Astragalus centralpinus
Species
KNApSAcK Entry
| Organism name | Astragalus centralpinus |
|---|---|
| Genus | Astragalus |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Astragalus |
|---|---|
| Linked NCBI taxonomy ID | 20400 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (4)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00005531
|
Isorhamnetin 7-rhamnoside
|
No. 2 | No. 15 |
|
||||
|
C00005525
|
Isorhamnetin 3-glucoside
/ Isorhamnetin 3-O-glucoside / Isorhamnetin 3-O-beta-D-glucoside / Isorhamnetin 3-O-beta-D-glucopyranoside |
CHEMBL234316
CHEMBL516621 |
1 / 1 / 0 | No. 2 | No. 15 |
|
||
|
C00004650
|
Quercetin 3,5,7,3'-tetramethyl ether
/ 3,5,7,3'-Tetramethoxy-4'-hydroxyflavone / 2-(4-Hydroxy-3-methoxyphenyl)-3,5,7-trimethoxy-4H-1-benzopyran-4-one |
CHEMBL361803
|
No. 8 | No. 15 |
|
|||
|
C00004531
|
3,7-Dihydroxyflavone
|
CHEMBL210276
|
16 / 12 / 15 | No. 76 | No. 15 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P29466 | Caspase-1 | C14 | C00004531 | 0 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00004531 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00004531 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00004531 | 0 / 0 |
| P27487 | Dipeptidyl peptidase 4 | S9B | C00004531 | 0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00004531 | 0 / 0 |
| P18054 | Arachidonate 12-lipoxygenase, 12S-type | Enzyme | C00004531 | 2 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00004531 | 3 / 3 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00004531 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00004531 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00004531 | 0 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00004531 | 4 / 3 |
| P08908 | 5-hydroxytryptamine receptor 1A | Serotonin receptor | C00005525 | 1 / 0 |
| P48147 | Prolyl endopeptidase | S9A | C00004531 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004531 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00004531 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004531 | 1 / 2 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (13)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #114500 | Colorectal cancer; crc |
P18054
|
| #133239 | Esophageal cancer |
P18054
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #614674 | Periodic fever, menstrual cycle-dependent |
P08908
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
KEGG DISEASE (15)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00032 | Thyroid cancer |
P27487
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|