PCIDB

KNApSAcK Metabolite C00048682

Metabolite

KNApSAcK Entry

id C00048682
Name Damnacanthal
CAS RN 477-84-9
Standard InChI InChI=1S/C16H10O5/c1-21-16-11(7-17)12(18)6-10-13(16)15(20)9-5-3-2-4-8(9)14(10)19/h2-7,18H,1H3
Standard InChI (Main Layer) InChI=1S/C16H10O5/c1-21-16-11(7-17)12(18)6-10-13(16)15(20)9-5-3-2-4-8(9)14(10)19/h2-7,18H,1H3

Cluster

Phytochemical cluster No. 62
KCF-S cluster No. 41

Link

ChEMBL

By standard InChI CHEMBL212948
By standard InChI Main Layer CHEMBL212948

KEGG

By LinkDB

CTD

By CAS RN C079170

Species

Summary

Plant class

class name count
asterids 2

Family

family name count
Rubiaceae 2

List (2)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Damnacanthus major 1277858 Rubiaceae asterids Viridiplantae
Saprosma fragrans 358842 Rubiaceae asterids Viridiplantae

Human Protein / Gene in interaction

10 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL212948 CHEMBL1794499 (2)
2 / 0
P10828 Thyroid hormone receptor beta NR1A2 CHEMBL212948 CHEMBL1613776 (1)
3 / 1
P11473 Vitamin D3 receptor NR1I1 CHEMBL212948 CHEMBL1794311 (2)
2 / 3
P00352 Retinal dehydrogenase 1 Enzyme CHEMBL212948 CHEMBL1614458 (2)
0 / 0
Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Enzyme CHEMBL212948 CHEMBL1115234 (1)
0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme CHEMBL212948 CHEMBL1738606 (1)
0 / 0
P06280 Alpha-galactosidase A Enzyme CHEMBL212948 CHEMBL1614217 (1)
1 / 1
P10636 Microtubule-associated protein tau Unclassified protein CHEMBL212948 CHEMBL1614250 (2) CHEMBL1614421 (2)
CHEMBL1614502 (1)
4 / 3
P06239 Tyrosine-protein kinase Lck Src CHEMBL212948 CHEMBL841200 (1) CHEMBL939225 (1)
CHEMBL939226 (1)
0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme CHEMBL212948 CHEMBL1738442 (2)
0 / 0

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (9)

KEGG disease name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)