Plant Species


Cumulative plant class count

class name count
asterids 93

Cumulative family count

class name count
Rubiaceae 83
Apocynaceae 10

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (37)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001703 External link 512 Carapanaubine
C00001752 External link 512 Mitraphylline
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00001764 External link 512 Rhynchophylline
CHEMBL519266
CHEMBL480521
CHEMBL1909423
CHEMBL1909424
C052714
2 / 2 / 2
C00025147 External link 512 3-Isorauniticine pseudoindoxyl
C00025151 External link 512 Akuammigine pseudoindoxyl
C00025158 External link 512 Ciliaphylline
C00025162 External link 512 Corynoxeine
CHEMBL481358
CHEMBL481359
C054799
C00025163 External link 512 Corynoxine
CHEMBL519266
CHEMBL480521
CHEMBL1909423
CHEMBL1909424
2 / 2 / 2
C00025164 External link 512 Corynoxine B
CHEMBL519266
CHEMBL480521
CHEMBL1909423
CHEMBL1909424
2 / 2 / 2
C00025180 External link 512 Isomitrafoline
C00025181 External link 512 Isomitraphylline
/ Ajmalicine oxindole A
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00025184 External link 512 Isorhynchophylline
/ (+/-)-Isorhynchophylline
CHEMBL519266
CHEMBL480521
CHEMBL1909423
CHEMBL1909424
2 / 2 / 2
C00025185 External link 512 Javaphylline
C00025188 External link 512 Mitragynol
/ Mitrafoline
C00025189 External link 512 Mitragynine oxindole A
C00025190 External link 512 Mitragynine oxindole B
C00025203 External link 512 Rauniticine oxindole A
/ Rauniticine-allo-oxindole A
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00025204 External link 512 Rauniticine pseudoindoxyl
C00025208 External link 512 Rhynchociline
/ Rhynchocilin
C00025210 External link 512 Speciofoline
C00025212 External link 512 Specionoxeine
C00025217 External link 512 Uncarine A
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
C019589
8 / 14 / 9
C00025218 External link 512 Uncarine B
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00025219 External link 512 Uncarine C
/ allo-Pteropodine
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00025220 External link 512 Uncarin D
/ Uncarine D
/ Speciophylline
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
C104393
8 / 14 / 9
C00025221 External link 512 Uncarine E
/ 7-Isopteropodine
/ allo-Isopteropodine
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00025222 External link 512 Uncarine F
/ Speciofiline
CHEMBL562222
CHEMBL1449034
CHEMBL1886339
CHEMBL2135897
CHEMBL2307077
CHEMBL2355088
8 / 14 / 9
C00030536 External link 512 Isomitraphylline N-oxide
C00030537 External link 512 Isomitraphyllinol
C00031895 External link 512 Isocorynoxeine
CHEMBL481358
CHEMBL481359
C00031913 External link 512 Isospecionoxeine
C00034996 External link 512 16,17-Dihydro-17beta-hydroxymitraphylline
C00038175 External link 512 18,19-Dehydrocorynoxinic acid
/ (+)-18,19-Dehydrocorynoxinic acid
CHEMBL481352
CHEMBL521425
C00038176 External link 512 18,19-Dehydrocorynoxinic acid B
/ (-)-18,19-Dehydrocorynoxinic acid B
CHEMBL481352
CHEMBL521425
C00049185 External link 512 Isomajdine
CHEMBL2333535
C00049218 External link 512 Majdine
CHEMBL2333535
C00049285 External link 512 Rauvoxinine

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P83916 Chromobox protein homolog 1 Unclassified protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 1 / 1
P37840 Alpha-synuclein Unclassified protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 4 / 2
P11308 Transcriptional regulator ERG Unclassified protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 7 / 3
O75496 Geminin Unclassified protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 0 / 0
P42858 Huntingtin Unclassified protein C00001752 C00025181 C00025203 C00025217 C00025218 C00025219 C00025220 C00025221 C00025222 1 / 1
P16389 Potassium voltage-gated channel subfamily A member 2 KCNA, Kv1.x (Shaker) C00001764 C00025163 C00025164 C00025184 0 / 0
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00001764 C00025163 C00025164 C00025184 2 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#127750 Dementia, lewy body; dlb P37840
#612219 Ewing sarcoma; es P11308
#232300 Glycogen storage disease ii P10253
#143100 Huntington disease; hd P42858
#613688 Long qt syndrome 2; lqt2 Q12809
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#609620 Short qt syndrome 1; sqt1 Q12809

KEGG DISEASE (11)

KEGG name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)