KEGG Modules

Carbohydrate metabolism
Central carbohydrate metabolism
M00002 Glycolysis, core module involving three-carbon compounds [PATH:spis00010 spis01200 spis01230 spis01100]
M00003 Gluconeogenesis, oxaloacetate => fructose-6P [PATH:spis00010 spis00020 spis01100]
M00307 Pyruvate oxidation, pyruvate => acetyl-CoA [PATH:spis00010 spis00020 spis00620 spis00785 spis01200 spis01210 spis01100]
M00010 Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate [PATH:spis00020 spis01200 spis01210 spis01230 spis01100]
M00004 Pentose phosphate pathway (Pentose phosphate cycle) [PATH:spis00030 spis01200 spis01100]
M00006 Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P [PATH:spis00030 spis01200 spis01100]
M00007 Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P [PATH:spis00030 spis01200 spis01230 spis01100]
M00005 PRPP biosynthesis, ribose 5P => PRPP [PATH:spis00030 spis00230 spis01200 spis01230 spis01100]

Other carbohydrate metabolism
M00014 Glucuronate pathway (uronate pathway) [PATH:spis00040 spis01100]
M00632 Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P [PATH:spis00052 spis01100]
M00129 Ascorbate biosynthesis, animals, glucose-1P => ascorbate [PATH:spis00040 spis00053 spis01240 spis01100]
M00854 Glycogen biosynthesis, glucose-1P => glycogen/starch [PATH:spis00500 spis01100]
M00855 Glycogen degradation, glycogen => glucose-6P [PATH:spis00500 spis01100]
M00549 Nucleotide sugar biosynthesis, glucose => UDP-glucose [PATH:spis00520 spis01250 spis01100]
M00554 Nucleotide sugar biosynthesis, galactose => UDP-galactose [PATH:spis00520 spis00052 spis01250 spis01100]
M00892 UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc [PATH:spis00520 spis01250 spis01100]
M00741 Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:spis00280 spis00630 spis00640 spis01200 spis01100]
M00130 Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:spis00562 spis01100]
M00131 Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:spis00562 spis01100]
M00132 Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:spis00562 spis01100]

Energy metabolism
Carbon fixation
Methane metabolism
Nitrogen metabolism
Sulfur metabolism
Photosynthesis
ATP synthesis
M00148 Succinate dehydrogenase (ubiquinone) [PATH:spis00190 spis01100]
M00151 Cytochrome bc1 complex respiratory unit [PATH:spis00190 spis01100]

Lipid metabolism
Fatty acid metabolism
M00082 Fatty acid biosynthesis, initiation [PATH:spis00061 spis01212 spis01100]
M00083 Fatty acid biosynthesis, elongation [PATH:spis00061 spis01212 spis01100]
M00085 Fatty acid elongation in mitochondria [PATH:spis00062 spis01212 spis01100]
M00415 Fatty acid elongation in endoplasmic reticulum [PATH:spis00062 spis01040 spis01212 spis01100]
M00086 beta-Oxidation, acyl-CoA synthesis [PATH:spis00061 spis00071 spis01212 spis01100]
M00087 beta-Oxidation [PATH:spis00071 spis01212 spis01100]
M00861 beta-Oxidation, peroxisome, VLCFA [PATH:spis01040 spis01212 spis01100]

Sterol biosynthesis
Lipid metabolism
M00089 Triacylglycerol biosynthesis [PATH:spis00561 spis01100]
M00098 Acylglycerol degradation [PATH:spis00561 spis01100]
M00090 Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:spis00564 spis01100]
M00091 Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:spis00564 spis01100]
M00092 Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:spis00564 spis01100]
M00094 Ceramide biosynthesis [PATH:spis00600 spis01100]
M00099 Sphingosine biosynthesis [PATH:spis00600 spis01100]
M00100 Sphingosine degradation [PATH:spis00600 spis01100]

Nucleotide metabolism
Purine metabolism
M00048 De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:spis00230 spis01100]
M00049 Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:spis00230 spis01232 spis01240 spis01100]
M00050 Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:spis00230 spis01232 spis01100]
M00053 Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:spis00230 spis00240 spis01232 spis01100]
M00958 Adenine ribonucleotide degradation, AMP => Urate [PATH:spis00230 spis01232 spis01100]
M00959 Guanine ribonucleotide degradation, GMP => Urate [PATH:spis00230 spis01232 spis01100]

Pyrimidine metabolism
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:spis00240 spis01240 spis01100]
M00052 Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:spis00240 spis01232 spis01240 spis01100]
M00938 Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:spis00240 spis01232 spis01100]
M00046 Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:spis00240 spis00410 spis00770 spis01100]

Amino acid metabolism
Serine and threonine metabolism
M00020 Serine biosynthesis, glycerate-3P => serine [PATH:spis00260 spis01200 spis01230 spis01100]
M00621 Glycine cleavage system [PATH:spis00260 spis00630 spis00785 spis01200 spis01100]
M00555 Betaine biosynthesis, choline => betaine [PATH:spis00260 spis01100]
M00974 Betaine metabolism, animals, betaine => glycine [PATH:spis00260 spis01100]

Cysteine and methionine metabolism
M00338 Cysteine biosynthesis, homocysteine + serine => cysteine [PATH:spis00260 spis00270 spis01230 spis01100]
M00034 Methionine salvage pathway [PATH:spis00270 spis01100]
M00035 Methionine degradation [PATH:spis00270 spis01100]

Branched-chain amino acid metabolism
Lysine metabolism
Arginine and proline metabolism
M00844 Arginine biosynthesis, ornithine => arginine [PATH:spis00220 spis01230 spis01100]
M00029 Urea cycle [PATH:spis00220 spis01230 spis01100]
M00015 Proline biosynthesis, glutamate => proline [PATH:spis00330 spis01230 spis01100]
M00970 Proline degradation, proline => glutamate [PATH:spis00330 spis01100]
M00972 Proline metabolism [PATH:spis00330 spis01100]
M00047 Creatine pathway [PATH:spis00330 spis00260 spis01100]

Polyamine biosynthesis
M00134 Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:spis00330 spis01100]
M00135 GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:spis00330 spis01100]

Histidine metabolism
M00026 Histidine biosynthesis, PRPP => histidine [PATH:spis00340 spis01230 spis01100]
M00045 Histidine degradation, histidine => N-formiminoglutamate => glutamate [PATH:spis00340 spis01100]

Aromatic amino acid metabolism
M00038 Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate [PATH:spis00380 spis01100]

Other amino acid metabolism
M00118 Glutathione biosynthesis, glutamate => glutathione [PATH:spis00480 spis01240 spis01100]

Glycan metabolism
Glycan biosynthesis
M00055 N-glycan precursor biosynthesis [PATH:spis00510 spis01100]
M00073 N-glycan precursor trimming [PATH:spis00510 spis01100]
M00872 O-glycan biosynthesis, mannose type (core M3) [PATH:spis00515 spis01100]

Glycosaminoglycan metabolism
M00057 Glycosaminoglycan biosynthesis, linkage tetrasaccharide [PATH:spis00532 spis00534 spis01100]
M00058 Glycosaminoglycan biosynthesis, chondroitin sulfate backbone [PATH:spis00532 spis01100]
M00059 Glycosaminoglycan biosynthesis, heparan sulfate backbone [PATH:spis00534 spis01100]
M00076 Dermatan sulfate degradation [PATH:spis00531 spis01100]
M00077 Chondroitin sulfate degradation [PATH:spis00531 spis01100]
M00079 Keratan sulfate degradation [PATH:spis00531 spis01100]

Lipopolysaccharide metabolism
Metabolism of cofactors and vitamins
Cofactor and vitamin metabolism
M00916 Pyridoxal-P biosynthesis, R5P + glyceraldehyde-3P + glutamine => pyridoxal-P [PATH:spis00750 spis01240 spis01100]
M00912 NAD biosynthesis, tryptophan => quinolinate => NAD [PATH:spis00380 spis00760 spis01240 spis01100]
M00120 Coenzyme A biosynthesis, pantothenate => CoA [PATH:spis00770 spis01240 spis01100]
M00882 Lipoic acid biosynthesis, eukaryotes, octanoyl-ACP => dihydrolipoyl-H [PATH:spis00785 spis01240 spis01100]
M00883 Lipoic acid biosynthesis, animals and bacteria, octanoyl-ACP => dihydrolipoyl-H => dihydrolipoyl-E2 [PATH:spis00785 spis01240 spis01100]
M00842 Tetrahydrobiopterin biosynthesis, GTP => BH4 [PATH:spis00790 spis01240 spis01100]
M00141 C1-unit interconversion, eukaryotes [PATH:spis00670 spis01240 spis01100]
M00868 Heme biosynthesis, animals and fungi, glycine => heme [PATH:spis00860 spis01240 spis01100]
M00128 Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinol [PATH:spis00130 spis01240 spis01100]

Biosynthesis of terpenoids and polyketides
Terpenoid backbone biosynthesis
M00095 C5 isoprenoid biosynthesis, mevalonate pathway [PATH:spis00900 spis01100]
M00367 C10-C20 isoprenoid biosynthesis, non-plant eukaryotes [PATH:spis00900 spis01100]

Plant terpenoid biosynthesis
Macrolide biosynthesis
Enediyne biosynthesis
Type II polyketide biosynthesis
Polyketide sugar unit biosynthesis
Biosynthesis of other secondary metabolites
Biosynthesis of phytochemical compounds
Biosynthesis of beta-lactams
Biosynthesis of other antibiotics
Biosynthesis of other fungal compounds
Biosynthesis of other bacterial compounds
Xenobiotics biodegradation
Aromatics degradation

Gene set
Pathogenicity
Drug resistance
Plant pathogenicity
Symbiosis
Module set
Metabolic capacity