KNApSAcK Metabolite C00002596
Metabolite
KNApSAcK Entry
| id | C00002596 |
|---|---|
| Name | Deoxygomisin A |
| CAS RN | 82467-52-5 |
| Standard InChI | InChI=1S/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3/t12-,13+/m1/s1 |
| Standard InChI (Main Layer) | InChI=1S/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3 |
Cluster
| Phytochemical cluster | No. 21 |
|---|---|
| KCF-S cluster | No. 105 |
Link
ChEMBL
| By standard InChI | CHEMBL402435 |
|---|---|
| By standard InChI Main Layer | CHEMBL402435 CHEMBL479488 CHEMBL513752 |
KEGG
| By LinkDB | C10555 |
|---|
CTD
| By CAS RN |
|---|
Species
Summary
Plant class
| class name | count |
|---|---|
| Magnoliophyta | 1 |
Family
| family name | count |
|---|---|
| Schisandraceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Schisandra chinensis | 50507 | Schisandraceae | Magnoliophyta | Viridiplantae |
Human Protein / Gene in interaction
6 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P33527 | Multidrug resistance-associated protein 1 | drugs | CHEMBL479488 |
CHEMBL2077105
(1)
CHEMBL2077106
(1)
CHEMBL2077107 (1) CHEMBL2077108 (1) CHEMBL2077109 (1) CHEMBL2077838 (1) |
0 / 0 |
| P78527 | DNA-dependent protein kinase catalytic subunit | Atypical serine/threonine protein kinase PIKK subfamily | CHEMBL479488 |
CHEMBL1767683
(1)
|
0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | CHEMBL479488 |
CHEMBL1767682
(1)
|
1 / 4 |
| Q13535 | Serine/threonine-protein kinase ATR | Atypical serine/threonine protein kinase PIKK subfamily | CHEMBL479488 |
CHEMBL1767585
(1)
CHEMBL2183413
(1)
|
2 / 2 |
| O00255 | Menin | Unclassified protein | CHEMBL479488 |
CHEMBL1614257
(1)
|
2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | CHEMBL479488 |
CHEMBL1614257
(1)
|
1 / 3 |
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (6)
| OMIM | preferred title | UniProt |
|---|---|---|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #614564 | Cutaneous telangiectasia and cancer syndrome, familial; fctcs |
Q13535
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #210600 | Seckel syndrome 1; sckl1 |
Q13535
|
KEGG DISEASE (13)
| KEGG | disease name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00037 | Alveolar rhabdomyosarcoma |
Q13535
(related)
|
| H00992 | Seckel syndrome |
Q13535
(related)
|