| Scientific Name | SARS coronavirus MA15 [TAX:633137] |
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| Lineage | Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae; Betacoronavirus; Sarbecovirus; Severe acute respiratory syndrome-related coronavirus; recombinant SARSr-CoV |
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| Baltimore Group | IV: ssRNA(+) |
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| Genome Type | Non-segmented |
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| Genbank |
SARS coronavirus MA15 isolate P3pp6, complete genome.
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| DBLINKS |
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Known hosts (3)
| Scientific Name |
Chlorocebus aethiops [TAX:9534]
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| Lineage | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Cercopithecinae; Chlorocebus |
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| Evidence |
Literature
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| Reference |
PMID: 17222058
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| Authors |
Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K
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| Title |
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
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| Journal |
PLoS Pathog. 2007 Jan;3(1):e5. |
| Comment |
Culture cell line: Vero E6 (African green monkey kidney cells)
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| Scientific Name |
Mus musculus [TAX:10090]
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| Lineage | Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus |
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| Evidence |
Literature
|
| Reference |
PMID: 17222058
|
| Authors |
Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K
|
| Title |
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
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| Journal |
PLoS Pathog. 2007 Jan;3(1):e5. |
| Comment |
These observations suggest that mice infected with MA15 die from an overwhelming viral infection with extensive, virally mediated destruction of pneumocytes and ciliated epithelial cells.
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| DBLINKS |
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