PCIDB

KNApSAcK Metabolite C00002075

Metabolite

KNApSAcK Entry

id C00002075
Name Swainsonine / (-)-Swainsonine
CAS RN 72741-87-8
Standard InChI InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2/t5-,6-,7+,8+/m1/s1
Standard InChI (Main Layer) InChI=1S/C8H15NO3/c10-5-2-1-3-9-4-6(11)8(12)7(5)9/h5-8,10-12H,1-4H2

Cluster

Phytochemical cluster No. 2
KCF-S cluster No. 677

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL63139 CHEMBL292716 CHEMBL302300 CHEMBL65098 CHEMBL371197

KEGG

By LinkDB C10173

CTD

By CAS RN D017026

Human Protein / Gene in interaction

4 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P43403 Tyrosine-protein kinase ZAP-70 Syk CHEMBL371197 CHEMBL981911 (1) CHEMBL981919 (1)
1 / 2
O43561 Linker for activation of T-cells family member 1 Unclassified protein CHEMBL371197 CHEMBL970294 (1) CHEMBL968354 (1)
0 / 0
P06239 Tyrosine-protein kinase Lck Src CHEMBL371197 CHEMBL981915 (1) CHEMBL981916 (1)
CHEMBL981917 (1) CHEMBL981918 (1)
0 / 1
O00754 Lysosomal alpha-mannosidase Enzyme CHEMBL371197 CHEMBL987286 (1) CHEMBL987287 (1)
CHEMBL987288 (1)
1 / 2

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#248500 Mannosidosis, alpha b, lysosomal; mansa O00754
#269840 Selective t-cell defect; stcd P43403

KEGG DISEASE (4)

KEGG disease name UniProt
H00139 alpha-Mannosidosis O00754 (related)
H00422 Glycoproteinoses O00754 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
P43403 (related)
H00005 Chronic lymphocytic leukemia (CLL) P43403 (marker)