Species

KNApSAcK Entry

Organism name Aspergillus sp.
Genus Aspergillus
Family Trichocomaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aspergillus sp.
Linked NCBI taxonomy ID 5065
Linked level species

Family

Family in NCBI taxonomy Aspergillaceae
ID 1131492

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (31)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00039871 External link 512 Notoamide A
/ (-)-Notoamide A
No. 508
C00039877 External link 512 Notoamide H
/ (-)-Notoamide H
No. 508
C00040262 External link 512 Sclerotiamide
/ (-)-Sclerotiamide
CHEMBL511731
No. 508
C00039872 External link 512 Notoamide B
/ (-)-Notoamide B
CHEMBL2042022
No. 508
C00023629 External link 512 Nidurufin
No. 581 No. 62
C00015450 External link 512 UCT 1O72M1
/ UCT 1072M1
/ (-)-UCT 1072M1
No. 581 No. 62
C00015451 External link 512 UCT 1072M2
/ (-)-1,2,3,4,4a,13b-Hexahydro-3,9,11,13-tetrahydroxy-anthra[2,3-b]benzofuran-7,12-dione
No. 581 No. 62
C00015452 External link 512 UCT 1O72M3
/ UCT 1072M3
/ (3R,4aR,13bS)-rel-(+)-1,2,3,4,4a,13b-Hexahydro-3,9,11,13-tetrahydroxy-anthra[2,3-b]benzofuran-7,12-dione
No. 581 No. 62
C00000572 External link 512 Sulochrin
CHEMBL61133
C111298
12 / 5 / 6 No. 1795
C00026745 External link 512 Aspergillamide B
/ (-)-Aspergillamide B
No. 1864
C00026744 External link 512 Aspergillamide A
/ (-)-Aspergillamide A
No. 1864
C00011284 External link 512 Neoechinulin A
CHEMBL400768
No. 1942
C00038960 External link 512 Dehydroxychlorofusarielin B
/ (-)-Dehydroxychlorofusarielin B
CHEMBL426203
No. 2009
C00016442 External link 512 Fusarielin A
CHEMBL228444
No. 2009
C00016443 External link 512 Fusarielin B
CHEMBL228495
No. 2009
C00011277 External link 512 Deoxybrevianamide E
/ L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan anhydride
No. 2184
C00039875 External link 512 Notoamide F
/ (+)-Notoamide F
CHEMBL461207
No. 2525
C00039878 External link 512 Notoamide I
/ (+)-Notoamide I
CHEMBL518633
No. 2525
C00026831 External link 512 Stephacidin A
/ (+)-Stephacidin A
CHEMBL2042024
No. 2525
C00039876 External link 512 Notoamide G
/ (+)-Notoamide G
No. 2525
C00048582 External link 512 1-Deoxytetrahydrobostrycin
CHEMBL1224805
No. 3065
C00048875 External link 512 Tetrahydrobostrycin
/ (-)-Tetrahydrobostrycin
CHEMBL1224806
No. 3065
C00016150 External link 512 TAN 1415A
/ RES 1214-1
CHEMBL469424
C078941
34 / 17 / 16 No. 3263
C00045339 External link 512 Methyl asterrate
CHEMBL451989
No. 3263
C00011268 External link 512 LL-S490beta
/ LL-S 490beta
/ Acetylaszonalenin
CHEMBL480101
CHEMBL485042
1 / 0 / 0 No. 3596
C00039873 External link 512 Notoamide C
CHEMBL2332633
No. 3796
C00039874 External link 512 Notoamide D
/ (-)-Notoamide D
No. 3796
C00039880 External link 512 Notoamide K
/ (-)-Notoamide K
CHEMBL460140
No. 3796
C00039879 External link 512 Notoamide J
/ (-)-Notoamide J
CHEMBL460139
No. 3882
C00031830 External link 512 Golmaenone
/ (+)-Golmaenone
No. 7446
C00001554 External link 512 Tenuazonic acid
No. 8799

Human Protein / Gene in interactions

36 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UNA4 DNA polymerase iota Enzyme C00000572 C00016150 0 / 0
Q01196 Runt-related transcription factor 1 Unclassified protein C00000572 C00016150 1 / 4
Q13951 Core-binding factor subunit beta Unclassified protein C00000572 C00016150 0 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00000572 C00016150 0 / 0
P06746 DNA polymerase beta Enzyme C00000572 C00016150 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00000572 C00016150 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000572 C00016150 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00000572 C00016150 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00000572 C00016150 1 / 1
O75496 Geminin Unclassified protein C00000572 C00016150 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00000572 C00016150 2 / 0
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00016150 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00016150 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00016150 2 / 3
P83916 Chromobox protein homolog 1 Unclassified protein C00016150 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00016150 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00016150 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00011268 0 / 0
P39748 Flap endonuclease 1 Enzyme C00016150 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00016150 1 / 0
P54132 Bloom syndrome protein Enzyme C00016150 1 / 2
P10636 Microtubule-associated protein tau Unclassified protein C00016150 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00016150 0 / 0
Q07817 Bcl-2-like protein 1 Other cytosolic protein C00016150 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00000572 1 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00016150 0 / 0
P14618 Pyruvate kinase PKM Enzyme C00016150 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00016150 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00016150 1 / 0
Q99700 Ataxin-2 Unclassified protein C00016150 1 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00016150 0 / 0
Q9UBT2 SUMO-activating enzyme subunit 2 Enzyme C00016150 0 / 0
Q9UBE0 SUMO-activating enzyme subunit 1 Unclassified protein C00016150 0 / 0
P63165 Small ubiquitin-related modifier 1 Unclassified protein C00016150 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00016150 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00016150 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc P84022
Q14191
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#257220 Niemann-pick disease, type c1; npc1 O15118
#613705 Orofacial cleft 10; ofc10 P63165
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (17)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00516 Isolated orofacial clefts P63165 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)