Species

KNApSAcK Entry

Organism name Saprosma fragrans
Genus Saprosma
Family Rubiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Saprosma
Linked NCBI taxonomy ID 358842
Linked level genus

Family

Family in NCBI taxonomy Rubiaceae
ID 24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00048682 External link 512 Damnacanthal
CHEMBL212948
C079170
10 / 12 / 9 No. 41 No. 62

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P49798 Regulator of G-protein signaling 4 Unclassified protein C00048682 2 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00048682 3 / 1
P11473 Vitamin D3 receptor NR1I1 C00048682 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00048682 0 / 0
Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Enzyme C00048682 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00048682 0 / 0
P06280 Alpha-galactosidase A Enzyme C00048682 1 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00048682 4 / 3
P06239 Tyrosine-protein kinase Lck Src C00048682 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00048682 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (9)

KEGG name UniProt
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00125 Fabry disease P06280 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)