Species

KNApSAcK Entry

Organism name Aglaia spp.
Genus Aglaia
Family Meliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aglaia
Linked NCBI taxonomy ID 201006
Linked level genus

Family

Family in NCBI taxonomy Meliaceae
ID 43707

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00050183 External link 512 Pannellin
/ (-)-Pannellin
CHEMBL464992
CHEMBL571681
No. 449
C00049949 External link 512 3'-Methoxypannellin
/ (-)-3'-Methoxypannellin
No. 449
C00050184 External link 512 Pannellin 1-O-acetate
/ (-)-Pannellin 1-O-acetate
CHEMBL513962
No. 449
C00050143 External link 512 Lariciresinol acetate
/ (+)-Lariciresinol acetate
CHEMBL464991
CHEMBL1406708
18 / 6 / 8 No. 700 No. 21
C00050197 External link 512 Piriferinol
/ (+)-Piriferinol
CHEMBL448832
No. 1008
C00041323 External link 512 Aglalactone
No. 1311
C00050087 External link 512 Edulimide
CHEMBL464783
No. 6595

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00050143 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00050143 0 / 0
P06746 DNA polymerase beta Enzyme C00050143 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00050143 1 / 1
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00050143 0 / 0
P54132 Bloom syndrome protein Enzyme C00050143 1 / 2
P39748 Flap endonuclease 1 Enzyme C00050143 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00050143 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00050143 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00050143 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00050143 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00050143 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00050143 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00050143 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00050143 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00050143 1 / 4
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00050143 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00050143 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc Q14191
#232300 Glycogen storage disease ii P10253
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (8)

KEGG name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)