 MOLECULE: US8;
COMPND 80 CHAIN: W;
COMPND 81 MOL_ID: 27;
COMPND 82 MOLECULE: US12;
COMPND 83 CHAIN: X;
COMPND 84 MOL_ID: 28;
COMPND 85 MOLECULE: ES24;
COMPND 86 CHAIN: Y;
COMPND 87 MOL_ID: 29;
COMPND 88 MOLECULE: ES25;
COMPND 89 CHAIN: Z;
COMPND 90 MOL_ID: 30;
COMPND 91 MOLECULE: ES26;
COMPND 92 CHAIN: a;
COMPND 93 MOL_ID: 31;
COMPND 94 MOLECULE: ES27;
COMPND 95 CHAIN: b;
COMPND 96 MOL_ID: 32;
COMPND 97 MOLECULE: ES28;
COMPND 98 CHAIN: c;
COMPND 99 MOL_ID: 33;
COMPND 100 MOLECULE: US14;
COMPND 101 CHAIN: d;
COMPND 102 MOL_ID: 34;
COMPND 103 MOLECULE: ES30;
COMPND 104 CHAIN: e;
COMPND 105 MOL_ID: 35;
COMPND 106 MOLECULE: ES31;
COMPND 107 CHAIN: f;
COMPND 108 MOL_ID: 36;
COMPND 109 MOLECULE: RACK1;
COMPND 110 CHAIN: g;
COMPND 111 MOL_ID: 37;
COMPND 112 MOLECULE: EL41;
COMPND 113 CHAIN: h;
COMPND 114 MOL_ID: 38;
COMPND 115 MOLECULE: EIF1A;
COMPND 116 CHAIN: i;
COMPND 117 ENGINEERED: YES;
COMPND 118 MOL_ID: 39;
COMPND 119 MOLECULE: EIF2 ALPHA;
COMPND 120 CHAIN: j;
COMPND 121 ENGINEERED: YES;
COMPND 122 MOL_ID: 40;
COMPND 123 MOLECULE: EIF2 GAMMA;
COMPND 124 CHAIN: k;
COMPND 125 ENGINEERED: YES;
COMPND 126 MOL_ID: 41;
COMPND 127 MOLECULE: EIF2 BETA;
COMPND 128 CHAIN: l;
COMPND 129 ENGINEERED: YES;
COMPND 130 MOL_ID: 42;
COMPND 131 MOLECULE: EIF1;
COMPND 132 CHAIN: m;
COMPND 133 ENGINEERED: YES;
COMPND 134 MOL_ID: 43;
COMPND 135 MOLECULE: EIF3A;
COMPND 136 CHAIN: o;
COMPND 137 ENGINEERED: YES;
COMPND 138 MOL_ID: 44;
COMPND 139 MOLECULE: EIF3C;
COMPND 140 CHAIN: p;
COMPND 141 ENGINEERED: YES;
COMPND 142 MOL_ID: 45;
COMPND 143 MOLECULE: EIF3I;
COMPND 144 CHAIN: q;
COMPND 145 ENGINEERED: YES;
COMPND 146 MOL_ID: 46;
COMPND 147 MOLECULE: EIF3B;
COMPND 148 CHAIN: r;
COMPND 149 ENGINEERED: YES;
COMPND 150 MOL_ID: 47;
COMPND 151 MOLECULE: EIF3G;
COMPND 152 CHAIN: s;
COMPND 153 ENGINEERED: YES
SOURCE MOL_ID: 1;
SOURCE 2 SYNTHETIC: YES;
SOURCE 3 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 4 ORGANISM_TAXID: 28985;
SOURCE 5 MOL_ID: 2;
SOURCE 6 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 7 ORGANISM_TAXID: 28985;
SOURCE 8 MOL_ID: 3;
SOURCE 9 SYNTHETIC: YES;
SOURCE 10 ORGANISM_SCIENTIFIC: SYNTHETIC CONSTRUCT;
SOURCE 11 ORGANISM_TAXID: 32630;
SOURCE 12 MOL_ID: 4;
SOURCE 13 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 14 ORGANISM_TAXID: 28985;
SOURCE 15 MOL_ID: 5;
SOURCE 16 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 17 ORGANISM_TAXID: 28985;
SOURCE 18 MOL_ID: 6;
SOURCE 19 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 20 ORGANISM_TAXID: 28985;
SOURCE 21 MOL_ID: 7;
SOURCE 22 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 23 ORGANISM_TAXID: 28985;
SOURCE 24 MOL_ID: 8;
SOURCE 25 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 26 ORGANISM_TAXID: 28985;
SOURCE 27 MOL_ID: 9;
SOURCE 28 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 29 ORGANISM_TAXID: 28985;
SOURCE 30 MOL_ID: 10;
SOURCE 31 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 32 ORGANISM_TAXID: 28985;
SOURCE 33 MOL_ID: 11;
SOURCE 34 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 35 ORGANISM_TAXID: 28985;
SOURCE 36 MOL_ID: 12;
SOURCE 37 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 38 ORGANISM_TAXID: 28985;
SOURCE 39 MOL_ID: 13;
SOURCE 40 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 41 ORGANISM_TAXID: 28985;
SOURCE 42 MOL_ID: 14;
SOURCE 43 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 44 ORGANISM_TAXID: 28985;
SOURCE 45 MOL_ID: 15;
SOURCE 46 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 47 ORGANISM_TAXID: 28985;
SOURCE 48 MOL_ID: 16;
SOURCE 49 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 50 ORGANISM_TAXID: 28985;
SOURCE 51 MOL_ID: 17;
SOURCE 52 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 53 ORGANISM_TAXID: 28985;
SOURCE 54 MOL_ID: 18;
SOURCE 55 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 56 ORGANISM_TAXID: 28985;
SOURCE 57 MOL_ID: 19;
SOURCE 58 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 59 ORGANISM_TAXID: 28985;
SOURCE 60 MOL_ID: 20;
SOURCE 61 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 62 ORGANISM_TAXID: 28985;
SOURCE 63 MOL_ID: 21;
SOURCE 64 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 65 ORGANISM_TAXID: 28985;
SOURCE 66 MOL_ID: 22;
SOURCE 67 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 68 ORGANISM_TAXID: 28985;
SOURCE 69 MOL_ID: 23;
SOURCE 70 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 71 ORGANISM_TAXID: 28985;
SOURCE 72 MOL_ID: 24;
SOURCE 73 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 74 ORGANISM_TAXID: 28985;
SOURCE 75 MOL_ID: 25;
SOURCE 76 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 77 ORGANISM_TAXID: 28985;
SOURCE 78 MOL_ID: 26;
SOURCE 79 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 80 ORGANISM_TAXID: 28985;
SOURCE 81 MOL_ID: 27;
SOURCE 82 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 83 ORGANISM_TAXID: 28985;
SOURCE 84 MOL_ID: 28;
SOURCE 85 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 86 ORGANISM_TAXID: 28985;
SOURCE 87 MOL_ID: 29;
SOURCE 88 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 89 ORGANISM_TAXID: 28985;
SOURCE 90 MOL_ID: 30;
SOURCE 91 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 92 ORGANISM_TAXID: 28985;
SOURCE 93 MOL_ID: 31;
SOURCE 94 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 95 ORGANISM_TAXID: 28985;
SOURCE 96 MOL_ID: 32;
SOURCE 97 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 98 ORGANISM_TAXID: 28985;
SOURCE 99 MOL_ID: 33;
SOURCE 100 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 101 ORGANISM_TAXID: 28985;
SOURCE 102 MOL_ID: 34;
SOURCE 103 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 104 ORGANISM_TAXID: 28985;
SOURCE 105 MOL_ID: 35;
SOURCE 106 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 107 ORGANISM_TAXID: 28985;
SOURCE 108 MOL_ID: 36;
SOURCE 109 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 110 ORGANISM_TAXID: 28985;
SOURCE 111 MOL_ID: 37;
SOURCE 112 ORGANISM_SCIENTIFIC: KLUYVEROMYCES LACTIS;
SOURCE 113 ORGANISM_TAXID: 28985;
SOURCE 114 MOL_ID: 38;
SOURCE 115 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 116 ORGANISM_COMMON: YEAST;
SOURCE 117 ORGANISM_TAXID: 4932;
SOURCE 118 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;
SOURCE 119 EXPRESSION_SYSTEM_TAXID: 511693;
SOURCE 120 EXPRESSION_SYSTEM_STRAIN: ROSETTA;
SOURCE 121 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;
SOURCE 122 EXPRESSION_SYSTEM_PLASMID: PTYB2;
SOURCE 123 MOL_ID: 39;
SOURCE 124 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 125 ORGANISM_COMMON: YEAST;
SOURCE 126 ORGANISM_TAXID: 4932;
SOURCE 127 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 128 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 129 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 130 MOL_ID: 40;
SOURCE 131 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 132 ORGANISM_COMMON: YEAST;
SOURCE 133 ORGANISM_TAXID: 4932;
SOURCE 134 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 135 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 136 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 137 MOL_ID: 41;
SOURCE 138 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 139 ORGANISM_COMMON: YEAST;
SOURCE 140 ORGANISM_TAXID: 4932;
SOURCE 141 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 142 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 143 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 144 MOL_ID: 42;
SOURCE 145 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 146 ORGANISM_COMMON: YEAST;
SOURCE 147 ORGANISM_TAXID: 4932;
SOURCE 148 EXPRESSION_SYSTEM: ESCHERICHIA COLI BL21;
SOURCE 149 EXPRESSION_SYSTEM_TAXID: 511693;
SOURCE 150 EXPRESSION_SYSTEM_STRAIN: ROSETTA;
SOURCE 151 EXPRESSION_SYSTEM_VECTOR_TYPE: PLASMID;
SOURCE 152 EXPRESSION_SYSTEM_PLASMID: PTYB2;
SOURCE 153 MOL_ID: 43;
SOURCE 154 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 155 ORGANISM_COMMON: YEAST;
SOURCE 156 ORGANISM_TAXID: 4932;
SOURCE 157 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 158 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 159 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 160 MOL_ID: 44;
SOURCE 161 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 162 ORGANISM_COMMON: YEAST;
SOURCE 163 ORGANISM_TAXID: 4932;
SOURCE 164 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 165 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 166 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 167 MOL_ID: 45;
SOURCE 168 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 169 ORGANISM_COMMON: YEAST;
SOURCE 170 ORGANISM_TAXID: 4932;
SOURCE 171 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 172 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 173 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 174 MOL_ID: 46;
SOURCE 175 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 176 ORGANISM_COMMON: YEAST;
SOURCE 177 ORGANISM_TAXID: 4932;
SOURCE 178 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 179 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 180 EXPRESSION_SYSTEM_TAXID: 4932;
SOURCE 181 MOL_ID: 47;
SOURCE 182 ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE;
SOURCE 183 ORGANISM_COMMON: YEAST;
SOURCE 184 ORGANISM_TAXID: 4932;
SOURCE 185 EXPRESSION_SYSTEM: SACCHAROMYCES CEREVISIAE;
SOURCE 186 EXPRESSION_SYSTEM_COMMON: YEAST;
SOURCE 187 EXPRESSION_SYSTEM_TAXID: 4932
KEYWDS EUKARYOTIC TRANSLATION INITIATION, 48S, SMALL RIBOSOME SUBUNIT, 40S,
KEYWDS 2 43S, TRANSLATION
EXPDTA ELECTRON MICROSCOPY
AUTHOR J.L.LLACER,T.HUSSAIN,V.RAMAKRISHNAN
REVDAT 4 21-FEB-24 3JAP 1 REMARK LINK
REVDAT 3 18-JUL-18 3JAP 1 REMARK
REVDAT 2 02-SEP-15 3JAP 1 JRNL
REVDAT 1 12-AUG-15 3JAP 0
JRNL AUTH J.L.LLACER,T.HUSSAIN,L.MARLER,C.E.AITKEN,A.THAKUR,
JRNL AUTH 2 J.R.LORSCH,A.G.HINNEBUSCH,V.RAMAKRISHNAN
JRNL TITL CONFORMATIONAL DIFFERENCES BETWEEN OPEN AND CLOSED STATES OF
JRNL TITL 2 THE EUKARYOTIC TRANSLATION INITIATION COMPLEX.
JRNL REF MOL.CELL V. 59 399 2015
JRNL REFN ISSN 1097-2765
JRNL PMID 26212456
JRNL DOI 10.1016/J.MOLCEL.2015.06.033
REMARK 2
REMARK 2 RESOLUTION. 4.90 ANGSTROMS.
REMARK 3
REMARK 3 REFINEMENT.
REMARK 3 SOFTWARE PACKAGES : COOT, REFMAC, UCSF CHIMERA, RELION
REMARK 3 RECONSTRUCTION SCHEMA : NULL
REMARK 3
REMARK 3 EM MAP-MODEL FITTING AND REFINEMENT
REMARK 3 PDB ENTRY : 3J81
REMARK 3 REFINEMENT SPACE : RECIPROCAL
REMARK 3 REFINEMENT PROTOCOL : OTHER
REMARK 3 REFINEMENT TARGET : R-FACTOR, FSC
REMARK 3 OVERALL ANISOTROPIC B VALUE : NULL
REMARK 3
REMARK 3 FITTING PROCEDURE : METHOD--LOCAL REFINEMENT
REMARK 3
REMARK 3 EM IMAGE RECONSTRUCTION STATISTICS
REMARK 3 NOMINAL PIXEL SIZE (ANGSTROMS) : 1.340
REMARK 3 ACTUAL PIXEL SIZE (ANGSTROMS) : NULL
REMARK 3 EFFECTIVE RESOLUTION (ANGSTROMS) : 4.900
REMARK 3 NUMBER OF PARTICLES : 21401
REMARK 3 CTF CORRECTION METHOD : NULL
REMARK 3
REMARK 3 EM RECONSTRUCTION MAGNIFICATION CALIBRATION: NULL
REMARK 3
REMARK 3 OTHER DETAILS: GOLD-STANDARD
REMARK 4
REMARK 4 3JAP COMPLIES WITH FORMAT V. 3.30, 13-JUL-11
REMARK 100
REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY RCSB ON 10-JUL-15.
REMARK 100 THE DEPOSITION ID IS D_1000160463.
REMARK 245
REMARK 245 EXPERIMENTAL DETAILS
REMARK 245 RECONSTRUCTION METHOD : SINGLE PARTICLE
REMARK 245 SPECIMEN TYPE : VITREOUS ICE (CRYO EM)
REMARK 245
REMARK 245 ELECTRON MICROSCOPE SAMPLE
REMARK 245 SAMPLE TYPE : PARTICLE
REMARK 245 PARTICLE TYPE : POINT
REMARK 245 NAME OF SAMPLE : PARTIAL YEAST 48S PREINITIATION
REMARK 245 COMPLEX; 40S RIBOSOME;
REMARK 245 EUKARYOTIC INITIATION FACTOR
REMARK 245 EIF1A; EUKARYOTIC INITIATION
REMARK 245 FACTOR EIF2; EUKARYOTIC
REMARK 245 INITIATION FACTOR EIF1;
REMARK 245 EUKARYOTIC INITIATION FACTOR
REMARK 245 EIF3; MET-TRNAI; MRNA
REMARK 245 SAMPLE CONCENTRATION (MG ML-1) : 0.17
REMARK 245 SAMPLE SUPPORT DETAILS : QUANTIFOIL R2/2 400 MESH COPPER
REMARK 245 GRIDS WITH 4-5 NM THIN CARBON
REMARK 245 ON TOP
REMARK 245 SAMPLE VITRIFICATION DETAILS : BLOT FOR 2.5 TO 3 SECONDS
REMARK 245 BEFORE PLUNGING INTO LIQUID
REMARK 245 ETHANE (FEI VITROBOT MARK I).
REMARK 245 SAMPLE BUFFER : 20 MM MES-KOH, 40 MM POTASSIUM
REMARK 245 ACETATE, 10 MM AMMONIUM ACETATE,
REMARK 245 8 MM MAGNESIUM ACETATE, 2 MM
REMARK 245 DTT
REMARK 245 PH : 6.50
REMARK 245 SAMPLE DETAILS : NULL
REMARK 245
REMARK 245 DATA ACQUISITION
REMARK 245 DATE OF EXPERIMENT : 04-JUL-14
REMARK 245 NUMBER OF MICROGRAPHS-IMAGES : NULL
REMARK 245 TEMPERATURE (KELVIN) : NULL
REMARK 245 MICROSCOPE MODEL : FEI TITAN KRIOS
REMARK 245 DETECTOR TYPE : FEI FALCON II (4K X 4K)
REMARK 245 MINIMUM DEFOCUS (NM) : 1500.00
REMARK 245 MAXIMUM DEFOCUS (NM) : 4000.00
REMARK 245 MINIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 MAXIMUM TILT ANGLE (DEGREES) : NULL
REMARK 245 NOMINAL CS : 2.70
REMARK 245 IMAGING MODE : BRIGHT FIELD
REMARK 245 ELECTRON DOSE (ELECTRONS NM**-2) : 2700.00
REMARK 245 ILLUMINATION MODE : FLOOD BEAM
REMARK 245 NOMINAL MAGNIFICATION : 59000
REMARK 245 CALIBRATED MAGNIFICATION : 104478
REMARK 245 SOURCE : FIELD EMISSION GUN
REMARK 245 ACCELERATION VOLTAGE (KV) : 300
REMARK 245 IMAGING DETAILS : COMPLETE DATASET WAS
REMARK 245 COLLECTED OVER TWO NON-CONSECUTIVE DAYS.
REMARK 247
REMARK 247 ELECTRON MICROSCOPY
REMARK 247 THE COORDINATES IN THIS ENTRY WERE GENERATED FROM ELECTRON
REMARK 247 MICROSCOPY DATA. PROTEIN DATA BANK CONVENTIONS REQUIRE
REMARK 247 THAT CRYST1 AND SCALE RECORDS BE INCLUDED, BUT THE VALUES
REMARK 247 ON THESE RECORDS ARE MEANINGLESS EXCEPT FOR THE CALCULATION
REMARK 247 OF THE STRUCTURE FACTORS.
REMARK 300
REMARK 300 BIOMOLECULE: 1
REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM
REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN
REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON
REMARK 300 BURIED SURFACE AREA.
REMARK 350
REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN
REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE
REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS
REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND
REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN.
REMARK 350
REMARK 350 BIOMOLECULE: 1
REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: 47-MERIC
REMARK 350 APPLY THE FOLLOWING TO CHAINS: 1, 2, 3, A, B, C, D, E, F, G,
REMARK 350 AND CHAINS: H, I, J, K, L, M, N, O, P,
REMARK 350 AND CHAINS: Q, R, S, T, U, V, W, X, Y, Z,
REMARK 350 AND CHAINS: a, b, c, d, e, f, g, h, i,
REMARK 350 AND CHAINS: j, k, l, m, o, p, q, r, s
REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000
REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000
REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000
REMARK 465
REMARK 465 MISSING RESIDUES
REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE
REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.)
REMARK 465
REMARK 465 M RES C SSSEQI
REMARK 465 C 2 675
REMARK 465 G 3 0
REMARK 465 G 3 1
REMARK 465 A 3 2
REMARK 465 U 3 17
REMARK 465 C 3 18
REMARK 465 U 3 19
REMARK 465 C 3 20
REMARK 465 U 3 21
REMARK 465 C 3 22
REMARK 465 U 3 23
REMARK 465 C 3 24
REMARK 465 MET A 1
REMARK 465 ILE A 210
REMARK 465 GLU A 211
REMARK 465 GLN A 212
REMARK 465 GLN A 213
REMARK 465 THR A 214
REMARK 465 ALA A 215
REMARK 465 GLU A 216
REMARK 465 GLU A 217
REMARK 465 GLU A 218
REMARK 465 ALA A 219
REMARK 465 VAL A 220
REMARK 465 ALA A 221
REMARK 465 SER A 222
REMARK 465 GLY A 223
REMARK 465 GLU A 224
REMARK 465 GLN A 225
REMARK 465 THR A 226
REMARK 465 GLU A 227
REMARK 465 GLU A 228
REMARK 465 ALA A 229
REMARK 465 VAL A 230
REMARK 465 ASP A 231
REMARK 465 ALA A 232
REMARK 465 THR A 233
REMARK 465 GLU A 234
REMARK 465 GLU A 235
REMARK 465 GLN A 236
REMARK 465 THR A 237
REMARK 465 GLU A 238
REMARK 465 ALA A 239
REMARK 465 ALA A 240
REMARK 465 GLU A 241
REMARK 465 TRP A 242
REMARK 465 ALA A 243
REMARK 465 GLU A 244
REMARK 465 GLU A 245
REMARK 465 GLY A 246
REMARK 465 GLN A 247
REMARK 465 ALA A 248
REMARK 465 GLN A 249
REMARK 465 GLU A 250
REMARK 465 GLU A 251
REMARK 465 GLU A 252
REMARK 465 TRP A 253
REMARK 465 ASN A 254
REMARK 465 MET B 1
REMARK 465 ALA B 2
REMARK 465 SER B 10
REMARK 465 LYS B 11
REMARK 465 GLY B 12
REMARK 465 LYS B 13
REMARK 465 LYS B 14
REMARK 465 GLY B 15
REMARK 465 LEU B 16
REMARK 465 LYS B 17
REMARK 465 LYS B 18
REMARK 465 GLU B 234
REMARK 465 ALA B 235
REMARK 465 SER B 236
REMARK 465 ALA B 237
REMARK 465 GLU B 238
REMARK 465 GLU B 239
REMARK 465 LYS B 240
REMARK 465 GLY B 241
REMARK 465 LYS B 242
REMARK 465 LYS B 243
REMARK 465 VAL B 244
REMARK 465 ALA B 245
REMARK 465 GLY B 246
REMARK 465 PHE B 247
REMARK 465 LYS B 248
REMARK 465 ASP B 249
REMARK 465 GLU B 250
REMARK 465 ILE B 251
REMARK 465 LEU B 252
REMARK 465 GLU B 253
REMARK 465 THR B 254
REMARK 465 VAL B 255
REMARK 465 MET C 1
REMARK 465 SER C 2
REMARK 465 ALA C 3
REMARK 465 PRO C 4
REMARK 465 GLN C 5
REMARK 465 ALA C 6
REMARK 465 GLN C 7
REMARK 465 GLY C 8
REMARK 465 GLN C 9
REMARK 465 GLN C 10
REMARK 465 ALA C 11
REMARK 465 PRO C 12
REMARK 465 ARG C 13
REMARK 465 ARG C 14
REMARK 465 GLY C 15
REMARK 465 GLY C 16
REMARK 465 PHE C 17
REMARK 465 GLY C 18
REMARK 465 GLY C 19
REMARK 465 ALA C 20
REMARK 465 ASN C 21
REMARK 465 ARG C 22
REMARK 465 GLY C 23
REMARK 465 GLY C 24
REMARK 465 ARG C 25
REMARK 465 GLY C 26
REMARK 465 GLY C 27
REMARK 465 ARG C 28
REMARK 465 ARG C 29
REMARK 465 GLY C 30
REMARK 465 GLY C 31
REMARK 465 ARG C 32
REMARK 465 ARG C 33
REMARK 465 ASP C 34
REMARK 465 GLN C 35
REMARK 465 GLU C 36
REMARK 465 GLU C 37
REMARK 465 LYS C 38
REMARK 465 LYS C 256
REMARK 465 LYS C 257
REMARK 465 LYS C 258
REMARK 465 LEU C 259
REMARK 465 MET D 1
REMARK 465 VAL D 2
REMARK 465 ARG D 226
REMARK 465 PRO D 227
REMARK 465 THR D 228
REMARK 465 GLU D 229
REMARK 465 PRO D 230
REMARK 465 VAL D 231
REMARK 465 GLU D 232
REMARK 465 ALA D 233
REMARK 465 ALA D 234
REMARK 465 GLU D 235
REMARK 465 SER D 236
REMARK 465 ALA D 237
REMARK 465 MET E 1
REMARK 465 MET F 1
REMARK 465 SER F 2
REMARK 465 GLU F 3
REMARK 465 HIS F 4
REMARK 465 GLU F 5
REMARK 465 ALA F 6
REMARK 465 GLN F 7
REMARK 465 VAL F 8
REMARK 465 GLU F 9
REMARK 465 VAL F 10
REMARK 465 GLU F 11
REMARK 465 VAL F 12
REMARK 465 GLN F 13
REMARK 465 GLU F 14
REMARK 465 ASP F 15
REMARK 465 PHE F 16
REMARK 465 GLU F 17
REMARK 465 VAL F 18
REMARK 465 VAL F 19
REMARK 465 GLN F 20
REMARK 465 GLU F 21
REMARK 465 ARG G 227
REMARK 465 LYS G 228
REMARK 465 ARG G 229
REMARK 465 ARG G 230
REMARK 465 ALA G 231
REMARK 465 SER G 232
REMARK 465 SER G 233
REMARK 465 LEU G 234
REMARK 465 LYS G 235
REMARK 465 ALA G 236
REMARK 465 MET H 1
REMARK 465 SER H 2
REMARK 465 ASP H 3
REMARK 465 GLU H 188
REMARK 465 THR H 189
REMARK 465 HIS H 190
REMARK 465 MET I 1
REMARK 465 LYS I 124
REMARK 465 LYS I 125
REMARK 465 ASN I 126
REMARK 465 THR I 127
REMARK 465 LYS I 128
REMARK 465 ALA I 129
REMARK 465 GLU I 130
REMARK 465 GLU I 131
REMARK 465 GLU I 132
REMARK 465 THR I 133
REMARK 465 ALA I 134
REMARK 465 THR I 135
REMARK 465 MET J 1
REMARK 465 GLU J 184
REMARK 465 ALA J 185
REMARK 465 ASP J 186
REMARK 465 GLU J 187
REMARK 465 GLU J 188
REMARK 465 GLY K 97
REMARK 465 ASP K 98
REMARK 465 GLN K 99
REMARK 465 ARG K 100
REMARK 465 PRO K 101
REMARK 465 GLN K 102
REMARK 465 GLY K 103
REMARK 465 LYS K 104
REMARK 465 LYS K 105
REMARK 465 TYR K 106
REMARK 465 MET L 1
REMARK 465 MET M 1
REMARK 465 SER M 2
REMARK 465 ASP M 3
REMARK 465 VAL M 4
REMARK 465 GLU M 5
REMARK 465 GLU M 6
REMARK 465 VAL M 7
REMARK 465 GLN M 8
REMARK 465 GLN M 9
REMARK 465 VAL M 10
REMARK 465 PRO M 11
REMARK 465 VAL M 12
REMARK 465 ALA M 13
REMARK 465 GLU M 14
REMARK 465 LEU M 15
REMARK 465 THR M 16
REMARK 465 ASN M 75
REMARK 465 MET N 1
REMARK 465 MET O 1
REMARK 465 ALA O 2
REMARK 465 ASN O 3
REMARK 465 VAL O 4
REMARK 465 VAL O 5
REMARK 465 GLN O 6
REMARK 465 ALA O 7
REMARK 465 LYS O 8
REMARK 465 ASP O 9
REMARK 465 ASN O 10
REMARK 465 MET P 1
REMARK 465 SER P 2
REMARK 465 GLU P 3
REMARK 465 ALA P 4
REMARK 465 ALA P 5
REMARK 465 ALA P 6
REMARK 465 PRO P 7
REMARK 465 ARG P 8
REMARK 465 LYS P 9
REMARK 465 ARG P 10
REMARK 465 SER P 11
REMARK 465 PHE P 12
REMARK 465 ARG P 130
REMARK 465 ALA P 131
REMARK 465 GLY P 132
REMARK 465 ALA P 133
REMARK 465 THR P 134
REMARK 465 THR P 135
REMARK 465 SER P 136
REMARK 465 ARG P 137
REMARK 465 PHE P 138
REMARK 465 ILE P 139
REMARK 465 PRO P 140
REMARK 465 LEU P 141
REMARK 465 ARG P 142
REMARK 465 MET Q 1
REMARK 465 SER Q 2
REMARK 465 MET R 1
REMARK 465 ALA R 90
REMARK 465 LEU R 91
REMARK 465 ASP R 92
REMARK 465 LEU R 93
REMARK 465 SER R 94
REMARK 465 VAL R 127
REMARK 465 ARG R 128
REMARK 465 ASP R 129
REMARK 465 ARG R 130
REMARK 465 ARG R 131
REMARK 465 PHE R 132
REMARK 465 ARG R 133
REMARK 465 LYS R 134
REMARK 465 ARG R 135
REMARK 465 ASN R 136
REMARK 465 MET S 1
REMARK 465 MET T 1
REMARK 465 MET U 4
REMARK 465 SER U 5
REMARK 465 GLN U 6
REMARK 465 VAL U 7
REMARK 465 GLU U 8
REMARK 465 LYS U 9
REMARK 465 LYS U 10
REMARK 465 SER U 11
REMARK 465 GLU U 12
REMARK 465 GLN U 13
REMARK 465 GLN U 14
REMARK 465 MET W 1
REMARK 465 MET X 1
REMARK 465 MET Y 1
REMARK 465 MET Z 1
REMARK 465 PRO Z 2
REMARK 465 PRO Z 3
REMARK 465 LYS Z 4
REMARK 465 GLN Z 5
REMARK 465 GLN Z 6
REMARK 465 LEU Z 7
REMARK 465 SER Z 8
REMARK 465 LYS Z 9
REMARK 465 ALA Z 10
REMARK 465 ALA Z 11
REMARK 465 LYS Z 12
REMARK 465 ALA Z 13
REMARK 465 ALA Z 14
REMARK 465 ALA Z 15
REMARK 465 ALA Z 16
REMARK 465 MET Z 17
REMARK 465 ALA Z 18
REMARK 465 GLY Z 19
REMARK 465 GLY Z 20
REMARK 465 LYS Z 21
REMARK 465 LYS Z 22
REMARK 465 SER Z 23
REMARK 465 LYS Z 24
REMARK 465 LYS Z 25
REMARK 465 LYS Z 26
REMARK 465 TRP Z 27
REMARK 465 SER Z 28
REMARK 465 LYS Z 29
REMARK 465 LYS Z 30
REMARK 465 SER Z 31
REMARK 465 HIS Z 32
REMARK 465 LYS Z 33
REMARK 465 ASP Z 34
REMARK 465 LYS Z 35
REMARK 465 ALA Z 106
REMARK 465 SER Z 107
REMARK 465 GLU Z 108
REMARK 465 MET a 1
REMARK 465 ARG a 100
REMARK 465 PRO a 101
REMARK 465 ARG a 102
REMARK 465 PHE a 103
REMARK 465 ASN a 104
REMARK 465 ARG a 105
REMARK 465 ASP a 106
REMARK 465 ASN a 107
REMARK 465 LYS a 108
REMARK 465 VAL a 109
REMARK 465 SER a 110
REMARK 465 PRO a 111
REMARK 465 ALA a 112
REMARK 465 ASP a 113
REMARK 465 ALA a 114
REMARK 465 ALA a 115
REMARK 465 LYS a 116
REMARK 465 LYS a 117
REMARK 465 ALA a 118
REMARK 465 LEU a 119
REMARK 465 MET b 1
REMARK 465 MET c 1
REMARK 465 ASP c 2
REMARK 465 THR c 3
REMARK 465 LYS c 4
REMARK 465 THR c 5
REMARK 465 MET d 1
REMARK 465 ALA d 2
REMARK 465 HIS d 3
REMARK 465 MET e 1
REMARK 465 GLY e 2
REMARK 465 LYS e 3
REMARK 465 VAL e 4
REMARK 465 HIS e 5
REMARK 465 GLY e 6
REMARK 465 SER e 7
REMARK 465 SER e 62
REMARK 465 GLN e 63
REMARK 465 MET f 1
REMARK 465 GLN f 2
REMARK 465 ILE f 3
REMARK 465 PHE f 4
REMARK 465 VAL f 5
REMARK 465 LYS f 6
REMARK 465 THR f 7
REMARK 465 LEU f 8
REMARK 465 THR f 9
REMARK 465 GLY f 10
REMARK 465 LYS f 11
REMARK 465 THR f 12
REMARK 465 ILE f 13
REMARK 465 THR f 14
REMARK 465 LEU f 15
REMARK 465 GLU f 16
REMARK 465 VAL f 17
REMARK 465 GLU f 18
REMARK 465 SER f 19
REMARK 465 SER f 20
REMARK 465 ASP f 21
REMARK 465 THR f 22
REMARK 465 ILE f 23
REMARK 465 ASP f 24
REMARK 465 ASN f 25
REMARK 465 VAL f 26
REMARK 465 LYS f 27
REMARK 465 SER f 28
REMARK 465 LYS f 29
REMARK 465 ILE f 30
REMARK 465 GLN f 31
REMARK 465 ASP f 32
REMARK 465 LYS f 33
REMARK 465 GLU f 34
REMARK 465 GLY f 35
REMARK 465 ILE f 36
REMARK 465 PRO f 37
REMARK 465 PRO f 38
REMARK 465 ASP f 39
REMARK 465 GLN f 40
REMARK 465 GLN f 41
REMARK 465 ARG f 42
REMARK 465 LEU f 43
REMARK 465 ILE f 44
REMARK 465 PHE f 45
REMARK 465 ALA f 46
REMARK 465 GLY f 47
REMARK 465 LYS f 48
REMARK 465 GLN f 49
REMARK 465 LEU f 50
REMARK 465 GLU f 51
REMARK 465 ASP f 52
REMARK 465 GLY f 53
REMARK 465 ARG f 54
REMARK 465 THR f 55
REMARK 465 LEU f 56
REMARK 465 SER f 57
REMARK 465 ASP f 58
REMARK 465 TYR f 59
REMARK 465 ASN f 60
REMARK 465 ILE f 61
REMARK 465 GLN f 62
REMARK 465 LYS f 63
REMARK 465 GLU f 64
REMARK 465 SER f 65
REMARK 465 THR f 66
REMARK 465 LEU f 67
REMARK 465 HIS f 68
REMARK 465 LEU f 69
REMARK 465 VAL f 70
REMARK 465 LEU f 71
REMARK 465 ARG f 72
REMARK 465 LEU f 73
REMARK 465 ARG f 74
REMARK 465 GLY f 75
REMARK 465 GLY f 76
REMARK 465 GLY f 77
REMARK 465 LYS f 78
REMARK 465 LYS f 79
REMARK 465 ARG f 80
REMARK 465 LYS f 81
REMARK 465 MET g 1
REMARK 465 SER g 2
REMARK 465 GLU g 163
REMARK 465 ASP g 164
REMARK 465 GLY g 165
REMARK 465 GLU g 166
REMARK 465 GLU g 190
REMARK 465 ASP g 191
REMARK 465 MET i 1
REMARK 465 GLY i 2
REMARK 465 LYS i 3
REMARK 465 LYS i 4
REMARK 465 ASN i 116
REMARK 465 GLU i 117
REMARK 465 THR i 118
REMARK 465 ASP i 119
REMARK 465 ASN i 120
REMARK 465 PHE i 121
REMARK 465 GLY i 122
REMARK 465 PHE i 123
REMARK 465 GLU i 124
REMARK 465 SER i 125
REMARK 465 ASP i 126
REMARK 465 GLU i 127
REMARK 465 ASP i 128
REMARK 465 VAL i 129
REMARK 465 ASN i 130
REMARK 465 PHE i 131
REMARK 465 GLU i 132
REMARK 465 PHE i 133
REMARK 465 GLY i 134
REMARK 465 ASN i 135
REMARK 465 ALA i 136
REMARK 465 ASP i 137
REMARK 465 GLU i 138
REMARK 465 ASP i 139
REMARK 465 ASP i 140
REMARK 465 GLU i 141
REMARK 465 GLU i 142
REMARK 465 GLY i 143
REMARK 465 GLU i 144
REMARK 465 ASP i 145
REMARK 465 GLU i 146
REMARK 465 GLU i 147
REMARK 465 LEU i 148
REMARK 465 ASP i 149
REMARK 465 ILE i 150
REMARK 465 ASP i 151
REMARK 465 ASP i 152
REMARK 465 ILE i 153
REMARK 465 MET j 1
REMARK 465 SER j 2
REMARK 465 LYS j 175
REMARK 465 ARG j 176
REMARK 465 LEU j 177
REMARK 465 THR j 178
REMARK 465 PRO j 179
REMARK 465 GLN j 180
REMARK 465 ALA j 181
REMARK 465 MET j 211
REMARK 465 SER j 212
REMARK 465 THR j 213
REMARK 465 GLU j 214
REMARK 465 GLN j 215
REMARK 465 MET j 216
REMARK 465 GLN j 217
REMARK 465 MET j 266
REMARK 465 PRO j 267
REMARK 465 PRO j 268
REMARK 465 LYS j 269
REMARK 465 ALA j 270
REMARK 465 VAL j 271
REMARK 465 THR j 272
REMARK 465 ALA j 273
REMARK 465 THR j 274
REMARK 465 GLU j 275
REMARK 465 ASP j 276
REMARK 465 ALA j 277
REMARK 465 GLU j 278
REMARK 465 LEU j 279
REMARK 465 GLN j 280
REMARK 465 ALA j 281
REMARK 465 LEU j 282
REMARK 465 LEU j 283
REMARK 465 GLU j 284
REMARK 465 SER j 285
REMARK 465 LYS j 286
REMARK 465 GLU j 287
REMARK 465 LEU j 288
REMARK 465 ASP j 289
REMARK 465 ASN j 290
REMARK 465 ARG j 291
REMARK 465 SER j 292
REMARK 465 ASP j 293
REMARK 465 SER j 294
REMARK 465 GLU j 295
REMARK 465 ASP j 296
REMARK 465 ASP j 297
REMARK 465 GLU j 298
REMARK 465 ASP j 299
REMARK 465 GLU j 300
REMARK 465 SER j 301
REMARK 465 ASP j 302
REMARK 465 ASP j 303
REMARK 465 GLU j 304
REMARK 465 MET k 1
REMARK 465 SER k 2
REMARK 465 ASP k 3
REMARK 465 LEU k 4
REMARK 465 GLN k 5
REMARK 465 ASP k 6
REMARK 465 GLN k 7
REMARK 465 GLU k 8
REMARK 465 PRO k 9
REMARK 465 SER k 10
REMARK 465 ILE k 11
REMARK 465 ILE k 12
REMARK 465 ILE k 13
REMARK 465 ASN k 14
REMARK 465 GLY k 15
REMARK 465 ASN k 16
REMARK 465 LEU k 17
REMARK 465 GLU k 18
REMARK 465 PRO k 19
REMARK 465 VAL k 20
REMARK 465 GLY k 21
REMARK 465 GLU k 22
REMARK 465 PRO k 23
REMARK 465 ASP k 24
REMARK 465 ILE k 25
REMARK 465 VAL k 26
REMARK 465 GLU k 27
REMARK 465 GLU k 28
REMARK 465 THR k 29
REMARK 465 GLU k 30
REMARK 465 VAL k 31
REMARK 465 VAL k 32
REMARK 465 ALA k 33
REMARK 465 GLN k 34
REMARK 465 GLU k 35
REMARK 465 THR k 36
REMARK 465 GLN k 37
REMARK 465 GLU k 38
REMARK 465 THR k 39
REMARK 465 GLN k 40
REMARK 465 ASP k 41
REMARK 465 ALA k 42
REMARK 465 ASP k 43
REMARK 465 LYS k 44
REMARK 465 PRO k 45
REMARK 465 LYS k 46
REMARK 465 LYS k 47
REMARK 465 LYS k 48
REMARK 465 VAL k 49
REMARK 465 ALA k 50
REMARK 465 PHE k 51
REMARK 465 THR k 52
REMARK 465 GLY k 53
REMARK 465 LEU k 54
REMARK 465 GLU k 55
REMARK 465 GLU k 56
REMARK 465 ASP k 57
REMARK 465 GLY k 58
REMARK 465 GLU k 59
REMARK 465 THR k 60
REMARK 465 GLU k 61
REMARK 465 GLU k 62
REMARK 465 GLU k 63
REMARK 465 LYS k 64
REMARK 465 ARG k 65
REMARK 465 LYS k 66
REMARK 465 ARG k 67
REMARK 465 GLU k 68
REMARK 465 PHE k 69
REMARK 465 GLU k 70
REMARK 465 GLU k 71
REMARK 465 GLY k 72
REMARK 465 GLY k 73
REMARK 465 GLY k 74
REMARK 465 LEU k 75
REMARK 465 PRO k 76
REMARK 465 GLU k 77
REMARK 465 GLN k 78
REMARK 465 PRO k 79
REMARK 465 LEU k 80
REMARK 465 ASN k 81
REMARK 465 PRO k 82
REMARK 465 ASP k 83
REMARK 465 PHE k 84
REMARK 465 SER k 85
REMARK 465 LYS k 86
REMARK 465 LEU k 87
REMARK 465 ASN k 88
REMARK 465 PRO k 89
REMARK 465 LEU k 90
REMARK 465 SER k 91
REMARK 465 ALA k 92
REMARK 465 GLU k 93
REMARK 465 ILE k 94
REMARK 465 ILE k 95
REMARK 465 ASN k 96
REMARK 465 ARG k 97
REMARK 465 PRO k 153
REMARK 465 THR k 154
REMARK 465 CYS k 155
REMARK 465 PRO k 156
REMARK 465 GLU k 157
REMARK 465 PRO k 158
REMARK 465 ASP k 159
REMARK 465 CYS k 160
REMARK 465 TYR k 161
REMARK 465 ARG k 162
REMARK 465 SER k 163
REMARK 465 PHE k 164
REMARK 465 LYS k 165
REMARK 465 SER k 166
REMARK 465 ASP k 167
REMARK 465 LYS k 168
REMARK 465 LYS k 362
REMARK 465 ASP k 363
REMARK 465 ASP k 364
REMARK 465 LYS k 365
REMARK 465 GLY k 366
REMARK 465 LYS k 367
REMARK 465 THR k 445
REMARK 465 ASP k 446
REMARK 465 GLY k 447
REMARK 465 GLN k 448
REMARK 465 GLY k 520
REMARK 465 THR k 521
REMARK 465 THR k 522
REMARK 465 LEU k 523
REMARK 465 GLU k 524
REMARK 465 PRO k 525
REMARK 465 ILE k 526
REMARK 465 ALA k 527
REMARK 465 MET l 1
REMARK 465 SER l 2
REMARK 465 SER l 3
REMARK 465 ASP l 4
REMARK 465 LEU l 5
REMARK 465 ALA l 6
REMARK 465 ALA l 7
REMARK 465 GLU l 8
REMARK 465 LEU l 9
REMARK 465 GLY l 10
REMARK 465 PHE l 11
REMARK 465 ASP l 12
REMARK 465 PRO l 13
REMARK 465 ALA l 14
REMARK 465 LEU l 15
REMARK 465 LYS l 16
REMARK 465 LYS l 17
REMARK 465 LYS l 18
REMARK 465 LYS l 19
REMARK 465 LYS l 20
REMARK 465 THR l 21
REMARK 465 LYS l 22
REMARK 465 LYS l 23
REMARK 465 VAL l 24
REMARK 465 ILE l 25
REMARK 465 PRO l 26
REMARK 465 ASP l 27
REMARK 465 ASP l 28
REMARK 465 PHE l 29
REMARK 465 ASP l 30
REMARK 465 ALA l 31
REMARK 465 ALA l 32
REMARK 465 VAL l 33
REMARK 465 ASN l 34
REMARK 465 GLY l 35
REMARK 465 LYS l 36
REMARK 465 GLU l 37
REMARK 465 ASN l 38
REMARK 465 GLY l 39
REMARK 465 SER l 40
REMARK 465 GLY l 41
REMARK 465 ASP l 42
REMARK 465 ASP l 43
REMARK 465 LEU l 44
REMARK 465 PHE l 45
REMARK 465 ALA l 46
REMARK 465 GLY l 47
REMARK 465 LEU l 48
REMARK 465 LYS l 49
REMARK 465 LYS l 50
REMARK 465 LYS l 51
REMARK 465 LYS l 52
REMARK 465 LYS l 53
REMARK 465 LYS l 54
REMARK 465 SER l 55
REMARK 465 LYS l 56
REMARK 465 SER l 57
REMARK 465 VAL l 58
REMARK 465 SER l 59
REMARK 465 ALA l 60
REMARK 465 ASP l 61
REMARK 465 ALA l 62
REMARK 465 GLU l 63
REMARK 465 ALA l 64
REMARK 465 GLU l 65
REMARK 465 LYS l 66
REMARK 465 GLU l 67
REMARK 465 PRO l 68
REMARK 465 THR l 69
REMARK 465 ASP l 70
REMARK 465 ASP l 71
REMARK 465 ILE l 72
REMARK 465 ALA l 73
REMARK 465 GLU l 74
REMARK 465 ALA l 75
REMARK 465 LEU l 76
REMARK 465 GLY l 77
REMARK 465 GLU l 78
REMARK 465 LEU l 79
REMARK 465 SER l 80
REMARK 465 LEU l 81
REMARK 465 LYS l 82
REMARK 465 LYS l 83
REMARK 465 LYS l 84
REMARK 465 LYS l 85
REMARK 465 LYS l 86
REMARK 465 LYS l 87
REMARK 465 THR l 88
REMARK 465 LYS l 89
REMARK 465 ASP l 90
REMARK 465 SER l 91
REMARK 465 SER l 92
REMARK 465 VAL l 93
REMARK 465 ASP l 94
REMARK 465 ALA l 95
REMARK 465 PHE l 96
REMARK 465 GLU l 97
REMARK 465 LYS l 98
REMARK 465 GLU l 99
REMARK 465 LEU l 100
REMARK 465 ALA l 101
REMARK 465 LYS l 102
REMARK 465 ALA l 103
REMARK 465 GLY l 104
REMARK 465 LEU l 105
REMARK 465 ASP l 106
REMARK 465 ASN l 107
REMARK 465 VAL l 108
REMARK 465 ASP l 109
REMARK 465 ALA l 110
REMARK 465 GLU l 111
REMARK 465 SER l 112
REMARK 465 LYS l 113
REMARK 465 GLU l 114
REMARK 465 GLY l 115
REMARK 465 THR l 116
REMARK 465 PRO l 117
REMARK 465 SER l 118
REMARK 465 ALA l 119
REMARK 465 ASN l 120
REMARK 465 SER l 121
REMARK 465 SER l 122
REMARK 465 ILE l 123
REMARK 465 GLN l 124
REMARK 465 GLN l 125
REMARK 465 GLU l 126
REMARK 465 THR l 144
REMARK 465 ASN l 145
REMARK 465 ASN l 146
REMARK 465 PRO l 147
REMARK 465 GLU l 148
REMARK 465 LEU l 149
REMARK 465 ALA l 150
REMARK 465 GLY l 151
REMARK 465 ASP l 152
REMARK 465 ARG l 153
REMARK 465 SER l 154
REMARK 465 GLY l 155
REMARK 465 PRO l 156
REMARK 465 GLN l 208
REMARK 465 GLN l 250
REMARK 465 SER l 251
REMARK 465 ILE l 271
REMARK 465 LYS l 272
REMARK 465 THR l 273
REMARK 465 GLY l 274
REMARK 465 PHE l 275
REMARK 465 GLN l 276
REMARK 465 ALA l 277
REMARK 465 THR l 278
REMARK 465 VAL l 279
REMARK 465 GLY l 280
REMARK 465 LYS l 281
REMARK 465 ARG l 282
REMARK 465 ARG l 283
REMARK 465 ARG l 284
REMARK 465 MET l 285
REMARK 465 MET m 1
REMARK 465 SER m 2
REMARK 465 ILE m 3
REMARK 465 GLU m 4
REMARK 465 ASN m 5
REMARK 465 LEU m 6
REMARK 465 LYS m 7
REMARK 465 SER m 8
REMARK 465 PHE m 9
REMARK 465 ASP m 10
REMARK 465 PRO m 11
REMARK 465 PHE m 12
REMARK 465 ALA m 13
REMARK 465 ASP m 14
REMARK 465 THR m 15
REMARK 465 GLY m 16
REMARK 465 ASP m 17
REMARK 465 ASP m 18
REMARK 465 MET o 1
REMARK 465 ALA o 2
REMARK 465 PRO o 3
REMARK 465 PRO o 4
REMARK 465 PRO o 5
REMARK 465 ASP o 121
REMARK 465 ASP o 122
REMARK 465 LEU o 123
REMARK 465 GLU o 124
REMARK 465 GLY o 125
REMARK 465 GLY o 126
REMARK 465 VAL o 127
REMARK 465 THR o 128
REMARK 465 PRO o 129
REMARK 465 GLU o 130
REMARK 465 ASN o 131
REMARK 465 LEU o 132
REMARK 465 LEU o 133
REMARK 465 ILE o 134
REMARK 465 SER o 135
REMARK 465 VAL o 136
REMARK 465 TYR o 137
REMARK 465 GLU o 138
REMARK 465 SER o 139
REMARK 465 ASP o 140
REMARK 465 GLN o 141
REMARK 465 SER o 142
REMARK 465 VAL o 143
REMARK 465 ALA o 144
REMARK 465 GLY o 145
REMARK 465 PHE o 146
REMARK 465 ASN o 147
REMARK 465 ASP o 148
REMARK 465 GLU o 149
REMARK 465 LEU o 224
REMARK 465 VAL o 225
REMARK 465 ASP o 226
REMARK 465 LEU o 227
REMARK 465 ASN p 795
REMARK 465 LYS p 796
REMARK 465 GLU p 797
REMARK 465 TYR p 798
REMARK 465 LYS p 799
REMARK 465 ILE p 800
REMARK 465 ALA p 801
REMARK 465 LYS p 802
REMARK 465 GLU p 803
REMARK 465 ARG p 804
REMARK 465 LEU p 805
REMARK 465 ASN p 806
REMARK 465 PRO p 807
REMARK 465 PRO p 808
REMARK 465 SER p 809
REMARK 465 ASN p 810
REMARK 465 ARG p 811
REMARK 465 ARG p 812
REMARK 465 MET q 343
REMARK 465 GLN q 344
REMARK 465 GLU q 345
REMARK 465 ALA q 346
REMARK 465 ASN q 347
REMARK 470
REMARK 470 MISSING ATOM
REMARK 470 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 470 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 470 I=INSERTION CODE):
REMARK 470 M RES CSSEQI ATOMS
REMARK 470 A 21692 N9 C8 N7 C5 C6 N6 N1
REMARK 470 A 21692 C2 N3 C4
REMARK 470 G 21693 N9 C8 N7 C5 C6 O6 N1
REMARK 470 G 21693 C2 N2 N3 C4
REMARK 470 G 21694 N9 C8 N7 C5 C6 O6 N1
REMARK 470 G 21694 C2 N2 N3 C4
REMARK 470 G 21695 N9 C8 N7 C5 C6 O6 N1
REMARK 470 G 21695 C2 N2 N3 C4
REMARK 470 G 21696 N9 C8 N7 C5 C6 O6 N1
REMARK 470 G 21696 C2 N2 N3 C4
REMARK 470 G 21697 N9 C8 N7 C5 C6 O6 N1
REMARK 470 G 21697 C2 N2 N3 C4
REMARK 470 C 21698 N1 C2 O2 N3 C4 N4 C5
REMARK 470 C 21698 C6
REMARK 470 A 21699 N9 C8 N7 C5 C6 N6 N1
REMARK 470 A 21699 C2 N3 C4
REMARK 470 A 21700 N9 C8 N7 C5 C6 N6 N1
REMARK 470 A 21700 C2 N3 C4
REMARK 470 C 21701 N1 C2 O2 N3 C4 N4 C5
REMARK 470 C 21701 C6
REMARK 470 U 21702 N1 C2 O2 N3 C4 O4 C5
REMARK 470 U 21702 C6
REMARK 470 C 21703 N1 C2 O2 N3 C4 N4 C5
REMARK 470 C 21703 C6
REMARK 470 C 21704 N1 C2 O2 N3 C4 N4 C5
REMARK 470 C 21704 C6
REMARK 470 A 21705 N9 C8 N7 C5 C6 N6 N1
REMARK 470 A 21705 C2 N3 C4
REMARK 470 LYS A 27 CG CD CE NZ
REMARK 470 GLU A 209 CG CD OE1 OE2
REMARK 470 LYS B 5 CG CD CE NZ
REMARK 470 ASN B 6 CG OD1 ND2
REMARK 470 LYS B 7 CG CD CE NZ
REMARK 470 LEU B 9 CG CD1 CD2
REMARK 470 ARG B 19 CG CD NE CZ NH1 NH2
REMARK 470 LYS I 123 CG CD CE NZ
REMARK 470 LEU e 8 CG CD1 CD2
REMARK 470 ASN f 123 CG OD1 ND2
REMARK 470 GLN f 149 CG CD OE1 NE2
REMARK 470 LYS f 150 CG CD CE NZ
REMARK 470 TYR k 183 CG CD1 CD2 CE1 CE2 CZ OH
REMARK 470 GLU m 19 CG CD OE1 OE2
REMARK 470 THR m 20 OG1 CG2
REMARK 470 SER m 23 OG
REMARK 470 ARG p 193 CG CD NE CZ NH1 NH2
REMARK 470 ASN p 196 CG OD1 ND2
REMARK 470 THR p 197 OG1 CG2
REMARK 470 THR p 198 OG1 CG2
REMARK 470 LYS p 199 CG CD CE NZ
REMARK 470 GLN p 200 CG CD OE1 NE2
REMARK 470 ARG p 201 CG CD NE CZ NH1 NH2
REMARK 470 VAL p 202 CG1 CG2
REMARK 470 LYS p 203 CG CD CE NZ
REMARK 470 LYS p 204 CG CD CE NZ
REMARK 470 VAL p 205 CG1 CG2
REMARK 470 SER p 206 OG
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: CLOSE CONTACTS IN SAME ASYMMETRIC UNIT
REMARK 500
REMARK 500 THE FOLLOWING ATOMS ARE IN CLOSE CONTACT.
REMARK 500
REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI DISTANCE
REMARK 500 MG MG 2 1876 MG MG 2 1879 1.31
REMARK 500 SG CYS l 236 ZN ZN l 301 1.63
REMARK 500 O4 U 2 1292 N1 A 2 1321 1.89
REMARK 500 N1 A 2 480 O4 U 2 506 1.89
REMARK 500 N1 A 2 991 O4 U 2 1011 1.92
REMARK 500 O PHE l 158 N ILE l 160 1.96
REMARK 500 O4 U 2 1583 N1 A 2 1609 2.06
REMARK 500 O6 G 2 763 O6 G 2 772 2.14
REMARK 500 N2 G 2 567 N2 G 2 573 2.19
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND LENGTHS
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,2(A3,1X,A1,I4,A1,1X,A4,3X),1X,F6.3)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 RES CSSEQI ATM2 DEVIATION
REMARK 500 A 1 1 P A 1 1 OP3 -0.119
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: COVALENT BOND ANGLES
REMARK 500
REMARK 500 THE STEREOCHEMICAL PARAMETERS OF THE FOLLOWING RESIDUES
REMARK 500 HAVE VALUES WHICH DEVIATE FROM EXPECTED VALUES BY MORE
REMARK 500 THAN 6*RMSD (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN
REMARK 500 IDENTIFIER; SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT: (10X,I3,1X,A3,1X,A1,I4,A1,3(1X,A4,2X),12X,F5.1)
REMARK 500
REMARK 500 EXPECTED VALUES PROTEIN: ENGH AND HUBER, 1999
REMARK 500 EXPECTED VALUES NUCLEIC ACID: CLOWNEY ET AL 1996
REMARK 500
REMARK 500 M RES CSSEQI ATM1 ATM2 ATM3
REMARK 500 A 2 685 C2' - C3' - O3' ANGL. DEV. = 13.6 DEGREES
REMARK 500 LEU I 29 CA - CB - CG ANGL. DEV. = 16.7 DEGREES
REMARK 500 PRO U 96 C - N - CA ANGL. DEV. = 10.1 DEGREES
REMARK 500 LEU W 26 CA - CB - CG ANGL. DEV. = 14.0 DEGREES
REMARK 500 PRO X 64 C - N - CD ANGL. DEV. = -13.4 DEGREES
REMARK 500 LEU j 166 CA - CB - CG ANGL. DEV. = 15.3 DEGREES
REMARK 500 LEU l 191 CA - CB - CG ANGL. DEV. = 14.9 DEGREES
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: TORSION ANGLES
REMARK 500
REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS:
REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE).
REMARK 500
REMARK 500 STANDARD TABLE:
REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2)
REMARK 500
REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI-
REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400
REMARK 500
REMARK 500 M RES CSSEQI PSI PHI
REMARK 500 PRO A 4 42.21 -83.98
REMARK 500 SER A 5 9.72 59.48
REMARK 500 PHE A 7 36.03 -89.34
REMARK 500 ARG A 21 48.02 85.21
REMARK 500 LYS A 27 178.91 61.80
REMARK 500 GLN A 33 37.38 -86.19
REMARK 500 LYS A 39 145.20 64.07
REMARK 500 ALA A 95 123.35 43.84
REMARK 500 THR A 103 102.12 68.64
REMARK 500 ASN A 109 92.46 52.92
REMARK 500 ASP A 129 30.08 -95.83
REMARK 500 VAL A 139 52.89 -118.44
REMARK 500 ASN A 140 -3.50 61.19
REMARK 500 LEU A 149 50.90 -96.02
REMARK 500 ASP A 150 -44.83 -147.79
REMARK 500 PRO A 152 -177.95 -68.89
REMARK 500 TYR A 155 13.28 57.12
REMARK 500 VAL A 158 113.96 69.05
REMARK 500 LYS A 167 -40.10 70.80
REMARK 500 PRO A 194 4.38 -67.85
REMARK 500 TRP A 195 144.44 67.38
REMARK 500 TYR A 202 -115.24 -86.98
REMARK 500 PHE A 203 -172.44 59.43
REMARK 500 GLU A 208 -63.92 -134.58
REMARK 500 ASP B 22 84.01 55.33
REMARK 500 SER B 51 86.99 -65.35
REMARK 500 LEU B 54 124.66 67.87
REMARK 500 LYS B 55 70.57 74.12
REMARK 500 SER B 60 58.91 -90.81
REMARK 500 LEU B 61 -45.59 -138.97
REMARK 500 GLU B 77 6.84 -68.08
REMARK 500 ASP B 89 -36.77 -131.56
REMARK 500 LYS B 94 -45.74 73.71
REMARK 500 HIS B 101 -61.42 -95.66
REMARK 500 TRP B 117 -29.71 74.99
REMARK 500 ALA B 147 76.70 -67.18
REMARK 500 ASN B 148 -33.59 178.81
REMARK 500 SER B 154 83.12 53.62
REMARK 500 GLN B 177 -22.72 65.86
REMARK 500 SER B 179 -179.51 68.49
REMARK 500 PRO B 190 42.75 -107.57
REMARK 500 GLU B 191 41.66 38.46
REMARK 500 LYS B 202 -8.09 -55.90
REMARK 500 LEU B 207 136.08 64.23
REMARK 500 LYS B 214 108.22 54.08
REMARK 500 PRO B 221 -94.79 -74.20
REMARK 500 LYS B 222 -88.95 -109.36
REMARK 500 PHE B 223 -62.38 -144.14
REMARK 500 ASP B 224 114.30 58.90
REMARK 500 THR C 44 138.72 67.50
REMARK 500
REMARK 500 THIS ENTRY HAS 654 RAMACHANDRAN OUTLIERS.
REMARK 500
REMARK 500 REMARK: NULL
REMARK 500
REMARK 500 GEOMETRY AND STEREOCHEMISTRY
REMARK 500 SUBTOPIC: NON-CIS, NON-TRANS
REMARK 500
REMARK 500 THE FOLLOWING PEPTIDE BONDS DEVIATE SIGNIFICANTLY FROM BOTH
REMARK 500 CIS AND TRANS CONFORMATION. CIS BONDS, IF ANY, ARE LISTED
REMARK 500 ON CISPEP RECORDS. TRANS IS DEFINED AS 180 +/- 30 AND
REMARK 500 CIS IS DEFINED AS 0 +/- 30 DEGREES.
REMARK 500 MODEL OMEGA
REMARK 500 THR F 191 ILE F 192 -148.30
REMARK 500 GLN X 63 PRO X 64 -139.66
REMARK 500 HIS Y 29 PRO Y 30 -143.91
REMARK 500 PHE l 158 ARG l 159 124.78
REMARK 500
REMARK 500 REMARK: NULL
REMARK 610
REMARK 610 MISSING HETEROATOM
REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER;
REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER;
REMARK 610 I=INSERTION CODE):
REMARK 610 M RES C SSEQI
REMARK 610 MET k 601
REMARK 620
REMARK 620 METAL COORDINATION
REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER;
REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE):
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21815 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 2 16 OP2
REMARK 620 2 G 2 16 OP1 58.2
REMARK 620 3 U 2 607 OP2 93.5 146.5
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21817 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U 2 27 O3'
REMARK 620 2 A 2 28 OP2 60.5
REMARK 620 3 A 2 28 OP1 56.1 70.3
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21821 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 47 OP2
REMARK 620 2 A 2 47 O5' 69.0
REMARK 620 3 A 2 47 OP1 62.5 56.5
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21835 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U 2 64 OP2
REMARK 620 2 U 2 64 OP1 60.2
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21828 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 2 99 O3'
REMARK 620 2 A 2 100 OP2 69.2
REMARK 620 3 C 2 360 OP2 162.5 93.4
REMARK 620 4 C 2 360 OP1 112.1 143.4 82.0
REMARK 620 5 C 2 360 O5' 116.7 144.3 77.0 70.0
REMARK 620 N 1 2 3 4
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21816 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 377 OP2
REMARK 620 2 U 2 378 OP2 89.8
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21814 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 399 O3'
REMARK 620 2 A 2 400 OP2 68.4
REMARK 620 3 A 2 400 OP1 59.9 67.9
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21802 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 2 401 O3'
REMARK 620 2 G 2 402 OP1 66.1
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21837 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 2 460 OP2
REMARK 620 2 G 2 460 OP1 80.4
REMARK 620 3 G 2 460 O5' 68.6 66.7
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21853 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 2 529 OP1
REMARK 620 2 C 2 530 OP2 104.9
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21803 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 554 OP2
REMARK 620 2 A 2 555 OP2 109.7
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21818 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 604 OP2
REMARK 620 2 A 2 604 OP1 83.1
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21823 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 618 OP2
REMARK 620 2 A 2 619 OP2 69.1
REMARK 620 3 A 2 620 OP2 131.2 87.0
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21805 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 2 623 OP2
REMARK 620 2 A 21024 OP2 109.6
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21850 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 2 760 OP2
REMARK 620 2 G 2 761 O6 99.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21840 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 2 984 O6
REMARK 620 2 G 2 985 O6 95.9
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21819 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U 21003 OP2
REMARK 620 2 U 21003 OP1 55.2
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21863 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 U 21008 OP1
REMARK 620 2 U 21008 O5' 56.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21874 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 21196 OP1
REMARK 620 2 C 21196 OP2 61.9
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21872 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 21199 OP2
REMARK 620 2 G 21200 OP1 69.1
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21880 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 21201 OP1
REMARK 620 2 A 21202 OP2 86.2
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21876 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 21273 OP2
REMARK 620 2 G 21426 OP1 104.4
REMARK 620 3 G 21426 OP2 81.5 89.7
REMARK 620 4 G 21426 O5' 135.7 60.3 58.8
REMARK 620 5 G 21427 OP2 126.6 97.6 147.3 97.5
REMARK 620 N 1 2 3 4
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21879 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 C 21273 OP1
REMARK 620 2 C 21273 OP2 69.9
REMARK 620 3 G 21426 OP1 113.9 102.8
REMARK 620 4 G 21426 OP2 127.3 63.2 58.3
REMARK 620 5 G 21427 OP2 138.2 132.7 96.1 92.7
REMARK 620 N 1 2 3 4
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21826 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 21327 OP2
REMARK 620 2 G 21327 O5' 73.5
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21878 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 21482 OP2
REMARK 620 2 U 21520 OP1 104.6
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21859 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 21539 OP2
REMARK 620 2 G 21540 OP2 85.4
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21822 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 21760 OP2
REMARK 620 2 A 21761 OP2 97.3
REMARK 620 3 G 21765 O2' 139.4 114.5
REMARK 620 4 G 21766 OP2 141.2 105.4 54.5
REMARK 620 N 1 2 3
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21812 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 A 21761 OP1
REMARK 620 2 U 21769 OP1 124.1
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG 21834 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 G 21790 O3'
REMARK 620 2 G 21791 OP2 57.8
REMARK 620 3 G 21791 O5' 56.8 72.4
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 ZN a 500 ZN
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 CYS a 23 SG
REMARK 620 2 CYS a 26 SG 101.2
REMARK 620 3 CYS a 77 SG 159.3 80.0
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 ZN b 101 ZN
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 CYS b 59 SG
REMARK 620 2 CYS b 59 O 88.3
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 ZN f 501 ZN
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 CYS f 121 SG
REMARK 620 2 CYS f 124 SG 108.1
REMARK 620 3 CYS f 139 SG 134.2 107.3
REMARK 620 N 1 2
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 MG k 602 MG
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 THR k 137 OG1
REMARK 620 2 GCP k 603 O1G 112.2
REMARK 620 N 1
REMARK 620
REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL
REMARK 620 ZN l 301 ZN
REMARK 620 N RES CSSEQI ATOM
REMARK 620 1 CYS l 262 SG
REMARK 620 2 SER l 264 OG 112.3
REMARK 620 N 1
REMARK 800
REMARK 800 SITE
REMARK 800 SITE_IDENTIFIER: AC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1801
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1802
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1803
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1804
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1805
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1806
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1807
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1808
REMARK 800
REMARK 800 SITE_IDENTIFIER: AC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1809
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1811
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1812
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1814
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1815
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1816
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1817
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1818
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1819
REMARK 800
REMARK 800 SITE_IDENTIFIER: BC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1821
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1822
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1823
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1824
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1825
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1826
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1827
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1828
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1829
REMARK 800
REMARK 800 SITE_IDENTIFIER: CC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1831
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1832
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1833
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1834
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1835
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1837
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1838
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1839
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1840
REMARK 800
REMARK 800 SITE_IDENTIFIER: DC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1841
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1842
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1843
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1846
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1847
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1848
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1850
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1852
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1853
REMARK 800
REMARK 800 SITE_IDENTIFIER: EC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1854
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1855
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1857
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1858
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1859
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1863
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1865
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1868
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1869
REMARK 800
REMARK 800 SITE_IDENTIFIER: FC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1870
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1871
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1872
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1873
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1874
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1875
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1876
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1877
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1878
REMARK 800
REMARK 800 SITE_IDENTIFIER: GC9
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1879
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC1
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG 2 1880
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC2
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN a 500
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC3
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN b 101
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC4
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN f 501
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC5
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MET k 601
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC6
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MG k 602
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC7
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE GCP k 603
REMARK 800
REMARK 800 SITE_IDENTIFIER: HC8
REMARK 800 EVIDENCE_CODE: SOFTWARE
REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE ZN l 301
REMARK 900
REMARK 900 RELATED ENTRIES
REMARK 900 RELATED ID: EMD-3048 RELATED DB: EMDB
REMARK 900 RELATED ID: EMD-3047 RELATED DB: EMDB
REMARK 900 RELATED ID: EMD-3049 RELATED DB: EMDB
REMARK 900 RELATED ID: 3J81 RELATED DB: PDB
REMARK 900 PY48S
REMARK 900 RELATED ID: 3JAM RELATED DB: PDB
REMARK 900 RELATED ID: 3JAQ RELATED DB: PDB
DBREF 3JAP A 1 254 UNP Q6CN12 RSSA_KLULA 1 254
DBREF 3JAP B 1 255 UNP Q6CWD0 RS3A_KLULA 1 255
DBREF 3JAP C 1 259 UNP Q6CKL3 Q6CKL3_KLULA 1 259
DBREF 3JAP D 1 237 UNP Q6CRK7 Q6CRK7_KLULA 1 237
DBREF 3JAP E 1 261 UNP Q6CWJ2 Q6CWJ2_KLULA 1 261
DBREF 3JAP F 1 227 UNP Q6CRA3 Q6CRA3_KLULA 1 227
DBREF 3JAP G 1 236 UNP Q6CM04 RS6_KLULA 1 236
DBREF 3JAP H 1 190 UNP Q6CTD6 Q6CTD6_KLULA 1 190
DBREF 3JAP I 1 201 UNP Q6CMG3 Q6CMG3_KLULA 1 201
DBREF 3JAP J 1 188 UNP Q6CM18 Q6CM18_KLULA 1 188
DBREF 3JAP K 1 106 UNP Q6CVZ5 Q6CVZ5_KLULA 1 106
DBREF 3JAP L 1 156 UNP Q6CX80 Q6CX80_KLULA 1 156
DBREF 3JAP M 1 134 UNP Q6CLU4 Q6CLU4_KLULA 1 134
DBREF 3JAP N 1 151 UNP Q6CJK0 Q6CJK0_KLULA 1 151
DBREF 3JAP O 1 137 UNP P27069 RS14_KLULA 1 137
DBREF 3JAP P 1 142 UNP Q6CKV4 Q6CKV4_KLULA 1 142
DBREF 3JAP Q 1 143 UNP Q875N2 RS16_KLULA 1 143
DBREF 3JAP R 1 136 UNP Q6CWU3 Q6CWU3_KLULA 1 136
DBREF 3JAP S 1 146 UNP Q6CWT9 Q6CWT9_KLULA 1 146
DBREF 3JAP T 1 144 UNP Q6CXM0 Q6CXM0_KLULA 1 144
DBREF 3JAP U 4 120 UNP Q6CIM1 Q6CIM1_KLULA 1 117
DBREF 3JAP V 1 87 UNP Q6CXT6 RS21_KLULA 1 87
DBREF 3JAP W 1 130 UNP Q6CW21 RS22_KLULA 1 130
DBREF 3JAP X 1 145 UNP F2Z602 F2Z602_KLULA 1 145
DBREF 3JAP Y 1 135 UNP Q6CU44 Q6CU44_KLULA 1 135
DBREF 3JAP Z 1 108 UNP Q6CW78 Q6CW78_KLULA 1 108
DBREF 3JAP a 1 119 UNP Q6CS01 Q6CS01_KLULA 1 119
DBREF 3JAP b 1 82 UNP Q6CNL2 Q6CNL2_KLULA 1 82
DBREF 3JAP c 1 67 UNP P33285 RS28_KLULA 1 67
DBREF 3JAP d 1 56 UNP Q6CPG3 RS29_KLULA 1 56
DBREF 3JAP e 1 63 UNP Q6CUH5 Q6CUH5_KLULA 1 63
DBREF 3JAP f 1 150 UNP P69061 RS27A_KLULA 1 150
DBREF 3JAP g 1 326 UNP Q6CNI7 Q6CNI7_KLULA 1 326
DBREF 3JAP h 1 25 UNP P0CX86 RL41A_YEAST 1 25
DBREF 3JAP i 1 153 UNP P38912 IF1A_YEAST 1 153
DBREF 3JAP j 1 304 UNP P20459 IF2A_YEAST 1 304
DBREF 3JAP k 1 527 UNP P32481 IF2G_YEAST 1 527
DBREF 3JAP l 1 285 UNP P09064 IF2B_YEAST 1 285
DBREF 3JAP m 1 108 UNP P32911 SUI1_YEAST 1 108
DBREF 3JAP o 1 495 UNP P38249 EIF3A_YEAST 1 495
DBREF 3JAP p 193 206 UNP P32497 EIF3C_YEAST 193 206
DBREF 3JAP p 251 812 UNP P32497 EIF3C_YEAST 251 812
DBREF 3JAP q 1 347 UNP P40217 EIF3I_YEAST 1 347
DBREF 3JAP r 704 734 UNP P06103 EIF3B_YEAST 704 734
DBREF 3JAP s 45 96 UNP A6ZZ25 EIF3G_YEAS7 45 96
DBREF 3JAP 1 1 76 PDB 3JAP 3JAP 1 76
DBREF 3JAP 2 1 1798 PDB 3JAP 3JAP 1 1798
DBREF 3JAP 3 0 24 PDB 3JAP 3JAP 0 24
DBREF 3JAP o 1 866 PDB 3JAP 3JAP 1 866
DBREF 3JAP p 20 812 PDB 3JAP 3JAP 20 812
SEQRES 1 1 75 A G C G C C G U G G C G C
SEQRES 2 1 75 A G U G G A A G C G C G C
SEQRES 3 1 75 A G G U C U C A U A A A C
SEQRES 4 1 75 C U G A U G U C C U C G G
SEQRES 5 1 75 A U C G A A A C C G A G C
SEQRES 6 1 75 G G C G C U A C C A
SEQRES 1 2 1781 U A U C U G G U U G A U C
SEQRES 2 2 1781 C U G C C A G U A G U C A
SEQRES 3 2 1781 U A U G C U U G U C U C A
SEQRES 4 2 1781 A A G A U U A A G C C A U
SEQRES 5 2 1781 G C A U G U C U A A G U A
SEQRES 6 2 1781 U A A G C A A U U U A U A
SEQRES 7 2 1781 C A G U G A A A C U G C G
SEQRES 8 2 1781 A A U G G C U C A U U A A
SEQRES 9 2 1781 A U C A G U U A U C G U U
SEQRES 10 2 1781 U A U U U G A U A G U U C
SEQRES 11 2 1781 C U U U A C U A C A U G G
SEQRES 12 2 1781 A U A U C U G U G G U A A
SEQRES 13 2 1781 U U C U A G A G C U A A U
SEQRES 14 2 1781 A C A U G C U U A A A A U
SEQRES 15 2 1781 C U C G A C C C U U U G G
SEQRES 16 2 1781 A A G A G A U G U A U U U
SEQRES 17 2 1781 A U U A G A U A A A A A A
SEQRES 18 2 1781 U C A A U G U C U U C G G
SEQRES 19 2 1781 A C U C C U U G A U G A U
SEQRES 20 2 1781 U C A U A A U A A C U U U
SEQRES 21 2 1781 U C G A A U C G C A U G G
SEQRES 22 2 1781 C C U U G U G C U G G C G
SEQRES 23 2 1781 A U G G U U C A U U C A A
SEQRES 24 2 1781 A U U U C U G C C C U A U
SEQRES 25 2 1781 C A A C U U U C G A U G G
SEQRES 26 2 1781 U A G G A U A G U G G C C
SEQRES 27 2 1781 U A C C A U G G U U U C A
SEQRES 28 2 1781 A C G G G U A A C G G G G
SEQRES 29 2 1781 A A U A A G G G U U C G A
SEQRES 30 2 1781 U U C C G G A G A G G G A
SEQRES 31 2 1781 G C C U G A G A A A C G G
SEQRES 32 2 1781 C U A C C A C A U C C A A
SEQRES 33 2 1781 G G A A G G C A G C A G G
SEQRES 34 2 1781 C G C G C A A A U U A C C
SEQRES 35 2 1781 C A A U C C U A A U U C A
SEQRES 36 2 1781 G G G A G G U A G U G A C
SEQRES 37 2 1781 A A U A A A U A A C G A U
SEQRES 38 2 1781 A C A G G G C C C A U U C
SEQRES 39 2 1781 G G G U C U U G U A A U U
SEQRES 40 2 1781 G G A A U G A G U A C A A
SEQRES 41 2 1781 U G U A A A U A C C U U A
SEQRES 42 2 1781 A C G A G G A A C A A C U
SEQRES 43 2 1781 G G A G G G C A A G U C U
SEQRES 44 2 1781 G G U G C C A G C A G C C
SEQRES 45 2 1781 G C G G U A A U U C C A G
SEQRES 46 2 1781 C U C C A G U A G C G U A
SEQRES 47 2 1781 U A U U A A A G U U G U U
SEQRES 48 2 1781 G C A G U U A A A A A G C
SEQRES 49 2 1781 U C G U A G U U G A A C U
SEQRES 50 2 1781 U U G G G U C U G G U U G
SEQRES 51 2 1781 U C C G G U C C G G U U U
SEQRES 52 2 1781 U U C A A C C G G A U C U
SEQRES 53 2 1781 U U C C U U C U G G C U A
SEQRES 54 2 1781 A C C U G U A C U C C U U
SEQRES 55 2 1781 G U G G G U G C A G G C G
SEQRES 56 2 1781 A A C C A G G A C U U U U
SEQRES 57 2 1781 A C U U U G A A A A A A U
SEQRES 58 2 1781 U A G A G U G U U C A A A
SEQRES 59 2 1781 G C A G G C G A A A G C U
SEQRES 60 2 1781 C G A A U A U A U U A G C
SEQRES 61 2 1781 A U G G A A U A A U G G A
SEQRES 62 2 1781 A U A G G A C G U U U G G
SEQRES 63 2 1781 U U C U A U U U U G U U G
SEQRES 64 2 1781 G U U U C U A G G A C C A
SEQRES 65 2 1781 U C G U A A U G A U U A A
SEQRES 66 2 1781 U A G G G A C G G U C G G
SEQRES 67 2 1781 G G G C A U C A G U A U U
SEQRES 68 2 1781 C A A U U G U C A G A G G
SEQRES 69 2 1781 U G A A A U U C U U G G A
SEQRES 70 2 1781 U U U A U U G A A G A C U
SEQRES 71 2 1781 A A C U A C U G C G A A A
SEQRES 72 2 1781 G C A U U U G C C A A G G
SEQRES 73 2 1781 A C G U U U U C A U U A A
SEQRES 74 2 1781 U C A A G A A C G A A A G
SEQRES 75 2 1781 U U A G G G G A U C G A A
SEQRES 76 2 1781 G A U G A U C A G A U A C
SEQRES 77 2 1781 C G U C G U A G U C U U A
SEQRES 78 2 1781 A C C A U A A A C U A U G
SEQRES 79 2 1781 C C G A C U A G G G A U C
SEQRES 80 2 1781 G G G U G G U G U U U U U
SEQRES 81 2 1781 C U U A U G A C C C A C U
SEQRES 82 2 1781 C G G C A C C U U A C G A
SEQRES 83 2 1781 G A A A U C A A A G U C U
SEQRES 84 2 1781 U U G G G U U C U G G G G
SEQRES 85 2 1781 G G A G U A U G G U C G C
SEQRES 86 2 1781 A A G G C U G A A A C U U
SEQRES 87 2 1781 A A A G G A A U U G A C G
SEQRES 88 2 1781 G A A G G G C A C C A C C
SEQRES 89 2 1781 A G G A G U G G A G C C U
SEQRES 90 2 1781 G C G G C U U A A U U U G
SEQRES 91 2 1781 A C U C A A C A C G G G G
SEQRES 92 2 1781 A A A C U C A C C A G G U
SEQRES 93 2 1781 C C A G A C A C A A U A A
SEQRES 94 2 1781 G G A U U G A C A G A U U
SEQRES 95 2 1781 G A G A G C U C U U U C U
SEQRES 96 2 1781 U G A U U U U G U G G G U
SEQRES 97 2 1781 G G U G G U G C A U G G C
SEQRES 98 2 1781 C G U U C U U A G U U G G
SEQRES 99 2 1781 U G G A G U G A U U U G U
SEQRES 100 2 1781 C U G C U U A A U U G C G
SEQRES 101 2 1781 A U A A C G A A C G A G A
SEQRES 102 2 1781 C C U U A A C C U A C U A
SEQRES 103 2 1781 A A U A G G G U U G C U G
SEQRES 104 2 1781 G C A C U U G C C G G U U
SEQRES 105 2 1781 G A C U C U U C U U A G A
SEQRES 106 2 1781 G G G A C U A U C G G U U
SEQRES 107 2 1781 U C A A G C C G A U G G A
SEQRES 108 2 1781 A G U U U G A G G C A A U
SEQRES 109 2 1781 A A C A G G U C U G U G A
SEQRES 110 2 1781 U G C C C U U A G A C G U
SEQRES 111 2 1781 U C U G G G C C G C A C G
SEQRES 112 2 1781 C G C G C U A C A C U G A
SEQRES 113 2 1781 C G G A G C C A G C G A G
SEQRES 114 2 1781 U A C A A C C U U G G C C
SEQRES 115 2 1781 G A G A G G U C U G G G U
SEQRES 116 2 1781 A A U C U U G U G A A A C
SEQRES 117 2 1781 U C C G U C G U G C U G G
SEQRES 118 2 1781 G G A U A G A G C A U U G
SEQRES 119 2 1781 U A A U U A U U G C U C U
SEQRES 120 2 1781 U C A A C G A G G A A U U
SEQRES 121 2 1781 C C U A G U A A G C G C A
SEQRES 122 2 1781 A G U C A U C A G C U U G
SEQRES 123 2 1781 C G U U G A U U A C G U C
SEQRES 124 2 1781 C C U G C C C U U U G U A
SEQRES 125 2 1781 C A C A C C G C C C G U C
SEQRES 126 2 1781 G C U A G U A C C G A U U
SEQRES 127 2 1781 G A A U G G C U U A G U G
SEQRES 128 2 1781 A G G C C U C A G G A U U
SEQRES 129 2 1781 U G C U U A G A G A A G G
SEQRES 130 2 1781 G G G C A A C U C C A U C
SEQRES 131 2 1781 U C A G A G C G A A G A A
SEQRES 132 2 1781 U C U G G U C A A A C U U
SEQRES 133 2 1781 G G U C A U U U A G A G G
SEQRES 134 2 1781 A A C U A A A A G U C G U
SEQRES 135 2 1781 A A C A A G G U U U C C G
SEQRES 136 2 1781 U A G G U G A A C C U G C
SEQRES 137 2 1781 G G A A G G A U C A U U A
SEQRES 1 3 25 G G A A U C U C U C U C U
SEQRES 2 3 25 A U G C U C U C U C U C
SEQRES 1 A 254 MET SER LEU PRO SER THR PHE ASP LEU THR SER GLU ASP
SEQRES 2 A 254 ALA GLN LEU LEU LEU ALA ALA ARG VAL HIS LEU GLY ALA
SEQRES 3 A 254 LYS ASN VAL GLN VAL HIS GLN GLU PRO TYR VAL TYR LYS
SEQRES 4 A 254 ALA ARG PRO ASP GLY VAL ASN VAL ILE ASN VAL GLY LYS
SEQRES 5 A 254 THR TRP GLU LYS ILE VAL LEU ALA ALA ARG ILE ILE ALA
SEQRES 6 A 254 ALA ILE PRO ASN PRO GLU ASP VAL VAL ALA ILE SER SER
SEQRES 7 A 254 ARG THR TYR GLY GLN ARG ALA VAL LEU LYS TYR ALA ALA
SEQRES 8 A 254 HIS THR GLY ALA THR PRO ILE ALA GLY ARG PHE THR PRO
SEQRES 9 A 254 GLY SER PHE THR ASN TYR ILE THR ARG SER PHE LYS GLU
SEQRES 10 A 254 PRO ARG LEU VAL ILE VAL THR ASP PRO ARG SER ASP ALA
SEQRES 11 A 254 GLN ALA ILE LYS GLU SER SER TYR VAL ASN ILE PRO VAL
SEQRES 12 A 254 ILE ALA LEU THR ASP LEU ASP SER PRO SER GLU TYR VAL
SEQRES 13 A 254 ASP VAL ALA ILE PRO CYS ASN ASN ARG GLY LYS HIS SER
SEQRES 14 A 254 ILE GLY LEU ILE TRP TYR LEU LEU ALA ARG GLU VAL LEU
SEQRES 15 A 254 ARG LEU ARG GLY ALA LEU PRO ASP ARG THR GLN PRO TRP
SEQRES 16 A 254 ALA ILE MET PRO ASP LEU TYR PHE TYR ARG ASN PRO GLU
SEQRES 17 A 254 GLU ILE GLU GLN GLN THR ALA GLU GLU GLU ALA VAL ALA
SEQRES 18 A 254 SER GLY GLU GLN THR GLU GLU ALA VAL ASP ALA THR GLU
SEQRES 19 A 254 GLU GLN THR GLU ALA ALA GLU TRP ALA GLU GLU GLY GLN
SEQRES 20 A 254 ALA GLN GLU GLU GLU TRP ASN
SEQRES 1 B 255 MET ALA VAL GLY LYS ASN LYS ARG LEU SER LYS GLY LYS
SEQRES 2 B 255 LYS GLY LEU LYS LYS ARG VAL VAL ASP PRO PHE THR ARG
SEQRES 3 B 255 LYS GLU TRP TYR ASP ILE LYS ALA PRO SER THR PHE GLU
SEQRES 4 B 255 ASN ARG ASN VAL GLY LYS THR LEU VAL ASN LYS SER VAL
SEQRES 5 B 255 GLY LEU LYS ASN ALA SER ASP SER LEU LYS GLY ARG VAL
SEQRES 6 B 255 VAL GLU VAL CYS LEU ALA ASP LEU GLN GLY SER GLU ASP
SEQRES 7 B 255 HIS SER PHE ARG LYS VAL LYS LEU ARG VAL ASP GLU VAL
SEQRES 8 B 255 GLN GLY LYS ASN LEU LEU THR ASN PHE HIS GLY MET ASP
SEQRES 9 B 255 PHE THR THR ASP LYS LEU ARG SER MET VAL ARG LYS TRP
SEQRES 10 B 255 GLN THR LEU ILE GLU ALA ASN VAL THR VAL LYS THR SER
SEQRES 11 B 255 ASP ASP TYR VAL LEU ARG ILE PHE ALA ILE ALA PHE THR
SEQRES 12 B 255 ARG LYS GLN ALA ASN GLN VAL LYS ARG THR SER TYR ALA
SEQRES 13 B 255 GLN SER SER HIS ILE ARG GLN ILE ARG LYS VAL ILE SER
SEQRES 14 B 255 GLU ILE LEU THR ARG GLU VAL GLN ASN SER THR LEU ALA
SEQRES 15 B 255 GLN LEU THR SER LYS LEU ILE PRO GLU VAL ILE ASN LYS
SEQRES 16 B 255 GLU ILE GLU ASN ALA THR LYS ASP ILE PHE PRO LEU GLN
SEQRES 17 B 255 ASN VAL HIS ILE ARG LYS VAL LYS LEU LEU LYS GLN PRO
SEQRES 18 B 255 LYS PHE ASP LEU GLY SER LEU LEU SER LEU HIS GLY GLU
SEQRES 19 B 255 ALA SER ALA GLU GLU LYS GLY LYS LYS VAL ALA GLY PHE
SEQRES 20 B 255 LYS ASP GLU ILE LEU GLU THR VAL
SEQRES 1 C 259 MET SER ALA PRO GLN ALA GLN GLY GLN GLN ALA PRO ARG
SEQRES 2 C 259 ARG GLY GLY PHE GLY GLY ALA ASN ARG GLY GLY ARG GLY
SEQRES 3 C 259 GLY ARG ARG GLY GLY ARG ARG ASP GLN GLU GLU LYS GLY
SEQRES 4 C 259 TRP VAL PRO VAL THR LYS LEU GLY ARG LEU VAL LYS ALA
SEQRES 5 C 259 GLY LYS ILE SER SER ILE GLU GLU ILE PHE LEU HIS SER
SEQRES 6 C 259 LEU PRO VAL LYS GLU PHE GLN ILE ILE ASP GLN LEU LEU
SEQRES 7 C 259 PRO ASN LEU LYS ASP GLU VAL MET ASN ILE LYS PRO VAL
SEQRES 8 C 259 GLN LYS GLN THR ARG ALA GLY GLN ARG THR ARG PHE LYS
SEQRES 9 C 259 ALA VAL VAL VAL VAL GLY ASP SER ASN GLY HIS VAL GLY
SEQRES 10 C 259 LEU GLY ILE LYS THR ALA LYS GLU VAL ALA GLY ALA ILE
SEQRES 11 C 259 ARG ALA GLY ILE ILE ILE ALA LYS LEU SER VAL ILE PRO
SEQRES 12 C 259 ILE ARG ARG GLY TYR TRP GLY THR ASN LEU GLY GLN PRO
SEQRES 13 C 259 HIS SER LEU ALA THR LYS THR SER GLY LYS CYS GLY SER
SEQRES 14 C 259 VAL SER VAL ARG LEU ILE PRO ALA PRO ARG GLY SER GLY
SEQRES 15 C 259 ILE VAL ALA SER PRO ALA VAL LYS LYS LEU MET GLN LEU
SEQRES 16 C 259 ALA GLY VAL GLU ASP VAL TYR THR SER SER THR GLY SER
SEQRES 17 C 259 THR ARG THR LEU GLU ASN THR LEU LYS ALA ALA PHE VAL
SEQRES 18 C 259 ALA ILE GLY ASN THR TYR GLY PHE LEU THR PRO ASN LEU
SEQRES 19 C 259 TRP GLU VAL GLN ALA LEU THR PRO SER PRO MET ASP VAL
SEQRES 20 C 259 TYR ALA ASP TYR ALA THR ALA SER LYS LYS LYS LEU
SEQRES 1 D 237 MET VAL ALA ILE ILE SER LYS LYS ARG LYS LEU VAL ALA
SEQRES 2 D 237 ASP GLY VAL PHE TYR ALA GLU LEU ASN GLU PHE PHE THR
SEQRES 3 D 237 ARG GLU LEU ALA GLU GLU GLY TYR SER GLY VAL GLU VAL
SEQRES 4 D 237 ARG VAL THR PRO THR LYS THR GLU ILE ILE ILE ARG ALA
SEQRES 5 D 237 THR LYS VAL GLN ASP VAL VAL GLY GLU ASN GLY ARG ARG
SEQRES 6 D 237 ILE ASN GLU LEU THR LEU LEU ILE GLU LYS ARG PHE LYS
SEQRES 7 D 237 TYR LYS ARG GLY THR ILE ALA LEU TYR ALA GLU ARG VAL
SEQRES 8 D 237 HIS ASP ARG GLY LEU SER ALA VAL ALA GLN ALA GLU SER
SEQRES 9 D 237 MET LYS PHE LYS LEU LEU ASN GLY LEU ALA ILE ARG ARG
SEQRES 10 D 237 ALA ALA TYR GLY VAL VAL ARG TYR VAL MET GLU SER GLY
SEQRES 11 D 237 ALA LYS GLY CYS GLU VAL VAL ILE SER GLY LYS LEU ARG
SEQRES 12 D 237 ALA ALA ARG ALA LYS SER MET LYS PHE ALA ASP GLY PHE
SEQRES 13 D 237 LEU ILE HIS SER GLY GLN PRO VAL ASN ASP PHE ILE GLU
SEQRES 14 D 237 THR ALA THR ARG HIS VAL LEU LEU ARG GLN GLY VAL LEU
SEQRES 15 D 237 GLY ILE LYS VAL LYS ILE MET LYS ASP PRO SER ARG ASN
SEQRES 16 D 237 THR SER GLY PRO LYS ALA LEU PRO ASP ALA VAL THR ILE
SEQRES 17 D 237 ILE GLU PRO LYS GLU GLU GLU PRO VAL LEU GLU PRO SER
SEQRES 18 D 237 VAL LYS ASP TYR ARG PRO THR GLU PRO VAL GLU ALA ALA
SEQRES 19 D 237 GLU SER ALA
SEQRES 1 E 261 MET ALA ARG GLY PRO LYS LYS HIS LEU LYS ARG LEU ALA
SEQRES 2 E 261 ALA PRO HIS HIS TRP MET LEU ASP LYS LEU SER GLY CYS
SEQRES 3 E 261 TYR ALA PRO ARG PRO SER ALA GLY PRO HIS LYS LEU ARG
SEQRES 4 E 261 GLU SER LEU PRO LEU ILE VAL PHE LEU ARG ASN ARG LEU
SEQRES 5 E 261 LYS TYR ALA LEU ASN GLY ARG GLU VAL LYS ALA ILE LEU
SEQRES 6 E 261 MET GLN ARG HIS VAL LYS VAL ASP GLY LYS VAL ARG THR
SEQRES 7 E 261 ASP THR THR PHE PRO ALA GLY PHE MET ASP VAL ILE THR
SEQRES 8 E 261 LEU GLU ALA THR ASN GLU ASN PHE ARG LEU VAL TYR ASP
SEQRES 9 E 261 VAL LYS GLY ARG PHE ALA VAL HIS ARG ILE THR ASP GLU
SEQRES 10 E 261 GLU ALA SER TYR LYS LEU ALA LYS VAL LYS LYS VAL GLN
SEQRES 11 E 261 LEU GLY LYS LYS GLY ILE PRO TYR VAL VAL THR HIS ASP
SEQRES 12 E 261 GLY ARG THR ILE ARG TYR PRO ASP PRO ASN ILE LYS VAL
SEQRES 13 E 261 ASN ASP THR VAL LYS VAL ASP LEU ALA THR GLY THR ILE
SEQRES 14 E 261 THR ASP PHE ILE LYS PHE ASP THR GLY LYS LEU VAL TYR
SEQRES 15 E 261 VAL THR GLY GLY ARG ASN LEU GLY ARG VAL GLY THR ILE
SEQRES 16 E 261 VAL HIS ARG GLU ARG HIS GLU GLY GLY PHE ASP LEU VAL
SEQRES 17 E 261 HIS ILE LYS ASP SER LEU GLU ASN THR PHE VAL THR ARG
SEQRES 18 E 261 LEU ASN ASN VAL PHE VAL ILE GLY GLU PRO GLY ARG PRO
SEQRES 19 E 261 TRP ILE SER LEU PRO LYS GLY LYS GLY ILE LYS LEU THR
SEQRES 20 E 261 ILE SER GLU GLU ARG ASP ARG ARG ARG ALA GLN HIS GLY
SEQRES 21 E 261 LEU
SEQRES 1 F 227 MET SER GLU HIS GLU ALA GLN VAL GLU VAL GLU VAL GLN
SEQRES 2 F 227 GLU ASP PHE GLU VAL VAL GLN GLU PHE VAL PRO VAL GLU
SEQRES 3 F 227 LEU ALA THR THR ILE PRO VAL GLU ILE GLN GLN ALA GLN
SEQRES 4 F 227 GLN GLU ILE LYS LEU PHE ASN LYS TRP SER PHE GLU ASP
SEQRES 5 F 227 VAL GLU VAL LYS ASP ALA SER LEU VAL ASP TYR ILE GLN
SEQRES 6 F 227 ILE SER LYS PRO ILE TYR VAL ALA HIS THR ALA GLY ARG
SEQRES 7 F 227 TYR ALA ASN LYS ARG PHE ARG LYS ALA GLN CYS PRO ILE
SEQRES 8 F 227 VAL GLU ARG LEU THR ASN SER LEU MET MET ASN GLY ARG
SEQRES 9 F 227 ASN ASN GLY LYS LYS LEU LYS ALA VAL ARG ILE VAL LYS
SEQRES 10 F 227 HIS THR LEU GLU ILE ILE ASN VAL LEU THR ASP GLN ASN
SEQRES 11 F 227 PRO LEU GLN VAL VAL VAL ASP ALA ILE ILE ASN SER GLY
SEQRES 12 F 227 PRO ARG GLU ASP THR THR ARG VAL GLY GLY GLY GLY ALA
SEQRES 13 F 227 ALA ARG ARG GLN ALA VAL ASP VAL SER PRO LEU ARG ARG
SEQRES 14 F 227 VAL ASN GLN SER ILE ALA LEU LEU THR ILE GLY ALA ARG
SEQRES 15 F 227 GLU ALA ALA PHE ARG ASN ILE LYS THR ILE ALA GLU THR
SEQRES 16 F 227 LEU ALA GLU GLU LEU ILE ASN ALA ALA LYS GLY SER SER
SEQRES 17 F 227 THR SER TYR ALA ILE LYS LYS LYS ASP GLU LEU GLU ARG
SEQRES 18 F 227 VAL ALA LYS SER ASN ARG
SEQRES 1 G 236 MET LYS LEU ASN ILE SER TYR PRO ILE ASN GLY THR GLN
SEQRES 2 G 236 LYS CYS ILE GLU ILE ASP ASP GLU HIS ARG VAL ARG VAL
SEQRES 3 G 236 PHE TYR ASP LYS ARG ILE GLY GLN GLU VAL ASP GLY GLU
SEQRES 4 G 236 SER VAL GLY ASP GLU PHE LYS GLY TYR VAL PHE LYS ILE
SEQRES 5 G 236 ALA GLY GLY ASN ASP LYS GLN GLY PHE PRO MET LYS GLN
SEQRES 6 G 236 GLY VAL LEU LEU PRO THR ARG VAL LYS LEU LEU LEU ALA
SEQRES 7 G 236 LYS GLY HIS SER CYS TYR ARG PRO ARG ARG ASN GLY GLU
SEQRES 8 G 236 ARG LYS ARG LYS SER VAL ARG GLY ALA ILE VAL GLY PRO
SEQRES 9 G 236 ASP LEU ALA VAL LEU ALA LEU ILE ILE THR LYS LYS GLY
SEQRES 10 G 236 GLU GLN GLU ILE GLU GLY ILE THR ASN ASP THR VAL PRO
SEQRES 11 G 236 LYS ARG LEU GLY PRO LYS ARG ALA ASN ASN ILE ARG LYS
SEQRES 12 G 236 PHE PHE GLY LEU THR LYS GLU ASP ASP VAL ARG ASP TYR
SEQRES 13 G 236 VAL ILE ARG ARG GLU VAL THR LYS GLY ASP LYS SER TYR
SEQRES 14 G 236 THR LYS ALA PRO LYS ILE GLN ARG LEU VAL THR PRO GLN
SEQRES 15 G 236 ARG LEU GLN ARG LYS ARG GLN GLN LYS SER LEU LYS ILE
SEQRES 16 G 236 LYS ASN ALA GLN ALA GLN ARG GLU ALA ALA ALA GLU TYR
SEQRES 17 G 236 ALA GLN LEU LEU ALA LYS ARG LEU SER GLU ARG LYS ALA
SEQRES 18 G 236 GLU LYS ALA GLU VAL ARG LYS ARG ARG ALA SER SER LEU
SEQRES 19 G 236 LYS ALA
SEQRES 1 H 190 MET SER ASP PRO GLN ALA LYS ILE LEU SER GLN ALA PRO
SEQRES 2 H 190 THR GLU LEU GLU LEU GLN VAL ALA GLN ALA PHE ILE ASP
SEQRES 3 H 190 LEU GLU ASN ASN SER PRO GLU LEU LYS ALA ASP LEU ARG
SEQRES 4 H 190 ALA LEU GLN PHE LYS SER ILE ARG GLU ILE GLU VAL ALA
SEQRES 5 H 190 GLY GLY LYS LYS ALA LEU ALA VAL PHE VAL PRO VAL PRO
SEQRES 6 H 190 SER LEU ALA ALA TYR HIS LYS VAL GLN ILE LYS LEU THR
SEQRES 7 H 190 ARG GLU LEU GLU LYS LYS PHE GLN ASP ARG HIS VAL ILE
SEQRES 8 H 190 PHE LEU ALA GLU ARG ARG ILE LEU PRO LYS PRO SER ARG
SEQRES 9 H 190 LYS SER ARG GLN THR GLN LYS ARG PRO ARG SER ARG THR
SEQRES 10 H 190 LEU THR ALA VAL HIS ASP LYS ILE LEU GLU ASP LEU VAL
SEQRES 11 H 190 PHE PRO THR GLU ILE VAL GLY LYS ARG VAL ARG TYR LEU
SEQRES 12 H 190 VAL GLY GLY ASN LYS ILE GLN LYS ILE LEU LEU ASN SER
SEQRES 13 H 190 LYS ASP VAL GLN HIS ILE ASP ASN LYS LEU GLU SER PHE
SEQRES 14 H 190 GLN ALA VAL TYR ASN LYS LEU THR GLY LYS GLN ILE VAL
SEQRES 15 H 190 PHE GLU ILE PRO SER GLU THR HIS
SEQRES 1 I 201 MET GLY ILE SER ARG ASP SER ARG HIS LYS ARG ALA ALA
SEQRES 2 I 201 THR GLY ALA LYS ARG ALA GLN PHE ARG LYS LYS ARG LYS
SEQRES 3 I 201 PHE GLU LEU GLY ARG GLN ALA ALA ASN THR LYS ILE GLY
SEQRES 4 I 201 THR LYS ARG ILE HIS PRO VAL ARG THR ARG GLY GLY ASN
SEQRES 5 I 201 GLN LYS PHE ARG ALA LEU ARG ILE GLU THR GLY ASN PHE
SEQRES 6 I 201 SER TRP ALA SER GLU GLY VAL ALA ARG LYS THR ARG ILE
SEQRES 7 I 201 THR GLY VAL VAL TYR HIS PRO SER ASN ASN GLU LEU VAL
SEQRES 8 I 201 ARG THR ASN THR LEU THR LYS ALA ALA ILE VAL GLN ILE
SEQRES 9 I 201 ASP ALA THR PRO PHE ARG GLN TRP TYR GLU SER HIS TYR
SEQRES 10 I 201 GLY GLN SER LEU GLY LYS LYS LYS ASN THR LYS ALA GLU
SEQRES 11 I 201 GLU GLU THR ALA THR THR SER LYS ASN THR GLU ARG LYS
SEQRES 12 I 201 TRP ALA ALA ARG ALA ALA GLU ALA LYS ILE GLU HIS ALA
SEQRES 13 I 201 VAL ASP SER GLN PHE GLY ALA GLY ARG LEU TYR ALA ALA
SEQRES 14 I 201 ILE SER SER ARG PRO GLY GLN SER GLY ARG CYS ASP GLY
SEQRES 15 I 201 TYR ILE LEU GLU GLY GLU GLU LEU ALA PHE TYR LEU ARG
SEQRES 16 I 201 ARG LEU THR ALA LYS LYS
SEQRES 1 J 188 MET PRO ARG ALA PRO ARG THR TYR SER LYS THR TYR SER
SEQRES 2 J 188 THR PRO LYS ARG PRO TYR GLU SER ALA ARG LEU ASP ALA
SEQRES 3 J 188 GLU LEU LYS LEU ALA GLY GLU TYR GLY LEU LYS ASN LYS
SEQRES 4 J 188 ARG GLU ILE TYR ARG ILE SER PHE GLN LEU SER LYS ILE
SEQRES 5 J 188 ARG ARG ALA ALA ARG ASP LEU LEU THR ARG ASP GLU LYS
SEQRES 6 J 188 ASP PRO LYS ARG LEU PHE GLU GLY ASN ALA LEU ILE ARG
SEQRES 7 J 188 ARG LEU VAL ARG ILE GLY VAL LEU SER GLU ASP LYS LYS
SEQRES 8 J 188 LYS LEU ASP TYR VAL LEU ALA LEU LYS VAL GLU ASP PHE
SEQRES 9 J 188 LEU GLU ARG ARG LEU GLN THR GLN VAL TYR LYS LEU GLY
SEQRES 10 J 188 LEU ALA LYS SER VAL HIS HIS ALA ARG VAL LEU ILE SER
SEQRES 11 J 188 GLN ARG HIS ILE ALA VAL GLY LYS GLN ILE VAL ASN ILE
SEQRES 12 J 188 PRO SER PHE MET VAL ARG LEU GLU SER GLU LYS HIS ILE
SEQRES 13 J 188 ASP PHE ALA ARG THR SER PRO PHE GLY GLY ALA ARG PRO
SEQRES 14 J 188 GLY ARG VAL ALA ARG LYS ARG ALA ALA ALA ALA GLY GLY
SEQRES 15 J 188 GLU GLU ALA ASP GLU GLU
SEQRES 1 K 106 MET LEU ILE PRO LYS GLU ASP ARG LYS LYS ILE TYR GLN
SEQRES 2 K 106 HIS LEU PHE GLN GLU GLY VAL LEU VAL ALA LYS LYS ASP
SEQRES 3 K 106 PHE ASN GLN PRO LYS HIS GLU GLU ILE ASP THR LYS ASN
SEQRES 4 K 106 LEU PHE VAL ILE LYS ALA LEU GLN SER LEU THR SER LYS
SEQRES 5 K 106 GLY PHE VAL LYS THR GLN PHE SER TRP GLN TYR TYR TYR
SEQRES 6 K 106 TYR THR LEU THR GLU GLU GLY VAL VAL TYR LEU ARG GLU
SEQRES 7 K 106 TYR LEU ASN LEU PRO GLU HIS ILE PHE PRO ALA THR TYR
SEQRES 8 K 106 LEU ALA GLY GLN SER GLY ASP GLN ARG PRO GLN GLY LYS
SEQRES 9 K 106 LYS TYR
SEQRES 1 L 156 MET SER THR GLU LEU THR VAL GLN SER GLU ARG ALA PHE
SEQRES 2 L 156 GLN LYS GLN PRO HIS ILE PHE THR ASN PRO LYS ALA LYS
SEQRES 3 L 156 ALA ASN ARG LYS THR LYS ARG TRP TYR LYS ASN VAL GLY
SEQRES 4 L 156 LEU GLY PHE LYS THR PRO LYS THR ALA ILE GLU GLY SER
SEQRES 5 L 156 TYR ILE ASP LYS LYS CYS PRO PHE THR GLY LEU VAL SER
SEQRES 6 L 156 ILE ARG GLY LYS ILE LEU THR GLY THR VAL VAL SER THR
SEQRES 7 L 156 ARG MET HIS ARG THR ILE VAL ILE ARG ARG ASP TYR LEU
SEQRES 8 L 156 HIS TYR VAL PRO LYS TYR ASN ARG TYR GLU LYS ARG HIS
SEQRES 9 L 156 LYS ASN VAL PRO ALA HIS VAL SER PRO ALA PHE ARG VAL
SEQRES 10 L 156 GLN VAL GLY ASP ILE VAL THR VAL GLY GLN CYS ARG PRO
SEQRES 11 L 156 ILE SER LYS THR VAL ARG PHE ASN VAL LEU LYS VAL ALA
SEQRES 12 L 156 SER ALA THR GLY LYS ALA ASN LYS GLN PHE ALA LYS PHE
SEQRES 1 M 134 MET SER ASP VAL GLU GLU VAL GLN GLN VAL PRO VAL ALA
SEQRES 2 M 134 GLU LEU THR ILE GLU ASP ALA LEU LYS VAL VAL LEU ARG
SEQRES 3 M 134 THR SER LEU VAL HIS ASP GLY LEU ALA ARG GLY LEU ARG
SEQRES 4 M 134 GLU SER ALA LYS ALA LEU THR ARG GLY GLU GLY GLN LEU
SEQRES 5 M 134 ALA VAL LEU VAL GLU SER VAL THR GLU GLU ALA ILE SER
SEQRES 6 M 134 LYS LEU VAL GLN GLY LEU ALA THR GLU ASN ASN VAL PRO
SEQRES 7 M 134 LEU ILE LYS VAL ALA ASP ALA LYS GLN LEU GLY GLU TRP
SEQRES 8 M 134 ALA GLY LEU GLY LYS ILE ASP ARG ASP GLY ASN ALA ARG
SEQRES 9 M 134 LYS VAL VAL GLY ALA SER VAL VAL VAL VAL LYS ASN TRP
SEQRES 10 M 134 GLY ALA ASP THR GLN GLU ARG GLU ILE LEU LEU GLU HIS
SEQRES 11 M 134 PHE SER GLN GLN
SEQRES 1 N 151 MET GLY ARG MET HIS SER LYS GLY LYS GLY MET SER SER
SEQRES 2 N 151 SER ALA ILE PRO TYR SER ARG ASN ALA PRO ALA TRP PHE
SEQRES 3 N 151 LYS GLY SER SER ASP GLY VAL VAL GLU GLN ILE ILE LYS
SEQRES 4 N 151 TYR ALA ARG LYS GLY LEU THR PRO SER GLN ILE GLY VAL
SEQRES 5 N 151 LEU LEU ARG ASP ALA HIS GLY VAL THR GLN ALA LYS VAL
SEQRES 6 N 151 ILE THR GLY ASN LYS ILE LEU ARG ILE LEU LYS SER ASN
SEQRES 7 N 151 GLY LEU ALA PRO GLU ILE PRO GLU ASP LEU TYR PHE LEU
SEQRES 8 N 151 ILE LYS LYS ALA VAL SER VAL ARG LYS HIS LEU GLU ARG
SEQRES 9 N 151 ASN ARG LYS ASP LYS ASP ALA LYS PHE ARG LEU ILE LEU
SEQRES 10 N 151 ILE GLU SER ARG ILE HIS ARG LEU ALA ARG TYR TYR ARG
SEQRES 11 N 151 THR VAL SER VAL LEU PRO PRO ASN TRP LYS TYR GLU SER
SEQRES 12 N 151 ALA THR ALA SER ALA LEU VAL ASN
SEQRES 1 O 137 MET ALA ASN VAL VAL GLN ALA LYS ASP ASN SER GLN VAL
SEQRES 2 O 137 PHE GLY VAL ALA ARG ILE PHE ALA SER PHE ASN ASP THR
SEQRES 3 O 137 PHE VAL HIS VAL THR ASP LEU SER GLY ARG GLU THR ILE
SEQRES 4 O 137 ALA ARG VAL THR GLY GLY MET LYS VAL LYS ALA ASP ARG
SEQRES 5 O 137 ASP GLU SER SER PRO TYR ALA ALA MET LEU ALA ALA GLN
SEQRES 6 O 137 ASP VAL ALA ALA LYS CYS LYS GLU VAL GLY ILE THR ALA
SEQRES 7 O 137 VAL HIS ILE LYS ILE ARG ALA THR GLY GLY THR ARG SER
SEQRES 8 O 137 LYS THR PRO GLY PRO GLY GLY GLN ALA ALA LEU ARG ALA
SEQRES 9 O 137 LEU ALA ARG SER GLY LEU ARG ILE GLY ARG ILE GLU ASP
SEQRES 10 O 137 VAL THR PRO VAL PRO SER ASP SER THR ARG LYS LYS GLY
SEQRES 11 O 137 GLY ARG ARG GLY ARG ARG LEU
SEQRES 1 P 142 MET SER GLU ALA ALA ALA PRO ARG LYS ARG SER PHE LYS
SEQRES 2 P 142 THR TYR SER TYR LYS GLY VAL ASP LEU GLU LYS LEU LEU
SEQRES 3 P 142 GLU MET PRO THR GLU ASP PHE VAL LYS LEU ALA PRO ALA
SEQRES 4 P 142 ARG VAL ARG ARG LYS PHE ALA ARG GLY LEU SER GLU LYS
SEQRES 5 P 142 PRO ALA GLY LEU MET LYS LYS LEU ARG ALA ALA LYS LEU
SEQRES 6 P 142 SER ALA PRO GLU ASN GLU LYS PRO ALA VAL VAL ARG THR
SEQRES 7 P 142 HIS LEU ARG ASN MET ILE ILE VAL PRO GLU MET ILE GLY
SEQRES 8 P 142 SER VAL VAL GLY VAL TYR ASN GLY LYS VAL PHE ASN GLN
SEQRES 9 P 142 VAL GLU ILE ARG PRO GLU MET VAL GLY HIS TYR LEU GLY
SEQRES 10 P 142 GLU PHE SER ILE THR TYR THR PRO VAL ARG HIS GLY ARG
SEQRES 11 P 142 ALA GLY ALA THR THR SER ARG PHE ILE PRO LEU ARG
SEQRES 1 Q 143 MET SER THR VAL PRO SER VAL GLN THR PHE GLY LYS LYS
SEQRES 2 Q 143 LYS SER ALA THR ALA VAL ALA HIS VAL LYS ALA GLY LYS
SEQRES 3 Q 143 GLY LEU ILE LYS VAL ASN GLY SER PRO ILE THR LEU VAL
SEQRES 4 Q 143 GLN PRO GLU ILE LEU ARG PHE LYS VAL TYR GLU PRO LEU
SEQRES 5 Q 143 LEU LEU VAL GLY LEU ASP LYS PHE ALA ASN ILE ASP ILE
SEQRES 6 Q 143 ARG VAL LYS VAL THR GLY GLY GLY HIS VAL SER GLN VAL
SEQRES 7 Q 143 TYR ALA ILE ARG GLN ALA ILE ALA LYS GLY LEU VAL ALA
SEQRES 8 Q 143 TYR HIS GLN LYS PHE VAL ASP GLU GLN SER LYS ASN GLU
SEQRES 9 Q 143 LEU LYS LYS ALA PHE THR SER TYR ASP ARG THR LEU LEU
SEQRES 10 Q 143 ILE ALA ASP SER ARG ARG PRO GLU PRO LYS LYS PHE GLY
SEQRES 11 Q 143 GLY ARG GLY ALA ARG SER ARG PHE GLN LYS SER TYR ARG
SEQRES 1 R 136 MET GLY ARG VAL ARG THR LYS THR VAL LYS ARG ALA SER
SEQRES 2 R 136 LYS ALA LEU ILE GLU LYS TYR TYR PRO LYS LEU THR MET
SEQRES 3 R 136 ASP PHE GLN THR ASN LYS ARG LEU CYS ASP GLU ILE ALA
SEQRES 4 R 136 THR ILE GLN SER LYS ARG LEU ARG ASN LYS ILE ALA GLY
SEQRES 5 R 136 TYR THR THR HIS LEU MET LYS ARG ILE GLN LYS GLY PRO
SEQRES 6 R 136 VAL ARG GLY ILE SER PHE LYS LEU GLN GLU GLU GLU ARG
SEQRES 7 R 136 GLU ARG LYS ASP GLN TYR VAL PRO ASP VAL SER ALA LEU
SEQRES 8 R 136 ASP LEU SER HIS SER ASN ASP VAL LEU ASN VAL ASP THR
SEQRES 9 R 136 GLN THR ALA GLU LEU VAL ASN SER LEU GLY LEU LYS LEU
SEQRES 10 R 136 PRO LEU SER VAL SER SER VAL SER ALA VAL ARG ASP ARG
SEQRES 11 R 136 ARG PHE ARG LYS ARG ASN
SEQRES 1 S 146 MET SER LEU VAL VAL GLN GLU GLN GLY SER PHE GLN HIS
SEQRES 2 S 146 ILE LEU ARG LEU LEU ASN THR ASN VAL ASP GLY ASN ILE
SEQRES 3 S 146 ASN VAL VAL TYR ALA LEU THR THR ILE ARG GLY VAL GLY
SEQRES 4 S 146 ARG ARG TYR ALA ASN LEU VAL CYS LYS LYS ALA ASP VAL
SEQRES 5 S 146 ASP LEU HIS LYS ARG ALA GLY GLU LEU THR GLN GLU GLU
SEQRES 6 S 146 LEU GLU ARG ILE VAL GLN ILE MET GLN ASN PRO THR HIS
SEQRES 7 S 146 TYR LYS ILE PRO ALA TRP PHE LEU ASN ARG GLN LYS ASP
SEQRES 8 S 146 VAL ASN ASP GLY LYS ASP TYR HIS SER LEU ALA ASN ASN
SEQRES 9 S 146 LEU GLU SER LYS LEU ARG ASP ASP LEU GLU ARG LEU LYS
SEQRES 10 S 146 LYS ILE ARG SER HIS ARG GLY ILE ARG HIS PHE TRP GLY
SEQRES 11 S 146 LEU ARG VAL ARG GLY GLN HIS THR LYS THR THR GLY ARG
SEQRES 12 S 146 ARG ARG ALA
SEQRES 1 T 144 MET PRO GLY VAL SER VAL ARG ASP VAL PRO ALA GLN ASP
SEQRES 2 T 144 PHE ILE ASN ASN TYR ALA SER PHE LEU GLN ARG GLN GLY
SEQRES 3 T 144 LYS LEU GLU VAL PRO GLY TYR VAL ASP ILE VAL LYS THR
SEQRES 4 T 144 SER ALA GLY ASN GLU LEU PRO PRO GLN ASP SER GLU GLY
SEQRES 5 T 144 TRP PHE TYR LYS ARG ALA ALA SER VAL ALA ARG HIS ILE
SEQRES 6 T 144 TYR LEU ARG LYS GLN VAL GLY VAL GLY LYS LEU ASN LYS
SEQRES 7 T 144 LEU TYR GLY GLY ALA LYS ASN ARG GLY VAL ARG PRO HIS
SEQRES 8 T 144 LYS HIS VAL ASP ALA SER GLY SER ILE ASN ARG LYS VAL
SEQRES 9 T 144 LEU GLN SER LEU GLU LYS LEU GLY VAL VAL GLU ILE SER
SEQRES 10 T 144 PRO LYS GLY GLY ARG ARG ILE SER ASP ASN GLY LEU ARG
SEQRES 11 T 144 ASP LEU ASP ARG ILE ALA ALA ALA THR LEU GLU ASP GLU
SEQRES 12 T 144 GLU
SEQRES 1 U 117 MET SER GLN VAL GLU LYS LYS SER GLU GLN GLN GLN GLU
SEQRES 2 U 117 VAL VAL ILE HIS LYS ILE ARG ILE ASN LEU THR SER THR
SEQRES 3 U 117 LYS VAL LYS GLN LEU GLU ASN VAL SER ALA ASN ILE ILE
SEQRES 4 U 117 LYS ASN ALA GLU THR PHE LYS LEU VAL LYS LYS GLY PRO
SEQRES 5 U 117 VAL ARG LEU PRO THR LYS VAL LEU LYS ILE SER THR ARG
SEQRES 6 U 117 LYS THR PRO ASN GLY GLU GLY SER LYS THR TRP ASP THR
SEQRES 7 U 117 TYR GLU MET ARG ILE HIS LYS ARG TYR ILE ASP LEU GLU
SEQRES 8 U 117 ALA PRO ALA HIS ILE VAL LYS ARG ILE THR GLN ILE THR
SEQRES 9 U 117 ILE GLU PRO GLY VAL ASP VAL GLU VAL ILE ILE ALA ALA
SEQRES 1 V 87 MET GLU ASN ASP LYS GLY GLN LEU VAL GLU LEU TYR VAL
SEQRES 2 V 87 PRO ARG LYS CYS SER ALA THR ASN ARG ILE ILE LYS ALA
SEQRES 3 V 87 LYS ASP HIS SER SER VAL GLN ILE ASN ILE ALA GLN VAL
SEQRES 4 V 87 ASP GLU GLU GLY ARG ALA ILE PRO GLY GLU TYR VAL THR
SEQRES 5 V 87 TYR ALA LEU SER GLY TYR ILE ARG ALA ARG GLY GLU ALA
SEQRES 6 V 87 ASP ASP SER LEU ASN ARG LEU ALA GLN GLN ASP GLY LEU
SEQRES 7 V 87 LEU LYS ASN VAL TRP SER TYR SER ARG
SEQRES 1 W 130 MET THR ARG THR SER VAL LEU ALA ASP ALA LEU ASN ALA
SEQRES 2 W 130 ILE ASN ASN ALA GLU LYS THR GLY LYS ARG GLN VAL LEU
SEQRES 3 W 130 ILE ARG PRO SER SER LYS VAL ILE ILE LYS PHE LEU GLN
SEQRES 4 W 130 VAL MET GLN LYS HIS GLY TYR ILE GLY GLU PHE GLU TYR
SEQRES 5 W 130 ILE ASP ASP HIS ARG SER GLY LYS ILE VAL VAL GLN LEU
SEQRES 6 W 130 ASN GLY ARG LEU ASN LYS CYS GLY VAL ILE SER PRO ARG
SEQRES 7 W 130 PHE ASN VAL LYS ILE ALA ASP VAL GLU LYS TRP THR ALA
SEQRES 8 W 130 ASN LEU LEU PRO ALA ARG GLN PHE GLY TYR VAL ILE LEU
SEQRES 9 W 130 THR THR SER ALA GLY ILE MET ASP HIS GLU GLU ALA HIS
SEQRES 10 W 130 ARG LYS HIS VAL SER GLY LYS ILE LEU GLY PHE VAL TYR
SEQRES 1 X 145 MET GLY LYS GLY LYS PRO ARG GLY LEU ASN SER ALA ARG
SEQRES 2 X 145 LYS LEU ARG VAL HIS ARG ARG ASN ASN ARG TRP ALA GLU
SEQRES 3 X 145 THR THR TYR LYS LYS ARG LEU LEU GLY THR ALA PHE LYS
SEQRES 4 X 145 SER SER PRO PHE GLY GLY SER SER HIS ALA LYS GLY ILE
SEQRES 5 X 145 VAL LEU GLU LYS ILE GLY ILE GLU SER LYS GLN PRO ASN
SEQRES 6 X 145 SER ALA ILE ARG LYS CYS VAL ARG VAL GLN LEU ILE LYS
SEQRES 7 X 145 ASN GLY LYS LYS VAL THR ALA PHE VAL PRO ASN ASP GLY
SEQRES 8 X 145 CYS LEU ASN PHE VAL ASP GLU ASN ASP GLU VAL LEU LEU
SEQRES 9 X 145 ALA GLY PHE GLY ARG LYS GLY LYS ALA LYS GLY ASP ILE
SEQRES 10 X 145 PRO GLY VAL ARG PHE LYS VAL VAL LYS VAL SER GLY VAL
SEQRES 11 X 145 SER LEU LEU ALA LEU TRP LYS GLU LYS LYS GLU LYS PRO
SEQRES 12 X 145 ARG SER
SEQRES 1 Y 135 MET SER ASP ALA ILE THR ILE ARG THR ARG LYS VAL ILE
SEQRES 2 Y 135 SER ASN PRO LEU LEU ALA ARG LYS GLN PHE VAL VAL ASP
SEQRES 3 Y 135 VAL LEU HIS PRO ASN ARG ALA ASN VAL SER LYS ASP GLU
SEQRES 4 Y 135 LEU ARG GLU LYS LEU ALA GLU ALA TYR LYS ALA GLU LYS
SEQRES 5 Y 135 ASP ALA VAL SER VAL PHE GLY PHE ARG THR GLN TYR GLY
SEQRES 6 Y 135 GLY GLY LYS SER THR GLY PHE GLY LEU VAL TYR ASN SER
SEQRES 7 Y 135 VAL ALA ASP ALA LYS LYS PHE GLU PRO ALA TYR ARG LEU
SEQRES 8 Y 135 VAL ARG TYR GLY LEU ALA GLU LYS VAL GLU LYS ALA SER
SEQRES 9 Y 135 ARG GLN GLN ARG LYS GLN ARG LYS ASN ARG GLY LYS LYS
SEQRES 10 Y 135 ILE PHE GLY THR GLY LYS SER ILE ALA LYS LYS ALA ALA
SEQRES 11 Y 135 ARG ARG ASN ALA ASP
SEQRES 1 Z 108 MET PRO PRO LYS GLN GLN LEU SER LYS ALA ALA LYS ALA
SEQRES 2 Z 108 ALA ALA ALA MET ALA GLY GLY LYS LYS SER LYS LYS LYS
SEQRES 3 Z 108 TRP SER LYS LYS SER HIS LYS ASP LYS ALA LYS HIS ALA
SEQRES 4 Z 108 VAL VAL LEU ASP GLN ASP LYS PHE ASP ARG ILE MET LYS
SEQRES 5 Z 108 GLU ALA PRO THR TYR ARG TYR VAL SER VAL SER VAL LEU
SEQRES 6 Z 108 VAL ASP ARG PHE LYS LEU GLY GLY SER LEU ALA ARG VAL
SEQRES 7 Z 108 ALA LEU ARG HIS LEU GLU ASN GLU GLY ILE ILE LYS PRO
SEQRES 8 Z 108 VAL SER LYS HIS SER LYS GLN ALA ILE TYR THR ARG ALA
SEQRES 9 Z 108 THR ALA SER GLU
SEQRES 1 a 119 MET PRO LYS LYS ARG ALA SER ASN GLY ARG ASN LYS LYS
SEQRES 2 a 119 GLY ARG GLY HIS VAL LYS PRO VAL ARG CYS VAL ASN CYS
SEQRES 3 a 119 SER ARG SER VAL PRO LYS ASP LYS ALA ILE LYS ARG MET
SEQRES 4 a 119 ALA ILE ARG ASN ILE VAL GLU ALA ALA ALA ILE ARG ASP
SEQRES 5 a 119 LEU SER GLU ALA SER VAL TYR ALA GLU TYR ALA LEU PRO
SEQRES 6 a 119 LYS THR TYR ASN LYS LEU HIS TYR CYS ILE SER CYS ALA
SEQRES 7 a 119 ILE HIS ALA ARG ILE VAL ARG VAL ARG SER ARG THR ASP
SEQRES 8 a 119 ARG ARG ILE ARG ALA PRO PRO GLN ARG PRO ARG PHE ASN
SEQRES 9 a 119 ARG ASP ASN LYS VAL SER PRO ALA ASP ALA ALA LYS LYS
SEQRES 10 a 119 ALA LEU
SEQRES 1 b 82 MET VAL LEU VAL GLN ASP LEU LEU HIS PRO THR ALA ALA
SEQRES 2 b 82 SER GLU ALA ARG LYS HIS LYS LEU LYS THR LEU VAL GLN
SEQRES 3 b 82 SER PRO ARG SER HIS PHE LEU ASP VAL LYS CYS PRO GLY
SEQRES 4 b 82 CYS LEU ASN ILE THR THR VAL PHE SER HIS ALA GLN THR
SEQRES 5 b 82 ALA VAL THR CYS GLU SER CYS SER THR VAL LEU CYS THR
SEQRES 6 b 82 PRO THR GLY GLY LYS ALA LYS LEU SER GLU GLY THR SER
SEQRES 7 b 82 PHE ARG ARG LYS
SEQRES 1 c 67 MET ASP THR LYS THR PRO VAL THR LEU ALA LYS VAL ILE
SEQRES 2 c 67 LYS VAL LEU GLY ARG THR GLY SER ARG GLY GLY VAL THR
SEQRES 3 c 67 GLN VAL ARG VAL GLU PHE LEU GLU ASP THR THR ARG THR
SEQRES 4 c 67 ILE VAL ARG ASN VAL LYS GLY PRO VAL ARG GLU GLY ASP
SEQRES 5 c 67 ILE LEU VAL LEU MET GLU SER GLU ARG GLU ALA ARG ARG
SEQRES 6 c 67 LEU ARG
SEQRES 1 d 56 MET ALA HIS GLU ASN VAL TRP TYR SER HIS PRO ARG LYS
SEQRES 2 d 56 PHE GLY LYS GLY SER ARG GLN CYS ARG ILE SER GLY SER
SEQRES 3 d 56 HIS SER GLY LEU ILE ARG LYS TYR GLY LEU ASN ILE ASP
SEQRES 4 d 56 ARG GLN SER PHE ARG GLU LYS ALA ASN ASP ILE GLY PHE
SEQRES 5 d 56 TYR LYS TYR ARG
SEQRES 1 e 63 MET GLY LYS VAL HIS GLY SER LEU ALA ARG ALA GLY LYS
SEQRES 2 e 63 VAL LYS SER GLN THR PRO LYS VAL GLU LYS GLN GLU LYS
SEQRES 3 e 63 PRO LYS GLN PRO LYS GLY ARG ALA TYR LYS ARG LEU LEU
SEQRES 4 e 63 TYR THR ARG ARG PHE VAL ASN VAL THR LEU THR ASN GLY
SEQRES 5 e 63 LYS ARG LYS MET ASN PRO SER PRO SER SER GLN
SEQRES 1 f 150 MET GLN ILE PHE VAL LYS THR LEU THR GLY LYS THR ILE
SEQRES 2 f 150 THR LEU GLU VAL GLU SER SER ASP THR ILE ASP ASN VAL
SEQRES 3 f 150 LYS SER LYS ILE GLN ASP LYS GLU GLY ILE PRO PRO ASP
SEQRES 4 f 150 GLN GLN ARG LEU ILE PHE ALA GLY LYS GLN LEU GLU ASP
SEQRES 5 f 150 GLY ARG THR LEU SER ASP TYR ASN ILE GLN LYS GLU SER
SEQRES 6 f 150 THR LEU HIS LEU VAL LEU ARG LEU ARG GLY GLY GLY LYS
SEQRES 7 f 150 LYS ARG LYS LYS LYS VAL TYR THR THR PRO LYS LYS ILE
SEQRES 8 f 150 ARG HIS LYS HIS LYS LYS VAL LYS LEU ALA VAL LEU ASN
SEQRES 9 f 150 TYR TYR LYS VAL ASP ASP GLU GLY LYS VAL ALA LYS LEU
SEQRES 10 f 150 ARG LYS GLU CYS PRO ASN CYS GLY PRO GLY ILE PHE LEU
SEQRES 11 f 150 ALA ASN HIS GLY ASP ARG PHE TYR CYS GLY LYS CYS HIS
SEQRES 12 f 150 SER THR PHE ALA THR GLN LYS
SEQRES 1 g 326 MET SER SER SER ASN ILE MET LEU VAL LEU ARG GLY THR
SEQRES 2 g 326 LEU GLU GLY HIS ASN GLY TRP VAL THR SER LEU SER THR
SEQRES 3 g 326 SER ALA ALA GLN PRO ASN LEU LEU VAL SER GLY SER ARG
SEQRES 4 g 326 ASP LYS THR LEU ILE SER TRP ARG LEU THR GLU ASN GLU
SEQRES 5 g 326 GLN GLN PHE GLY VAL PRO VAL ARG SER TYR LYS GLY HIS
SEQRES 6 g 326 SER HIS ILE VAL GLN ASP VAL VAL VAL SER ALA ASP GLY
SEQRES 7 g 326 ASN TYR ALA VAL SER ALA SER TRP ASP LYS THR LEU ARG
SEQRES 8 g 326 LEU TRP ASN LEU ALA THR GLY ASN SER GLU ALA ARG PHE
SEQRES 9 g 326 VAL GLY HIS THR GLY ASP VAL LEU SER VAL ALA ILE ASP
SEQRES 10 g 326 ALA ASN SER SER LYS ILE ILE SER ALA SER ARG ASP LYS
SEQRES 11 g 326 THR ILE ARG VAL TRP ASN THR VAL GLY ASP CYS ALA TYR
SEQRES 12 g 326 VAL LEU LEU GLY HIS THR ASP TRP VAL THR LYS VAL ARG
SEQRES 13 g 326 VAL ALA PRO LYS ASN LEU GLU ASP GLY GLU VAL ASP ASP
SEQRES 14 g 326 GLY ARG ILE THR PHE VAL SER ALA GLY MET ASP LYS ILE
SEQRES 15 g 326 VAL ARG SER TRP SER LEU ASN GLU ASP SER TYR ARG ILE
SEQRES 16 g 326 GLU ALA ASP PHE ILE GLY HIS ASN ASN TYR ILE ASN VAL
SEQRES 17 g 326 VAL GLN PRO SER PRO ASP GLY SER LEU ALA ALA SER ALA
SEQRES 18 g 326 GLY LYS ASP GLY GLN ILE TYR VAL TRP ASN LEU LYS HIS
SEQRES 19 g 326 LYS SER ALA PHE MET ASN PHE ASP ALA LYS ASP GLU VAL
SEQRES 20 g 326 PHE ALA LEU ALA PHE SER PRO SER ARG PHE TRP LEU THR
SEQRES 21 g 326 ALA ALA THR ALA SER GLY ILE LYS ILE TYR ASP LEU GLU
SEQRES 22 g 326 ASN GLU VAL LEU ILE ASP GLU LEU LYS PRO GLU PHE ALA
SEQRES 23 g 326 GLY TYR THR LYS ALA GLN ASP PRO HIS ALA VAL SER LEU
SEQRES 24 g 326 ALA TRP SER ALA ASP GLY GLN THR LEU PHE ALA GLY TYR
SEQRES 25 g 326 THR ASP ASN VAL ILE ARG VAL TRP GLN VAL MET THR ALA
SEQRES 26 g 326 ASN
SEQRES 1 h 25 MET ARG ALA LYS TRP ARG LYS LYS ARG THR ARG ARG LEU
SEQRES 2 h 25 LYS ARG LYS ARG ARG LYS VAL ARG ALA ARG SER LYS
SEQRES 1 i 153 MET GLY LYS LYS ASN THR LYS GLY GLY LYS LYS GLY ARG
SEQRES 2 i 153 ARG GLY LYS ASN ASP SER ASP GLY PRO LYS ARG GLU LEU
SEQRES 3 i 153 ILE TYR LYS GLU GLU GLY GLN GLU TYR ALA GLN ILE THR
SEQRES 4 i 153 LYS MET LEU GLY ASN GLY ARG VAL GLU ALA SER CYS PHE
SEQRES 5 i 153 ASP GLY ASN LYS ARG MET ALA HIS ILE ARG GLY LYS LEU
SEQRES 6 i 153 ARG LYS LYS VAL TRP MET GLY GLN GLY ASP ILE ILE LEU
SEQRES 7 i 153 VAL SER LEU ARG ASP PHE GLN ASP ASP GLN CYS ASP VAL
SEQRES 8 i 153 VAL HIS LYS TYR ASN LEU ASP GLU ALA ARG THR LEU LYS
SEQRES 9 i 153 ASN GLN GLY GLU LEU PRO GLU ASN ALA LYS ILE ASN GLU
SEQRES 10 i 153 THR ASP ASN PHE GLY PHE GLU SER ASP GLU ASP VAL ASN
SEQRES 11 i 153 PHE GLU PHE GLY ASN ALA ASP GLU ASP ASP GLU GLU GLY
SEQRES 12 i 153 GLU ASP GLU GLU LEU ASP ILE ASP ASP ILE
SEQRES 1 j 304 MET SER THR SER HIS CYS ARG PHE TYR GLU ASN LYS TYR
SEQRES 2 j 304 PRO GLU ILE ASP ASP ILE VAL MET VAL ASN VAL GLN GLN
SEQRES 3 j 304 ILE ALA GLU MET GLY ALA TYR VAL LYS LEU LEU GLU TYR
SEQRES 4 j 304 ASP ASN ILE GLU GLY MET ILE LEU LEU SER GLU LEU SER
SEQRES 5 j 304 ARG ARG ARG ILE ARG SER ILE GLN LYS LEU ILE ARG VAL
SEQRES 6 j 304 GLY LYS ASN ASP VAL ALA VAL VAL LEU ARG VAL ASP LYS
SEQRES 7 j 304 GLU LYS GLY TYR ILE ASP LEU SER LYS ARG ARG VAL SER
SEQRES 8 j 304 SER GLU ASP ILE ILE LYS CYS GLU GLU LYS TYR GLN LYS
SEQRES 9 j 304 SER LYS THR VAL HIS SER ILE LEU ARG TYR CYS ALA GLU
SEQRES 10 j 304 LYS PHE GLN ILE PRO LEU GLU GLU LEU TYR LYS THR ILE
SEQRES 11 j 304 ALA TRP PRO LEU SER ARG LYS PHE GLY HIS ALA TYR GLU
SEQRES 12 j 304 ALA PHE LYS LEU SER ILE ILE ASP GLU THR VAL TRP GLU
SEQRES 13 j 304 GLY ILE GLU PRO PRO SER LYS ASP VAL LEU ASP GLU LEU
SEQRES 14 j 304 LYS ASN TYR ILE SER LYS ARG LEU THR PRO GLN ALA VAL
SEQRES 15 j 304 LYS ILE ARG ALA ASP VAL GLU VAL SER CYS PHE SER TYR
SEQRES 16 j 304 GLU GLY ILE ASP ALA ILE LYS ASP ALA LEU LYS SER ALA
SEQRES 17 j 304 GLU ASP MET SER THR GLU GLN MET GLN VAL LYS VAL LYS
SEQRES 18 j 304 LEU VAL ALA ALA PRO LEU TYR VAL LEU THR THR GLN ALA
SEQRES 19 j 304 LEU ASP LYS GLN LYS GLY ILE GLU GLN LEU GLU SER ALA
SEQRES 20 j 304 ILE GLU LYS ILE THR GLU VAL ILE THR LYS TYR GLY GLY
SEQRES 21 j 304 VAL CYS ASN ILE THR MET PRO PRO LYS ALA VAL THR ALA
SEQRES 22 j 304 THR GLU ASP ALA GLU LEU GLN ALA LEU LEU GLU SER LYS
SEQRES 23 j 304 GLU LEU ASP ASN ARG SER ASP SER GLU ASP ASP GLU ASP
SEQRES 24 j 304 GLU SER ASP ASP GLU
SEQRES 1 k 527 MET SER ASP LEU GLN ASP GLN GLU PRO SER ILE ILE ILE
SEQRES 2 k 527 ASN GLY ASN LEU GLU PRO VAL GLY GLU PRO ASP ILE VAL
SEQRES 3 k 527 GLU GLU THR GLU VAL VAL ALA GLN GLU THR GLN GLU THR
SEQRES 4 k 527 GLN ASP ALA ASP LYS PRO LYS LYS LYS VAL ALA PHE THR
SEQRES 5 k 527 GLY LEU GLU GLU ASP GLY GLU THR GLU GLU GLU LYS ARG
SEQRES 6 k 527 LYS ARG GLU PHE GLU GLU GLY GLY GLY LEU PRO GLU GLN
SEQRES 7 k 527 PRO LEU ASN PRO ASP PHE SER LYS LEU ASN PRO LEU SER
SEQRES 8 k 527 ALA GLU ILE ILE ASN ARG GLN ALA THR ILE ASN ILE GLY
SEQRES 9 k 527 THR ILE GLY HIS VAL ALA HIS GLY LYS SER THR VAL VAL
SEQRES 10 k 527 ARG ALA ILE SER GLY VAL GLN THR VAL ARG PHE LYS ASP
SEQRES 11 k 527 GLU LEU GLU ARG ASN ILE THR ILE LYS LEU GLY TYR ALA
SEQRES 12 k 527 ASN ALA LYS ILE TYR LYS CYS GLN GLU PRO THR CYS PRO
SEQRES 13 k 527 GLU PRO ASP CYS TYR ARG SER PHE LYS SER ASP LYS GLU
SEQRES 14 k 527 ILE SER PRO LYS CYS GLN ARG PRO GLY CYS PRO GLY ARG
SEQRES 15 k 527 TYR LYS LEU VAL ARG HIS VAL SER PHE VAL ASP CYS PRO
SEQRES 16 k 527 GLY HIS ASP ILE LEU MET SER THR MET LEU SER GLY ALA
SEQRES 17 k 527 ALA VAL MET ASP ALA ALA LEU LEU LEU ILE ALA GLY ASN
SEQRES 18 k 527 GLU SER CYS PRO GLN PRO GLN THR SER GLU HIS LEU ALA
SEQRES 19 k 527 ALA ILE GLU ILE MET LYS LEU LYS HIS VAL ILE ILE LEU
SEQRES 20 k 527 GLN ASN LYS VAL ASP LEU MET ARG GLU GLU SER ALA LEU
SEQRES 21 k 527 GLU HIS GLN LYS SER ILE LEU LYS PHE ILE ARG GLY THR
SEQRES 22 k 527 ILE ALA ASP GLY ALA PRO ILE VAL PRO ILE SER ALA GLN
SEQRES 23 k 527 LEU LYS TYR ASN ILE ASP ALA VAL ASN GLU PHE ILE VAL
SEQRES 24 k 527 LYS THR ILE PRO VAL PRO PRO ARG ASP PHE MET ILE SER
SEQRES 25 k 527 PRO ARG LEU ILE VAL ILE ARG SER PHE ASP VAL ASN LYS
SEQRES 26 k 527 PRO GLY ALA GLU ILE GLU ASP LEU LYS GLY GLY VAL ALA
SEQRES 27 k 527 GLY GLY SER ILE LEU ASN GLY VAL PHE LYS LEU GLY ASP
SEQRES 28 k 527 GLU ILE GLU ILE ARG PRO GLY ILE VAL THR LYS ASP ASP
SEQRES 29 k 527 LYS GLY LYS ILE GLN CYS LYS PRO ILE PHE SER ASN ILE
SEQRES 30 k 527 VAL SER LEU PHE ALA GLU GLN ASN ASP LEU LYS PHE ALA
SEQRES 31 k 527 VAL PRO GLY GLY LEU ILE GLY VAL GLY THR LYS VAL ASP
SEQRES 32 k 527 PRO THR LEU CYS ARG ALA ASP ARG LEU VAL GLY GLN VAL
SEQRES 33 k 527 VAL GLY ALA LYS GLY HIS LEU PRO ASN ILE TYR THR ASP
SEQRES 34 k 527 ILE GLU ILE ASN TYR PHE LEU LEU ARG ARG LEU LEU GLY
SEQRES 35 k 527 VAL LYS THR ASP GLY GLN LYS GLN ALA LYS VAL ARG LYS
SEQRES 36 k 527 LEU GLU PRO ASN GLU VAL LEU MET VAL ASN ILE GLY SER
SEQRES 37 k 527 THR ALA THR GLY ALA ARG VAL VAL ALA VAL LYS ALA ASP
SEQRES 38 k 527 MET ALA ARG LEU GLN LEU THR SER PRO ALA CYS THR GLU
SEQRES 39 k 527 ILE ASN GLU LYS ILE ALA LEU SER ARG ARG ILE GLU LYS
SEQRES 40 k 527 HIS TRP ARG LEU ILE GLY TRP ALA THR ILE LYS LYS GLY
SEQRES 41 k 527 THR THR LEU GLU PRO ILE ALA
SEQRES 1 l 285 MET SER SER ASP LEU ALA ALA GLU LEU GLY PHE ASP PRO
SEQRES 2 l 285 ALA LEU LYS LYS LYS LYS LYS THR LYS LYS VAL ILE PRO
SEQRES 3 l 285 ASP ASP PHE ASP ALA ALA VAL ASN GLY LYS GLU ASN GLY
SEQRES 4 l 285 SER GLY ASP ASP LEU PHE ALA GLY LEU LYS LYS LYS LYS
SEQRES 5 l 285 LYS LYS SER LYS SER VAL SER ALA ASP ALA GLU ALA GLU
SEQRES 6 l 285 LYS GLU PRO THR ASP ASP ILE ALA GLU ALA LEU GLY GLU
SEQRES 7 l 285 LEU SER LEU LYS LYS LYS LYS LYS LYS THR LYS ASP SER
SEQRES 8 l 285 SER VAL ASP ALA PHE GLU LYS GLU LEU ALA LYS ALA GLY
SEQRES 9 l 285 LEU ASP ASN VAL ASP ALA GLU SER LYS GLU GLY THR PRO
SEQRES 10 l 285 SER ALA ASN SER SER ILE GLN GLN GLU VAL GLY LEU PRO
SEQRES 11 l 285 TYR SER GLU LEU LEU SER ARG PHE PHE ASN ILE LEU ARG
SEQRES 12 l 285 THR ASN ASN PRO GLU LEU ALA GLY ASP ARG SER GLY PRO
SEQRES 13 l 285 LYS PHE ARG ILE PRO PRO PRO VAL CYS LEU ARG ASP GLY
SEQRES 14 l 285 LYS LYS THR ILE PHE SER ASN ILE GLN ASP ILE ALA GLU
SEQRES 15 l 285 LYS LEU HIS ARG SER PRO GLU HIS LEU ILE GLN TYR LEU
SEQRES 16 l 285 PHE ALA GLU LEU GLY THR SER GLY SER VAL ASP GLY GLN
SEQRES 17 l 285 LYS ARG LEU VAL ILE LYS GLY LYS PHE GLN SER LYS GLN
SEQRES 18 l 285 MET GLU ASN VAL LEU ARG ARG TYR ILE LEU GLU TYR VAL
SEQRES 19 l 285 THR CYS LYS THR CYS LYS SER ILE ASN THR GLU LEU LYS
SEQRES 20 l 285 ARG GLU GLN SER ASN ARG LEU PHE PHE MET VAL CYS LYS
SEQRES 21 l 285 SER CYS GLY SER THR ARG SER VAL SER SER ILE LYS THR
SEQRES 22 l 285 GLY PHE GLN ALA THR VAL GLY LYS ARG ARG ARG MET
SEQRES 1 m 108 MET SER ILE GLU ASN LEU LYS SER PHE ASP PRO PHE ALA
SEQRES 2 m 108 ASP THR GLY ASP ASP GLU THR ALA THR SER ASN TYR ILE
SEQRES 3 m 108 HIS ILE ARG ILE GLN GLN ARG ASN GLY ARG LYS THR LEU
SEQRES 4 m 108 THR THR VAL GLN GLY VAL PRO GLU GLU TYR ASP LEU LYS
SEQRES 5 m 108 ARG ILE LEU LYS VAL LEU LYS LYS ASP PHE ALA CYS ASN
SEQRES 6 m 108 GLY ASN ILE VAL LYS ASP PRO GLU MET GLY GLU ILE ILE
SEQRES 7 m 108 GLN LEU GLN GLY ASP GLN ARG ALA LYS VAL CYS GLU PHE
SEQRES 8 m 108 MET ILE SER GLN LEU GLY LEU GLN LYS LYS ASN ILE LYS
SEQRES 9 m 108 ILE HIS GLY PHE
SEQRES 1 o 588 MET ALA PRO PRO PRO PHE ARG PRO GLU ASN ALA ILE LYS
SEQRES 2 o 588 ARG ALA ASP GLU LEU ILE SER VAL GLY GLU LYS GLN ALA
SEQRES 3 o 588 ALA LEU GLN SER LEU HIS ASP PHE ILE THR ALA ARG ARG
SEQRES 4 o 588 ILE ARG TRP ALA THR PRO SER THR VAL GLU PRO VAL VAL
SEQRES 5 o 588 PHE LYS PHE LEU GLU ILE GLY VAL GLU LEU LYS LYS GLY
SEQRES 6 o 588 LYS LEU LEU LYS ASP GLY LEU HIS GLN TYR LYS LYS LEU
SEQRES 7 o 588 ILE GLN GLY SER THR GLU GLY LEU VAL SER VAL GLY ALA
SEQRES 8 o 588 VAL ALA ARG LYS PHE ILE ASP LEU VAL GLU SER LYS ILE
SEQRES 9 o 588 ALA SER GLU GLN THR ARG ALA ASP GLU LEU GLN LYS GLN
SEQRES 10 o 588 GLU ILE ASP ASP ASP LEU GLU GLY GLY VAL THR PRO GLU
SEQRES 11 o 588 ASN LEU LEU ILE SER VAL TYR GLU SER ASP GLN SER VAL
SEQRES 12 o 588 ALA GLY PHE ASN ASP GLU ALA ILE THR SER TRP LEU ARG
SEQRES 13 o 588 PHE THR TRP GLU SER TYR ARG ALA VAL LEU ASP LEU LEU
SEQRES 14 o 588 ARG ASN ASN ALA LEU LEU GLU ILE THR TYR SER GLY VAL
SEQRES 15 o 588 VAL LYS LYS THR MET HIS PHE CYS LEU LYS TYR GLN ARG
SEQRES 16 o 588 LYS ASN GLU PHE LYS ARG LEU ALA GLU MET LEU ARG GLN
SEQRES 17 o 588 HIS LEU ASP ALA ALA ASN TYR GLN GLN SER LYS SER GLY
SEQRES 18 o 588 ASN ASN LEU VAL ASP LEU SER ASP ALA ASP THR LEU GLN
SEQRES 19 o 588 ARG TYR LEU ASP GLN ARG PHE GLN GLN VAL ASP VAL SER
SEQRES 20 o 588 VAL LYS LEU GLU LEU TRP HIS GLU ALA TYR ARG SER ILE
SEQRES 21 o 588 GLU ASP VAL PHE HIS LEU MET LYS ILE SER LYS ARG ALA
SEQRES 22 o 588 PRO LYS PRO SER THR LEU ALA ASN TYR TYR GLU ASN LEU
SEQRES 23 o 588 VAL LYS VAL PHE PHE VAL SER GLY ASP PRO LEU LEU HIS
SEQRES 24 o 588 THR THR ALA TRP LYS LYS PHE TYR LYS LEU TYR SER THR
SEQRES 25 o 588 ASN PRO ARG ALA THR GLU GLU GLU PHE LYS THR TYR SER
SEQRES 26 o 588 SER THR ILE PHE LEU SER ALA ILE SER THR GLN LEU ASP
SEQRES 27 o 588 GLU ILE PRO SER ILE GLY TYR ASP PRO HIS LEU ARG MET
SEQRES 28 o 588 TYR ARG LEU LEU ASN LEU ASP ALA LYS PRO THR ARG LYS
SEQRES 29 o 588 GLU MET LEU GLN SER ILE ILE GLU ASP GLU SER ILE TYR
SEQRES 30 o 588 GLY LYS VAL ASP GLU GLU LEU LYS GLU LEU TYR ASP ILE
SEQRES 31 o 588 ILE GLU VAL ASN PHE ASP VAL ASP THR VAL LYS GLN GLN
SEQRES 32 o 588 LEU GLU ASN LEU LEU VAL LYS LEU SER SER LYS THR TYR
SEQRES 33 o 588 PHE SER GLN TYR ILE ALA PRO LEU ARG ASP VAL ILE MET
SEQRES 34 o 588 ARG ARG VAL PHE VAL ALA ALA SER GLN LYS PHE THR THR
SEQRES 35 o 588 VAL SER GLN SER GLU LEU TYR LYS LEU ALA THR LEU PRO
SEQRES 36 o 588 ALA PRO LEU ASP LEU SER ALA TRP ASP ILE GLU LYS SER
SEQRES 37 o 588 LEU LEU GLN ALA ALA VAL GLU ASP TYR VAL SER ILE THR
SEQRES 38 o 588 ILE ASP HIS GLU SER ALA LYS VAL THR PHE ALA LYS ASP
SEQRES 39 o 588 PRO UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 40 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 41 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 42 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 43 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 44 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 45 o 588 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 46 o 588 UNK UNK UNK
SEQRES 1 p 652 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 2 p 652 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 3 p 652 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 4 p 652 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 5 p 652 UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK UNK
SEQRES 6 p 652 UNK UNK UNK ARG ALA TYR ASN THR THR LYS GLN ARG VAL
SEQRES 7 p 652 LYS LYS VAL SER UNK UNK UNK UNK UNK UNK UNK UNK GLN
SEQRES 8 p 652 GLU ASP PHE PHE THR ARG LEU GLN THR ILE ILE ASP SER
SEQRES 9 p 652 ARG GLY LYS LYS THR VAL ASN GLN GLN SER LEU ILE SER
SEQRES 10 p 652 THR LEU GLU GLU LEU LEU THR VAL ALA GLU LYS PRO TYR
SEQRES 11 p 652 GLU PHE ILE MET ALA TYR LEU THR LEU ILE PRO SER ARG
SEQRES 12 p 652 PHE ASP ALA SER ALA ASN LEU SER TYR GLN PRO ILE ASP
SEQRES 13 p 652 GLN TRP LYS SER SER PHE ASN ASP ILE SER LYS LEU LEU
SEQRES 14 p 652 SER ILE LEU ASP GLN THR ILE ASP THR TYR GLN VAL ASN
SEQRES 15 p 652 GLU PHE ALA ASP PRO ILE ASP PHE ILE GLU ASP GLU PRO
SEQRES 16 p 652 LYS GLU ASP SER ASP GLY VAL LYS ARG ILE LEU GLY SER
SEQRES 17 p 652 ILE PHE SER PHE VAL GLU ARG LEU ASP ASP GLU PHE MET
SEQRES 18 p 652 LYS SER LEU LEU ASN ILE ASP PRO HIS SER SER ASP TYR
SEQRES 19 p 652 LEU ILE ARG LEU ARG ASP GLU GLN SER ILE TYR ASN LEU
SEQRES 20 p 652 ILE LEU ARG THR GLN LEU TYR PHE GLU ALA THR LEU LYS
SEQRES 21 p 652 ASP GLU HIS ASP LEU GLU ARG ALA LEU THR ARG PRO PHE
SEQRES 22 p 652 VAL LYS ARG LEU ASP HIS ILE TYR TYR LYS SER GLU ASN
SEQRES 23 p 652 LEU ILE LYS ILE MET GLU THR ALA ALA TRP ASN ILE ILE
SEQRES 24 p 652 PRO ALA GLN PHE LYS SER LYS PHE THR SER LYS ASP GLN
SEQRES 25 p 652 LEU ASP SER ALA ASP TYR VAL ASP ASN LEU ILE ASP GLY
SEQRES 26 p 652 LEU SER THR ILE LEU SER LYS GLN ASN ASN ILE ALA VAL
SEQRES 27 p 652 GLN LYS ARG ALA ILE LEU TYR ASN ILE TYR TYR THR ALA
SEQRES 28 p 652 LEU ASN LYS ASP PHE GLN THR ALA LYS ASP MET LEU LEU
SEQRES 29 p 652 THR SER GLN VAL GLN THR ASN ILE ASN GLN PHE ASP SER
SEQRES 30 p 652 SER LEU GLN ILE LEU PHE ASN ARG VAL VAL VAL GLN LEU
SEQRES 31 p 652 GLY LEU SER ALA PHE LYS LEU CYS LEU ILE GLU GLU CYS
SEQRES 32 p 652 HIS GLN ILE LEU ASN ASP LEU LEU SER SER SER HIS LEU
SEQRES 33 p 652 ARG GLU ILE LEU GLY GLN GLN SER LEU HIS ARG ILE SER
SEQRES 34 p 652 LEU ASN SER SER ASN ASN ALA SER ALA ASP GLU ARG ALA
SEQRES 35 p 652 ARG GLN CYS LEU PRO TYR HIS GLN HIS ILE ASN LEU ASP
SEQRES 36 p 652 LEU ILE ASP VAL VAL PHE LEU THR CYS SER LEU LEU ILE
SEQRES 37 p 652 GLU ILE PRO ARG MET THR ALA PHE TYR SER GLY ILE LYS
SEQRES 38 p 652 VAL LYS ARG ILE PRO TYR SER PRO LYS SER ILE ARG ARG
SEQRES 39 p 652 SER LEU GLU HIS TYR ASP LYS LEU SER PHE GLN GLY PRO
SEQRES 40 p 652 PRO GLU THR LEU ARG ASP TYR VAL LEU PHE ALA ALA LYS
SEQRES 41 p 652 SER MET GLN LYS GLY ASN TRP ARG ASP SER VAL LYS TYR
SEQRES 42 p 652 LEU ARG GLU ILE LYS SER TRP ALA LEU LEU PRO ASN MET
SEQRES 43 p 652 GLU THR VAL LEU ASN SER LEU THR GLU ARG VAL GLN VAL
SEQRES 44 p 652 GLU SER LEU LYS THR TYR PHE PHE SER PHE LYS ARG PHE
SEQRES 45 p 652 TYR SER SER PHE SER VAL ALA LYS LEU ALA GLU LEU PHE
SEQRES 46 p 652 ASP LEU PRO GLU ASN LYS VAL VAL GLU VAL LEU GLN SER
SEQRES 47 p 652 VAL ILE ALA GLU LEU GLU ILE PRO ALA LYS LEU ASN ASP
SEQRES 48 p 652 GLU LYS THR ILE PHE VAL VAL GLU LYS GLY ASP GLU ILE
SEQRES 49 p 652 THR LYS LEU GLU GLU ALA MET VAL LYS LEU ASN LYS GLU
SEQRES 50 p 652 TYR LYS ILE ALA LYS GLU ARG LEU ASN PRO PRO SER ASN
SEQRES 51 p 652 ARG ARG
SEQRES 1 q 347 MET LYS ALA ILE LYS LEU THR GLY HIS GLU ARG PRO LEU
SEQRES 2 q 347 THR GLN VAL LYS TYR ASN LYS GLU GLY ASP LEU LEU PHE
SEQRES 3 q 347 SER CYS SER LYS ASP SER SER ALA SER VAL TRP TYR SER
SEQRES 4 q 347 LEU ASN GLY GLU ARG LEU GLY THR LEU ASP GLY HIS THR
SEQRES 5 q 347 GLY THR ILE TRP SER ILE ASP VAL ASP CYS PHE THR LYS
SEQRES 6 q 347 TYR CYS VAL THR GLY SER ALA ASP TYR SER ILE LYS LEU
SEQRES 7 q 347 TRP ASP VAL SER ASN GLY GLN CYS VAL ALA THR TRP LYS
SEQRES 8 q 347 SER PRO VAL PRO VAL LYS ARG VAL GLU PHE SER PRO CYS
SEQRES 9 q 347 GLY ASN TYR PHE LEU ALA ILE LEU ASP ASN VAL MET LYS
SEQRES 10 q 347 ASN PRO GLY SER ILE ASN ILE TYR GLU ILE GLU ARG ASP
SEQRES 11 q 347 SER ALA THR HIS GLU LEU THR LYS VAL SER GLU GLU PRO
SEQRES 12 q 347 ILE HIS LYS ILE ILE THR HIS GLU GLY LEU ASP ALA ALA
SEQRES 13 q 347 THR VAL ALA GLY TRP SER THR LYS GLY LYS TYR ILE ILE
SEQRES 14 q 347 ALA GLY HIS LYS ASP GLY LYS ILE SER LYS TYR ASP VAL
SEQRES 15 q 347 SER ASN ASN TYR GLU TYR VAL ASP SER ILE ASP LEU HIS
SEQRES 16 q 347 GLU LYS SER ILE SER ASP MET GLN PHE SER PRO ASP LEU
SEQRES 17 q 347 THR TYR PHE ILE THR SER SER ARG ASP THR ASN SER PHE
SEQRES 18 q 347 LEU VAL ASP VAL SER THR LEU GLN VAL LEU LYS LYS TYR
SEQRES 19 q 347 GLU THR ASP CYS PRO LEU ASN THR ALA VAL ILE THR PRO
SEQRES 20 q 347 LEU LYS GLU PHE ILE ILE LEU GLY GLY GLY GLN GLU ALA
SEQRES 21 q 347 LYS ASP VAL THR THR THR SER ALA ASN GLU GLY LYS PHE
SEQRES 22 q 347 GLU ALA ARG PHE TYR HIS LYS ILE PHE GLU GLU GLU ILE
SEQRES 23 q 347 GLY ARG VAL GLN GLY HIS PHE GLY PRO LEU ASN THR VAL
SEQRES 24 q 347 ALA ILE SER PRO GLN GLY THR SER TYR ALA SER GLY GLY
SEQRES 25 q 347 GLU ASP GLY PHE ILE ARG LEU HIS HIS PHE GLU LYS SER
SEQRES 26 q 347 TYR PHE ASP PHE LYS TYR ASP VAL GLU LYS ALA ALA GLU
SEQRES 27 q 347 ALA LYS GLU HIS MET GLN GLU ALA ASN
SEQRES 1 r 31 LEU HIS GLN ARG GLU LEU LEU LYS GLN TRP THR GLU TYR
SEQRES 2 r 31 ARG GLU LYS ILE GLY GLN GLU MET GLU LYS SER MET ASN
SEQRES 3 r 31 PHE LYS ILE PHE ASP
SEQRES 1 s 52 VAL HIS LYS SER VAL ALA GLU ARG LYS ASN TRP HIS LYS
SEQRES 2 s 52 TYR GLY SER GLU LYS GLY SER PRO ALA GLY PRO SER ALA
SEQRES 3 s 52 VAL THR ALA ARG LEU GLY GLU GLU VAL GLU LEU ARG LEU
SEQRES 4 s 52 SER ARG ASN TRP LYS GLN ALA GLU GLU GLU ARG ILE GLN
HET MG 21801 1
HET MG 21802 1
HET MG 21803 1
HET MG 21804 1
HET MG 21805 1
HET MG 21806 1
HET MG 21807 1
HET MG 21808 1
HET MG 21809 1
HET MG 21810 1
HET MG 21811 1
HET MG 21812 1
HET MG 21813 1
HET MG 21814 1
HET MG 21815 1
HET MG 21816 1
HET MG 21817 1
HET MG 21818 1
HET MG 21819 1
HET MG 21820 1
HET MG 21821 1
HET MG 21822 1
HET MG 21823 1
HET MG 21824 1
HET MG 21825 1
HET MG 21826 1
HET MG 21827 1
HET MG 21828 1
HET MG 21829 1
HET MG 21830 1
HET MG 21831 1
HET MG 21832 1
HET MG 21833 1
HET MG 21834 1
HET MG 21835 1
HET MG 21836 1
HET MG 21837 1
HET MG 21838 1
HET MG 21839 1
HET MG 21840 1
HET MG 21841 1
HET MG 21842 1
HET MG 21843 1
HET MG 21844 1
HET MG 21845 1
HET MG 21846 1
HET MG 21847 1
HET MG 21848 1
HET MG 21849 1
HET MG 21850 1
HET MG 21851 1
HET MG 21852 1
HET MG 21853 1
HET MG 21854 1
HET MG 21855 1
HET MG 21856 1
HET MG 21857 1
HET MG 21858 1
HET MG 21859 1
HET MG 21860 1
HET MG 21861 1
HET MG 21862 1
HET MG 21863 1
HET MG 21864 1
HET MG 21865 1
HET MG 21866 1
HET MG 21867 1
HET MG 21868 1
HET MG 21869 1
HET MG 21870 1
HET MG 21871 1
HET MG 21872 1
HET MG 21873 1
HET MG 21874 1
HET MG 21875 1
HET MG 21876 1
HET MG 21877 1
HET MG 21878 1
HET MG 21879 1
HET MG 21880 1
HET ZN a 500 1
HET ZN b 101 1
HET ZN f 501 1
HET MET k 601 8
HET MG k 602 1
HET GCP k 603 32
HET ZN l 301 1
HETNAM MG MAGNESIUM ION
HETNAM ZN ZINC ION
HETNAM MET METHIONINE
HETNAM GCP PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
FORMUL 48 MG 81(MG 2+)
FORMUL 28 ZN 4(ZN 2+)
FORMUL 31 MET C5 H11 N O2 S
FORMUL 33 GCP C11 H18 N5 O13 P3
HELIX 1 1 THR A 10 ARG A 21 1 12
HELIX 2 2 ASN A 49 ILE A 67 1 19
HELIX 3 3 ARG A 79 TYR A 81 5 3
HELIX 4 4 GLY A 82 THR A 93 1 12
HELIX 5 5 ASP A 129 VAL A 139 1 11
HELIX 6 6 HIS A 168 GLY A 186 1 19
HELIX 7 7 MET A 198 TYR A 202 5 5
HELIX 8 8 PRO B 23 THR B 25 5 3
HELIX 9 9 SER B 76 SER B 80 5 5
HELIX 10 10 THR B 106 VAL B 114 1 9
HELIX 11 11 GLN B 157 VAL B 176 1 20
HELIX 12 12 THR B 180 ILE B 189 1 10
HELIX 13 13 GLU B 191 LYS B 202 1 12
HELIX 14 14 LEU B 225 LEU B 231 1 7
HELIX 15 15 THR C 44 GLY C 53 1 10
HELIX 16 16 SER C 57 SER C 65 1 9
HELIX 17 17 PHE C 71 LEU C 78 1 8
HELIX 18 18 GLU C 125 VAL C 141 1 17
HELIX 19 19 SER C 186 GLY C 197 1 12
HELIX 20 20 THR C 211 ASN C 225 1 15
HELIX 21 21 SER C 243 TYR C 248 1 6
HELIX 22 22 SER D 6 LEU D 29 1 24
HELIX 23 23 VAL D 55 GLY D 60 1 6
HELIX 24 24 GLY D 63 LYS D 78 1 16
HELIX 25 25 SER D 97 GLY D 112 1 16
HELIX 26 26 ALA D 114 GLY D 130 1 17
HELIX 27 27 GLY D 161 ASN D 165 5 5
HELIX 28 28 ASP D 191 THR D 196 1 6
HELIX 29 29 PRO E 15 MET E 19 5 5
HELIX 30 30 PRO E 43 ASN E 50 1 8
HELIX 31 31 ASN E 57 GLN E 67 1 11
HELIX 32 32 THR E 115 SER E 120 1 6
HELIX 33 33 LYS E 133 GLY E 135 5 3
HELIX 34 34 GLY E 185 LEU E 189 5 5
HELIX 35 35 THR E 247 GLN E 258 1 12
HELIX 36 36 PRO F 32 GLN F 37 1 6
HELIX 37 37 GLN F 37 ILE F 42 1 6
HELIX 38 38 PHE F 84 CYS F 89 5 6
HELIX 39 39 PRO F 90 MET F 100 1 11
HELIX 40 40 LYS F 108 LEU F 126 1 19
HELIX 41 41 ASN F 130 GLY F 143 1 14
HELIX 42 42 SER F 165 PHE F 186 1 22
HELIX 43 43 THR F 191 LYS F 205 1 15
HELIX 44 44 SER F 210 ASN F 226 1 17
HELIX 45 45 ASP G 20 ARG G 25 1 6
HELIX 46 46 GLY G 38 GLY G 42 1 5
HELIX 47 47 GLN G 59 PHE G 61 5 3
HELIX 48 48 ARG G 137 GLY G 146 1 10
HELIX 49 49 THR G 180 GLU G 222 1 43
HELIX 50 50 GLN H 5 LEU H 9 5 5
HELIX 51 51 THR H 14 GLU H 28 1 15
HELIX 52 52 ASN H 29 SER H 31 5 3
HELIX 53 53 ASP H 37 LEU H 41 5 5
HELIX 54 54 SER H 66 GLN H 74 1 9
HELIX 55 55 GLN H 74 PHE H 85 1 12
HELIX 56 56 THR H 117 VAL H 130 1 14
HELIX 57 57 ASP H 158 ILE H 162 5 5
HELIX 58 58 LYS H 165 THR H 177 1 13
HELIX 59 59 ARG I 25 PHE I 27 5 3
HELIX 60 60 ASN I 87 ASN I 94 1 8
HELIX 61 61 ALA I 106 TYR I 117 1 12
HELIX 62 62 SER I 137 ALA I 148 1 12
HELIX 63 63 GLU I 154 GLY I 164 1 11
HELIX 64 64 ARG I 173 GLY I 178 1 6
HELIX 65 65 GLY I 187 LYS I 201 1 15
HELIX 66 66 GLU J 20 GLY J 35 1 16
HELIX 67 67 ASN J 38 ARG J 62 1 25
HELIX 68 68 ASP J 66 GLY J 84 1 19
HELIX 69 69 VAL J 101 ARG J 107 1 7
HELIX 70 70 ARG J 108 LYS J 115 1 8
HELIX 71 71 SER J 121 GLN J 131 1 11
HELIX 72 72 ARG J 149 ILE J 156 5 8
HELIX 73 73 ARG J 171 GLY J 182 1 12
HELIX 74 74 PRO K 4 GLY K 19 1 16
HELIX 75 75 LYS K 38 GLY K 53 1 16
HELIX 76 76 THR K 69 ASN K 81 1 13
HELIX 77 77 PRO L 45 GLY L 51 1 7
HELIX 78 78 GLU M 18 ASP M 32 1 15
HELIX 79 79 LEU M 38 ARG M 47 1 10
HELIX 80 80 GLU M 62 GLU M 74 1 13
HELIX 81 81 ASP M 84 GLY M 93 1 10
HELIX 82 82 GLU M 123 SER M 132 1 10
HELIX 83 83 SER N 29 GLY N 44 1 16
HELIX 84 84 THR N 46 HIS N 58 1 13
HELIX 85 85 GLN N 62 THR N 67 1 6
HELIX 86 86 LYS N 70 GLY N 79 1 10
HELIX 87 87 PRO N 85 ASN N 105 1 21
HELIX 88 88 LYS N 109 SER N 133 1 25
HELIX 89 89 SER N 143 ASN N 151 1 9
HELIX 90 90 THR O 43 VAL O 48 1 6
HELIX 91 91 ALA O 50 SER O 55 5 6
HELIX 92 92 SER O 56 GLY O 75 1 20
HELIX 93 93 GLY O 97 ARG O 107 1 11
HELIX 94 94 GLU P 23 GLU P 27 5 5
HELIX 95 95 PRO P 29 LEU P 36 1 8
HELIX 96 96 PRO P 38 ARG P 47 1 10
HELIX 97 97 GLY P 55 ALA P 67 1 13
HELIX 98 98 TYR P 115 PHE P 119 5 5
HELIX 99 99 LEU Q 44 GLY Q 56 1 13
HELIX 100 100 LEU Q 57 ALA Q 61 5 5
HELIX 101 101 HIS Q 74 VAL Q 97 1 24
HELIX 102 102 ASP Q 98 THR Q 110 1 13
HELIX 103 103 THR R 6 TYR R 20 1 15
HELIX 104 104 ASP R 27 ALA R 39 1 13
HELIX 105 105 LYS R 44 GLY R 64 1 21
HELIX 106 106 PHE R 71 GLU R 79 1 9
HELIX 107 107 ASP R 103 LEU R 113 1 11
HELIX 108 108 ARG S 16 THR S 20 5 5
HELIX 109 109 VAL S 28 THR S 33 1 6
HELIX 110 110 GLY S 39 ASP S 51 1 13
HELIX 111 111 THR S 62 ASN S 75 1 14
HELIX 112 112 ASN S 104 ILE S 119 1 16
HELIX 113 113 SER S 121 GLY S 130 1 10
HELIX 114 114 SER T 5 VAL T 9 5 5
HELIX 115 115 ALA T 11 GLN T 25 1 15
HELIX 116 116 TRP T 53 ARG T 68 1 16
HELIX 117 117 GLY T 72 TYR T 80 1 9
HELIX 118 118 SER T 97 GLY T 112 1 16
HELIX 119 119 SER T 125 GLU T 144 1 20
HELIX 120 120 VAL U 31 LYS U 49 1 19
HELIX 121 121 ALA U 97 GLN U 105 1 9
HELIX 122 122 SER V 56 GLY V 63 1 8
HELIX 123 123 GLU V 64 ASP V 76 1 13
HELIX 124 124 SER W 5 GLY W 21 1 17
HELIX 125 125 SER W 31 GLY W 45 1 15
HELIX 126 126 ALA W 84 LEU W 94 1 11
HELIX 127 127 HIS W 113 HIS W 120 1 8
HELIX 128 128 ALA X 12 TRP X 24 1 13
HELIX 129 129 GLU X 26 LEU X 34 1 9
HELIX 130 130 GLY X 35 SER X 40 1 6
HELIX 131 131 CYS X 92 ASP X 97 1 6
HELIX 132 132 LEU X 132 GLU X 138 1 7
HELIX 133 133 SER Y 36 GLU Y 46 1 11
HELIX 134 134 GLU Y 51 ASP Y 53 5 3
HELIX 135 135 SER Y 78 LYS Y 84 1 7
HELIX 136 136 PRO Y 87 GLY Y 95 1 9
HELIX 137 137 SER Y 104 ILE Y 118 1 15
HELIX 138 138 GLY Y 122 ASP Y 135 1 14
HELIX 139 139 ASP Z 43 ALA Z 54 1 12
HELIX 140 140 SER Z 61 ARG Z 68 1 8
HELIX 141 141 GLY Z 73 GLU Z 84 1 12
HELIX 142 142 ALA a 49 SER a 57 1 9
HELIX 143 143 CYS a 74 ARG a 82 1 9
HELIX 144 144 THR b 11 LYS b 18 1 8
HELIX 145 145 ARG d 32 LEU d 36 5 5
HELIX 146 146 ARG d 40 ALA d 47 1 8
HELIX 147 147 ASN d 48 ILE d 50 5 3
HELIX 148 148 GLY e 12 THR e 18 1 7
HELIX 149 149 GLY e 32 VAL e 45 1 14
HELIX 150 150 ARG h 2 LYS h 25 1 24
HELIX 151 151 LYS i 11 GLY i 15 5 5
HELIX 152 152 ASN i 96 GLY i 107 1 12
HELIX 153 153 SER j 91 LEU j 112 1 22
HELIX 154 154 ARG j 113 GLN j 120 1 8
HELIX 155 155 PRO j 122 SER j 135 1 14
HELIX 156 156 ALA j 141 ASP j 151 1 11
HELIX 157 157 THR j 153 ILE j 158 1 6
HELIX 158 158 SER j 162 SER j 174 1 13
HELIX 159 159 GLU j 196 GLU j 209 1 14
HELIX 160 160 GLY j 240 LYS j 257 1 18
HELIX 161 161 GLY k 112 SER k 121 1 10
HELIX 162 162 ASP k 130 ASN k 135 1 6
HELIX 163 163 MET k 201 ALA k 209 1 9
HELIX 164 164 GLN k 226 MET k 239 1 14
HELIX 165 165 GLU k 257 ILE k 270 1 14
HELIX 166 166 ASN k 290 THR k 301 1 12
HELIX 167 167 TYR l 131 ILE l 141 1 11
HELIX 168 168 ASN l 176 HIS l 185 1 10
HELIX 169 169 SER l 187 LEU l 199 1 13
HELIX 170 170 LYS l 220 VAL l 234 1 15
HELIX 171 171 ASP m 50 PHE m 62 1 13
HELIX 172 172 ARG m 85 GLN m 95 1 11
HELIX 173 173 ARG o 7 GLY o 22 1 16
HELIX 174 174 LYS o 24 THR o 36 1 13
HELIX 175 175 VAL o 48 LYS o 63 1 16
HELIX 176 176 LYS o 64 GLN o 80 1 17
HELIX 177 177 SER o 82 ASP o 120 1 39
HELIX 178 178 ILE o 151 ARG o 170 1 20
HELIX 179 179 GLU o 176 TYR o 193 1 18
HELIX 180 180 LYS o 196 GLN o 217 1 22
HELIX 181 181 ALA o 230 LEU o 250 1 21
HELIX 182 182 TRP o 253 SER o 270 1 18
HELIX 183 183 SER o 277 PHE o 290 1 14
HELIX 184 184 ASP o 295 ASN o 313 1 19
HELIX 185 185 THR o 317 THR o 335 1 19
HELIX 186 186 ASP o 346 MET o 351 5 6
HELIX 187 187 THR o 362 GLU o 372 1 11
HELIX 188 188 ASP o 373 GLY o 378 1 6
HELIX 189 189 ASP o 381 VAL o 393 1 13
HELIX 190 190 ASP o 396 SER o 412 1 17
HELIX 191 191 ILE o 421 PHE o 440 1 20
HELIX 192 192 GLN o 445 THR o 453 1 9
HELIX 193 193 SER o 461 GLU o 475 1 15
HELIX 194 194 UNK o 754 UNK o 769 1 16
HELIX 195 195 UNK o 773 UNK o 785 1 13
HELIX 196 196 UNK o 789 UNK o 802 1 14
HELIX 197 197 UNK o 807 UNK o 818 1 12
HELIX 198 198 UNK o 829 UNK o 834 1 6
HELIX 199 199 UNK o 838 UNK o 846 1 9
HELIX 200 200 UNK o 851 UNK o 866 1 16
HELIX 201 201 UNK p 21 UNK p 32 1 12
HELIX 202 202 UNK p 117 UNK p 135 1 19
HELIX 203 203 UNK p 140 UNK p 148 1 9
HELIX 204 204 UNK p 151 UNK p 158 1 8
HELIX 205 205 UNK p 171 UNK p 185 1 15
HELIX 206 206 TYR p 195 SER p 206 1 12
HELIX 207 207 UNK p 212 UNK p 218 1 7
HELIX 208 208 GLU p 252 LYS p 267 1 16
HELIX 209 209 ASN p 271 ALA p 286 1 16
HELIX 210 210 LYS p 288 SER p 307 1 20
HELIX 211 211 PRO p 314 ILE p 336 1 23
HELIX 212 212 ASP p 337 VAL p 341 5 5
HELIX 213 213 SER p 368 ILE p 387 1 20
HELIX 214 214 SER p 391 LEU p 419 1 29
HELIX 215 215 ASP p 421 HIS p 439 1 19
HELIX 216 216 SER p 444 ILE p 459 1 16
HELIX 217 217 ASP p 477 SER p 491 1 15
HELIX 218 218 ASN p 495 LYS p 514 1 20
HELIX 219 219 ASP p 515 GLN p 527 1 13
HELIX 220 220 SER p 537 CYS p 558 1 22
HELIX 221 221 LEU p 559 LEU p 567 1 9
HELIX 222 222 LEU p 585 LEU p 590 1 6
HELIX 223 223 ASN p 613 GLY p 639 1 27
HELIX 224 224 SER p 651 LEU p 662 1 12
HELIX 225 225 THR p 670 GLY p 685 1 16
HELIX 226 226 TRP p 687 ILE p 697 1 11
HELIX 227 227 LYS p 698 ALA p 701 5 4
HELIX 228 228 MET p 706 PHE p 729 1 24
HELIX 229 229 SER p 737 PHE p 745 1 9
HELIX 230 230 PRO p 748 GLU p 764 1 17
HELIX 231 231 ASP p 782 LEU p 794 1 13
HELIX 232 232 GLU q 323 PHE q 329 1 7
HELIX 233 233 GLU q 334 GLU q 341 1 8
HELIX 234 234 HIS r 705 SER r 727 1 23
HELIX 235 235 HIS s 46 ASN s 54 1 9
HELIX 236 236 TYR s 58 LYS s 62 5 5
HELIX 237 237 ASN s 86 GLN s 96 1 11
SHEET 1 A 2 VAL A 37 ALA A 40 0
SHEET 2 A 2 ASN A 46 ILE A 48 -1 O VAL A 47 N TYR A 38
SHEET 1 B 4 THR A 96 ALA A 99 0
SHEET 2 B 4 VAL A 73 SER A 77 1 N VAL A 73 O THR A 96
SHEET 3 B 4 LEU A 120 VAL A 123 1 O ILE A 122 N ILE A 76
SHEET 4 B 4 VAL A 143 ALA A 145 1 O ILE A 144 N VAL A 123
SHEET 1 C 5 ASN B 42 ASN B 49 0
SHEET 2 C 5 LYS B 27 LYS B 33 -1 N GLU B 28 O VAL B 48
SHEET 3 C 5 ASN B 95 PHE B 105 1 O LEU B 96 N LYS B 33
SHEET 4 C 5 ARG B 82 VAL B 91 -1 N LYS B 83 O ASP B 104
SHEET 5 C 5 VAL B 65 CYS B 69 -1 N VAL B 68 O VAL B 84
SHEET 1 D 3 LEU B 120 VAL B 127 0
SHEET 2 D 3 VAL B 134 PHE B 142 -1 O ILE B 137 N VAL B 125
SHEET 3 D 3 GLN B 208 HIS B 211 -1 O HIS B 211 N ILE B 140
SHEET 1 E 3 LEU B 120 VAL B 127 0
SHEET 2 E 3 VAL B 134 PHE B 142 -1 O ILE B 137 N VAL B 125
SHEET 3 E 3 VAL B 215 LYS B 219 -1 O LYS B 216 N ARG B 136
SHEET 1 F 4 GLU C 84 GLN C 94 0
SHEET 2 F 4 GLN C 99 GLY C 110 -1 O VAL C 106 N MET C 86
SHEET 3 F 4 HIS C 115 ALA C 123 -1 O ALA C 123 N PHE C 103
SHEET 4 F 4 ILE C 142 PRO C 143 -1 O ILE C 142 N VAL C 116
SHEET 1 G 2 ARG C 146 GLY C 147 0
SHEET 2 G 2 SER C 158 LEU C 159 -1 O SER C 158 N GLY C 147
SHEET 1 H 4 THR C 163 LYS C 166 0
SHEET 2 H 4 SER C 171 PRO C 176 -1 O LEU C 174 N THR C 163
SHEET 3 H 4 VAL C 201 THR C 203 -1 O TYR C 202 N ILE C 175
SHEET 4 H 4 ILE C 183 VAL C 184 1 N VAL C 184 O VAL C 201
SHEET 1 I 3 TYR D 34 VAL D 41 0
SHEET 2 I 3 THR D 46 ALA D 52 -1 O GLU D 47 N ARG D 40
SHEET 3 I 3 ILE D 84 ARG D 90 1 O ALA D 85 N THR D 46
SHEET 1 J 4 ALA D 147 ASP D 154 0
SHEET 2 J 4 CYS D 134 LYS D 141 -1 N GLY D 140 O LYS D 148
SHEET 3 J 4 VAL D 181 MET D 189 -1 O GLY D 183 N SER D 139
SHEET 4 J 4 ILE D 168 LEU D 176 -1 N VAL D 175 O LEU D 182
SHEET 1 K 4 VAL E 70 VAL E 72 0
SHEET 2 K 4 VAL E 89 LEU E 92 -1 O THR E 91 N LYS E 71
SHEET 3 K 4 ASN E 98 ARG E 100 -1 O PHE E 99 N ILE E 90
SHEET 4 K 4 ARG E 113 ILE E 114 -1 O ILE E 114 N ASN E 98
SHEET 1 L 2 VAL E 102 TYR E 103 0
SHEET 2 L 2 PHE E 109 ALA E 110 -1 O ALA E 110 N VAL E 102
SHEET 1 M 5 THR E 146 ARG E 148 0
SHEET 2 M 5 PRO E 137 THR E 141 -1 N VAL E 139 O ILE E 147
SHEET 3 M 5 LYS E 122 LEU E 131 -1 N GLN E 130 O TYR E 138
SHEET 4 M 5 THR E 159 VAL E 162 -1 O VAL E 162 N LYS E 122
SHEET 5 M 5 ILE E 169 ILE E 173 -1 O ILE E 173 N THR E 159
SHEET 1 N 4 VAL E 192 GLY E 193 0
SHEET 2 N 4 LEU E 180 VAL E 183 -1 N VAL E 181 O GLY E 193
SHEET 3 N 4 VAL E 225 GLU E 230 -1 O ILE E 228 N LEU E 180
SHEET 4 N 4 ARG E 233 PRO E 234 -1 O ARG E 233 N GLU E 230
SHEET 1 O 3 HIS E 197 ARG E 198 0
SHEET 2 O 3 LEU E 207 ILE E 210 -1 O HIS E 209 N HIS E 197
SHEET 3 O 3 PHE E 218 ARG E 221 -1 O PHE E 218 N ILE E 210
SHEET 1 P 6 GLU F 146 THR F 149 0
SHEET 2 P 6 GLN F 160 VAL F 164 -1 O VAL F 162 N ASP F 147
SHEET 3 P 6 THR c 39 LYS c 45 1 O LYS c 45 N ASP F 163
SHEET 4 P 6 VAL c 25 PHE c 32 -1 N VAL c 28 O ARG c 42
SHEET 5 P 6 THR c 8 THR c 19 -1 N THR c 19 O VAL c 25
SHEET 6 P 6 ILE c 53 LEU c 56 -1 O LEU c 54 N ALA c 10
SHEET 1 Q 5 THR G 12 GLU G 17 0
SHEET 2 Q 5 LYS G 2 TYR G 7 -1 N TYR G 7 O THR G 12
SHEET 3 Q 5 LEU G 106 LYS G 115 1 O LEU G 109 N ASN G 4
SHEET 4 Q 5 VAL G 49 ASP G 57 -1 N ALA G 53 O ALA G 110
SHEET 5 Q 5 GLN G 34 ASP G 37 -1 N VAL G 36 O PHE G 50
SHEET 1 R 2 LYS G 30 ARG G 31 0
SHEET 2 R 2 ILE G 101 VAL G 102 -1 O VAL G 102 N LYS G 30
SHEET 1 S 2 VAL G 73 LEU G 77 0
SHEET 2 S 2 LYS G 93 VAL G 97 -1 O VAL G 97 N VAL G 73
SHEET 1 T 2 ARG G 160 THR G 163 0
SHEET 2 T 2 SER G 168 LYS G 171 -1 O TYR G 169 N VAL G 162
SHEET 1 U 3 ILE H 46 GLU H 50 0
SHEET 2 U 3 LYS H 56 VAL H 62 -1 O ALA H 57 N ILE H 49
SHEET 3 U 3 VAL H 90 ALA H 94 1 O ILE H 91 N VAL H 60
SHEET 1 V 6 GLN H 180 GLU H 184 0
SHEET 2 V 6 LYS H 148 LEU H 154 1 N GLN H 150 O GLN H 180
SHEET 3 V 6 ILE H 135 TYR H 142 -1 N GLY H 137 O LEU H 153
SHEET 4 V 6 GLU W 51 ILE W 53 -1 O TYR W 52 N VAL H 140
SHEET 5 V 6 LYS W 60 GLN W 64 -1 O VAL W 62 N GLU W 51
SHEET 6 V 6 GLN W 24 ILE W 27 -1 N ILE W 27 O ILE W 61
SHEET 1 W 2 ILE I 3 SER I 4 0
SHEET 2 W 2 LEU I 29 GLY I 30 -1 O GLY I 30 N ILE I 3
SHEET 1 X 2 THR I 36 LYS I 37 0
SHEET 2 X 2 THR I 95 LEU I 96 -1 O LEU I 96 N THR I 36
SHEET 1 Y 2 HIS I 44 THR I 48 0
SHEET 2 Y 2 GLY I 51 ARG I 56 -1 O ARG I 56 N HIS I 44
SHEET 1 Z 6 THR I 62 TRP I 67 0
SHEET 2 Z 6 VAL I 72 TYR I 83 -1 O THR I 76 N GLY I 63
SHEET 3 Z 6 ILE I 101 ILE I 104 -1 O ILE I 101 N VAL I 82
SHEET 4 Z 6 LEU I 166 ILE I 170 -1 O ALA I 168 N VAL I 102
SHEET 5 Z 6 ASP I 181 ILE I 184 -1 O TYR I 183 N ALA I 169
SHEET 6 Z 6 THR I 62 TRP I 67 1 N SER I 66 O ILE I 184
SHEET 1 AA 3 VAL K 20 LEU K 21 0
SHEET 2 AA 3 TYR K 65 LEU K 68 -1 O TYR K 66 N LEU K 21
SHEET 3 AA 3 VAL K 55 GLN K 58 -1 N GLN K 58 O TYR K 65
SHEET 1 AB 6 ILE L 66 SER L 77 0
SHEET 2 AB 6 THR L 83 ARG L 87 -1 O VAL L 85 N VAL L 76
SHEET 3 AB 6 ASN L 106 HIS L 110 -1 O ALA L 109 N ILE L 84
SHEET 4 AB 6 PHE L 137 VAL L 142 1 O VAL L 139 N HIS L 110
SHEET 5 AB 6 ILE L 122 CYS L 128 -1 N THR L 124 O LYS L 141
SHEET 6 AB 6 ILE L 66 SER L 77 -1 N LEU L 71 O VAL L 125
SHEET 1 AC 2 TYR L 90 VAL L 94 0
SHEET 2 AC 2 ARG L 99 ARG L 103 -1 O ARG L 103 N TYR L 90
SHEET 1 AD 2 LEU M 52 LEU M 55 0
SHEET 2 AD 2 VAL M 111 VAL M 114 -1 O VAL M 112 N VAL M 54
SHEET 1 AE 4 THR O 26 VAL O 28 0
SHEET 2 AE 4 ILE O 19 ALA O 21 -1 N PHE O 20 O PHE O 27
SHEET 3 AE 4 ALA O 78 ARG O 84 1 O ARG O 84 N ALA O 21
SHEET 4 AE 4 ARG O 111 ASP O 117 1 O GLU O 116 N ILE O 83
SHEET 1 AF 3 VAL P 76 THR P 78 0
SHEET 2 AF 3 VAL P 94 TYR P 97 1 O GLY P 95 N THR P 78
SHEET 3 AF 3 PHE P 102 VAL P 105 -1 O ASN P 103 N VAL P 96
SHEET 1 AG 3 VAL Q 7 THR Q 9 0
SHEET 2 AG 3 ALA Q 16 ALA Q 24 -1 O VAL Q 22 N VAL Q 7
SHEET 3 AG 3 LYS Q 12 LYS Q 13 -1 N LYS Q 13 O ALA Q 16
SHEET 1 AH 5 VAL Q 7 THR Q 9 0
SHEET 2 AH 5 ALA Q 16 ALA Q 24 -1 O VAL Q 22 N VAL Q 7
SHEET 3 AH 5 ILE Q 63 THR Q 70 -1 O THR Q 70 N THR Q 17
SHEET 4 AH 5 LEU Q 28 VAL Q 31 1 N LYS Q 30 O ILE Q 65
SHEET 5 AH 5 SER Q 34 PRO Q 35 -1 N SER Q 34 O VAL Q 31
SHEET 1 AI 2 ASN R 101 VAL R 102 0
SHEET 2 AI 2 SER R 120 VAL R 121 1 O SER R 120 N VAL R 102
SHEET 1 AJ 2 GLY T 81 ALA T 83 0
SHEET 2 AJ 2 HIS T 93 ASP T 95 -1 O VAL T 94 N GLY T 82
SHEET 1 AK 2 VAL T 114 ILE T 116 0
SHEET 2 AK 2 ARG T 122 ILE T 124 -1 O ARG T 123 N GLU T 115
SHEET 1 AL 4 VAL U 51 VAL U 56 0
SHEET 2 AL 4 TYR U 90 GLU U 94 -1 O GLU U 94 N VAL U 51
SHEET 3 AL 4 ILE U 22 THR U 27 -1 N ILE U 22 O LEU U 93
SHEET 4 AL 4 ASP U 113 VAL U 116 -1 O GLU U 115 N ASN U 25
SHEET 1 AM 2 LYS U 61 ARG U 68 0
SHEET 2 AM 2 TRP U 79 ILE U 86 -1 O ASP U 80 N THR U 67
SHEET 1 AN 2 VAL V 32 ASP V 40 0
SHEET 2 AN 2 GLY V 43 LEU V 55 -1 O LEU V 55 N VAL V 32
SHEET 1 AO 3 GLY W 109 ASP W 112 0
SHEET 2 AO 3 TYR W 101 THR W 106 -1 N LEU W 104 O MET W 111
SHEET 3 AO 3 LYS W 124 VAL W 129 -1 O VAL W 129 N TYR W 101
SHEET 1 AP 7 VAL X 130 SER X 131 0
SHEET 2 AP 7 LYS X 123 VAL X 127 -1 N VAL X 127 O VAL X 130
SHEET 3 AP 7 GLU X 101 ALA X 105 -1 N LEU X 103 O VAL X 125
SHEET 4 AP 7 ALA X 49 ILE X 57 -1 N ALA X 49 O LEU X 104
SHEET 5 AP 7 CYS X 71 LEU X 76 -1 O ARG X 73 N GLU X 55
SHEET 6 AP 7 LYS X 82 PHE X 86 -1 O VAL X 83 N VAL X 74
SHEET 7 AP 7 LYS X 123 VAL X 127 1 O VAL X 124 N PHE X 86
SHEET 1 AQ 4 THR Y 6 ASN Y 15 0
SHEET 2 AQ 4 ARG Y 20 LEU Y 28 -1 O ARG Y 20 N ASN Y 15
SHEET 3 AQ 4 LYS Y 68 TYR Y 76 -1 O GLY Y 73 N PHE Y 23
SHEET 4 AQ 4 VAL Y 55 THR Y 62 -1 N ARG Y 61 O THR Y 70
SHEET 1 AR 2 ILE Z 89 PRO Z 91 0
SHEET 2 AR 2 TYR Z 101 ARG Z 103 -1 O THR Z 102 N LYS Z 90
SHEET 1 AS 2 PRO a 20 ARG a 22 0
SHEET 2 AS 2 SER a 29 PRO a 31 -1 O VAL a 30 N VAL a 21
SHEET 1 AT 2 LYS a 37 ASN a 43 0
SHEET 2 AT 2 LYS a 66 HIS a 72 -1 O LEU a 71 N ARG a 38
SHEET 1 AU 3 ILE b 43 PHE b 47 0
SHEET 2 AU 3 PHE b 32 LYS b 36 -1 N VAL b 35 O THR b 44
SHEET 3 AU 3 SER b 78 ARG b 81 -1 O ARG b 80 N ASP b 34
SHEET 1 AV 2 CYS b 64 THR b 65 0
SHEET 2 AV 2 LYS b 72 LEU b 73 -1 O LYS b 72 N THR b 65
SHEET 1 AW 2 VAL f 108 ASP f 109 0
SHEET 2 AW 2 LYS f 113 VAL f 114 -1 O LYS f 113 N ASP f 109
SHEET 1 AX 3 ALA f 131 ASN f 132 0
SHEET 2 AX 3 PHE f 137 TYR f 138 -1 O TYR f 138 N ALA f 131
SHEET 3 AX 3 ALA f 147 THR f 148 -1 O THR f 148 N PHE f 137
SHEET 1 AY 4 ILE g 6 LEU g 14 0
SHEET 2 AY 4 ILE g 317 THR g 324 -1 O ILE g 317 N LEU g 14
SHEET 3 AY 4 THR g 307 TYR g 312 -1 N ALA g 310 O ARG g 318
SHEET 4 AY 4 ALA g 296 ALA g 300 -1 N VAL g 297 O GLY g 311
SHEET 1 AZ 4 SER g 23 LEU g 24 0
SHEET 2 AZ 4 LEU g 33 GLY g 37 -1 O GLY g 37 N SER g 23
SHEET 3 AZ 4 THR g 42 LEU g 48 -1 O ILE g 44 N SER g 36
SHEET 4 AZ 4 GLY g 56 LYS g 63 -1 O TYR g 62 N LEU g 43
SHEET 1 BA 4 VAL g 69 VAL g 74 0
SHEET 2 BA 4 TYR g 80 SER g 85 -1 O VAL g 82 N VAL g 73
SHEET 3 BA 4 THR g 89 ASN g 94 -1 O TRP g 93 N ALA g 81
SHEET 4 BA 4 ASN g 99 VAL g 105 -1 O ALA g 102 N LEU g 92
SHEET 1 BB 4 VAL g 111 ALA g 115 0
SHEET 2 BB 4 ILE g 123 SER g 127 -1 O ALA g 126 N LEU g 112
SHEET 3 BB 4 ILE g 132 TRP g 135 -1 O ARG g 133 N SER g 125
SHEET 4 BB 4 CYS g 141 LEU g 145 -1 O TYR g 143 N VAL g 134
SHEET 1 BC 4 VAL g 152 VAL g 157 0
SHEET 2 BC 4 ILE g 172 GLY g 178 -1 O VAL g 175 N ARG g 156
SHEET 3 BC 4 ILE g 182 LEU g 188 -1 O ARG g 184 N SER g 176
SHEET 4 BC 4 ASP g 198 ILE g 200 -1 O PHE g 199 N VAL g 183
SHEET 1 BD 4 VAL g 208 PRO g 211 0
SHEET 2 BD 4 LEU g 217 ALA g 221 -1 O ALA g 221 N VAL g 208
SHEET 3 BD 4 GLN g 226 ASN g 231 -1 O TRP g 230 N ALA g 218
SHEET 4 BD 4 SER g 236 ASP g 242 -1 O PHE g 241 N ILE g 227
SHEET 1 BE 4 VAL g 247 PHE g 252 0
SHEET 2 BE 4 TRP g 258 THR g 263 -1 O ALA g 262 N PHE g 248
SHEET 3 BE 4 ILE g 267 ASP g 271 -1 O LYS g 268 N ALA g 261
SHEET 4 BE 4 LEU g 277 LEU g 281 -1 O ILE g 278 N ILE g 269
SHEET 1 BF 6 GLN i 33 MET i 41 0
SHEET 2 BF 6 ARG i 46 CYS i 51 -1 O SER i 50 N GLN i 37
SHEET 3 BF 6 MET i 58 HIS i 60 -1 O ALA i 59 N VAL i 47
SHEET 4 BF 6 GLN i 88 LYS i 94 1 O CYS i 89 N MET i 58
SHEET 5 BF 6 ILE i 76 LEU i 81 -1 N LEU i 78 O HIS i 93
SHEET 6 BF 6 GLN i 33 MET i 41 -1 N ALA i 36 O ILE i 77
SHEET 1 BG 6 ILE j 19 ASN j 23 0
SHEET 2 BG 6 GLY j 31 LEU j 36 -1 O LYS j 35 N ASN j 23
SHEET 3 BG 6 GLU j 43 LEU j 47 -1 O GLY j 44 N VAL j 34
SHEET 4 BG 6 ILE j 83 SER j 86 1 O LEU j 85 N MET j 45
SHEET 5 BG 6 ASN j 68 VAL j 76 -1 N VAL j 72 O SER j 86
SHEET 6 BG 6 ILE j 19 ASN j 23 -1 N VAL j 22 O ASP j 69
SHEET 1 BH 4 LYS j 219 LEU j 222 0
SHEET 2 BH 4 LEU j 227 GLN j 233 -1 O THR j 231 N LYS j 219
SHEET 3 BH 4 LYS j 183 VAL j 190 -1 N ALA j 186 O LEU j 230
SHEET 4 BH 4 CYS j 262 ASN j 263 -1 O ASN j 263 N GLU j 189
SHEET 1 BI 6 ASN k 144 LYS k 149 0
SHEET 2 BI 6 LYS k 184 ASP k 193 -1 O VAL k 189 N ALA k 145
SHEET 3 BI 6 ASN k 102 GLY k 107 1 N ILE k 103 O SER k 190
SHEET 4 BI 6 ALA k 213 ILE k 218 1 O LEU k 215 N ILE k 106
SHEET 5 BI 6 VAL k 244 GLN k 248 1 O LEU k 247 N ILE k 218
SHEET 6 BI 6 ILE k 280 PRO k 282 1 O VAL k 281 N GLN k 248
SHEET 1 BJ 8 ASN k 385 LEU k 387 0
SHEET 2 BJ 8 CYS k 370 ALA k 382 -1 N LEU k 380 O LEU k 387
SHEET 3 BJ 8 GLY k 394 THR k 400 -1 O GLY k 397 N PHE k 381
SHEET 4 BJ 8 GLY k 336 ASN k 344 -1 N GLY k 336 O THR k 400
SHEET 5 BJ 8 ARG k 314 ASP k 322 -1 N ILE k 316 O SER k 341
SHEET 6 BJ 8 GLN k 415 ALA k 419 -1 O VAL k 417 N LEU k 315
SHEET 7 BJ 8 GLU k 352 VAL k 360 -1 N GLU k 354 O GLY k 418
SHEET 8 BJ 8 CYS k 370 ALA k 382 -1 O ILE k 373 N ILE k 355
SHEET 1 BK 2 PHE k 347 LYS k 348 0
SHEET 2 BK 2 PHE k 389 ALA k 390 -1 O ALA k 390 N PHE k 347
SHEET 1 BL 7 ASN k 425 LEU k 441 0
SHEET 2 BL 7 MET k 482 THR k 493 -1 O LEU k 485 N ILE k 430
SHEET 3 BL 7 THR k 469 VAL k 478 -1 N ARG k 474 O GLN k 486
SHEET 4 BL 7 VAL k 461 ILE k 466 -1 N LEU k 462 O ALA k 473
SHEET 5 BL 7 LYS k 498 ARG k 504 -1 O ALA k 500 N ASN k 465
SHEET 6 BL 7 TRP k 509 ILE k 517 -1 O ARG k 510 N ARG k 503
SHEET 7 BL 7 ASN k 425 LEU k 441 -1 N PHE k 435 O TRP k 514
SHEET 1 BM 3 ILE l 173 PHE l 174 0
SHEET 2 BM 3 ARG l 210 VAL l 212 -1 O LEU l 211 N PHE l 174
SHEET 3 BM 3 SER l 204 ASP l 206 -1 N ASP l 206 O ARG l 210
SHEET 1 BN 5 ILE m 68 LYS m 70 0
SHEET 2 BN 5 GLU m 76 GLN m 81 -1 O ILE m 77 N VAL m 69
SHEET 3 BN 5 LEU m 39 GLN m 43 -1 N THR m 40 O LEU m 80
SHEET 4 BN 5 HIS m 27 GLN m 31 -1 N GLN m 31 O LEU m 39
SHEET 5 BN 5 ILE m 105 HIS m 106 1 O HIS m 106 N ILE m 28
SHEET 1 BO 3 THR o 442 SER o 444 0
SHEET 2 BO 3 LYS o 488 PHE o 491 -1 O VAL o 489 N VAL o 443
SHEET 3 BO 3 ILE o 480 ILE o 482 -1 N THR o 481 O THR o 490
SHEET 1 BP 2 LYS p 768 LEU p 769 0
SHEET 2 BP 2 PHE p 776 VAL p 777 -1 O VAL p 777 N LYS p 768
SHEET 1 BQ 5 THR q 298 ILE q 301 0
SHEET 2 BQ 5 SER q 307 GLY q 311 -1 O GLY q 311 N THR q 298
SHEET 3 BQ 5 ILE q 317 HIS q 321 -1 O ARG q 318 N SER q 310
SHEET 4 BQ 5 LYS q 2 LEU q 6 -1 N ILE q 4 O LEU q 319
SHEET 5 BQ 5 THR s 72 GLU s 78 -1 O ALA s 73 N LYS q 5
SHEET 1 BR 4 LEU q 13 TYR q 18 0
SHEET 2 BR 4 LEU q 24 SER q 29 -1 O CYS q 28 N THR q 14
SHEET 3 BR 4 ALA q 34 TYR q 38 -1 O SER q 35 N SER q 27
SHEET 4 BR 4 ARG q 44 LEU q 48 -1 O GLY q 46 N VAL q 36
SHEET 1 BS 4 ILE q 55 VAL q 60 0
SHEET 2 BS 4 TYR q 66 SER q 71 -1 O VAL q 68 N ASP q 59
SHEET 3 BS 4 SER q 75 ASP q 80 -1 O TRP q 79 N CYS q 67
SHEET 4 BS 4 CYS q 86 LYS q 91 -1 O TRP q 90 N ILE q 76
SHEET 1 BT 4 VAL q 96 PHE q 101 0
SHEET 2 BT 4 PHE q 108 LEU q 112 -1 O ILE q 111 N ARG q 98
SHEET 3 BT 4 SER q 121 ILE q 124 -1 O ASN q 123 N ALA q 110
SHEET 4 BT 4 HIS q 145 ILE q 148 -1 O ILE q 147 N ILE q 122
SHEET 1 BU 2 ILE q 127 ARG q 129 0
SHEET 2 BU 2 LEU q 136 VAL q 139 -1 O THR q 137 N GLU q 128
SHEET 1 BV 4 ALA q 156 TRP q 161 0
SHEET 2 BV 4 TYR q 167 HIS q 172 -1 O GLY q 171 N VAL q 158
SHEET 3 BV 4 LYS q 176 ASP q 181 -1 O SER q 178 N ALA q 170
SHEET 4 BV 4 GLU q 187 ASP q 193 -1 O GLU q 187 N ASP q 181
SHEET 1 BW 4 ILE q 199 PHE q 204 0
SHEET 2 BW 4 TYR q 210 SER q 215 -1 O ILE q 212 N GLN q 203
SHEET 3 BW 4 SER q 220 ASP q 224 -1 O VAL q 223 N PHE q 211
SHEET 4 BW 4 VAL q 230 TYR q 234 -1 O TYR q 234 N SER q 220
SHEET 1 BX 4 LEU q 240 ILE q 245 0
SHEET 2 BX 4 PHE q 251 GLY q 256 -1 O GLY q 255 N ASN q 241
SHEET 3 BX 4 ALA q 275 HIS q 279 -1 O ARG q 276 N LEU q 254
SHEET 4 BX 4 GLU q 285 ARG q 288 -1 O ILE q 286 N PHE q 277
LINK OP2 G 2 16 MG MG 21815 1555 1555 2.38
LINK OP1 G 2 16 MG MG 21815 1555 1555 2.83
LINK O3' U 2 27 MG MG 21817 1555 1555 2.82
LINK OP2 A 2 28 MG MG 21817 1555 1555 1.92
LINK OP1 A 2 28 MG MG 21817 1555 1555 2.47
LINK OP2 A 2 47 MG MG 21821 1555 1555 1.92
LINK O5' A 2 47 MG MG 21821 1555 1555 2.42
LINK OP1 A 2 47 MG MG 21821 1555 1555 2.81
LINK OP2 C 2 49 MG MG 21807 1555 1555 1.92
LINK OP2 U 2 64 MG MG 21835 1555 1555 2.03
LINK OP1 U 2 64 MG MG 21835 1555 1555 2.87
LINK OP2 G 2 95 MG MG 21832 1555 1555 2.44
LINK O3' C 2 99 MG MG 21828 1555 1555 2.39
LINK OP1 A 2 100 MG MG 21804 1555 1555 2.27
LINK OP2 A 2 100 MG MG 21828 1555 1555 1.97
LINK OP2 C 2 360 MG MG 21828 1555 1555 1.76
LINK OP1 C 2 360 MG MG 21828 1555 1555 2.14
LINK O5' C 2 360 MG MG 21828 1555 1555 2.21
LINK OP2 A 2 377 MG MG 21816 1555 1555 1.93
LINK OP2 U 2 378 MG MG 21816 1555 1555 2.01
LINK O3' A 2 399 MG MG 21814 1555 1555 2.46
LINK OP2 A 2 400 MG MG 21814 1555 1555 1.93
LINK OP1 A 2 400 MG MG 21814 1555 1555 2.57
LINK O3' C 2 401 MG MG 21802 1555 1555 2.56
LINK OP1 G 2 402 MG MG 21802 1555 1555 1.93
LINK OP2 G 2 460 MG MG 21837 1555 1555 1.89
LINK OP1 G 2 460 MG MG 21837 1555 1555 2.07
LINK O5' G 2 460 MG MG 21837 1555 1555 2.44
LINK OP2 G 2 466 MG MG 21838 1555 1555 2.26
LINK OP1 C 2 529 MG MG 21853 1555 1555 2.70
LINK OP2 C 2 530 MG MG 21853 1555 1555 2.93
LINK OP2 G 2 548 MG MG 21842 1555 1555 2.98
LINK OP2 A 2 554 MG MG 21803 1555 1555 1.96
LINK OP2 A 2 555 MG MG 21803 1555 1555 2.54
LINK O6 G 2 561 MG MG 21824 1555 1555 2.67
LINK OP2 A 2 604 MG MG 21818 1555 1555 1.92
LINK OP1 A 2 604 MG MG 21818 1555 1555 1.94
LINK OP2 U 2 607 MG MG 21815 1555 1555 2.11
LINK OP2 A 2 618 MG MG 21823 1555 1555 2.92
LINK OP1 A 2 618 MG MG 21825 1555 1555 1.92
LINK OP2 A 2 619 MG MG 21823 1555 1555 1.97
LINK OP2 A 2 620 MG MG 21823 1555 1555 1.88
LINK OP2 G 2 623 MG MG 21805 1555 1555 2.54
LINK OP1 C 2 624 MG MG 21839 1555 1555 2.18
LINK OP2 A 2 760 MG MG 21850 1555 1555 2.71
LINK O6 G 2 761 MG MG 21850 1555 1555 2.41
LINK OP2 A 2 928 MG MG 21811 1555 1555 2.38
LINK OP2 A 2 978 MG MG 21848 1555 1555 2.02
LINK O6 G 2 984 MG MG 21840 1555 1555 2.67
LINK O6 G 2 985 MG MG 21840 1555 1555 2.68
LINK OP1 U 2 988 MG MG 21857 1555 1555 2.82
LINK OP2 U 21003 MG MG 21819 1555 1555 2.77
LINK OP1 U 21003 MG MG 21819 1555 1555 2.77
LINK OP2 A 21004 MG MG 21808 1555 1555 2.91
LINK OP1 U 21008 MG MG 21863 1555 1555 1.91
LINK O5' U 21008 MG MG 21863 1555 1555 2.98
LINK OP2 A 21024 MG MG 21805 1555 1555 2.50
LINK OP1 A 21025 MG MG 21827 1555 1555 2.91
LINK OP2 U 21054 MG MG 21865 1555 1555 2.87
LINK OP1 C 21196 MG MG 21874 1555 1555 1.91
LINK OP2 C 21196 MG MG 21874 1555 1555 2.84
LINK OP2 G 21199 MG MG 21872 1555 1555 2.98
LINK OP1 G 21200 MG MG 21872 1555 1555 1.94
LINK OP1 A 21201 MG MG 21880 1555 1555 2.30
LINK OP2 A 21202 MG MG 21880 1555 1555 1.92
LINK OP1 U 21268 MG MG 21875 1555 1555 1.96
LINK OP2 C 21273 MG MG 21876 1555 1555 2.55
LINK OP1 C 21273 MG MG 21879 1555 1555 1.89
LINK OP2 C 21273 MG MG 21879 1555 1555 2.51
LINK OP1 U 21282 MG MG 21868 1555 1555 2.41
LINK O6 G 21293 MG MG 21854 1555 1555 2.66
LINK OP2 U 21302 MG MG 21847 1555 1555 2.72
LINK OP2 G 21327 MG MG 21826 1555 1555 1.86
LINK O5' G 21327 MG MG 21826 1555 1555 2.27
LINK OP2 G 21329 MG MG 21809 1555 1555 1.92
LINK OP1 G 21426 MG MG 21876 1555 1555 1.82
LINK OP2 G 21426 MG MG 21876 1555 1555 1.83
LINK O5' G 21426 MG MG 21876 1555 1555 2.87
LINK OP1 G 21426 MG MG 21879 1555 1555 1.93
LINK OP2 G 21426 MG MG 21879 1555 1555 2.99
LINK OP2 G 21427 MG MG 21876 1555 1555 1.92
LINK OP2 G 21427 MG MG 21879 1555 1555 1.86
LINK O2' C 21429 MG MG 21873 1555 1555 2.66
LINK OP1 C 21455 MG MG 21871 1555 1555 2.31
LINK OP2 G 21482 MG MG 21878 1555 1555 2.74
LINK OP1 U 21520 MG MG 21878 1555 1555 2.67
LINK OP2 G 21539 MG MG 21859 1555 1555 2.94
LINK O6 G 21539 MG MG 21877 1555 1555 2.62
LINK OP2 G 21540 MG MG 21859 1555 1555 2.65
LINK OP2 A 21760 MG MG 21822 1555 1555 1.84
LINK OP1 A 21761 MG MG 21812 1555 1555 1.74
LINK OP2 A 21761 MG MG 21822 1555 1555 1.92
LINK O2' G 21765 MG MG 21822 1555 1555 2.94
LINK OP2 G 21766 MG MG 21822 1555 1555 1.83
LINK OP2 U 21768 MG MG 21831 1555 1555 2.12
LINK OP1 U 21769 MG MG 21812 1555 1555 1.93
LINK O3' G 21790 MG MG 21834 1555 1555 2.92
LINK OP2 G 21791 MG MG 21834 1555 1555 1.93
LINK O5' G 21791 MG MG 21834 1555 1555 2.23
LINK SG CYS a 23 ZN ZN a 500 1555 1555 1.92
LINK SG CYS a 26 ZN ZN a 500 1555 1555 2.90
LINK SG CYS a 77 ZN ZN a 500 1555 1555 2.74
LINK SG CYS b 59 ZN ZN b 101 1555 1555 2.19
LINK O CYS b 59 ZN ZN b 101 1555 1555 2.62
LINK SG CYS f 121 ZN ZN f 501 1555 1555 2.01
LINK SG CYS f 124 ZN ZN f 501 1555 1555 2.59
LINK SG CYS f 139 ZN ZN f 501 1555 1555 2.05
LINK OG1 THR k 137 MG MG k 602 1555 1555 2.44
LINK MG MG k 602 O1G GCP k 603 1555 1555 2.70
LINK SG CYS l 262 ZN ZN l 301 1555 1555 2.58
LINK OG SER l 264 ZN ZN l 301 1555 1555 2.63
SITE 1 AC1 1 G 2 361
SITE 1 AC2 2 C 2 401 G 2 402
SITE 1 AC3 2 A 2 554 A 2 555
SITE 1 AC4 3 U 2 44 U 2 45 A 2 100
SITE 1 AC5 2 G 2 623 A 21024
SITE 1 AC6 2 G 2 556 C 2 582
SITE 1 AC7 2 C 2 49 G 2 387
SITE 1 AC8 2 U 21003 A 21004
SITE 1 AC9 2 G 21329 C 21418
SITE 1 BC1 1 A 2 928
SITE 1 BC2 3 A 21761 G 21766 U 21769
SITE 1 BC3 3 A 2 399 A 2 400 LYS I 23
SITE 1 BC4 2 G 2 16 U 2 607
SITE 1 BC5 3 G 2 376 A 2 377 U 2 378
SITE 1 BC6 2 U 2 27 A 2 28
SITE 1 BC7 3 A 2 603 A 2 604 G 2 606
SITE 1 BC8 3 G 2 996 A 2 997 U 21003
SITE 1 BC9 2 U 2 44 A 2 47
SITE 1 CC1 4 A 21760 A 21761 G 21765 G 21766
SITE 1 CC2 3 A 2 618 A 2 619 A 2 620
SITE 1 CC3 2 G 2 560 G 2 561
SITE 1 CC4 2 A 2 618 G 21790
SITE 1 CC5 3 G 21327 A 21328 G 21329
SITE 1 CC6 1 A 21025
SITE 1 CC7 4 C 2 99 A 2 100 A 2 359 C 2 360
SITE 1 CC8 1 G 2 20
SITE 1 CC9 1 U 21768
SITE 1 DC1 2 U 2 94 G 2 95
SITE 1 DC2 2 G 21725 U 21726
SITE 1 DC3 3 U 21628 G 21790 G 21791
SITE 1 DC4 2 G 2 63 U 2 64
SITE 1 DC5 2 A 2 459 G 2 460
SITE 1 DC6 2 U 2 465 G 2 466
SITE 1 DC7 1 C 2 624
SITE 1 DC8 3 G 2 984 G 2 985 G 21013
SITE 1 DC9 2 U 21412 G 21416
SITE 1 EC1 1 G 2 548
SITE 1 EC2 1 A 2 104
SITE 1 EC3 1 G 2 403
SITE 1 EC4 1 U 21302
SITE 1 EC5 2 A 2 977 A 2 978
SITE 1 EC6 3 U 2 759 A 2 760 G 2 761
SITE 1 EC7 3 C 2 826 A 2 843 G 2 844
SITE 1 EC8 2 C 2 529 C 2 530
SITE 1 EC9 3 G 21293 U 21302 MG 21855
SITE 1 FC1 1 MG 21854
SITE 1 FC2 1 U 2 988
SITE 1 FC3 1 A 2 212
SITE 1 FC4 2 G 21539 G 21540
SITE 1 FC5 2 U 21008 LYS O 129
SITE 1 FC6 2 U 21053 U 21054
SITE 1 FC7 2 C 21158 U 21282
SITE 1 FC8 2 A 21467 ASN T 85
SITE 1 FC9 3 G 21443 THR f 86 PRO f 88
SITE 1 GC1 1 C 21455
SITE 1 GC2 2 G 21199 G 21200
SITE 1 GC3 2 C 21429 U 21435
SITE 1 GC4 2 A 21195 C 21196
SITE 1 GC5 2 G 21267 U 21268
SITE 1 GC6 5 C 21273 A 21425 G 21426 G 21427
SITE 2 GC6 5 MG 21879
SITE 1 GC7 4 G 21539 G 21540 C 21566 A 21567
SITE 1 GC8 2 G 21482 U 21520
SITE 1 GC9 5 C 21273 G 21426 G 21427 MG 21876
SITE 2 GC9 5 ASN i 17
SITE 1 HC1 3 A 21201 A 21202 C 21597
SITE 1 HC2 4 CYS a 23 CYS a 26 CYS a 74 CYS a 77
SITE 1 HC3 3 CYS b 56 CYS b 59 THR b 61
SITE 1 HC4 3 CYS f 121 CYS f 124 CYS f 139
SITE 1 HC5 7 A 1 76 PHE k 321 PHE k 381 ALA k 382
SITE 2 HC5 7 GLU k 383 LEU k 395 GLY k 397
SITE 1 HC6 3 SER k 114 THR k 137 GCP k 603
SITE 1 HC7 18 HIS k 108 HIS k 111 GLY k 112 LYS k 113
SITE 2 HC7 18 SER k 114 THR k 115 ILE k 136 THR k 137
SITE 3 HC7 18 CYS k 194 GLY k 196 ASN k 249 ASP k 252
SITE 4 HC7 18 ALA k 285 GLN k 286 MG k 602 THR l 238
SITE 5 HC7 18 SER l 264 THR l 265
SITE 1 HC8 5 CYS l 236 THR l 238 CYS l 259 CYS l 262
SITE 2 HC8 5 SER l 264
CRYST1 1.000 1.000 1.000 90.00 90.00 90.00 P 1 1
ORIGX1 1.000000 0.000000 0.000000 0.00000
ORIGX2 0.000000 1.000000 0.000000 0.00000
ORIGX3 0.000000 0.000000 1.000000 0.00000
SCALE1 1.000000 0.000000 0.000000 0.00000
SCALE2 0.000000 1.000000 0.000000 0.00000
SCALE3 0.000000 0.000000 1.000000 0.00000
(ATOM LINES ARE NOT SHOWN.)
END
