PCIDB

KNApSAcK Metabolite C00001835

Metabolite

KNApSAcK Entry

id C00001835
Name Cephaeline
CAS RN 483-17-0
Standard InChI InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20?,23+,24-/m0/s1
Standard InChI (Main Layer) InChI=1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3

Cluster

Phytochemical cluster No. 4
KCF-S cluster No. 510

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL255708 CHEMBL486005 CHEMBL1616444

KEGG

By LinkDB C09390

CTD

By CAS RN C005963

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P20701 Integrin alpha-L Membrane receptor CHEMBL255708 CHEMBL982328 (1) CHEMBL982330 (1)
0 / 0
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor CHEMBL486005 CHEMBL999922 (1) CHEMBL999923 (1)
0 / 0
P27540 Aryl hydrocarbon receptor nuclear translocator Unclassified protein CHEMBL486005 CHEMBL999908 (1) CHEMBL999909 (1)
0 / 0

CTD interaction (6)

compound gene gene name gene description interaction interaction type form reference
pmid
C005963 6347 CCL2
GDCF-2
HC11
HSMCR30
MCAF
MCP-1
MCP1
SCYA2
SMC-CF
chemokine (C-C motif) ligand 2 cephaelin results in decreased expression of CCL2 protein decreases expression
protein 20116850
C005963 6351 CCL4
ACT2
AT744.1
G-26
HC21
LAG-1
LAG1
MIP-1-beta
MIP1B
MIP1B1
SCYA2
SCYA4
chemokine (C-C motif) ligand 4 cephaelin results in decreased expression of CCL4 protein decreases expression
protein 20116850
C005963 6352 CCL5
D17S136E
RANTES
SCYA5
SIS-delta
SISd
TCP228
eoCP
chemokine (C-C motif) ligand 5 cephaelin results in decreased expression of CCL5 protein decreases expression
protein 20116850
C005963 3570 IL6R
CD126
IL-6R-1
IL-6RA
IL6Q
IL6RA
IL6RQ
gp80
interleukin 6 receptor cephaelin results in decreased expression of IL6R protein modified form decreases expression
protein 20116850
C005963 3576 IL8
CXCL8
GCP-1
GCP1
LECT
LUCT
LYNAP
MDNCF
MONAP
NAF
NAP-1
NAP1
interleukin 8 cephaelin results in decreased expression of IL8 protein decreases expression
protein 20116850
C005963 7422 VEGFA
MVCD1
VEGF
VPF
vascular endothelial growth factor A cephaelin results in decreased expression of VEGFA protein decreases expression
protein 20116850