KEGG   REACTION: R08391Help
Entry
R08391                      Reaction                               

Definition
Retinoate + NADPH + H+ + Oxygen <=> all-trans-5,6-Epoxyretinoic acid + NADP+ + H2O
Equation
Comment
CYP2A6, CYP2B6, CYP3A4/5, CYP2S1, CYP26
Reaction class
RC00001  C00005_C00006
RC01624  C00777_C16680
Enzyme
1.14.13.-       1.14.14.1
Pathway
rn00830  Retinol metabolism
Orthology
K07411  cytochrome P450 family 2 subfamily A [EC:1.14.14.1]
K07412  cytochrome P450 family 2 subfamily B [EC:1.14.14.1]
K07420  cytochrome P450 family 2 subfamily S polypeptide 1 [EC:1.14.14.1]
K07424  cytochrome P450 family 3 subfamily A [EC:1.14.14.1]
K17683  cytochrome P450 family 2 subfamily A polypeptide 6 [EC:1.14.13.-]
K17689  cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.13.-]
K17690  cytochrome P450 family 3 subfamily A polypeptide 5 [EC:1.14.14.1]
K17709  cytochrome P450 family 2 subfamily B polypeptide 6 [EC:1.14.13.-]

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