Organism name | Alvaradoa jamaicensis |
---|---|
Genus | Alvaradoa |
Family | Picramniaceae |
Kingdom | Plantae |
Linked NCBI taxonomy name | Alvaradoa |
---|---|
Linked NCBI taxonomy ID | 85160 |
Linked level | genus |
Family in NCBI taxonomy | Picramniaceae |
---|---|
ID | 85159 |
Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
---|---|
ID | 33090 |
Plant class | rosids |
---|---|
ID | 71275 |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00000568
![]() |
Chrysophanol
|
CHEMBL41092
|
C027113
|
20 / 17 / 20 | 1 / 0 | No. 41 | No. 62 |
![]() |
C00019420
![]() |
Physcion
/ 1,8-Dihydroxy-3-methyl-6-methoxyanthraquinone |
CHEMBL42624
|
C008905
|
18 / 20 / 14 | 1 / 0 | No. 41 | No. 62 |
![]() |
C00049106
![]() |
Alvaradoin B
/ (-)-Alvaradoin B |
CHEMBL455345
CHEMBL507834 |
No. 594 |
![]() |
||||
C00049105
![]() |
Alvaradoin A
/ (-)-Alvaradoin A |
CHEMBL455345
CHEMBL507834 |
No. 594 |
![]() |
||||
C00049107
![]() |
Alvaradoin C
/ (-)-Alvaradoin C |
CHEMBL455603
CHEMBL510048 |
No. 594 |
![]() |
||||
C00049108
![]() |
Alvaradoin D
/ (-)-Alvaradoin D |
CHEMBL455603
CHEMBL510048 |
No. 594 |
![]() |
accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P11473 | Vitamin D3 receptor | NR1I1 | C00000568 C00019420 | 2 / 3 |
B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000568 C00019420 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00000568 C00019420 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00000568 C00019420 | 4 / 3 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00000568 C00019420 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00000568 C00019420 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000568 | 0 / 0 |
P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00000568 | 4 / 2 |
P04150 | Glucocorticoid receptor | NR3C1 | C00000568 | 0 / 1 |
Q9H244 | P2Y purinoceptor 12 | Purine receptor | C00019420 | 1 / 1 |
P06280 | Alpha-galactosidase A | Enzyme | C00019420 | 1 / 1 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00000568 | 0 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00019420 | 2 / 2 |
P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00000568 | 0 / 0 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00019420 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000568 | 0 / 1 |
P08311 | Cathepsin G | S1A | C00019420 | 0 / 0 |
P08246 | Neutrophil elastase | S1A | C00019420 | 2 / 1 |
Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000568 | 0 / 0 |
O43451 | Maltase-glucoamylase, intestinal | Hydrolase | C00019420 | 0 / 0 |
P06239 | Tyrosine-protein kinase Lck | Src | C00019420 | 0 / 1 |
P16473 | Thyrotropin receptor | Glycohormone receptor | C00000568 | 3 / 2 |
O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00000568 | 0 / 0 |
P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000568 | 0 / 0 |
Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00000568 | 0 / 0 |
Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00000568 | 1 / 1 |
O00255 | Menin | Unclassified protein | C00000568 | 2 / 5 |
Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000568 | 1 / 2 |
Q92731 | Estrogen receptor beta | NR3A2 | C00019420 | 0 / 1 |
P03372 | Estrogen receptor | NR3A1 | C00019420 | 1 / 1 |
P09619 | Platelet-derived growth factor receptor beta | Pdgfr | C00019420 | 5 / 1 |
P16234 | Platelet-derived growth factor receptor alpha | Pdgfr | C00019420 | 2 / 1 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
581 | BAX, BCL2L4 | BCL2-associated X protein |
C00019420
|
196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00000568
|
OMIM | preferred title | UniProt |
---|---|---|
#615007 | Basal ganglia calcification, idiopathic, 4; ibgc4 |
P09619
|
#609821 | Bleeding disorder, platelet-type, 8; bdplt8 |
Q9H244
|
#114480 | Breast cancer |
P38398
|
#604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
#162800 | Cyclic neutropenia |
P08246
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#615363 | Estrogen resistance; estrr |
P03372
|
#301500 | Fabry disease |
P06280
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#606764 | Gastrointestinal stromal tumor; gist |
P16234
|
#605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
#607685 | Hypereosinophilic syndrome, idiopathic; hes |
P16234
|
#145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
#603373 | Hyperthyroidism, familial gestational |
P16473
|
#609152 | Hyperthyroidism, nonautoimmune |
P16473
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
#607785 | Juvenile myelomonocytic leukemia; jmml |
P09619
|
#601626 | Leukemia, acute myeloid; aml |
P09619
|
#131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#131440 | Myeloproliferative disorder, chronic, with eosinophilia |
P09619
|
#228550 | Myofibromatosis, infantile, 1; imf1 |
P09619
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#167000 | Ovarian cancer |
P38398
|
#614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG | name | UniProt |
---|---|---|
H00033 | Adrenal carcinoma |
O00255
(related)
|
H00034 | Carcinoid |
O00255
(related)
|
H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
H00246 | Primary hyperparathyroidism |
O00255
(related)
|
H01102 | Pituitary adenomas |
O00255
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
Q92731 (marker) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00125 | Fabry disease |
P06280
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00042 | Glioma |
P09619
(related)
P16234 (related) |
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
H01269 | Congenital hyperthyroidism |
P16473
(related)
|
H00027 | Ovarian cancer |
P38398
(related)
|
H00031 | Breast cancer |
P38398
(related)
|
H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
H01235 | Bleeding disorder platelet-type |
Q9H244
(related)
|
H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|