KCF-S cluster No. 510 (16 metabolites)
Corresponding Phytochemical cluster No. 4
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| asterids | 37 |
| rosids | 12 |
Cumulative family count
| class name | count |
|---|---|
| Rubiaceae | 20 |
| Cornaceae | 17 |
| Moraceae | 12 |
KEGG BRITE br08003
Categories (1)
| br08003 Category | # of metabolite |
|---|---|
| Isoquinoline alkaloids | 7 |
metabolites link (7)
Metabolite list (16)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001778
|
Tubulosine
/ (-)-Tubulosine |
CHEMBL518568
CHEMBL535307 CHEMBL1254284 CHEMBL1369261 |
C009805
|
19 / 18 / 10 |
|
|
|
C00001795
|
Alangicine
|
|
||||
|
C00001796
|
Alangimarckine
|
|
||||
|
C00001835
|
Cephaeline
|
CHEMBL255708
CHEMBL486005 CHEMBL1616444 |
C005963
|
3 / 0 / 0 | 6 / 0 |
|
|
C00001849
|
Emetine
|
CHEMBL50588
CHEMBL192858 CHEMBL1090755 CHEMBL1325269 CHEMBL1435868 CHEMBL1515885 CHEMBL1624688 |
D004640
|
117 / 70 / 80 | 13 / 4 |
|
|
C00001907
|
Psychotrine
|
CHEMBL463445
|
|
|||
|
C00026848
|
Deoxytubulosine
/ 8'-Deoxytubulosine |
|
||||
|
C00027245
|
10-O-Demethylcephaeline
/ (-)-10-Demethylcephaeline |
|
||||
|
C00027384
|
Isocephaeline
|
CHEMBL255708
CHEMBL486005 CHEMBL1616444 |
3 / 0 / 0 |
|
||
|
C00027397
|
Isotubulosine
|
CHEMBL518568
CHEMBL535307 CHEMBL1254284 CHEMBL1369261 |
19 / 18 / 10 |
|
||
|
C00027421
|
Neocephaeline
/ (-)-Neocephaeline |
|
||||
|
C00027580
|
O-Methyltubulosine
|
C009778
|
|
|||
|
C00028167
|
Deoxydesmethyltubulosine
|
|
||||
|
C00038322
|
7'-O-Demethylcephaeline
|
CHEMBL519546
|
2 / 0 / 0 |
|
||
|
C00044486
|
7'-O-Demethylisocephaeline
/ (-)-7'-O-Demethylisocephaeline |
CHEMBL519546
|
2 / 0 / 0 |
|
||
|
C00044848
|
Klugine
/ (-)-Klugine |
CHEMBL486004
|
3 / 0 / 0 |
|
Human Protein / Gene in interactions
126 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001778 C00001835 C00001849 C00027384 C00027397 C00038322 C00044486 C00044848 | 0 / 0 |
| P27540 | Aryl hydrocarbon receptor nuclear translocator | Unclassified protein | C00001835 C00001849 C00027384 C00038322 C00044486 C00044848 | 0 / 0 |
| P20701 | Integrin alpha-L | Membrane receptor | C00001835 C00001849 C00027384 C00044848 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001778 C00001849 C00027397 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001778 C00001849 C00027397 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001778 C00001849 C00027397 | 4 / 1 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00001778 C00001849 C00027397 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00001778 C00001849 C00027397 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001778 C00001849 C00027397 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001778 C00001849 C00027397 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001778 C00001849 C00027397 | 0 / 1 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001778 C00001849 C00027397 | 1 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001778 C00027397 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00001778 C00027397 | 1 / 0 |
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00001778 C00027397 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00001778 C00027397 | 7 / 3 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00001778 C00027397 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00001778 C00027397 | 2 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00001778 C00027397 | 0 / 0 |
| P23467 | Receptor-type tyrosine-protein phosphatase beta | Receptor tyrosine-protein phosphatase | C00001778 C00027397 | 0 / 0 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00001778 C00027397 | 1 / 2 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00001849 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00001849 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00001849 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00001849 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00001849 | 1 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00001849 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00001849 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00001849 | 0 / 0 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001849 | 1 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00001849 | 1 / 8 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001849 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001849 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00001849 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00001849 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00001849 | 0 / 0 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 1 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00001849 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00001849 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00001849 | 1 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001849 | 0 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00001849 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00001849 | 1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001849 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00001849 | 1 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00001849 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001849 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00001849 | 1 / 1 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001849 | 11 / 10 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00001849 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00001849 | 0 / 0 |
| O75884 | Putative hydrolase RBBP9 | Enzyme | C00001849 | 0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001849 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00001849 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00001849 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00001849 | 1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001849 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00001849 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001849 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00001849 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00001849 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00001849 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00001849 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00001849 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001849 | 1 / 0 |
| P03956 | Interstitial collagenase | M10A | C00001849 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00001849 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00001849 | 2 / 2 |
| P42226 | Signal transducer and activator of transcription 6 | Unclassified protein | C00001849 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00001849 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00001849 | 2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00001849 | 0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00001849 | 0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001849 | 2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001849 | 5 / 9 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00001849 | 1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00001849 | 0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00001849 | 0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00001849 | 3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001849 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00001849 | 0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00001849 | 1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001849 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00001849 | 2 / 1 |
| P17252 | Protein kinase C alpha type | Alpha | C00001849 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00001849 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00001849 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001849 | 0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00001849 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00001849 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00001849 | 1 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00001849 | 0 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001849 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001849 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001849 | 0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00001849 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00001849 | 0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00001849 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00001849 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001849 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001849 | 0 / 0 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001849 | 0 / 0 |
| P08246 | Neutrophil elastase | S1A | C00001849 | 2 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001849 | 0 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001849 | 2 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00001849 | 4 / 3 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001849 | 0 / 3 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00001849 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00001849 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00001849 | 0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00001849 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00001849 | 0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00001849 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00001849 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001849 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001849 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00001849 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00001849 | 1 / 2 |
| O76082 | Solute carrier family 22 member 5 | Unclassified protein | C00001849 | 1 / 2 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00001849 | 7 / 37 |
| P42345 | Serine/threonine-protein kinase mTOR | Enzyme | C00001849 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001849 | 1 / 0 |
13 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00001835
C00001849
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00001835
C00001849
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00001835
C00001849
|
| 3570 | IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80 | interleukin 6 receptor |
C00001835
C00001849
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001835
C00001849
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001835
C00001849
|
| 10142 | AKAP9, AKAP-9, AKAP350, AKAP450, CG-NAP, HYPERION, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO | A kinase (PRKA) anchor protein 9 |
C00001849
|
| 4076 | CAPRIN1, GPIAP1, GPIP137, M11S1, RNG105, p137GPI | cell cycle associated protein 1 |
C00001849
|
| 55749 | CCAR1, RP11-437A18.1 | cell division cycle and apoptosis regulator 1 |
C00001849
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00001849
|
| 1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00001849
|
| 4137 | MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU | microtubule-associated protein tau |
C00001849
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001849
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (80)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #212140 | Carnitine deficiency, systemic primary; cdsp |
O76082
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 |
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (84)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00286 | Crohn's disease |
O76082
(related)
|
| H00525 | Disorders of fatty-acid oxidation |
O76082
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
Q06710 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|