PCIDB

Skimmia laureola

Species

KNApSAcK Entry

Organism name Skimmia laureola
Genus Skimmia
Family Rutaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Skimmia laureola
Linked NCBI taxonomy ID 354518
Linked level species

Family

Family in NCBI taxonomy Rutaceae
ID 23513

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00000583 External link 512 Isopimpinellin
CHEMBL140796
C015304
9 / 3 / 4 2 / 0 No. 606 No. 25
C00026362 External link 512 (+)-Ribaliprenylene
No. 816 No. 7
C00010913 External link 512 (-)-Carvomenthene
/ (-)-p-Mentha-1-ene
No. 1052 No. 35
C00050204 External link 512 Ptelefoliarine
/ (-)-Ptelefoliarine
No. 1903 No. 7
C00026473 External link 512 Orixiarine
No. 2346

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P06746 DNA polymerase beta Enzyme C00000583 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00000583 0 / 0
P56817 Beta-secretase 1 A1A C00000583 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000583 2 / 2
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000583 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000583 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000583 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000583 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000583 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000583
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00000583

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#119900 Digital clubbing, isolated congenital P15428
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428

KEGG DISEASE (4)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)