KNApSAcK Metabolite C00002105
Metabolite
KNApSAcK Entry
| id | C00002105 |
|---|---|
| Name | Petasitenine |
| CAS RN | 60102-37-6 |
| Standard InChI | InChI=1S/C19H27NO7/c1-11-9-19(12(2)27-19)17(23)26-14-6-8-20(4)7-5-13(15(14)21)10-25-16(22)18(11,3)24/h5,11-12,14,24H,6-10H2,1-4H3/b13-5-/t11-,12-,14-,18-,19-/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C19H27NO7/c1-11-9-19(12(2)27-19)17(23)26-14-6-8-20(4)7-5-13(15(14)21)10-25-16(22)18(11,3)24/h5,11-12,14,24H,6-10H2,1-4H3 |
Cluster
| Phytochemical cluster | No. 2 |
|---|---|
| KCF-S cluster | No. 838 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL511627 CHEMBL1512570 CHEMBL1992587 |
KEGG
| By LinkDB | C10359 |
|---|
CTD
| By CAS RN | C014738 |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| asterids | 4 |
Family
| family name | count |
|---|---|
| Asteraceae | 4 |
List (4)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Petasites hybridus | 278673 | Asteraceae | asterids | Viridiplantae |
| Petasites japonicus | 186965 | Asteraceae | asterids | Viridiplantae |
| Pittocaulon bombycophole | 98711 | Asteraceae | asterids | Viridiplantae |
| Pittocaulon hintonii | 98711 | Asteraceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
3 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL1512570 |
CHEMBL1614108
(1)
CHEMBL1613886
(1)
|
0 / 1 |
| O00255 | Menin | Unclassified protein | CHEMBL1512570 |
CHEMBL1614531
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL1512570 |
CHEMBL1614531
(1)
|
1 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (3)
| OMIM | preferred title | UniProt |
|---|---|---|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
KEGG DISEASE (8)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|