KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [PATH:sah00010 sah01200 sah01100]
M00002 Glycolysis, core module involving three-carbon compounds [PATH:sah00010 sah01200 sah01230 sah01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:sah00010 sah00020 sah01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:sah00010 sah00020 sah00620 sah00785 sah01200 sah01210 sah01100]
M00009 Citrate cycle (TCA cycle, Krebs cycle) [PATH:sah00020 sah01200 sah01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:sah00020 sah01200 sah01210 sah01230 sah01100]
M00011 Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate [PATH:sah00020 sah01200 sah01210 sah01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:sah00030 sah01200 sah01100 sah01120]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:sah00030 sah01200 sah01100 sah01120]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:sah00030 sah01200 sah01230 sah01100 sah01120]
M00580 Pentose phosphate pathway, archaea, fructose 6P => ribose 5P [PATH:sah00030 sah01200 sah01230 sah01100 sah01120]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:sah00030 sah00230 sah01200 sah01230 sah01100]
M00633 Semi-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate-3P [PATH:sah00030 sah00052 sah01200 sah01100]
M00309 Non-phosphorylative Entner-Doudoroff pathway, gluconate/galactonate => glycerate [PATH:sah00030 sah00052 sah01200 sah01100 sah01120]

Other carbohydrate metabolism
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:sah00520 sah01250 sah01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:sah00520 sah00052 sah01250 sah01100]
M00909 UDP-N-acetyl-D-glucosamine biosynthesis, prokaryotes, glucose => UDP-GlcNAc [PATH:sah00520 sah01250 sah01100]
M00012 Glyoxylate cycle [PATH:sah00630 sah01200 sah01100 sah01110]

Energy metabolism
Carbon fixation
M00168 CAM (Crassulacean acid metabolism), dark [PATH:sah00620 sah01200 sah01100 sah01120]
M00579 Phosphate acetyltransferase-acetate kinase pathway, acetyl-CoA => acetate [PATH:sah00430 sah00620 sah01200 sah01100 sah01120]

Methane metabolism
M00345 Formaldehyde assimilation, ribulose monophosphate pathway [PATH:sah00030 sah00680 sah01200 sah01230 sah01100 sah01120]

Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00149 Succinate dehydrogenase, prokaryotes [PATH:sah00190 sah01100]
M00155 Cytochrome c oxidase, prokaryotes [PATH:sah00190 sah01100]
M00416 Cytochrome aa3-600 menaquinol oxidase [PATH:sah00190 sah01100]
M00156 Cytochrome c oxidase, cbb3-type [PATH:sah00190 sah01100]
M00157 F-type ATPase, prokaryotes and chloroplasts [PATH:sah00190 sah01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:sah00061 sah01212 sah01100]
M00083 Fatty acid biosynthesis, elongation [PATH:sah00061 sah01212 sah01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:sah00061 sah00071 sah01212 sah01100]

Sterol biosynthesis
Lipid metabolism
M00093 Phosphatidylethanolamine (PE) biosynthesis, PA => PS => PE [PATH:sah00564 sah01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sah00230 sah01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sah00230 sah01232 sah01240 sah01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sah00230 sah01232 sah01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sah00230 sah00240 sah01232 sah01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:sah00240 sah01240 sah01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:sah00240 sah01232 sah01240 sah01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:sah00240 sah01232 sah01100]

Amino acid metabolism
Serine and threonine metabolism
M00018 Threonine biosynthesis, aspartate => homoserine => threonine [PATH:sah00260 sah01230 sah01100 sah01110]
M00621 Glycine cleavage system [PATH:sah00260 sah00630 sah00785 sah01200 sah01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:sah00260 sah01100]

Cysteine and methionine metabolism
M00021 Cysteine biosynthesis, serine => cysteine [PATH:sah00270 sah00920 sah01200 sah01230 sah01100 sah01110]
M00017 Methionine biosynthesis, aspartate => homoserine => methionine [PATH:sah00270 sah01230 sah01100]

Branched-chain amino acid metabolism
M00019 Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine [PATH:sah00290 sah00770 sah01210 sah01230 sah01100 sah01110]
M00570 Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine [PATH:sah00290 sah01230 sah01100]
M00432 Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate [PATH:sah00290 sah01210 sah01230 sah01100 sah01110]

Lysine metabolism
M00527 Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine [PATH:sah00300 sah01230 sah01100 sah01110]

Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:sah00220 sah01230 sah01100]
M00970 Proline degradation, proline => glutamate [PATH:sah00330 sah01100]
M00972 Proline metabolism [PATH:sah00330 sah01100]

Polyamine biosynthesis
Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:sah00340 sah01230 sah01100 sah01110]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:sah00340 sah01100]

Aromatic amino acid metabolism
M00022 Shikimate pathway, phosphoenolpyruvate + erythrose-4P => chorismate [PATH:sah00400 sah01230 sah01100 sah01110]
M00023 Tryptophan biosynthesis, chorismate => tryptophan [PATH:sah00400 sah01230 sah01100 sah01110]

Other amino acid metabolism
M00949 Staphylopine biosynthesis, L-histidine => staphylopine [PATH:sah00470 sah01100]

Glycan metabolism
Glycan biosynthesis
Glycosaminoglycan metabolism
Lipopolysaccharide metabolism
M00063 CMP-KDO biosynthesis [PATH:sah01250 sah01100]

Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00899 Thiamine salvage pathway, HMP/HET => TMP [PATH:sah00730 sah01100]
M00125 Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:sah00740 sah01240 sah01100 sah01110]
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:sah00750 sah01240 sah01100]
M00115 NAD biosynthesis, aspartate => quinolinate => NAD [PATH:sah00760 sah01240 sah01100]
M00119 Pantothenate biosynthesis, valine/L-aspartate => pantothenate [PATH:sah00770 sah01240 sah01100 sah01110]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:sah00770 sah01240 sah01100]
M00123 Biotin biosynthesis, pimeloyl-ACP/CoA => biotin [PATH:sah00780 sah01240 sah01100]
M00577 Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin [PATH:sah00780 sah01240 sah01100]
M00881 Lipoic acid biosynthesis, plants and bacteria, octanoyl-ACP => dihydrolipoyl-E2/H [PATH:sah00785 sah01240 sah01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:sah00785 sah01240 sah01100]
M00126 Tetrahydrofolate biosynthesis, GTP => THF [PATH:sah00790 sah00670 sah01240 sah01100]
M00880 Molybdenum cofactor biosynthesis, GTP => molybdenum cofactor [PATH:sah00790 sah01240 sah01100]
M00140 C1-unit interconversion, prokaryotes [PATH:sah00670 sah01240 sah01100]
M00121 Heme biosynthesis, plants and bacteria, glutamate => heme [PATH:sah00860 sah01240 sah01100 sah01110]
M00926 Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme [PATH:sah00860 sah01240 sah01100]
M00116 Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol [PATH:sah00130 sah01240 sah01100 sah01110]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:sah00900 sah01100 sah01110]
M00364 C10-C20 isoprenoid biosynthesis, bacteria [PATH:sah00900 sah01100 sah01110]
M00365 C10-C20 isoprenoid biosynthesis, archaea [PATH:sah00900 sah01100 sah01110]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
M00793 dTDP-L-rhamnose biosynthesis [PATH:sah00521 sah00541 sah01250 sah01100 sah01110]

Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
M00876 Staphyloferrin A biosynthesis, L-ornithine => staphyloferrin A [PATH:sah00997 sah01100 sah01110]
M00875 Staphyloferrin B biosynthesis, L-serine => staphyloferrin B [PATH:sah00997 sah01100 sah01110]

Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
M00625 Methicillin resistance [PATH:sah01501]
M00627 beta-Lactam resistance, Bla system [PATH:sah01501]
M00704 Tetracycline resistance, efflux pump Tet38
M00725 Cationic antimicrobial peptide (CAMP) resistance, dltABCD operon [PATH:sah01503]
M00726 Cationic antimicrobial peptide (CAMP) resistance, lysyl-phosphatidylglycerol (L-PG) synthase MprF [PATH:sah01503]
M00730 Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter [PATH:sah01503]
M00700 Multidrug resistance, efflux pump AbcA
M00702 Multidrug resistance, efflux pump NorB
M00705 Multidrug resistance, efflux pump MepA

Plant pathogenicity
Symbiosis
Module set
Metabolic capacity