PCIDB

Piper sylvaticum Roxb.

Species

KNApSAcK Entry

Organism name Piper sylvaticum Roxb.
Genus Piper
Family Piperaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Piper sylvaticum
Linked NCBI taxonomy ID 405345
Linked level species

Family

Family in NCBI taxonomy Piperaceae
ID 16739

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003870 External link 512 Luteolin 7,3',4'-trimethyl ether
/ 5-Hydroxy-7,3',4'-trimethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
CHEMBL468876
No. 35 No. 15
C00003795 External link 512 Tectochrysin
/ 5-hydroxy-7-methoxyflavone
CHEMBL164841
12 / 19 / 14 No. 76 No. 15
C00037873 External link 512 Sylvatine
No. 638

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04062 Glucosylceramidase Enzyme C00003795 6 / 4
P37840 Alpha-synuclein Unclassified protein C00003795 4 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00003795 3 / 2
P08183 Multidrug resistance protein 1 drug C00003795 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003795 0 / 1
O75496 Geminin Unclassified protein C00003795 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00003795 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003795 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003795 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003795 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00003795 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003795 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#127750 Dementia, lewy body; dlb P37840
#609535 Drug metabolism, poor, cyp2c19-related P33261
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#257220 Niemann-pick disease, type c1; npc1 O15118
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P04062
P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (14)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
P37840 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00057 Parkinson's disease (PD) P37840 (related)