KNApSAcK Metabolite C00025662
Metabolite
KNApSAcK Entry
| id | C00025662 |
|---|---|
| Name | (+)-Limacine / (+)-Fangchinoline |
| CAS RN | 436-77-1 |
| Standard InChI | InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3 |
Cluster
| Phytochemical cluster | No. 4 |
|---|---|
| KCF-S cluster | No. 10 |
Link
ChEMBL
| By standard InChI | CHEMBL504256 |
|---|---|
| By standard InChI Main Layer | CHEMBL504256 CHEMBL509803 CHEMBL500614 |
KEGG
| By LinkDB |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| eudicotyledons | 3 |
Family
| family name | count |
|---|---|
| Menispermaceae | 3 |
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Pachygone dasycarpa Kurz | 152360 | Menispermaceae | eudicotyledons | Viridiplantae |
| Stephania hernandifolia (Willd.)Walp. | 152366 | Menispermaceae | eudicotyledons | Viridiplantae |
| Stephania tetrandra S.Moore | 425106 | Menispermaceae | eudicotyledons | Viridiplantae |
Human Protein / Gene in interaction
12 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL504256 |
CHEMBL2114784
(1)
|
1 / 1 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | CHEMBL504256 |
CHEMBL1614076
(1)
|
1 / 1 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL504256 |
CHEMBL1738166
(1)
CHEMBL1794335
(1)
|
0 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | CHEMBL504256 |
CHEMBL2077437
(1)
|
1 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL504256 |
CHEMBL1008496
(1)
|
0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | CHEMBL504256 |
CHEMBL1794486
(1)
|
0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | CHEMBL504256 |
CHEMBL1794584
(1)
|
2 / 0 |
| O75496 | Geminin | Unclassified protein | CHEMBL504256 |
CHEMBL2114843
(1)
CHEMBL2114780
(1)
|
0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | CHEMBL504256 |
CHEMBL2114788
(1)
|
0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | CHEMBL504256 |
CHEMBL1737991
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL504256 |
CHEMBL2354311
(1)
|
1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | CHEMBL504256 |
CHEMBL1963966
(1)
|
0 / 0 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|