| Organism name | Cuscuta chinensis | 
|---|---|
| Genus | Cuscuta | 
| Family | Convolvulaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Cuscuta chinensis | 
|---|---|
| Linked NCBI taxonomy ID | 267557 | 
| Linked level | species | 
| Family in NCBI taxonomy | Convolvulaceae | 
|---|---|
| ID | 4118 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | asterids | 
|---|---|
| ID | 71274 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00007192   | (+)-Epipinoresinol | CHEMBL267963 CHEMBL487611 CHEMBL460862 | 7 / 5 / 6 | No. 38 | No. 21 |   | ||
| C00007190   | (+)-Pinoresinol | CHEMBL267963 CHEMBL487611 CHEMBL460862 | C103298 | 7 / 5 / 6 | No. 38 | No. 21 |   | |
| C00044036   | (11S)-Jalapinolic acid | No. 184 | No. 68 |   | ||||
| C00044137   | Cuscutic acid B / (-)-Cuscutic acid B | No. 847 |   | |||||
| C00044136   | Cuscutic acid A / (-)-Cuscutic acid A | No. 847 |   | |||||
| C00044139   | Cuscutic acid D / (-)-Cuscutic acid D | No. 847 |   | |||||
| C00044138   | Cuscutic acid C / (-)-Cuscutic acid C | No. 847 |   | |||||
| C00001207   | Tiglic acid | CHEMBL55941 CHEMBL52416 | No. 5138 |   | ||||
| C00044287   | Propionic acid | CHEMBL14021 | C029658 | 3 / 0 / 0 | 0 / 2 | No. 6558 |   | |
| C00044037   | (2R,3R)-Nilic acid | No. 7691 |   | |||||
| C00001176   | Acetic acid | CHEMBL539 | D019342 | 6 / 0 / 1 | 5 / 14 | No. 8271 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00007190 C00007192 | 0 / 0 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00007190 C00007192 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00007190 C00007192 | 0 / 3 | 
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007190 C00007192 | 0 / 0 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001176 C00044287 | 0 / 0 | 
| Q9UGP5 | DNA polymerase lambda | Enzyme | C00001176 C00044287 | 0 / 0 | 
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00007190 C00007192 | 0 / 0 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00007190 C00007192 | 0 / 0 | 
| O15552 | Free fatty acid receptor 2 | Free fatty acid receptor | C00001176 C00044287 | 0 / 0 | 
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007190 C00007192 | 5 / 3 | 
| P06239 | Tyrosine-protein kinase Lck | Src | C00001176 | 0 / 1 | 
| P06241 | Tyrosine-protein kinase Fyn | Src | C00001176 | 0 / 0 | 
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001176 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) | C00001176 | 
| 1786 | DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT | DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37) | C00001176 | 
| 2571 | GAD1, CPSQ1, GAD, SCP | glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15) | C00001176 | 
| 5447 | POR, CPR, CYPOR, P450R | P450 (cytochrome) oxidoreductase (EC:1.6.2.4) | C00001176 | 
| 5649 | RELN, LIS2, PRO1598, RL | reelin | C00001176 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| %606641 | Body mass index; bmi | P37231 | 
| #609338 | Carotid intimal medial thickness 1 | P37231 | 
| #137800 | Glioma susceptibility 1; glm1 | P37231 | 
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 | P37231 | 
| #601665 | Obesity | P37231 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00093 | Combined immunodeficiencies (CIDs) | P06239
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00032 | Thyroid cancer | P37231
                            (related) | 
| H00409 | Type II diabetes mellitus | P37231
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P37231
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D001321 | Autistic Disorder | C00044287 | 
| D004342 | Drug Hypersensitivity | C00044287 | 
| D003092 | Colitis | C00001176 | 
| D004195 | Disease Models, Animal | C00001176 | 
| D006869 | Hydronephrosis | C00001176 | 
| D006930 | Hyperalgesia | C00001176 | 
| D007249 | Inflammation | C00001176 | 
| D007681 | Kidney Papillary Necrosis | C00001176 | 
| D009069 | Movement Disorders | C00001176 | 
| D009336 | Necrosis | C00001176 | 
| D010146 | Pain | C00001176 | 
| D011350 | Proctocolitis | C00001176 | 
| D011704 | Pyelonephritis | C00001176 | 
| D013276 | Stomach Ulcer | C00001176 | 
| D014456 | Ulcer | C00001176 | 
| D053201 | Urinary Bladder, Overactive | C00001176 |