| Organism name | Aspergillus sp. |
|---|---|
| Genus | Aspergillus |
| Family | Trichocomaceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Aspergillus sp. |
|---|---|
| Linked NCBI taxonomy ID | 5065 |
| Linked level | species |
| Family in NCBI taxonomy | Aspergillaceae |
|---|---|
| ID | 1131492 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00039871
|
Notoamide A
/ (-)-Notoamide A |
No. 508 |
|
|||||
|
C00039877
|
Notoamide H
/ (-)-Notoamide H |
No. 508 |
|
|||||
|
C00040262
|
Sclerotiamide
/ (-)-Sclerotiamide |
CHEMBL511731
|
No. 508 |
|
||||
|
C00039872
|
Notoamide B
/ (-)-Notoamide B |
CHEMBL2042022
|
No. 508 |
|
||||
|
C00023629
|
Nidurufin
|
No. 581 | No. 62 |
|
||||
|
C00015450
|
UCT 1O72M1
/ UCT 1072M1 / (-)-UCT 1072M1 |
No. 581 | No. 62 |
|
||||
|
C00015451
|
UCT 1072M2
/ (-)-1,2,3,4,4a,13b-Hexahydro-3,9,11,13-tetrahydroxy-anthra[2,3-b]benzofuran-7,12-dione |
No. 581 | No. 62 |
|
||||
|
C00015452
|
UCT 1O72M3
/ UCT 1072M3 / (3R,4aR,13bS)-rel-(+)-1,2,3,4,4a,13b-Hexahydro-3,9,11,13-tetrahydroxy-anthra[2,3-b]benzofuran-7,12-dione |
No. 581 | No. 62 |
|
||||
|
C00000572
|
Sulochrin
|
CHEMBL61133
|
C111298
|
12 / 5 / 6 | No. 1795 |
|
||
|
C00026745
|
Aspergillamide B
/ (-)-Aspergillamide B |
No. 1864 |
|
|||||
|
C00026744
|
Aspergillamide A
/ (-)-Aspergillamide A |
No. 1864 |
|
|||||
|
C00011284
|
Neoechinulin A
|
CHEMBL400768
|
No. 1942 |
|
||||
|
C00038960
|
Dehydroxychlorofusarielin B
/ (-)-Dehydroxychlorofusarielin B |
CHEMBL426203
|
No. 2009 |
|
||||
|
C00016442
|
Fusarielin A
|
CHEMBL228444
|
No. 2009 |
|
||||
|
C00016443
|
Fusarielin B
|
CHEMBL228495
|
No. 2009 |
|
||||
|
C00011277
|
Deoxybrevianamide E
/ L-Prolyl-2-(1,1-dimethylallyl)-L-tryptophan anhydride |
No. 2184 |
|
|||||
|
C00039875
|
Notoamide F
/ (+)-Notoamide F |
CHEMBL461207
|
No. 2525 |
|
||||
|
C00039878
|
Notoamide I
/ (+)-Notoamide I |
CHEMBL518633
|
No. 2525 |
|
||||
|
C00026831
|
Stephacidin A
/ (+)-Stephacidin A |
CHEMBL2042024
|
No. 2525 |
|
||||
|
C00039876
|
Notoamide G
/ (+)-Notoamide G |
No. 2525 |
|
|||||
|
C00048582
|
1-Deoxytetrahydrobostrycin
|
CHEMBL1224805
|
No. 3065 |
|
||||
|
C00048875
|
Tetrahydrobostrycin
/ (-)-Tetrahydrobostrycin |
CHEMBL1224806
|
No. 3065 |
|
||||
|
C00016150
|
TAN 1415A
/ RES 1214-1 |
CHEMBL469424
|
C078941
|
34 / 17 / 16 | No. 3263 |
|
||
|
C00045339
|
Methyl asterrate
|
CHEMBL451989
|
No. 3263 |
|
||||
|
C00011268
|
LL-S490beta
/ LL-S 490beta / Acetylaszonalenin |
CHEMBL480101
CHEMBL485042 |
1 / 0 / 0 | No. 3596 |
|
|||
|
C00039873
|
Notoamide C
|
CHEMBL2332633
|
No. 3796 |
|
||||
|
C00039874
|
Notoamide D
/ (-)-Notoamide D |
No. 3796 |
|
|||||
|
C00039880
|
Notoamide K
/ (-)-Notoamide K |
CHEMBL460140
|
No. 3796 |
|
||||
|
C00039879
|
Notoamide J
/ (-)-Notoamide J |
CHEMBL460139
|
No. 3882 |
|
||||
|
C00031830
|
Golmaenone
/ (+)-Golmaenone |
No. 7446 |
|
|||||
|
C00001554
|
Tenuazonic acid
|
No. 8799 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000572 C00016150 | 0 / 0 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00000572 C00016150 | 1 / 4 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00000572 C00016150 | 0 / 1 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00000572 C00016150 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00000572 C00016150 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00000572 C00016150 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00000572 C00016150 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00000572 C00016150 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00000572 C00016150 | 1 / 1 |
| O75496 | Geminin | Unclassified protein | C00000572 C00016150 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000572 C00016150 | 2 / 0 |
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00016150 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00016150 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00016150 | 2 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00016150 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00016150 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00016150 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00011268 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00016150 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00016150 | 1 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00016150 | 1 / 2 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00016150 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00016150 | 0 / 0 |
| Q07817 | Bcl-2-like protein 1 | Other cytosolic protein | C00016150 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00000572 | 1 / 1 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00016150 | 0 / 0 |
| P14618 | Pyruvate kinase PKM | Enzyme | C00016150 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00016150 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00016150 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00016150 | 1 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00016150 | 0 / 0 |
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00016150 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00016150 | 0 / 0 |
| P63165 | Small ubiquitin-related modifier 1 | Unclassified protein | C00016150 | 1 / 1 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00016150 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00016150 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #210900 | Bloom syndrome; blm |
P54132
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #613705 | Orofacial cleft 10; ofc10 |
P63165
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00516 | Isolated orofacial clefts |
P63165
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|