KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:cov00010 cov01200 cov01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:cov00010 cov01200 cov01230 cov01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:cov00010 cov00020 cov01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:cov00010 cov00020 cov00620 cov00785 cov01200 cov01210 cov01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:cov00020 cov01200 cov01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:cov00020 cov01200 cov01210 cov01230 cov01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:cov00020 cov01200 cov01210 cov01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:cov00030 cov01200 cov01100 cov01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:cov00030 cov01200 cov01100 cov01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:cov00030 cov01200 cov01230 cov01100 cov01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:cov00030 cov00230 cov01200 cov01230 cov01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH:cov00030 cov01200 cov01100 cov01120]

Other carbohydrate metabolism
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:cov00500 cov01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:cov00520 cov01250 cov01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:cov00520 cov01250 cov01100]
M00012 Glyoxylate cycle [PATH:cov00630 cov01200 cov01100 cov01110]

Energy metabolism
Carbon fixation
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:cov00430 cov00620 cov01200 cov01100 cov01120]

Methane metabolism
Nitrogen metabolism
M00530 Dissimilatory nitrate reduction, nitrate => ammonia [PATH:cov00910 cov01100 cov01120]
M00529 Denitrification, nitrate => nitrogen [PATH:cov00910 cov01100 cov01120]

Sulfur metabolism
M00176 Assimilatory sulfate reduction, sulfate => H2S [PATH:cov00920 cov01100 cov01120]

Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:cov00190 cov01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:cov00190 cov01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:cov00190 cov01100]
M00153 Cytochrome bd ubiquinol oxidase [PATH:cov00190]
M00156 Cytochrome c oxidase, cbb3-type [PATH:cov00190 cov01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:cov00190 cov01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:cov00061 cov01212 cov01100]
M00083 Fatty acid biosynthesis, elongation [PATH:cov00061 cov01212 cov01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:cov00061 cov00071 cov01212 cov01100]
M00087 beta-Oxidation [PATH:cov00071 cov01212 cov01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:cov00564 cov01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cov00230 cov01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cov00230 cov01232 cov01240 cov01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cov00230 cov01232 cov01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cov00230 cov00240 cov01232 cov01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:cov00230 cov01232 cov01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:cov00230 cov01232 cov01100]

Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:cov00260 cov00680 cov01200 cov01230 cov01100]
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:cov00260 cov01230 cov01100 cov01110]
M00621 Glycine cleavage system [PATH:cov00260 cov00630 cov00785 cov01200 cov01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:cov00260 cov01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:cov00270 cov00920 cov01200 cov01230 cov01100 cov01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:cov00270 cov01230 cov01100]

Branched-chain amino acid metabolism
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:cov00290 cov01210 cov01230 cov01100 cov01110]
M00036 Leucine degradation, leucine => acetoacetate + acetyl-CoA [PATH:cov00280 cov01100]

Lysine metabolism
M00016 Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine [PATH:cov00300 cov01230 cov01100]

Arginine and proline metabolism
M00028 Ornithine biosynthesis, glutamate => ornithine [PATH:cov00220 cov01210 cov01230 cov01100]
M00844 Arginine biosynthesis, ornithine => arginine [PATH:cov00220 cov01230 cov01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:cov00330 cov01230 cov01100]
M00970 Proline degradation, proline => glutamate [PATH:cov00330 cov01100]

Polyamine biosynthesis
M00133 Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine [PATH:cov00330 cov01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:cov00340 cov01230 cov01100 cov01110]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:cov00400 cov01230 cov01100 cov01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:cov00400 cov01230 cov01100 cov01110]

Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:cov00540 cov01250 cov01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:cov00740 cov01240 cov01100 cov01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:cov00750 cov01240 cov01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:cov00760 cov01240 cov01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:cov00770 cov01240 cov01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:cov00780 cov01240 cov01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:cov00785 cov01240 cov01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:cov00790 cov00670 cov01240 cov01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:cov00790 cov01240 cov01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:cov00860 cov01240 cov01100 cov01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:cov00860 cov01240 cov01100 cov01110]
M00122 Cobalamin biosynthesis, cobyrinate a,c-diamide => cobalamin [PATH:cov00860 cov01240 cov01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:cov00521 cov00523 cov00541 cov01250 cov01100 cov01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity