| class name | count |
|---|
| class name | count |
|---|---|
| Streptomycetaceae | 3 |
| Thermomonosporaceae | 2 |
| Pseudonocardiaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00014944
|
Chandrananimycin A
|
CHEMBL2322651
|
1 / 0 / 0 |
|
||
|
C00014945
|
Chandrananimycin B
|
|
||||
|
C00016208
|
4-Demethoxymichigazone
|
|
||||
|
C00017063
|
Exfoliazone
/ Antibiotic BT 38 |
CHEMBL2311997
|
C067081
|
1 / 0 / 0 |
|
|
|
C00018683
|
NSC 94945
/ AV Toxin C / Questiomycin A / 2-Aminophenoxazone / 2-Amino-3-phenoxazone / Acrospermum viticola toxin C |
CHEMBL146710
|
C005512
|
32 / 18 / 20 |
|
|
|
C00027921
|
BE-39907B
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00014944 C00017063 C00018683 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00018683 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00018683 | 0 / 0 |
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00018683 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00018683 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00018683 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00018683 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00018683 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00018683 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00018683 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00018683 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00018683 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00018683 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00018683 | 1 / 1 |
| P09923 | Intestinal-type alkaline phosphatase | Enzyme | C00018683 | 0 / 0 |
| P05186 | Alkaline phosphatase, tissue-nonspecific isozyme | Enzyme | C00018683 | 3 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00018683 | 1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00018683 | 1 / 2 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00018683 | 0 / 0 |
| P10696 | Alkaline phosphatase, placental-like | Enzyme | C00018683 | 0 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00018683 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00018683 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00018683 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00018683 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00018683 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00018683 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00018683 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00018683 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00018683 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00018683 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00018683 | 2 / 5 |
| P01215 | Glycoprotein hormones alpha chain | Unclassified protein | C00018683 | 0 / 3 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #146300 | Hypophosphatasia, adult |
P05186
|
| #241510 | Hypophosphatasia, childhood |
P05186
|
| #241500 | Hypophosphatasia, infantile |
P05186
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00081 | Hashimoto's thyroiditis |
P01215
(marker)
|
| H00082 | Graves' disease |
P01215
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P01215
(marker)
|
| H00213 | Hypophosphatasia |
P05186
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00023 | Testicular cancer |
P10696
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|