KEGG   REACTION: R04171
Entry
R04171                      Reaction                               
Name
3-hydroxy-L-kynurenine:2-oxoglutarate aminotransferase
Definition
3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate
Equation
C03227 + C00026 <=> C05645 + C00025
Comment
the first step of two-step reaction (see R04171+R03954)
Reaction class
RC00006  C00025_C00026  C03227_C05645
Enzyme
2.6.1.7
Pathway
rn00380  Tryptophan metabolism
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7
     R04171  3-Hydroxy-L-kynurenine + 2-Oxoglutarate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + L-Glutamate
Orthology
K00816  kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64]
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
K14264  kynurenine aminotransferase [EC:2.6.1.7]
Other DBs
RHEA: 65891

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KEGG   REACTION: R03954
Entry
R03954                      Reaction                               
Definition
Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Equation
C02470 + C00001 <=> C05645
Comment
spontaneous
the second step of two-step reaction (see R04171+R03954 / R12693, R12694+R03954)
Reaction class
RC00930  C02470_C05645
Enzyme
2.6.1.7         2.6.1.63
Pathway
rn00380  Tryptophan metabolism
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7
     R03954  Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
    2.6.1.63
     R03954  Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Other DBs
RHEA: 65895

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KEGG   REACTION: R12693
Entry
R12693                      Reaction                               
Name
3-hydroxy-L-kynurenine:glyoxylate aminotransferase (cyclizing)
Definition
3-Hydroxy-L-kynurenine + Glyoxylate <=> Xanthurenic acid + Glycine + H2O
Equation
C03227 + C00048 <=> C02470 + C00037 + C00001
Comment
two-step reaction (see R12694+R03954)
Enzyme
2.6.1.63
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.63
     R12693  3-Hydroxy-L-kynurenine + Glyoxylate <=> Xanthurenic acid + Glycine + H2O

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KEGG   REACTION: R12694
Entry
R12694                      Reaction                               
Definition
3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine
Equation
C03227 + C00048 <=> C05645 + C00037
Comment
the first step of two-step reaction (see R12693, R12694+R03954)
Reaction class
RC00006  C03227_C05645
Enzyme
2.6.1.63
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.63
     R12694  3-Hydroxy-L-kynurenine + Glyoxylate <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate + Glycine

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KEGG   REACTION: R03954
Entry
R03954                      Reaction                               
Definition
Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Equation
C02470 + C00001 <=> C05645
Comment
spontaneous
the second step of two-step reaction (see R04171+R03954 / R12693, R12694+R03954)
Reaction class
RC00930  C02470_C05645
Enzyme
2.6.1.7         2.6.1.63
Pathway
rn00380  Tryptophan metabolism
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7
     R03954  Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
    2.6.1.63
     R03954  Xanthurenic acid + H2O <=> 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate
Other DBs
RHEA: 65895

  All links  
No link information was found.
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