Calluna vulgaris
Species
KNApSAcK Entry
| Organism name | Calluna vulgaris |
|---|---|
| Genus | Calluna |
| Family | Ericaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Calluna vulgaris |
|---|---|
| Linked NCBI taxonomy ID | 13385 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Ericaceae |
|---|---|
| ID | 4345 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (13)
| Species | Activity |
|---|---|
| Calluna vulgaris (L.) Hull. | Antiinflammatory |
| Calluna vulgaris (L.) Hull. | Antilithic |
| Calluna vulgaris (L.) Hull. | Antiseptic |
| Calluna vulgaris (L.) Hull. | Astringent |
| Calluna vulgaris (L.) Hull. | Cholagogue |
| Calluna vulgaris (L.) Hull. | Depurative |
| Calluna vulgaris (L.) Hull. | Diaphoretic |
| Calluna vulgaris (L.) Hull. | Digestive |
| Calluna vulgaris (L.) Hull. | Diuretic |
| Calluna vulgaris (L.) Hull. | Narcotic |
| Calluna vulgaris (L.) Hull. | Sedative |
| Calluna vulgaris (L.) Hull. | Urinary Antiseptic |
| Calluna vulgaris (L.) Hull. | Vulnerary |
Metabolite list (15)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005349
|
Herbacetin 8-gentiobioside
|
No. 1 | No. 15 |
|
||||
|
C00005341
|
Herbacetin 8-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00005125
|
Galangin 3-methyl ether 7-glucoside
|
No. 2 | No. 15 |
|
||||
|
C00005368
|
Guaijaverin
/ Quercetin 3-O-alpha-L-arabinopyranoside |
CHEMBL183031
CHEMBL185461 CHEMBL488198 CHEMBL464507 CHEMBL520637 |
C088178
|
No. 2 | No. 15 |
|
||
|
C00014330
|
Isocarthamidin 8-glucoside
/ 5,7,8,4'-Tetrahydroxyflavanone 8-glucoside |
No. 12 | No. 14 |
|
||||
|
C00008689
|
Callunin
|
No. 12 | No. 14 |
|
||||
|
C00008690
|
2''-Acetylcallunin
|
No. 12 | No. 14 |
|
||||
|
C00009071
|
Procyanidin B3
/ Catechin-(4alpha->8)-catechin |
CHEMBL38714
CHEMBL81753 CHEMBL504937 CHEMBL501490 CHEMBL447373 CHEMBL1253314 CHEMBL1590914 |
20 / 7 / 8 | No. 16 | No. 19 |
|
||
|
C00009076
|
Procyanidin B5
/ Epicatechin-(4beta-6)-epicatechin |
CHEMBL506487
CHEMBL502984 CHEMBL451115 |
No. 16 | No. 19 |
|
|||
|
C00005971
|
Quercetin 3-(2''',3''',4'''-triacetyl-alpha-L-arabinopyranosyl)(1->6)-galactoside
|
No. 330 |
|
|||||
|
C00005975
|
Quercetin 3-(2''',3''',5'''-triacetyl-alpha-L-arabinofuranosyl)(1->6)-glucoside
|
No. 330 |
|
|||||
|
C00005976
|
Quercetin 3-(2''',3''',4'''-triacetyl-alpha-L-arabinopyranosyl)(1->6)-glucoside
|
No. 330 |
|
|||||
|
C00005880
|
Kaempferol 3-[2''',3''',4'''-triacetyl-alpha-L-arabinopyranosyl-(1->6)-glucoside]
|
No. 330 |
|
|||||
|
C00005879
|
Kaempferol 3-[2''',3''',5'''-triacetyl-alpha-L-arabinofuranosyl-(1->6)-glucoside
|
No. 330 |
|
|||||
|
C00004179
|
Apigenin 7-(2''-acetyl-6''-methylglucuronide)
|
No. 330 |
|
Human Protein / Gene in interactions
20 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00009071 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00009071 | 0 / 1 |
| P18433 | Receptor-type tyrosine-protein phosphatase alpha | Receptor tyrosine-protein phosphatase | C00009071 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00009071 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00009071 | 3 / 3 |
| P23467 | Receptor-type tyrosine-protein phosphatase beta | Receptor tyrosine-protein phosphatase | C00009071 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00009071 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00009071 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00009071 | 0 / 1 |
| Q05513 | Protein kinase C zeta type | Iota | C00009071 | 0 / 0 |
| Q04759 | Protein kinase C theta type | Delta | C00009071 | 0 / 1 |
| Q02156 | Protein kinase C epsilon type | Eta | C00009071 | 0 / 0 |
| O94806 | Serine/threonine-protein kinase D3 | Pkd | C00009071 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00009071 | 0 / 0 |
| Q05655 | Protein kinase C delta type | Delta | C00009071 | 0 / 0 |
| P05129 | Protein kinase C gamma type | Alpha | C00009071 | 1 / 1 |
| P05771 | Protein kinase C beta type | Alpha | C00009071 | 0 / 0 |
| P24723 | Protein kinase C eta type | Eta | C00009071 | 1 / 0 |
| P41743 | Protein kinase C iota type | Iota | C00009071 | 0 / 0 |
| Q15139 | Serine/threonine-protein kinase D1 | Pkd | C00009071 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #605361 | Spinocerebellar ataxia 14; sca14 |
P05129
|
| #601367 | Stroke, ischemic |
P24723
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00063 | Spinocerebellar ataxia (SCA) |
P05129
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00408 | Type I diabetes mellitus |
Q04759
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|