Species

KNApSAcK Entry

Organism name Platanus acerifolia
Genus Platanus
Family Platanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Platanus x acerifolia
Linked NCBI taxonomy ID 140101
Linked level species

Family

Family in NCBI taxonomy Platanaceae
ID 4401

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (23)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005150 External link 512 Kaempferol 7-rhamnoside
/ Kaempferol 7-O-rhamnoside
/ Kaempferol 7-O-alpha-L-rhamnopyranoside
CHEMBL1288270
CHEMBL1289337
No. 2 No. 15
C00005140 External link 512 Afzelin
/ Kaempferol 3-O-alpha-rhamnoside
/ Kaempferol 3-O-alpha-L-rhamnopyranoside
CHEMBL240528
CHEMBL515798
C477954
4 / 2 / 2 No. 2 No. 15
C00004554 External link 512 3-Hydroxywogonin
/ 8-Methoxygalangin
/ 8-Hydroxygalangin 8-methyl ether
/ 3,5,7-Trihydroxy-8-methoxyflavone
/ 3,5,7-Trihydroxy-8-methoxy-2-phenyl-4H-1-benzopyran-4-one
No. 3 No. 15
C00004011 External link 512 5,7-Dihydroxy-8-prenylflavone
CHEMBL166376
No. 15 No. 15
C00004993 External link 512 Licoflavonol
/ 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CHEMBL600185
No. 15 No. 15
C00005010 External link 512 Isolicoflavonol
/ 3,5,7-Trihydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]-4H-1-benzopyran-4-one
CHEMBL457679
5 / 5 / 3 No. 15 No. 15
C00004992 External link 512 Platanetin
No. 15 No. 15
C00008190 External link 512 7-O-Prenylcryptostrobin
No. 28 No. 14
C00008187 External link 512 6-C-Prenyl-8-C-methylpinocembrin
No. 28 No. 14
C00013770 External link 512 Kaempferol 3-(2''-(Z)-p-coumaroylrhamnoside)
/ (Z)-3-[[6-Deoxy-2-O-[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
No. 30 No. 15
C00005851 External link 512 Tiliroside
/ Potengriffioside A
/ Kaempferol 3-O-beta-D-(6''-coumaroyl)-glucopyranoside
CHEMBL266564
CHEMBL499705
C052083
2 / 1 / 2 No. 30 No. 15
C00005863 External link 512 Kaempferol 3-(2-(E)-p-coumarylrhamnoside)
/ 3-[[6-Deoxy-2-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
No. 30 No. 15
C00004878 External link 512 Pityrogrammin
No. 67 No. 15
C00004875 External link 512 Platanin
No. 67 No. 15
C00004880 External link 512 Isoplatanin
No. 67 No. 15
C00005867 External link 512 Platanoside
/ Kaempferol 3-(2'',3''-di-(E)-p-coumaroylrhamnoside)
/ 3-[[6-Deoxy-2,3-bis-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-alpha-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
CHEMBL1075910
CHEMBL1075911
CHEMBL1080027
No. 231
C00004990 External link 512 8-(1,1-Dimethylallyl)galangin
/ 3,5,7-Trihydroxy-8-(1,1-dimethylprop-2-en-1-yl)flavone
CHEMBL189433
1 / 1 / 0 No. 425 No. 15
C00005004 External link 512 3,5,7-Trihydroxy-4'-methoxy-8-(1,1-dimethylprop-2-en-1-yl)flavone
CHEMBL193777
1 / 1 / 0 No. 425 No. 15
C00006061 External link 512 Kaempferol 3-p-coumarate
No. 3760
C00008012 External link 512 2',4',4''-Trihydroxy-3',6'',6''-trimethylpyrano[2'',3'':6',5']dihydrochalcone
No. 5198
C00008013 External link 512 2',4',5''-Trihydroxy-3',6'',6''-trimetylpyrano[2'',3'':6',5']dihydrochalcone
No. 5198
C00007985 External link 512 Grenoblone
No. 5567
C00007986 External link 512 4-Hydroxyglenoblone
No. 5567

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08183 Multidrug resistance protein 1 drug C00004990 C00005004 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005140 C00005851 0 / 1
Q9Y253 DNA polymerase eta Enzyme C00005010 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00005010 2 / 0
O75496 Geminin Unclassified protein C00005010 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00005140 1 / 0
P11511 Cytochrome P450 19A1 Cytochrome P450 19A1 C00005010 2 / 2
P16083 Ribosyldihydronicotinamide dehydrogenase [quinone] Enzyme C00005140 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005851 1 / 1
P98170 E3 ubiquitin-protein ligase XIAP Other cytosolic protein C00005140 1 / 1
Q9UNA4 DNA polymerase iota Enzyme C00005010 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#613546 Aromatase deficiency P11511
#139300 Aromatase excess syndrome; aexs P11511
#114500 Colorectal cancer; crc P84022
#608902 Drug metabolism, poor, cyp2d6-related P10635
#612244 Inflammatory bowel disease 13; ibd13 P08183
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#300635 Lymphoproliferative syndrome, x-linked, 2; xlp2 P98170
#278300 Xanthinuria, type i P47989
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P11511 (related)
H00794 Aromatase excess syndrome P11511 (related)
H00192 Xanthinuria P47989 (related)
H00107 Other well-defined immunodeficiency syndromes P98170 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)