KEGG   Homo sapiens (human): 5982
Entry
5982              CDS       T01001                                 
Symbol
RFC2, RFC40
Name
(RefSeq) replication factor C subunit 2 isoform 1
  KO
K10755  replication factor C subunit 2/4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03030  DNA replication
hsa03410  Base excision repair
hsa03420  Nucleotide excision repair
hsa03430  Mismatch repair
Network
nt06503  Mismatch repair
nt06504  Base excision repair
nt06506  Double-strand break repair
nt06509  DNA replication
  Element
N01432  Mismatch repair
N01436  Long patch BER
N01452  Homologous recombination
N01471  Origin unwinding and elongation
Disease
H01439  Williams-Beuren syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    5982 (RFC2)
   03410 Base excision repair
    5982 (RFC2)
   03420 Nucleotide excision repair
    5982 (RFC2)
   03430 Mismatch repair
    5982 (RFC2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5982 (RFC2)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5982 (RFC2)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5982 (RFC2)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   RFC (replication factor C)
    5982 (RFC2)
  DNA Replication Termination Factors
   ELG1-RFC complex
    5982 (RFC2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid cohesion proteins
   CTF18-RFC complex
    5982 (RFC2)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    RFC (replication factor C)
     5982 (RFC2)
  Check point factors
   HRAD17(Rad24)-RFC complex
    5982 (RFC2)
SSDB
Motif
Pfam: Rep_fac_C AAA DNA_pol3_delta2 AAA_22 AAA_lid_RFC1 nSTAND_NTPase5 AAA_14 RCF1-5-like_lid AAA_16 Mg_chelatase Viral_helicase1 Rad17 AAA_11 RuvB_N AAA_assoc_2 DNAX_ATPase_lid AAA_19 nSTAND3 AAA_24 AAA_5 AAA_18 MipZ AAA_28 AAA_25 AAA_23 ABC_tran AAA_30 NTPase_1 SLFN-g3_helicase RNA_helicase DUF815 FtsK_SpoIIIE
Other DBs
NCBI-GeneID: 5982
NCBI-ProteinID: NP_852136
OMIM: 600404
HGNC: 9970
Ensembl: ENSP00000055077.3
UniProt: P35250
Structure
Position
7:complement(74231502..74254399)
AA seq 354 aa
MEVEAVCGGAGEVEAQDSDPAPAFSKAPGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRL
EVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAMLELNASNDRGIDVVRNKI
KMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEP
IQSRCAVLRYTKLTDAQILTRLMNVIEKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTF
SGFGFINSENVFKVCDEPHPLLVKEMIQHCVNANIDEAYKILAHLWHLGYSPEDIIGNIF
RVCKTFQMAEYLKLEFIKEIGYTHMKIAEGVNSLLQMAGLLARLCQKTMAPVAS
NT seq 1065 nt   +upstreamnt  +downstreamnt
atggaggtggaggccgtctgtggtggcgcgggcgaggtggaggcccaggactctgaccct
gcccctgccttcagcaaggcccccggcagcgccggccactacgaactgccgtgggttgaa
aaatataggccagtaaagctgaatgaaattgtcgggaatgaagacaccgtgagcaggcta
gaggtctttgcaagggaaggaaatgtgcccaacatcatcattgcgggccctccaggaacc
ggcaagaccacaagcattctgtgcttggcccgggccctgctgggcccagcactcaaagat
gccatgttggaactcaatgcttcaaatgacaggggcattgacgttgtgaggaataaaatt
aaaatgtttgctcaacaaaaagtcactcttcccaaaggccgacataagatcatcattctg
gatgaagcagacagcatgaccgacggagcccagcaagccttgaggagaaccatggaaatc
tactctaaaaccactcgcttcgcccttgcttgtaatgcttcggataagatcatcgagccc
attcagtcccgctgtgcagtcctccggtacacaaagctgaccgacgcccagatcctcacc
aggctgatgaatgttatcgagaaggagagggtaccctacactgatgacggcctagaagcc
atcatcttcacggcccagggagacatgaggcaggcgctgaacaacctgcagtccaccttc
tcaggatttggcttcattaacagtgagaacgtgttcaaggtctgtgacgagccccaccca
ctgctggtaaaggagatgatccagcactgtgtgaatgccaacattgacgaagcctacaag
attcttgctcacttgtggcatctgggctactcaccagaagatatcattggcaacatcttt
cgagtgtgtaaaactttccaaatggcagaatacctgaaactggagtttatcaaggaaatt
ggatacactcacatgaaaatagcggaaggagtgaactctcttttgcagatggcaggcctc
ctggcaaggctgtgtcagaagacaatggccccggtggccagttag

  All links  
Disease (1)   
   OMIM (1)   
Gene (10)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (35)   
   RefSeq(nuc) (9)   
   GenBank (13)   
   EMBL (13)   
3D Structure (15)   
   PDB (15)   
Protein domain (32)   
   Pfam (32)   
All databases (104)   

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