PCIDB

KNApSAcK Metabolite C00050143

Metabolite

KNApSAcK Entry

id C00050143
Name Lariciresinol acetate / (+)-Lariciresinol acetate
CAS RN 79114-77-5
Standard InChI InChI=1S/C22H26O7/c1-13(23)28-12-17-16(8-14-4-6-18(24)20(9-14)26-2)11-29-22(17)15-5-7-19(25)21(10-15)27-3/h4-7,9-10,16-17,22,24-25H,8,11-12H2,1-3H3/t16-,17-,22+/m0/s1
Standard InChI (Main Layer) InChI=1S/C22H26O7/c1-13(23)28-12-17-16(8-14-4-6-18(24)20(9-14)26-2)11-29-22(17)15-5-7-19(25)21(10-15)27-3/h4-7,9-10,16-17,22,24-25H,8,11-12H2,1-3H3

Cluster

Phytochemical cluster No. 21
KCF-S cluster No. 700

Link

ChEMBL

By standard InChI CHEMBL464991
By standard InChI Main Layer CHEMBL464991 CHEMBL1406708

KEGG

By LinkDB

CTD

By CAS RN

Species

Summary

Plant class

class name count
rosids 1

Family

family name count
Meliaceae 1

List (1)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aglaia spp. 201006 Meliaceae rosids Viridiplantae

Human Protein / Gene in interaction

18 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein CHEMBL1406708 CHEMBL1738312 (1)
0 / 0
P14618 Pyruvate kinase PKM Enzyme CHEMBL1406708 CHEMBL1613996 (1) CHEMBL1614428 (1)
0 / 0
P06746 DNA polymerase beta Enzyme CHEMBL1406708 CHEMBL1614079 (1)
0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase CHEMBL1406708 CHEMBL1614076 (1)
1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme CHEMBL1406708 CHEMBL1794585 (1)
0 / 0
P54132 Bloom syndrome protein Enzyme CHEMBL1406708 CHEMBL1614067 (1)
1 / 2
P39748 Flap endonuclease 1 Enzyme CHEMBL1406708 CHEMBL1794486 (1)
0 / 0
Q9Y253 DNA polymerase eta Enzyme CHEMBL1406708 CHEMBL1794569 (1)
1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein CHEMBL1406708 CHEMBL1794401 (1)
0 / 0
Q9UNA4 DNA polymerase iota Enzyme CHEMBL1406708 CHEMBL1794483 (1)
0 / 0
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1406708 CHEMBL1737991 (1)
0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme CHEMBL1406708 CHEMBL1614466 (1) CHEMBL1614211 (1)
0 / 0
Q9UBT6 DNA polymerase kappa Enzyme CHEMBL1406708 CHEMBL1794536 (1)
0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme CHEMBL1406708 CHEMBL1613829 (1)
0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein CHEMBL1406708 CHEMBL1613933 (1)
0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein CHEMBL1406708 CHEMBL1613933 (1)
1 / 6
O94925 Glutaminase kidney isoform, mitochondrial Enzyme CHEMBL1406708 CHEMBL2114738 (1)
0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1406708 CHEMBL2114796 (1)
2 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc Q14191
#232300 Glycogen storage disease ii P10253
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (8)

KEGG disease name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)