Escherichia coli KO11

• Index
• Plant Species
• Metabolite list (4)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Escherichia coli KO11
Genus	Escherichia
Family	Enterobacteriaceae
Kingdom

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Escherichia coli KO11FL
Linked NCBI taxonomy ID	595495
Linked level	no rank

Family

Family in NCBI taxonomy	Enterobacteriaceae
ID	543

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Bacteria
ID	2

Plant class

Plant class
ID

Metabolite list (4)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00007392	Acetaldehyde / Acetic aldehyde	CHEMBL170365	D000079	2 / 8 / 5	126 / 15	No. 7289
C00001176	Acetic acid	CHEMBL539	D019342	6 / 0 / 1	5 / 14	No. 8271
C00019559	Acetyl phosphate		C011632			No. 8442
C00019560	Ethanol	CHEMBL545	D000431	92 / 39 / 33	199 / 193	No. 8862

Human Protein / Gene in interactions

97 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16473	Thyrotropin receptor	Glycohormone receptor	C00007392 C00019560	3 / 2
P06239	Tyrosine-protein kinase Lck	Src	C00001176 C00019560	0 / 1
P06241	Tyrosine-protein kinase Fyn	Src	C00001176 C00019560	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00019560	0 / 0
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00019560	2 / 2
P08246	Neutrophil elastase	S1A	C00019560	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00019560	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00019560	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00019560	0 / 0
P29466	Caspase-1	C14	C00019560	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00019560	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00019560	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00019560	2 / 2
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00019560	1 / 0
P00918	Carbonic anhydrase 2	Lyase	C00019560	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00019560	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00019560	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00019560	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00019560	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00019560	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00019560	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00019560	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00019560	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00019560	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00019560	0 / 1
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00019560	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00019560	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00019560	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00019560	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00019560	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00019560	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00019560	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00019560	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00019560	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00019560	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00019560	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00019560	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00019560	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00019560	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00019560	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00019560	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00019560	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00019560	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00019560	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00019560	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00019560	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00019560	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00019560	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00019560	0 / 0
P08311	Cathepsin G	S1A	C00019560	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00019560	1 / 0
P03956	Interstitial collagenase	M10A	C00019560	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00019560	0 / 0
Q9UGP5	DNA polymerase lambda	Enzyme	C00001176	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00019560	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00019560	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00019560	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00019560	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00019560	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00007392	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00019560	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00019560	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00019560	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00019560	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00019560	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00019560	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00019560	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00019560	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00019560	2 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00019560	0 / 3
P51449	Nuclear receptor ROR-gamma	Nuclear hormone receptor subfamily 1 group F member 3	C00019560	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00019560	0 / 0
P03372	Estrogen receptor	NR3A1	C00019560	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00019560	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00019560	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00019560	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00019560	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00019560	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00019560	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00019560	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00019560	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00019560	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00019560	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00019560	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00019560	0 / 0
O15552	Free fatty acid receptor 2	Free fatty acid receptor	C00001176	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00019560	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00019560	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00019560	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00019560	1 / 1
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001176	0 / 0
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00019560	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00001176	0 / 0

290 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001176 C00007392 C00019560
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00007392 C00019560
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00007392 C00019560
126	ADH1C, ADH3	alcohol dehydrogenase 1C (class I), gamma polypeptide (EC:1.1.1.1)	C00007392 C00019560
127	ADH4, ADH-2	alcohol dehydrogenase 4 (class II), pi polypeptide (EC:1.1.1.1)	C00007392 C00019560
7082	TJP1, ZO-1	tight junction protein 1	C00007392 C00019560
7040	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta	transforming growth factor, beta 1	C00007392 C00019560
6720	SREBF1, SREBP-1c, SREBP1, bHLHd1	sterol regulatory element binding transcription factor 1	C00007392 C00019560
217	ALDH2, ALDH-E2, ALDHI, ALDM	aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3)	C00007392 C00019560
6696	SPP1, BNSP, BSPI, ETA-1, OPN	secreted phosphoprotein 1	C00007392 C00019560
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00007392 C00019560
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00007392 C00019560
5580	PRKCD, MAY1, PKCD, nPKC-delta	protein kinase C, delta (EC:2.7.10.2 2.7.11.13)	C00007392 C00019560
5579	PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2	protein kinase C, beta (EC:2.7.11.13)	C00007392 C00019560
581	BAX, BCL2L4	BCL2-associated X protein	C00007392 C00019560
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00007392 C00019560
5468	PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma	peroxisome proliferator-activated receptor gamma	C00007392 C00019560
5465	PPARA, NR1C1, PPAR, PPARalpha, hPPAR	peroxisome proliferator-activated receptor alpha	C00007392 C00019560
5335	PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1	phospholipase C, gamma 1 (EC:3.1.4.11)	C00007392 C00019560
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00007392 C00019560
847	CAT	catalase (EC:1.11.1.6)	C00007392 C00019560
100506658	OCLN, BLCPMG	occludin (EC:2.1.1.67)	C00007392 C00019560
4843	NOS2, HEP-NOS, INOS, NOS, NOS2A	nitric oxide synthase 2, inducible (EC:1.14.13.39)	C00007392 C00019560
4791	NFKB2, H2TF1, LYT-10, LYT10, NF-kB2, p105, p52	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	C00007392 C00019560
4790	NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	C00007392 C00019560
4313	MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24)	C00007392 C00019560
4144	MAT2A, MATA2, MATII, SAMS2	methionine adenosyltransferase II, alpha (EC:2.5.1.6)	C00007392 C00019560
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00007392 C00019560
1278	COL1A2, OI4	collagen, type I, alpha 2	C00007392 C00019560
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00007392 C00019560
3708	ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29	inositol 1,4,5-trisphosphate receptor, type 1	C00007392 C00019560
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00007392 C00019560
1536	CYBB, AMCBX2, CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX	cytochrome b-245, beta polypeptide	C00007392 C00019560
125	ADH1B, ADH2	alcohol dehydrogenase 1B (class I), beta polypeptide (EC:1.1.1.1)	C00007392 C00019560
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00007392 C00019560
57817	HAMP, HEPC, HFE2B, LEAP1, PLTR	hepcidin antimicrobial peptide	C00007392 C00019560
2741	GLRA1, HKPX1, STHE	glycine receptor, alpha 1	C00007392 C00019560
2335	FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF	fibronectin 1	C00007392 C00019560
2177	FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD	Fanconi anemia, complementation group D2	C00007392 C00019560
100136658			C00019560
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00007392
1958	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225	early growth response 1	C00007392
1950	EGF, HOMG4, URG	epidermal growth factor	C00007392
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00007392
94234	FOXQ1, HFH1	forkhead box Q1	C00007392
2597	GAPDH, G3PD, GAPD	glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12)	C00007392
100702724			C00007392
2669	GEM, KIR	GTP binding protein overexpressed in skeletal muscle	C00007392
1850	DUSP8, C11orf81, HB5, HVH-5, HVH8	dual specificity phosphatase 8 (EC:3.1.3.16 3.1.3.48)	C00007392
22943	DKK1, DKK-1, SK	dickkopf WNT signaling pathway inhibitor 1	C00007392
3280	HES1, HES-1, HHL, HRY, bHLHb39	hes family bHLH transcription factor 1	C00007392
29923	HILPDA, C7orf68, HIG-2, HIG2	hypoxia inducible lipid droplet-associated	C00007392
554219			C00007392
3586	IL10, CSIF, GVHDS, IL-10, IL10A, TGIF	interleukin 10	C00007392
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00007392
3565	IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4	interleukin 4	C00007392
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00007392
64651	CSRNP1, AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1	cysteine-serine-rich nuclear protein 1	C00007392
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00007392
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00007392
1282	COL4A1, HANAC, ICH, POREN1, arresten	collagen, type IV, alpha 1	C00007392
1277	COL1A1, OI4	collagen, type I, alpha 1	C00007392
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00007392
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00007392
728577	CNTNAP3B	contactin associated protein-like 3B	C00007392
153364	MBLAC2	metallo-beta-lactamase domain containing 2	C00007392
4170	MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT	myeloid cell leukemia sequence 1 (BCL2-related)	C00007392
84981	MIR22HG, C17orf91	MIR22 host gene (non-protein coding)	C00007392
4312	MMP1, CLG, CLGN	matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7)	C00007392
4320	MMP11, SL-3, ST3, STMY3	matrix metallopeptidase 11 (stromelysin 3) (EC:3.4.24.-)	C00007392
1268	CNR1, CANN6, CB-R, CB1, CB1A, CB1K5, CB1R, CNR	cannabinoid receptor 1 (brain)	C00007392
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00007392
4353	MPO	myeloperoxidase (EC:1.11.2.2)	C00007392
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00007392
1081	CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA	glycoprotein hormones, alpha polypeptide	C00007392
729230	CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R	chemokine (C-C motif) receptor 2	C00007392
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00007392
57018	CCNL1, ANIA6A, PRO1073, ania-6a	cyclin L1	C00007392
3164	NR4A1, GFRP1, HMR, N10, NAK-1, NGFIB, NP10, NUR77, TR3	nuclear receptor subfamily 4, group A, member 1	C00007392
4929	NR4A2, HZF-3, NOT, NURR1, RNR1, TINUR	nuclear receptor subfamily 4, group A, member 2	C00007392
424046			C00007392
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00007392
4953	ODC1, ODC	ornithine decarboxylase 1 (EC:4.1.1.17)	C00007392
23035	PHLPP2, PHLPPL	PH domain and leucine rich repeat protein phosphatase 2 (EC:3.1.3.16)	C00007392
57157	PHTF2	putative homeodomain transcription factor 2	C00007392
91461	PKDCC, SGK493, Vlk	protein kinase domain containing, cytoplasmic	C00007392
57035	C1orf63, DJ465N24.2.1, NPD014, RP3-465N24.4	chromosome 1 open reading frame 63	C00007392
55629	PNRC2	proline-rich nuclear receptor coactivator 2	C00007392
283687	C15orf37	chromosome 15 open reading frame 37	C00007392
8553	BHLHE40, BHLHB2, DEC1, HLHB2, SHARP-2, STRA13, Stra14	basic helix-loop-helix family, member e40	C00007392
5514	PPP1R10, CAT53, FB19, PNUTS, PP1R10, R111, p99	protein phosphatase 1, regulatory subunit 10	C00007392
221079	ARL5B, ARL8	ADP-ribosylation factor-like 5B	C00007392
57679	ALS2, ALS2CR6, ALSJ, IAHSP, PLSJ	amyotrophic lateral sclerosis 2 (juvenile)	C00007392
5581	PRKCE, PKCE, nPKC-epsilon	protein kinase C, epsilon (EC:2.7.11.13)	C00007392
5742	PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00007392
223	ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH	aldehyde dehydrogenase 9 family, member A1 (EC:1.2.1.3 1.2.1.19 1.2.1.47)	C00007392
51655	RASD1, AGS1, DEXRAS1, MGC:26290	RAS, dexamethasone-induced 1	C00007392
221	ALDH3B1, ALDH4, ALDH7	aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5)	C00007392
5994	RFXAP	regulatory factor X-associated protein	C00007392
9886	RHOBTB1	Rho-related BTB domain containing 1	C00007392
27289	RND1, ARHS, RHO6, RHOS	Rho family GTPase 1	C00007392
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00007392
65117	RSRC2	arginine/serine-rich coiled-coil 2	C00007392
27111	SDCBP2, SITAC, SITAC18, ST-2	syndecan binding protein (syntenin) 2	C00007392
6403	SELP, CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL	selectin P (granule membrane protein 140kDa, antigen CD62)	C00007392
54093	SETD4, C21orf18, C21orf27	SET domain containing 4	C00007392
84826	SFT2D3	SFT2 domain containing 3	C00007392
387640	SKIDA1, C10orf140, DLN-1	SKI/DACH domain containing 1	C00007392
6498	SKIL, SNO, SnoA, SnoI, SnoN	SKI-like oncogene	C00007392
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00007392
4088	SMAD3, HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3	SMAD family member 3	C00007392
4089	SMAD4, DPC4, JIP, MADH4, MYHRS	SMAD family member 4	C00007392
6667	SP1	Sp1 transcription factor	C00007392
218	ALDH3A1, ALDH3, ALDHIII	aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5)	C00007392
219	ALDH1B1, ALDH5, ALDHX	aldehyde dehydrogenase 1 family, member B1 (EC:1.2.1.3)	C00007392
56977	STOX2	storkhead box 2	C00007392
216	ALDH1A1, ALDC, ALDH-E1, ALDH1, ALDH11, PUMB1, RALDH1	aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36)	C00007392
9370	ADIPOQ, ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28	adiponectin, C1Q and collagen domain containing	C00007392
25	ABL1, ABL, JTK7, bcr/abl, c-ABL, p150, v-abl	c-abl oncogene 1, non-receptor tyrosine kinase (EC:2.7.10.2)	C00007392
22888	UBOX5, RNF37, UBCE7IP5, UIP5	U-box domain containing 5	C00007392
43	ACHE, ACEE, ARACHE, N-ACHE, YT	acetylcholinesterase (EC:3.1.1.7)	C00007392
10138	YAF2	YY1 associated factor 2	C00007392
56829	ZC3HAV1, ARTD13, FLB6421, PARP13, ZAP, ZC3H2, ZC3HDC2	zinc finger CCCH-type, antiviral 1	C00007392
7539	ZFP37, ZNF906, zfp-37	ZFP37 zinc finger protein	C00007392
7769	ZNF226	zinc finger protein 226	C00007392
7310			C00007392
23536	ADAT1, HADAT1	adenosine deaminase, tRNA-specific 1 (EC:3.5.4.34)	C00019560
124	ADH1A, ADH1	alcohol dehydrogenase 1A (class I), alpha polypeptide (EC:1.1.1.1)	C00019560
128	ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR	alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284)	C00019560
131	ADH7, ADH4	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (EC:1.1.1.1)	C00019560
22977	AKR7A3, AFAR2	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	C00019560
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00019560
273	AMPH, AMPH1	amphiphysin	C00019560
162	AP1B1, ADTB1, AP105A, BAM22, CLAPB2	adaptor-related protein complex 1, beta 1 subunit	C00019560
79065	ATG9A, APG9L1, MGD3208, mATG9	autophagy related 9A	C00019560
506	ATP5B, ATPMB, ATPSB	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14)	C00019560
8678	BECN1, ATG6, VPS30, beclin1	beclin 1, autophagy related	C00019560
274	BIN1, AMPH2, AMPHL, SH3P9	bridging integrator 1	C00019560
708	C1QBP, GC1QBP, HABP1, SF2p32, gC1Q-R, gC1qR, p32	complement component 1, q subcomponent binding protein	C00019560
832	CAPZB, CAPB, CAPPB, CAPZ	capping protein (actin filament) muscle Z-line, beta	C00019560
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00019560
857	CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV	caveolin 1, caveolae protein, 22kDa	C00019560
83446	CCDC70	coiled-coil domain containing 70	C00019560
54535	CCHCR1, C6orf18, HCR, SBP	coiled-coil alpha-helical rod protein 1	C00019560
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019560
894	CCND2, KIAK0002	cyclin D2	C00019560
994	CDC25B	cell division cycle 25B (EC:3.1.3.48)	C00019560
55664	CDC37L1, CDC37B, HARC	cell division cycle 37-like 1	C00019560
1003	CDH5, 7B4, CD144	cadherin 5, type 2 (vascular endothelium)	C00019560
23552	CDK20, CCRK, CDCH, P42, PNQALRE	cyclin-dependent kinase 20 (EC:2.7.11.22)	C00019560
1050	CEBPA, C/EBP-alpha, CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	C00019560
55165	CEP55, C10orf3, CT111, URCC6	centrosomal protein 55kDa	C00019560
1066	CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1	carboxylesterase 1 (EC:3.1.1.1 3.1.1.56)	C00019560
1138	CHRNA5, LNCR2	cholinergic receptor, nicotinic, alpha 5 (neuronal)	C00019560
1140	CHRNB1, ACHRB, CHRNB, CMS1D, CMS2A, SCCMS	cholinergic receptor, nicotinic, beta 1 (muscle)	C00019560
1191	CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2	clusterin	C00019560
1266	CNN3	calponin 3, acidic	C00019560
1417	CRYBB3, CATCN2, CRYB3, CTRCT22	crystallin, beta B3	C00019560
1442	CSH1, CS-1, CSA, CSMT, PL, hCS-A	chorionic somatomammotropin hormone 1 (placental lactogen)	C00019560
1535	CYBA, p22-PHOX	cytochrome b-245, alpha polypeptide	C00019560
54541	DDIT4, Dig2, REDD-1, REDD1	DNA-damage-inducible transcript 4	C00019560
10591	DNPH1, C6orf108, RCL, RP3-330M21.3, dJ330M21.3	2'-deoxynucleoside 5'-phosphate N-hydrolase 1	C00019560
1837	DTNA, D18S892E, DRP3, DTN, DTN-A, LVNC1	dystrobrevin, alpha	C00019560
338599	DUPD1, DUSP27, FMDSP	dual specificity phosphatase and pro isomerase domain containing 1 (EC:3.1.3.16 3.1.3.48)	C00019560
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00019560
2023	ENO1, ENO1L1, MPB1, NNE, PPH	enolase 1, (alpha) (EC:4.2.1.11)	C00019560
10961	ERP29, C12orf8, ERp28, ERp31, PDI-DB, PDIA9	endoplasmic reticulum protein 29	C00019560
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00019560
84261	FBXW9, Fbw9	F-box and WD repeat domain containing 9	C00019560
2263	FGFR2, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25	fibroblast growth factor receptor 2 (EC:2.7.10.1)	C00019560
2348	FOLR1, FBP, FOLR	folate receptor 1 (adult)	C00019560
2512	FTL, NBIA3	ferritin, light polypeptide	C00019560
2526	FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, LeX, SSEA-1	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-)	C00019560
2534	FYN, SLK, SYN, p59-FYN	FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2)	C00019560
2729	GCLC, GCL, GCS, GLCL, GLCLC	glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2)	C00019560
2670	GFAP	glial fibrillary acidic protein	C00019560
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00019560
51031	GLOD4, C17orf25, HC71	glyoxalase domain containing 4	C00019560
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00019560
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00019560
2952	GSTT1	glutathione S-transferase theta 1 (EC:2.5.1.18)	C00019560
1839	HBEGF, DTR, DTS, DTSF, HEGFL	heparin-binding EGF-like growth factor	C00019560
3091	HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	C00019560
3156	HMGCR, LDLCQ3	3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34)	C00019560
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00019560
3181	HNRNPA2B1, HNRNPA2, HNRNPB1, HNRPA2, HNRPA2B1, HNRPB1, IBMPFD2, RNPA2, SNRPB1	heterogeneous nuclear ribonucleoprotein A2/B1	C00019560
3190	HNRNPK, CSBP, HNRPK, TUNP	heterogeneous nuclear ribonucleoprotein K	C00019560
3359	HTR3A, 5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3	5-hydroxytryptamine (serotonin) receptor 3A, ionotropic	C00019560
9177	HTR3B, 5-HT3B	5-hydroxytryptamine (serotonin) receptor 3B, ionotropic	C00019560
27429	HTRA2, OMI, PARK13, PRSS25	HtrA serine peptidase 2 (EC:3.4.21.108)	C00019560
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00019560
3479	IGF1, IGF-I, IGF1A, IGFI	insulin-like growth factor 1 (somatomedin C)	C00019560
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00019560
3589	IL11, AGIF, IL-11	interleukin 11	C00019560
3678	ITGA5, CD49e, FNRA, VLA5A	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	C00019560
83999	KREMEN1, KREMEN, KRM1	kringle containing transmembrane protein 1	C00019560
3875	KRT18, CYK18, K18	keratin 18	C00019560
3856	KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO	keratin 8	C00019560
3897	L1CAM, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1	L1 cell adhesion molecule	C00019560
4017	LOXL2, LOR2, WS9-14	lysyl oxidase-like 2 (EC:1.4.3.-)	C00019560
4148	MATN3, DIPOA, EDM5, HOA, OADIP, OS2	matrilin 3	C00019560
406931	MIR139, MIR139-3p, MIRN139	microRNA 139	C00019560
406987	MIR204, MIRN204, miRNA204	microRNA 204	C00019560
100126336	MIR208B, MIRN208B	microRNA 208b	C00019560
407018	MIR27A, MIR27, MIRN27A	microRNA 27a	C00019560
442894	MIR302B, MIRN302B	microRNA 302b	C00019560
693120	MIR33B, MIRN33B, hsa-mir-33b	microRNA 33b	C00019560
407040	MIR34A, MIRN34A, miRNA34A, mir-34	microRNA 34a	C00019560
442914	MIR369, MIR369-3, MIRN369, MIRN369-3, hsa-mir-369	microRNA 369	C00019560
442915	MIR370, MIRN370, hsa-mir-370	microRNA 370	C00019560
442918	MIR373, MIRN373, hsa-mir-373, miRNA373	microRNA 373	C00019560
494324	MIR375, MIRN375, hsa-mir-375, miRNA375	microRNA 375	C00019560
574451	MIR432, MIRN432, hsa-mir-432	microRNA 432	C00019560
619552	MIR483, MIRN483, hsa-mir-483	microRNA 483	C00019560
574450	MIR493, MIRN493, hsa-mir-493	microRNA 493	C00019560
574456	MIR497, MIRN497, hsa-mir-497	microRNA 497	C00019560
574472	MIR518F, MIRN518F	microRNA 518f	C00019560
574471	MIR523, MIRN523, hsa-mir-523	microRNA 523	C00019560
693191	MIR606, MIRN606, hsa-mir-606	microRNA 606	C00019560
724026	MIR656, MIRN656, hsa-mir-656	microRNA 656	C00019560
100126326	MIR936, MIRN936, hsa-mir-936	microRNA 936	C00019560
4548	MTR, HMAG, MS, cblG	5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13)	C00019560
4595	MUTYH, CYP2C, MYH	mutY homolog (EC:3.2.2.-)	C00019560
4638	MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK	myosin light chain kinase (EC:2.7.11.18)	C00019560
653361	NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox	neutrophil cytosolic factor 1	C00019560
4688	NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX	neutrophil cytosolic factor 2	C00019560
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00019560
4830	NME1, AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1	NME/NM23 nucleoside diphosphate kinase 1 (EC:2.7.4.6)	C00019560
8996	NOL3, ARC, FCM, MYP, NOP, NOP30	nucleolar protein 3 (apoptosis repressor with CARD domain)	C00019560
4854	NOTCH3, CADASIL, CASIL, IMF2	notch 3	C00019560
27035	NOX1, GP91-2, MOX1, NOH-1, NOH1	NADPH oxidase 1	C00019560
4897	NRCAM	neuronal cell adhesion molecule	C00019560
8829	NRP1, BDCA4, CD304, NP1, NRP, VEGF165R	neuropilin 1	C00019560
4968	OGG1, HMMH, HOGG1, MUTM, OGH1	8-oxoguanine DNA glycosylase (EC:4.2.99.18)	C00019560
4986	OPRK1, K-OR-1, KOR, KOR-1, OPRK	opioid receptor, kappa 1	C00019560
4988	OPRM1, LMOR, M-OR-1, MOP, MOR, MOR1, OPRM	opioid receptor, mu 1	C00019560
84876	ORAI1, CRACM1, IMD9, ORAT1, TMEM142A	ORAI calcium release-activated calcium modulator 1	C00019560
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00019560
5142	PDE4B, DPDE4, PDE4B5, PDEIVB	phosphodiesterase 4B, cAMP-specific (EC:3.1.4.17)	C00019560
5173	PDYN, ADCA, PENKB, SCA23	prodynorphin	C00019560
5179	PENK	proenkephalin	C00019560
5204	PFDN5, MM-1, MM1, PFD5	prefoldin subunit 5	C00019560
25796	PGLS, 6PGL	6-phosphogluconolactonase (EC:3.1.1.31)	C00019560
5245	PHB, PHB1	prohibitin	C00019560
26227	PHGDH, 3-PGDH, 3PGDH, PDG, PGAD, PGD, PGDH, SERA	phosphoglycerate dehydrogenase (EC:1.1.1.95)	C00019560
5352	PLOD2, LH2, TLH	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4)	C00019560
57048	PLSCR3	phospholipid scramblase 3	C00019560
5366	PMAIP1, APR, NOXA	phorbol-12-myristate-13-acetate-induced protein 1	C00019560
5395	PMS2, HNPCC4, PMS2CL, PMSL2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	C00019560
5426	POLE, CRCS12, FILS, POLE1	polymerase (DNA directed), epsilon, catalytic subunit (EC:2.7.7.7)	C00019560
5443	POMC, ACTH, CLIP, LPH, MSH, NPP, POC	proopiomelanocortin	C00019560
5451	POU2F1, OCT1, OTF1, oct-1B	POU class 2 homeobox 1	C00019560
5460	POU5F1, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4	POU class 5 homeobox 1	C00019560
1974	EIF4A2, BM-010, DDX2B, EIF4A, EIF4F, eIF-4A-II, eIF4A-II	eukaryotic translation initiation factor 4A2 (EC:3.6.4.13)	C00007392
8497	PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	C00019560
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019560
9588	PRDX6, 1-Cys, AOP2, NSGPx, PRX, aiPLA2, p29	peroxiredoxin 6 (EC:1.11.1.9 1.11.1.15)	C00019560
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00019560
2185	PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK	protein tyrosine kinase 2 beta (EC:2.7.10.2)	C00019560
5879	RAC1, Rac-1, TC-25, p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	C00019560
5884	RAD17, CCYC, HRAD17, R24L, RAD17SP, RAD24	RAD17 homolog (S. pombe)	C00019560
6236	RRAD, RAD, RAD1, REM3	Ras-related associated with diabetes	C00019560
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00019560
6342	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX	sterol carrier protein 2 (EC:2.3.1.176)	C00019560
23513	SCRIB, CRIB1, SCRB1, SCRIB1, Vartul	scribbled planar cell polarity protein	C00019560
6573	SLC19A1, CHMD, FOLT, IFC1, REFC, RFC1	solute carrier family 19 (folate transporter), member 1	C00019560
2030	SLC29A1, ENT1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	C00019560
60682	SMAP1, SMAP-1	small ArfGAP 1	C00019560
6678	SPARC, ON	secreted protein, acidic, cysteine-rich (osteonectin)	C00019560
6723	SRM, PAPT, SPDSY, SPS1, SRML1	spermidine synthase (EC:2.5.1.16)	C00019560
56910	STARD7, GTT1	StAR-related lipid transfer (START) domain containing 7	C00019560
6786	STIM1, D11S4896E, GOK, IMD10, TAM	stromal interaction molecule 1	C00019560
6817	SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1)	C00019560
6818	SULT1A3, HAST, HAST3, M-PST, ST1A3/ST1A4, ST1A5, STM, TL-PST	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3 (EC:2.8.2.1)	C00019560
6783	SULT1E1, EST, EST-1, ST1E1, STE	sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4)	C00019560
6822	SULT2A1, DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 (EC:2.8.2.14)	C00019560
9095	TBX19, TBS19, TPIT, dJ747L4.1	T-box 19	C00019560
7037	TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90	transferrin receptor	C00019560
7052	TGM2, G-ALPHA-h, GNAH, TG2, TGC	transglutaminase 2 (EC:2.3.2.13)	C00019560
7083	TK1, TK2	thymidine kinase 1, soluble (EC:2.7.1.21)	C00019560
7167	TPI1, TIM, TPI, TPID	triosephosphate isomerase 1 (EC:5.3.1.1)	C00019560
10107	TRIM10, HERF1, RFB30, RNF9	tripartite motif containing 10	C00019560
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00019560
331	XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3	X-linked inhibitor of apoptosis	C00019560
7515	XRCC1, RCC	X-ray repair complementing defective repair in Chinese hamster cells 1	C00019560
25925	ZNF521, EHZF, Evi3	zinc finger protein 521	C00019560
1786	DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT	DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37)	C00001176
2571	GAD1, CPSQ1, GAD, SCP	glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15)	C00001176
5447	POR, CPR, CYPOR, P450R	P450 (cytochrome) oxidoreductase (EC:1.6.2.4)	C00001176
5649	RELN, LIS2, PRO1598, RL	reelin	C00001176

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