KNApSAcK Metabolite C00001176
Metabolite
KNApSAcK Entry
| id | C00001176 |
|---|---|
| Name | Acetic acid |
| CAS RN | 64-19-7 |
| Standard InChI | InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4) |
| Standard InChI (Main Layer) | InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 8271 |
Link
ChEMBL
| By standard InChI | CHEMBL539 |
|---|---|
| By standard InChI Main Layer | CHEMBL539 |
KEGG
| By LinkDB | C00033 |
|---|
CTD
| By CAS RN | D019342 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| asterids | 3 |
Family
| family name | count |
|---|---|
| Oleaceae | 1 |
| Enterobacteriaceae | 1 |
| Convolvulaceae | 1 |
| Solanaceae | 1 |
List (4)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Cuscuta chinensis | 267557 | Convolvulaceae | asterids | Viridiplantae |
| Escherichia coli KO11 | 595495 | Enterobacteriaceae | Bacteria | |
| Mandragora autumnalis | 389206 | Solanaceae | asterids | Viridiplantae |
| Olea europaea | 4146 | Oleaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
6 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | CHEMBL539 |
CHEMBL2077203
(1)
CHEMBL2077316
(1)
CHEMBL2077326 (1) |
0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL539 |
CHEMBL682779
(1)
|
0 / 0 |
| Q9UGP5 | DNA polymerase lambda | Enzyme | CHEMBL539 |
CHEMBL1921596
(1)
CHEMBL1920071
(1)
|
0 / 0 |
| O15552 | Free fatty acid receptor 2 | Free fatty acid receptor | CHEMBL539 |
CHEMBL1069216
(1)
CHEMBL1069226
(1)
|
0 / 0 |
| P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL539 |
CHEMBL823225
(2)
|
0 / 1 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | CHEMBL539 |
CHEMBL1921592
(1)
CHEMBL1921595
(1)
|
0 / 0 |
CTD interaction (5)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| D019342 | 1571 |
CYP2E1
CPE1 CYP2E P450-J P450C2E |
cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | CYP2E1 protein results in increased metabolism of Acetic Acid analog |
increases metabolic processing
|
protein |
21933969
|
| D019342 | 1786 |
DNMT1
ADCADN AIM CXXC9 DNMT HSN1E MCMT |
DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) | Acetic Acid results in decreased expression of DNMT1 protein |
decreases expression
|
protein |
17065238
|
| D019342 | 2571 |
GAD1
CPSQ1 GAD SCP |
glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15) | Acetic Acid results in increased expression of GAD1 mRNA |
increases expression
|
mRNA |
17065238
|
| D019342 | 5447 |
POR
CPR CYPOR P450R |
P450 (cytochrome) oxidoreductase (EC:1.6.2.4) | POR protein results in increased metabolism of Acetic Acid analog |
increases metabolic processing
|
protein |
21933969
|
| D019342 | 5649 |
RELN
LIS2 PRO1598 RL |
reelin | Acetic Acid results in increased expression of RELN mRNA |
increases expression
|
mRNA |
17065238
|