| Organism name | Primula veris |
|---|---|
| Genus | Primula |
| Family | Primulaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Primula veris |
|---|---|
| Linked NCBI taxonomy ID | 170927 |
| Linked level | species |
| Family in NCBI taxonomy | Primulaceae |
|---|---|
| ID | 4335 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00005588
|
Isorhamnetin 3-rhamnosyl-(1->2)-[rhamnosyl-(1->6)-galactoside]-7-rhamnoside
|
No. 5 | No. 15 |
|
||||
|
C00005568
|
Isorhamnetin 3-rhamnosyl-(1->2)-[rhamnosyl-(1->6)-galactoside]
|
CHEMBL450526
|
No. 5 | No. 15 |
|
|||
|
C00003857
|
Zapotin
/ 5,6,2',6'-Tetramethoxyflavone / 2-(2,6-Dimethoxyphenyl)-5,6-dimethoxy-4H-1-benzopyran-4-one |
CHEMBL375582
|
1 / 0 / 0 | No. 8 | No. 15 |
|
||
|
C00035491
|
3'-Methoxy-4',5'-methylenedioxyflavone
|
No. 27 | No. 15 |
|
||||
|
C00013299
|
3',4',5'-Trimethoxyflavone
/ 2-(3,4,5-Trimethoxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL307856
|
16 / 7 / 3 | No. 35 | No. 15 |
|
||
|
C00035474
|
2',5'-Dimethoxyflavone
|
No. 35 | No. 15 |
|
||||
|
C00035490
|
3'-Hydroxy-4',5'-dimethoxyflavone
|
No. 35 | No. 15 |
|
||||
|
C00035488
|
3',4'-Dimethoxyflavone
|
CHEMBL91153
|
15 / 21 / 19 | No. 35 | No. 15 |
|
||
|
C00003791
|
2'-Hydroxyflavone
|
CHEMBL144278
|
C056011
|
No. 76 | No. 15 |
|
||
|
C00035482
|
2'-Methoxyflavone
|
CHEMBL147722
|
No. 76 | No. 15 |
|
|||
|
C00035492
|
3'-Methoxyflavone
|
CHEMBL342343
|
No. 76 | No. 15 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q16637 | Survival motor neuron protein | Unclassified protein | C00035488 | 4 / 1 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00035488 | 3 / 1 |
| P08183 | Multidrug resistance protein 1 | drug | C00035488 | 1 / 0 |
| P11926 | Ornithine decarboxylase | Lyase | C00003857 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00035488 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00035488 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00035488 | 0 / 0 |
| P06280 | Alpha-galactosidase A | Enzyme | C00035488 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00035488 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00035488 | 3 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00035488 | 2 / 2 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00035488 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00035488 | 4 / 3 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00013299 | 0 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00035488 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00035488 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00035488 | 1 / 2 |
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00013299 | 0 / 0 |
| P68366 | Tubulin alpha-4A chain | Structural | C00013299 | 0 / 0 |
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00013299 | 1 / 0 |
| P04350 | Tubulin beta-4A chain | Structural | C00013299 | 2 / 0 |
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00013299 | 0 / 0 |
| P07437 | Tubulin beta chain | Structural | C00013299 | 0 / 0 |
| Q71U36 | Tubulin alpha-1A chain | Structural | C00013299 | 1 / 1 |
| P68371 | Tubulin beta-4B chain | Structural | C00013299 | 0 / 0 |
| Q13509 | Tubulin beta-3 chain | Structural | C00013299 | 2 / 1 |
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00013299 | 0 / 0 |
| Q13885 | Tubulin beta-2A chain | Structural | C00013299 | 0 / 0 |
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00013299 | 0 / 0 |
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00013299 | 0 / 0 |
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00013299 | 0 / 0 |
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00013299 | 1 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 |
Q13509
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 |
P04350
|
| #301500 | Fabry disease |
P06280
|
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a |
Q13509
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 |
P04350
|
| #611603 | Lissencephaly 3; lis3 |
Q71U36
|
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related |
Q9H4B7
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa |
Q9BVA1
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00125 | Fabry disease |
P06280
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) |
Q13509
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00268 | Lissencephaly (LIS) |
Q71U36
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|