KEGG Modules
Pathway modules
Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH: pra00010 pra01200 pra01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH: pra00010 pra01200 pra01230 pra01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH: pra00010 pra00020 pra01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH: pra00010 pra00020 pra00620 pra00785 pra01200 pra01210 pra01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH: pra00020 pra01200 pra01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH: pra00020 pra01200 pra01210 pra01230 pra01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH: pra00020 pra01200 pra01210 pra01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH: pra00030 pra01200 pra01100 pra01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH: pra00030 pra01200 pra01100 pra01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH: pra00030 pra01200 pra01230 pra01100 pra01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH: pra00030 pra00230 pra01200 pra01230 pra01100]
M00008 Entner-Doudoroff pathway, glucose-6P => glyceraldehyde-3P + pyruvate [PATH: pra00030 pra01200 pra01100 pra01120]
Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH: pra00040 pra01100]
M00631 D-Galacturonate degradation (bacteria), D-galacturonate => pyruvate + D-glyceraldehyde 3P [PATH: pra00040 pra00030 pra01100]
M00061 D-Glucuronate degradation, D-glucuronate => pyruvate + D-glyceraldehyde 3P [PATH: pra00040 pra00030 pra01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH: pra00052 pra01100]
M00552 D-galactonate degradation, De Ley-Doudoroff pathway, D-galactonate => glycerate-3P [PATH: pra00052 pra01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH: pra00040 pra00053 pra01240 pra01100]
M00550 Ascorbate degradation, ascorbate => D-xylulose-5P [PATH: pra00053 pra01100 pra01120]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH: pra00500 pra01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH: pra00500 pra01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH: pra00520 pra01250 pra01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH: pra00520 pra00052 pra01250 pra01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH: pra00520 pra01250 pra01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH: pra00520 pra01250 pra01100]
M00013 Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA [PATH: pra00640 pra01200 pra01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH: pra00280 pra00630 pra00640 pra01200 pra01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH: pra01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH: pra01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH: pra01100]
Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
Lipid metabolism
Fatty acid metabolism
Sterol biosynthesis
M00101 Cholesterol biosynthesis, FPP => cholesterol [PATH: pra01100]
M00103 Cholecalciferol biosynthesis [PATH: pra01100]
M00862 beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA [PATH: pra01100]
M00107 Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone [PATH: pra01100]
M00109 C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone [PATH: pra01100]
M00110 C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone [PATH: pra01100]
M00976 C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone [PATH: pra01100]
M00977 C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone [PATH: pra01100]
Lipid metabolism
Nucleotide metabolism
Purine metabolism
Pyrimidine metabolism
Amino acid metabolism
Serine and threonine metabolism
Cysteine and methionine metabolism
Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
Polyamine biosynthesis
Histidine metabolism
Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH: pra00400 pra01230 pra01100 pra01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH: pra00400 pra01230 pra01100 pra01110]
M00024 Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine [PATH: pra00400 pra01230 pra01100 pra01110]
M00025 Tyrosine biosynthesis, chorismate => HPP => tyrosine [PATH: pra00400 pra01230 pra01100]
M00042 Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline [PATH: pra00350 pra01100]
M00043 Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [PATH: pra00350 pra01100]
M00044 Tyrosine degradation, tyrosine => homogentisate [PATH: pra00350 pra01100]
M00533 Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate [PATH: pra00350 pra01220 pra01100 pra01120]
M00037 Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin [PATH: pra00380 pra01100]
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH: pra00380 pra01100]
Other amino acid metabolism
Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH: pra01100]
M00073 N-glycan precursor trimming [PATH: pra01100]
M00075 N-glycan biosynthesis, complex type [PATH: pra01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH: pra00515 pra01100]
M00065 GPI-anchor biosynthesis, core oligosaccharide [PATH: pra01100]
M00070 Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer [PATH: pra01100]
M00071 Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer [PATH: pra01100]
M00068 Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer [PATH: pra01100]
M00069 Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3 [PATH: pra01100]
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:pra00730 pra01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:pra00740 pra01240 pra01100 pra01110]
M00124 Pyridoxal-P biosynthesis, erythrose-4P => pyridoxal-P [PATH:pra00750 pra01240 pra01100]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:pra00750 pra01240 pra01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:pra00760 pra01240 pra01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:pra00380 pra00760 pra01240 pra01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:pra00770 pra01240 pra01100 pra01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:pra00770 pra01240 pra01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:pra00780 pra01240 pra01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:pra00780 pra01240 pra01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:pra00785 pra01240 pra01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:pra00785 pra01240 pra01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:pra00785 pra01240 pra01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:pra00790 pra00670 pra01240 pra01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:pra00790 pra01240 pra01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:pra00790 pra01240 pra01100]
M00140 C1-unit interconversion, prokaryotes [PATH:pra00670 pra01240 pra01100]
M00141 C1-unit interconversion, eukaryotes [PATH:pra00670 pra01240 pra01100]
M00846 Siroheme biosynthesis, glutamyl-tRNA => siroheme [PATH:pra00860 pra01240 pra01100 pra01110]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:pra00860 pra01240 pra01100 pra01110]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:pra00860 pra01240 pra01100 pra01110]
M00117 Ubiquinone biosynthesis, prokaryotes, chorismate (+ polyprenyl-PP) => ubiquinol [PATH:pra00130 pra01240 pra01100 pra01110]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:pra00130 pra01240 pra01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:pra00130 pra01240 pra01100 pra01110]
Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Signature modules
Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity
M00616 Sulfate-sulfur assimilation
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