Alangium lamarckii

• Index
• Plant Species
• Metabolite list (33)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Alangium lamarckii
Genus	Alangium
Family	Cornaceae / Aucubaceae / Garryaceae / Helwingiaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Alangium
Linked NCBI taxonomy ID	16896
Linked level	genus

Family

Family in NCBI taxonomy	Cornaceae
ID	42219

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (33)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00010604	Loganic acid	CHEMBL1081585 CHEMBL1079678 CHEMBL1356464 CHEMBL1452775	C002947	6 / 8 / 7		No. 64	No. 36
C00037307	Iridoid glycoside / (-)-Iridoid glycoside					No. 64	No. 36
C00037800	Secologanoside					No. 100	No. 36
C00032760	(-)-Benzyl beta-primeveroside / Benzyl alcohol beta-D-xylopyranosyl (1->6)-beta-D-glucopyranoside	CHEMBL1371061	C069904	3 / 1 / 1		No. 128	No. 72
C00036637	6'-O-alpha-D-glucopyranosylloganic acid					No. 222
C00001835	Cephaeline	CHEMBL255708 CHEMBL486005 CHEMBL1616444	C005963	3 / 0 / 0	6 / 0	No. 510	No. 4
C00027421	Neocephaeline / (-)-Neocephaeline					No. 510	No. 4
C00001796	Alangimarckine					No. 510	No. 4
C00001907	Psychotrine	CHEMBL463445				No. 510	No. 4
C00001795	Alangicine					No. 510	No. 4
C00027397	Isotubulosine	CHEMBL518568 CHEMBL535307 CHEMBL1254284 CHEMBL1369261		19 / 18 / 10		No. 510	No. 4
C00026848	Deoxytubulosine / 8'-Deoxytubulosine					No. 510	No. 4
C00027245	10-O-Demethylcephaeline / (-)-10-Demethylcephaeline					No. 510	No. 4
C00027384	Isocephaeline	CHEMBL255708 CHEMBL486005 CHEMBL1616444		3 / 0 / 0		No. 510	No. 4
C00001778	Tubulosine / (-)-Tubulosine	CHEMBL518568 CHEMBL535307 CHEMBL1254284 CHEMBL1369261	C009805	19 / 18 / 10		No. 510	No. 4
C00027550	Isoalangiside	CHEMBL486383 CHEMBL2138751		2 / 0 / 0		No. 577	No. 4
C00027567	Neoalangiside					No. 577	No. 4
C00001798	Alangiside	CHEMBL486383 CHEMBL2138751		2 / 0 / 0		No. 577	No. 4
C00027578	O-Methylisoalangiside					No. 577	No. 4
C00010794	Sweroside	CHEMBL456137	C049412	1 / 0 / 0		No. 806	No. 36
C00027252	3'-O-beta-D-glucopyranosylalangiside / (-)-3'-O-beta-D-glucopyranosylalangiside					No. 1411
C00027254	6'-alpha-D-glucopyranosylalangiside / (-)-6'-alpha-D-glucopyranosylalangiside					No. 1411
C00027255	6'-O-alpha-D-Xylopyranosylalangiside / (-)-6'-O-alpha-D-Xylopyranosylalangiside					No. 1411
C00027256	6'-O-beta-D-glucopyranosylalangiside / (-)-6'-O-beta-D-glucopyranosylalangiside					No. 1411
C00001805	Ankorine					No. 2276	No. 4
C00027270	Alangine / (-)-Alangine					No. 2276	No. 4
C00027473	Protoemetinol					No. 2276	No. 4
C00027472	Protoemetine					No. 2276	No. 4
C00027481	Salsoline / (-)-O7-Methylsalsolinol	CHEMBL1187592 CHEMBL1192723 CHEMBL1532461	C032837	3 / 4 / 3		No. 2962	No. 4
C00001794	Alamarine					No. 2972
C00001797	Alangimarine					No. 2972
C00027509	2'-O-trans-Sinapoylalangiside					No. 5314
C00027508	2'-O-trans-Feruloylalangiside / (-)-2'-O-trans-Feruloylalangiside					No. 5314

Human Protein / Gene in interactions

29 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00001778 C00001798 C00027397 C00027550 C00032760	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00001778 C00001835 C00027384 C00027397	0 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001778 C00001798 C00027397 C00027550	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001778 C00027397 C00027481	1 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001778 C00010604 C00027397	1 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001778 C00010604 C00027397	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001778 C00010604 C00027397	2 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00001778 C00027397	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00001778 C00027397	4 / 1
P20701	Integrin alpha-L	Membrane receptor	C00001835 C00027384	0 / 0
Q9H0H5	Rac GTPase-activating protein 1	Unclassified protein	C00001778 C00027397	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001778 C00027397	7 / 3
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001778 C00027397	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001778 C00027397	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001778 C00027397	1 / 1
P27540	Aryl hydrocarbon receptor nuclear translocator	Unclassified protein	C00001835 C00027384	0 / 0
P23467	Receptor-type tyrosine-protein phosphatase beta	Receptor tyrosine-protein phosphatase	C00001778 C00027397	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001778 C00027397	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001778 C00027397	0 / 1
O75164	Lysine-specific demethylase 4A	Enzyme	C00001778 C00027397	0 / 0
Q06710	Paired box protein Pax-8	Unclassified protein	C00001778 C00027397	1 / 2
P10636	Microtubule-associated protein tau	Unclassified protein	C00010604	4 / 3
P07900	Heat shock protein HSP 90-alpha	Other cytosolic protein	C00010794	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00032760	0 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00027481	0 / 0
P60033	CD81 antigen	Unclassified protein	C00010604	1 / 1
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00010604	0 / 3
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00032760	1 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00027481	3 / 3

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
6347	CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF	chemokine (C-C motif) ligand 2	C00001835
6351	CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4	chemokine (C-C motif) ligand 4	C00001835
6352	CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP	chemokine (C-C motif) ligand 5	C00001835
3570	IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80	interleukin 6 receptor	C00001835
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00001835
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00001835

Related Diseases

Diseases related to proteins in ChEMBL interactions